Orientador: Ariel Antônio Mendes / Coorientador : Márcia Regina Fernandes Boaro Martins / Banca: José Roberto Sartori / Banca: Ibiara Correia de Lima Almeida Paz / Resumo: Com o objetivo de avaliar a pododermatite e o desempenho em frangos de corte, foram alojados em aviário experimental da FMVZ-UNESP/Botucatu 750 frangos de corte machos da linhagem Cobb®, com densidade populacional de 12 aves/m2, por 42 dias. O delineamento experimental adotado foi inteiramente casualizado com cinco tratamentos e cinco repetições de 30 aves cada, totalizando 25 parcelas experimentais. Os tratamentos foram constituídos por duas fontes de suplementação de vitamina D (D3 e 25-OHD3). O tratamento 1, controle, seguiu as recomendações de Rostagno et al. (2011) para a vitamina D3, de acordo com cada fase de criação para frangos de corte. O tratamento 2 foi constituído de vitamina D3 (mesma dosagem do tratamento controle) + 1.400 UI de 25-OHD3; o tratamento 3 foi constituído de vitamina D3 (mesma dosagem do tratamento controle) + 2.800 UI de 25-OHD3; o tratamento 4 e o tratamento 5 foram constituídos apenas de vitamina D3 e, seus valores foram baseados na soma das doses em UI das duas fontes de vitamina D do tratamento 2 e do tratamento 3, respectivamente. Para o desempenho das aves foi calculado o consumo de ração, ganho de peso e conversão alimentar durante todo o período de criação, ao final foi calculada a viabilidade e o índice de eficiência produtiva. Aos 42 dias, 100 aves de cada tratamento foram avaliadas, no aviário, para pododermatite. Posteriormente as aves foram abatidas e realizadas análises histopatológicas do coxim plantar. Houve diferença pelo Teste de Quiquadrado (p<0,05) para a avaliação da incidência de pododermatite apenas para a perna esquerda. Os tratamentos não influenciaram o desempenho das aves e não foi observada diferença histopatológica entre lesões iniciais e severas, exceto em sua extensão. Conclui-se que as suplementações de... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Seven hundred and fifty Cobb® male broiler chickens were kept in a population density of 12 birds / m2 in the experimental aviary of FMVZ-UNESP/Botucatu during 42 days to evaluate the lesions of pododermatitis and performance. The experiment was carried out in a completely randomized design with five treatments and five repetitions of 30 birds each, totalizing 25 experimental parcels. Treatments were consisted of two sources of vitamin D (D3 and 25-OHD3). The first treatment (T1- control) followed the recommendations of Rostagno et al. (2011) for vitamin D3 according to each life stage of broiler chickens. Treatment 2 was the combination of vitamin D3 (the same level of control treatment) and 1,400 UI of 25-OHD3; treatment 3 was consisted of vitamin D3 (the same level of control treatment) and 2,800 UI of 25-OHD3; treatment 4 and 5 were consisted of only vitamin D3 and the levels were based on the sum of levels from the two sources of vitamin D3 of treatment 2 and 3, respectively. Feed intake, weight gain and feed:gain rate were calculated to evaluate the performance of broilers throughout the breeding period, viability and production efficiency index were also evaluated at the end. Pododermatitis and histological analyses of footpad were evaluated from one hundred broilers at 42 days of age. Through the Chi-Square Test (P<0.05) it could be seen a difference for pododermatitis incidence only for the left leg. Treatments did not affect the broiler performance and it was not observed histopathological differences between initial and severe lesions, except in its extension. In conclusion the supplementation of vitamin D3... (Complete abstract click electronic access below) / Mestre

The very virulent (vv) pathotype of infectious bursal disease virus (IBDV) has spread rapidly throughout Europe, Asia, and the Middle East. Although Australia is currently unaffected, there remains the potential for incursion of an exotic isolate. The aim of this study was to identify putative virulence determinants of IBDV to facilitate the development of improved diagnostic assays for detection and characterisation of vvIBDV isolates. Sequencing of Indonesian vvIBDV Tasik94 revealed a unique substitution [ A¨S222] in the hypervariable region (HVR) of viral protein (VP) VP2, which did not appear to impinge on virulence or antigenicity. Phylogenetic analyses indicated that Tasik94 was closely related to Asian and European vvIBDV strains. Extensive alignment of deduced protein sequences across the HVR of VP2 identified residuesI242 I256 and I294 as putative markers of the vv phcnotype. Comparison of the pathology induced by mildly-virulent Australian IBDV 002/73 and Indonesian vvIBDV Tasik94, revealed that histological lesions in the spleen, thymus and bone marrow were restricted to Tasik94-infected birds, suggesting the enhanced pathogenicity of vvIBDV might be attributed to replication in non-bursal lymphoid organs. The biological significance of the VP2 HVR in virulence was assessed using recombinant viruses generated by reverse genetics. Both genomic segments of Australian IBDV 002/73, and recombinant segment A constructs in which the HVR of 002/73 was replaced with the corresponding region of either tissue culture-adapted virus or vvIBDV (Tasik94), were cloned behind T7 RNA polymerase promoter sequences. In vitro transcription/translation of each construct resulted in expression of viral proteins. Co-transfection of synthetic RNA transcripts initiated replication of both tissue culture-adapted parental and recombinant viruses, however attempts to rescue non-adapted viruses in specific-pathogen-free (SPF) chickens were unsuccessful. Nucleotide sequence variation in the HVR of VP2 was exploited for the development of a new diagnostic assay to rapidly detect exotic IBDV isolates, including vvIBDV, using reverse transcription polymerase chain reaction (RT-PCR) amplification and Bmrl restriction enzyme digestion. The assay was capable of differentiating between endemic and exotic IBDV in 96% of 105 isolates sequenced to date.

No description available.

Ingestion of contaminated chicken meat is a major cause of Campylobacteriosis in Europe and the USA. The environment, including wild birds, is considered to be an important reservoir for chicken colonization. The aims of this study were to determine the population structure of Campylobacter amongst chicken and wild bird sources on a single farm, and to establish the extent to which genotypes flow between them and ultimately infect humans, using MLST and antigen sequence typing. A pilot study amongst farm animals and wild birds in Lancashire demonstrated that Campylobacter genotypes from human disease were common on the farm and could be isolated from more than one animal source. Between 30-50% of wild geese and Starlings were shedding Campylobacter, with a seasonal peak in shedding rate in Spring. Genotypes were divergent from those previously isolated from human disease, retail meat and farm animal sources, with the majority being restricted to the host source. The carriage rate of Campylobacter was between 70- 100% amongst 78 free-range poultry flocks tested at 56 days of age. Up to seven genotypes were found to co-exist within a flock, and genotypes varied throughout the year on a random basis. Some Campylobacter strains were isolated from one farm site only, but a small percentage of them had spread nationally and were stable over a period of a decade. A total of 23% of Campylobacter isolates from free-range chickens were indistinguishable to those from human disease, and 5% were indistinguishable from wild birds. A total of 6% of genotypes isolated from wild birds were indistinguishable from those isolated from human disease. Wild birds could not be completely disregarded as a potential reservoir of Campylobacter for both humans and poultry, but their role is likely to be limited.

Irregular pagination: jumps from xix to 21 / New Zealand maintains the highest incidence rate of human campylobacteriosis of the industrialized countries (334.2 cases per 100,000 in 2002), it accounts for more than 56% of all disease notifications in the country. New Zealand is unique globally, with a 'notification-based surveillance system for notifiable diseases that is complemented by laboratory reporting. In other countries (Australia, US, UK), the notification system is entirely laboratory based. Thus, the high incidence of Campylobacteriosis in humans may be related to the methods of reporting rather than the reality of the disease situation. However, the reason for such high incidence has not yet been fully elucidated, and several studies conducted in New Zealand and overseas have implicated the consumption of poultry meat as the main cause of human infections. The reduction or elimination of Campylobacter jejuni in the food chain, particularly from poultry meat products, is a major strategy in efforts to control campylobacteriosis. One approach to this is to prevent C. jejuni colonization of broiler chickens, This approach has been used to control Salmonella contamination of poultry, but the measures put in place for control of Salmonella have not controlled C jejuni. It is generally unknown how frequently C. jejuni colonizes commercial broiler chickens in New Zealand, or what could be done to prevent these infections from occurring. The present study was undertaken in order to describe some of the basic epidemiology of C. jejuni in commercial broiler flocks in New Zealand. The thesis is intended to further describe the epidemiology of colonisation of commercial broiler chickens by C. jejuni in NZ, and present possible risk factors that could be controlled in future to decrease the number of positive flocks of birds that are processed. The thesis set out to elucidate first the extent of C. jejuni colonisation of birds, flocks and farms while the birds were on the farm, having had minimal risk of exposure to Campylobacter spp., by sampling 15 birds in 80 flocks belonging to two companies prior to the first partial depopulation, an event during which the flock are exposed to potentially contaminated fomites and biosecurity levels are dropped, doors opened and personnel movements are extensive. The resulting prevalence estimates are 25.6% of farms, and 12.5% of sheds, are likely to be used to rear broiler chickens colonised with C. jejuni. When a positive flock is discovered, 76.9% of the birds are likely to be colonised with C. jejuni. These figures are results across the whole study population of farms and sheds, as there were no significant differences between prevalence estimates between companies. Following this prevalence estimation, a longitudinal study was conducted involving 12 sheds, to determine whether the environment or the birds were colonised with C. jejuni first. Although 12 sheds were observed every other day from day 14 to the end of the rearing period, it was determined that the birds were positive either first, or at the same time as the environment. Having said that, the sensitivity of the testing method for the environment was dubious, as there were instances where a shed that had positive samples collected on one occasion appeared negative the next, before returning a positive result on the third consecutive sampling occasion. A cross-sectional study of 810 flocks was undertaken to determine the most relevant risk factors for colonisation of the broiler chickens with C. jejuni. Because of the vertically integrated structure of the poultry industry, these 810 flocks corresponded to data collected from 77 farmers about their farms and the 219 sheds on those farms. The caeca from ten birds from each flock processed were pooled and examined for the presence of C. jejuni. These results were used to create a case definition, such that the flocks could be analysed with the questionnaire data, and different risk factors were seen in each season. More flocks reared for Company One were colonised by C. jejuni than for Company Two. Protective factors included having hard (i.e. gravel, asphalt or concrete) pathways to the growout houses, being near to another broiler farm, using the reticulated town water supply for the birds drinking water, using tunnel or crossflow shaped growout houses, using a Chore-TimeTM feed delivery system within the growout house and chlorinating the water supply to the birds (only in winter). The odds of raising flocks colonised with C jejuni increased if rodents were seen on the farm, if the growout houses were constructed with a concrete nib wall, if gas heaters were used during brooding, if cattle were farmed on the property, or if workers were employed on the farm. Sanitising the annex at least as frequently as once per run decreased the odds during summer, and tended to have a similar effect in other seasons. Chlorinating the water supply appeared to have a protective effect in only one season, though the trend appeared towards protection in the other seasons. The risk factor was validated by sampling the drinking water that broilers chickens had access to for the FAC to sec whether the levels that were present in the drinking water could have an effect on C. jejuni 11 sheds that were known to chlorinate the water were sampled to determine whether they met the drinking water standards for humans in NZ, or met the requirements presented by one of the companies involved. Only three sheds met the human drinking water standards for FAC, and two of these (one from each company) met Company Two's requirements. This thesis is for both regulatory and industry stakeholders to assist with developing risk management approaches to diminishing the number of C. jejuni positive flocks. Where management practices are altered, it is hoped that the efficacy of such practices be measured by examining the changes in the rates of C jejuni colonization within the industry

Orientador: Fernando Antônio de Ávila / Banca: Caroline Peters Pigatto De Nardi / Banca: Patrícia Amoroso de Andrade / Banca: Hélio José Montassier / Banca: José Moacir Marin / Resumo: As condições de criação de galinhas de fundo de quintal (GFQ) apresentam alto risco sanitário, já que medidas de biossegurança nem sempre são implementadas nessas criações. Dentre as doenças infecciosas de grande destaque na avicultura está a colibacilose, cujo agente envolvido é Escherichia coli patogênica aviária (APEC). Essa enfermidade está ligada à maneira e ao ambiente em que as aves são criadas, sendo que alguns isolados de APEC podem causar infecções nas próprias aves e em humanos. O mecanismo de virulência das amostras de APEC tem sido continuamente estudado e acredita-se ser multifatorial. O objetivo do trabalho foi detectar e caracterizar isolados potencialmente APEC em criações de GFQ. Para isto foram coletadas amostras cloacais e orofaríngeas de 250 GFQ, provenientes de sete pequenas propriedades da região de Ribeirão Preto - SP. Das 500 amostras, foram obtidos 69 isolados de E. coli positivos para pelo menos 5 genes característicos de APEC. Estes foram submetidas à PCR para a detecção de mais 11 genes de virulência, apresentando alta prevalência dos mesmos. A inoculação in vivo em pintainhos de um dia revelou que 49 destes isolados são de alta e/ou intermediária patogenicidade. Os isolados também foram submetidos ao teste de suscetibilidade a 17 antimicrobianos, e apresentaram resistência a pelo menos um antimicrobiano e a maioria (79,7%) apresentou perfil de multirresistência. Além disso, foi realizada análise filogenética e foi observado que 53,6% dos isolado... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The conditions of backyard chickens creation (BC) present a high sanitary risk, since biosafety measures are not always implemented in these systems. Among the most important infectious disease in poultry is colibacillosis, and avian pathogenic Escherichia coli (APEC) is the causative agent. This disease is related to the way and environment in which these birds are created, and some APEC isolates can cause infection in birds and humans. The virulence mechanism of APEC samples has been continuously studied and probably is multifactorial. The objective of this work was to detect and characterize potentially APEC isolates in BC creations. For that, it were collected cloacal and oropharyngeal samples of 250 BC, from seven small properties from Ribeirão Preto - SP. Of the 500 samples, 69 positive E. coli isolates were obtained for at least 5 characteristic genes of APEC. These isolates were submitted to PCR for detection of 11 more virulence genes, resulting in a high prevalence of them. The test of inoculation in one day-old chicks revealed that 49 of these isolates had high and/or intermediate pathogenicity. All isolates were also submitted to the susceptibility testing on 17 antimicrobials, and showed resistance to at least one antimicrobial agent, but the most of them (79.7%) had a multiresistance profile. In addition, phylogenetic analysis was performed and 53.6% of the isolates belonged to B2 group, which has already been described as the group harboring isolates that cause extraintestinal infections. In pulsified gel electrophoresis analysis (PFGE), it was detected a high heterogeneity of pulse types among the APEC isolates and only one sample was non-typable for XbaI enzyme. Furthermore, 15 serogroups were identified among the isolates, and O8 was the most frequent (23.2%). The results obtained in this study demonstrated that BC are (Complete abstract click electronic access below) / Doutor

Made available in DSpace on 2014-06-11T19:27:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-04-25Bitstream added on 2014-06-13T19:56:26Z : No. of bitstreams: 1 bresne_c_me_botfmvz.pdf: 918891 bytes, checksum: decfbf9bcf0c32e25e4bb4c917c76fc2 (MD5) / Com o objetivo de avaliar a pododermatite e o desempenho em frangos de corte, foram alojados em aviário experimental da FMVZ-UNESP/Botucatu 750 frangos de corte machos da linhagem Cobb®, com densidade populacional de 12 aves/m2, por 42 dias. O delineamento experimental adotado foi inteiramente casualizado com cinco tratamentos e cinco repetições de 30 aves cada, totalizando 25 parcelas experimentais. Os tratamentos foram constituídos por duas fontes de suplementação de vitamina D (D3 e 25-OHD3). O tratamento 1, controle, seguiu as recomendações de Rostagno et al. (2011) para a vitamina D3, de acordo com cada fase de criação para frangos de corte. O tratamento 2 foi constituído de vitamina D3 (mesma dosagem do tratamento controle) + 1.400 UI de 25-OHD3; o tratamento 3 foi constituído de vitamina D3 (mesma dosagem do tratamento controle) + 2.800 UI de 25-OHD3; o tratamento 4 e o tratamento 5 foram constituídos apenas de vitamina D3 e, seus valores foram baseados na soma das doses em UI das duas fontes de vitamina D do tratamento 2 e do tratamento 3, respectivamente. Para o desempenho das aves foi calculado o consumo de ração, ganho de peso e conversão alimentar durante todo o período de criação, ao final foi calculada a viabilidade e o índice de eficiência produtiva. Aos 42 dias, 100 aves de cada tratamento foram avaliadas, no aviário, para pododermatite. Posteriormente as aves foram abatidas e realizadas análises histopatológicas do coxim plantar. Houve diferença pelo Teste de Quiquadrado (p<0,05) para a avaliação da incidência de pododermatite apenas para a perna esquerda. Os tratamentos não influenciaram o desempenho das aves e não foi observada diferença histopatológica entre lesões iniciais e severas, exceto em sua extensão. Conclui-se que as suplementações de... / Seven hundred and fifty Cobb® male broiler chickens were kept in a population density of 12 birds / m2 in the experimental aviary of FMVZ-UNESP/Botucatu during 42 days to evaluate the lesions of pododermatitis and performance. The experiment was carried out in a completely randomized design with five treatments and five repetitions of 30 birds each, totalizing 25 experimental parcels. Treatments were consisted of two sources of vitamin D (D3 and 25-OHD3). The first treatment (T1- control) followed the recommendations of Rostagno et al. (2011) for vitamin D3 according to each life stage of broiler chickens. Treatment 2 was the combination of vitamin D3 (the same level of control treatment) and 1,400 UI of 25-OHD3; treatment 3 was consisted of vitamin D3 (the same level of control treatment) and 2,800 UI of 25-OHD3; treatment 4 and 5 were consisted of only vitamin D3 and the levels were based on the sum of levels from the two sources of vitamin D3 of treatment 2 and 3, respectively. Feed intake, weight gain and feed:gain rate were calculated to evaluate the performance of broilers throughout the breeding period, viability and production efficiency index were also evaluated at the end. Pododermatitis and histological analyses of footpad were evaluated from one hundred broilers at 42 days of age. Through the Chi-Square Test (P<0.05) it could be seen a difference for pododermatitis incidence only for the left leg. Treatments did not affect the broiler performance and it was not observed histopathological differences between initial and severe lesions, except in its extension. In conclusion the supplementation of vitamin D3... (Complete abstract click electronic access below)

The possibilities of transmission of infectious synovitis were explored. Two types of tests, using mosquitoes as vectors, were employed. One type involved the feedings of mosquitoes on previously inoculated birds, then after a period of from zero to ninety-six hours refeeding the mosquitoes on assay birds. The second type of insect test comprised the feeding of mosquitoes on inoculated birds, then macerating and inoculating them into check birds at intervals of one to twenty-one days following feeding. Other experiments were conducted in which uninoculated birds were brought into close contact with inoculated chickens and their excrement. The observation of all tests indicated the absence of transmission of an infective titer of the infectious synovitis agent. These conclusions are drawn from tests using Aedes aegypti (Linn.) and Culex fatigans Wied., with methods and materials described. / Master of Science

Eight studies of the epidemiological dynamics of avian influenza viruses were conducted on poultry in Hong Kong, with special focus on the movement of birds through the live poultry marketing system, and the implications for avian influenza transmission. The first involved analysis of virus isolation data from faecal samples obtained from cooperating stalls in live poultry markets in Hong Kong in a routine sampling program undertaken between 1999 and 2001. This showed that two subtypes of avian influenza viruses, H9N2 and H6N1, have become well established in the Hong Kong live poultry markets, especially in chickens (mainly H9N2) and quail (mainly H6N1). In addition, a wave of H5N1 virus infection occurred in 2001 after it had been absent through the earlier period of the study. The second study was an evaluation of long term changes in the marketing systems for live poultry in Hong Kong, their likely effects on avian influenza epidemiology, and documented evidence of the prevalence of various H subtypes of avian influenza in sampling undertaken during three periods from 1975 to 2001. The third project involved two cross-sectional studies and one longitudinal study on local quail farms in Hong Kong. Results showed that quail could act as a reservoir host for H9N2 and H6N1 subtype viruses, but each subtype differed in its epidemiology. H9 virus usually infected quail at around 10 days of age, whereas H6 infected quail at 15-20 days of age. At 35 days of age (usual market age in Hong Kong), a proportion of market quail were likely to be susceptible to H6 (50%) and H9 viruses (20%), and were able to transmit the virus in the markets. Due to these findings, the Hong Kong Government closed the quail farming operations and restricted the sale of quail in live poultry markets. A longitudinal study was conducted on three live poultry market stalls to assess the time from stall entry to sale, and evaluate the influence of this delay on avian influenza virus transmission to other poultry in the same stall. Participating stalls varied from high volume/rapid turnover to low volume/slow turnover. Turnover for tagged poultry was rapid, although some chickens became infected with H9 virus before sale. Birds which stayed longer, such as quail, became infected and maintained infection in the stall. As well as spread by direct contact and on typical fomites, keeping of pet roosters and re-use of washing water were identified as factors increasing the ability of avian influenza strains to persist in market stalls. An experimental replica of a market stall was created to study the transmission of low pathogenic avian influenza virus (H9N2) in a controlled environment, with different rates of population turnover and different immune status with respect to both H5 and H9 subtypes. Transmission was influenced by distance between birds, the proportion of birds carrying antibody to H9 and the rate of introduction of susceptible birds, but not by the use of H5N2 vaccine. In order to assess the effectiveness of temporary depopulation of stalls, a study was conducted to compare the prevalence of avian influenza virus and Newcastle disease virus before and shortly after the monthly rest day in live poultry markets in Hong Kong, by virus isolation. Prevalence of H9N2 avian influenza virus was reduced by the rest day, but Newcastle disease virus prevalence was unaffected. During the 2002 avian influenza H5N1 outbreak in local chicken farms, a case-control study was undertaken to identify risk factors that may have contributed to this outbreak. A questionnaire was administered by interview to collect the data for this study. Multivariate logistic regression models showed that movement of people and fomites from live poultry markets to farms were important influences on transmission, and that the live bird markets were the likely source of virus for farms. A spatial stochastic computer model was constructed to predict the spread of avian influenza virus in local chicken farms and live poultry markets in Hong Kong, and the effectiveness of control measures. The data used in model parameter setting was derived from the case-control study. The reference model produced an epidemic curve which was similar to the true epidemic curve in the 2002 outbreak. Control strategies such as rest day and vaccination were evaluated within the model, and found to produce results comparable with field experience. Results from these studies clarify various aspects of the epidemiological features and transmission dynamics of avian influenza viruses, and provide guidance on appropriate control and prevention strategies for highly pathogenic avian influenza viruses within poultry marketing systems in Asia.

Orientador: Irenilza de Alencar Nääs / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Agricola / Made available in DSpace on 2018-08-04T17:21:01Z (GMT). No. of bitstreams: 1 Lima_AnnaMonteiroCorreia_D.pdf: 727089 bytes, checksum: 35dbabd5e5be44e560b02060dfe791b0 (MD5) Previous issue date: 2005 / Resumo: O aumento de produção que levou o Brasil a ocupar a posição de segundo maior produtor de frangos de corte do mundo se deve a intensificação de criação. Essa intensificação teve como base vários aspectos que foram cuidadosamente controlados, dentre eles a nutrição e o manejo (sistemas de criação, ambiência, sanidade etc). Atualmente o que se observa em várias partes do mundo é a tendência em produzir frangos de corte, com bem estar animal. Paralelamente no Brasil, vem ressurgindo em nova versão a criação de frangos caipiras. O objetivo desse estudo foi avaliar índices zootécnicos obtidos durante a produção de dois sistemas de frango de corte em escala comercial (In situ), um intensivo, convencional (granja A) e outro semi-extensivo, caipira (granja B), para verificar as inter-relações entre bem-estar animal, manejo, saúde animal e qualidade da carne. Na granja A foram alojados 14000 pintos enquanto que na granja B foram 7150. Observou-se que frangos da granja A apresentaram mais problemas locomotores: calos de pés, discondroplasia tibial quando comparados com frangos provenientes da granja B. Os frangos da granja A apresentaram alta prevalência de necrose da cabeça do fêmur, melhor conversão alimentar e ganho de peso, embora tenham apresentado maior mortalidade A e B, foram respectivamente 5,32 e 1,34%. Quanto a Salmonella sp. e Mycoplasma sp. não houve presença de frangos reagentes nas duas granjas. Quanto à qualidade da carne em termos físico-químicos, o pH do peito apresentou-se menor significativamente para carcaças de frangos provenientes da granja A, enquanto o pH da coxa não apresentou diferença significativa. A força de cisalhamento da carne de frango proveniente da granja A apresentou-se menor, quando comparada à de carcaças de frangos da granja B (1,972 para carcaças de A e 2,462 para as de B). A capacidade de retenção de água não diferiu entre as carcaçaa provenientes das granjas. Em termos microbiológicos a Salmonella sp. não foi encontrada em nenhuma carcaça de frango, embora a Listeria sp. tenha sido encontrada em 50% das carcaças analisadas. Os frangos da granja B estiveram em melhores condições de bem-estar animal. Com base nesses resultados foi possível estimar que os índices zootécnicos da granja A foram melhores que os da granja B, entretanto os problemas locomotores foram maiores nos frangos provenientes da granja A / Abstract: The increase in production technology was the major factor that lead Brazil to be the second largest world poultry producer. This production technology had the basis several aspects that were carefully controlled, among them nutrition and management (environment, health and rearing systems). Nowadays it is observed a world¿s tendency to produce animal searching good welfare conditions. In parallel in Brazil is growing a new version of extensive produced broilers (free-range broiler). The objective of this study was to evaluate the production indexes from two distinct industrial scale broiler productions (in situ): one intensive (farm A) and other semi-extensive (farm B) for verifying the inter-relations among welfare, management, health and meat quality (14000 broilers in farm A and 7150 broilers in farm B). It was observed that birds from farm A showed more leg weakness (foot burn and tibial dyschondroplasia) when compared with broiler from farm B. The broilers from farm A presented high prevalence of femur necrosis, higher feed conversion, and higher gain weight, although they had presented higher mortality (5,32 in farm A and 1,34% in farm B.). Regarding Salmonella sp and Mycoplasma sp it was not found serological reagent birds in neither of the studied farms. Regarding meat quality (in the physical chemistry analysis) the breast meat pH from farm A¿s birds presented values significantly smaller than the bird¿s carcass from farm B. The shearing force on meat from broiler reared at farm A were smaller than the ones from birds reared at farm B (1,972 farm A e 2,462 farm B).. Water holding capacity did not differ from the carcasses from both farms. In microbiological terms Samonella sp was not found the studied carcasses, however Listeria sp was found in 50% of the analyzed carcasses. About welfare conditions broilers from farm B were better. Based on these results it was possible to estimate that production index was better in farm A than in farm B, however leg weakness problems were higher in broilers from farm B / Doutorado / Construções Rurais e Ambiencia / Doutor em Engenharia Agrícola