La pollution sonore est un problème majeur pour les résidents des zones urbaines. La directive Européenne 2002/49/CE impose aux états membres l’établissement de cartes de bruit. Ces dernières sont construites sur la base de l’indice énergétique Lden, également utilisé dans les relations dose-effet établies pour prédire la gêne. Toutefois, pour l’évaluation de la gêne due au bruit dans les zones urbaines, la pertinence de cet indice est souvent remise en question. En effet, de nombreuses études ont montré que les caractéristiques temporelles et spectrales des bruits environnementaux influencent aussi les réponses de gêne et ne sont pas prises en compte dans cet indice. Cette thèse vise à contribuer à l’amélioration de la caractérisation de la gêne due au bruit des véhicules routiers en ville. Elle est basée sur des expériences réalisées en laboratoire. Elle comprend deux parties principales. La première partie a comme objectif de progresser sur la caractérisation physique et perceptive du bruit des passages de divers véhicules routiers en milieu urbain tels que les bus, les deux-roues motorisés, les poids lourds et les véhicules légers. Une attention particulière a été portée sur la caractérisation de la gêne due aux deuxroues motorisés qui sont cités parmi les véhicules routiers les plus gênants et sont peu étudiés dans la littérature. Dans cette perspective, un indicateur acoustique caractéristique de la gêne due au bruit routier urbain a été déterminé : il rend compte de différents attributs auditifs gênants en associant la sonie, un indice spectral et deux indices de modulation proposés dans le cadre de ces travaux. Dans les zones urbaines, les riverains sont souvent exposés à la circulation routière en présence d’autres sources de bruit de l’environnement. L’objectif principal de la deuxième partie est la prédiction de la gêne totale due au bruit du trafic routier urbain combiné avec le bruit de tramway. Dans le but de caractériser la gêne totale, les phénomènes perceptifs liés à la combinaison de ces bruits sont tout d’abord étudiés. Ensuite, l’indicateur proposé précédemment pour caractériser la gêne due au bruit des passages de différents véhicules routiers est testé lorsque différents trafics routiers urbains sont considérés. Sur la base de ces résultats, des modèles permettant de caractériser la gêne due au bruit de trafic routier urbain combiné au bruit de tramway ont été proposés. / Noise pollution is a major concern for residents of urban areas. To date, the European directive 2002/49/CE requires member states to represent community noise through noise maps. These are produced using the Lden (day-evening-night level) index which is also employed for dose-effect relationships in noise annoyance prediction. However, for the assessment of noise annoyance in urban areas, its relevance is often questioned. Numerous studies have shown that noise annoyance due to community noise is not solely based on the sound pressure level and other acoustical signal characteristics such as temporal and spectral features influence noise annoyance ratings. This thesis aims to improve the assessment of noise annoyance due to various road vehicle noises in cities. It is based on experiments carried out in laboratory conditions and comprises two main parts. The first addresses the enhancement of the physical and perceptual characterization of annoyance due to various urban road vehicle pass-by noises, such as buses, poweredtwo- wheelers, heavy vehicles and light vehicles. A specific focus is put on the characterization of annoyance due to powered-two-wheelers which are among the most annoying road vehicles and studied little in the existing literature. An indicator accounting for annoyance-relevant auditory attributes of urban road vehicle pass-by noises is determined: it comprises loudness, a spectral index and two modulation indices proposed in this work. In urban agglomerations, people are often exposed to road traffic in presence of a variety of other environmental noise sources. The focal point of the second part is on the prediction of total annoyance due to urban road traffic noise combined with tramway noise. In the aim of adequately characterizing total annoyance, first the perceptual phenomena involved in annoyance due to the combination of the sources are studied. Furthermore, the analysis allows for the testing of the proposed noise annoyance indicator for the characterization of urban road traffic noise. To characterize annoyance due to tramway noise, an indicator determined in a recent study is employed. Based on these indicators and the findings regarding perceptual phenomena, models for the prediction of total annoyance due to combined urban road traffic and tramway noise are proposed.

Sport Airport complex Brno-Medlánky is nestled in the undulating hilly terrain in fields just beyond populated areas in Brno-Medlánky. The history of the airport dates back to 1924 when it was built the first wooden hangar for training purposes glider flights. Current state urban of airport is orderless. The aim is to streamline the complex and give it the order, allowing easy and efficient orientation in the space. The main intervention was the creation of a new central building - Aviation Museum. The concept of the design is based on the division of the whole area into two branches - communication axes, based on the mass preserved historic wooden hangars. Between the two communication arms is inserted a central axis on which is located the heart of the complex - Aviation Museum. It is a building organic form, inspiring axially symmetric wingspan (bird, airplane, beetle). It is this symmetry axis of the building creates a view towards building on the runway. Mass of the building used by the sloping terrain and is partially sunk under the ground. Building volume follows an upward slope from the outside and blends with the surrounding terrain. The internal layout consists of three floors, one of them is completely sunk below ground level and second half. The main entrance to the gallery is located in the uppermost floors, the direction of the exhibition is therefore directed downwards into the basement. The exposition is divided into six parts: RC models exposure, gliders exposure, powered aircraft exposure, screening room, children's exposure and air trainers. Other areas consist of building technical facilities. In the basement there is a workshop with aircraft lift, with the possibility of placement unexposed aircrafts. The supporting system of the building consists of two parts: reinforced concrete tubs and arched steel structure with a span of 50m.

Traditional fabrication methods used to manufacture biosensors for physiological, therapeutics, or health monitoring purposes are complex and rely on costly materials, which has hindered their adoption as single-use medical devices. The development of a new kind of wearable and implantable electronics relying on inexpensive materials for their manufacturing will pave the way towards the ubiquitous adoption of sticker-like health tracking devices.<div>One of growing and most promising applications for biosensors is the continuous health monitoring using mechanically soft, stretchable sensors. While these healthcare devices showed an excellent compatibility with human tissues, they still need highly trained personnel to perform multi-step, prolonged fabrication for several functioning layers of the device. In this dissertation, I propose low-cost, scalable, simple, and rapid manufacturing techniques to fabricate multifunctional epidermal and implantable sensors to monitor a range of biosignals including heart, muscle, or eye activity to characterizing of biofuids such as sweat. I have also used these devices as an implant to provide heat therapy for muscle regeneration and optical stimulation of neurons using optogenetics. These devices have also combined with those of triboelectric<br>nanogenerators to realize self-powered sensors for monitoring imperceptible mechanical biosignals such as respiratory and pulse rate.</div><div>Food health and safety has also emerged as another important frontier to develop biosensors and improve the human health and quality of life. The recent progresses on detecting microbial activity inside foods or their packages rely on development of highly functional materials. The existing materials for fabrication of food sensors, however,<br>are often costly and toxic for human health or the environment. In this dissertation, I proposed biocompatible food sensors using protein/PCL microfibers to reinforce the protein microfibrous structure in humid conditions and exploit their excellent hygroscopic properties to sense biogenic gas, as an indicator for early detection of food spoilage. Finally, my battery-free food sensors are capable of monitoring food safety with no need of extra measurement devices. Collectively, this dissertation proposes cost-effective solutions to solve human health issues, enabled by developing low-cost, functional materials and exploiting simple fabrication techniques.<br></div>

In the stories of olden times and in those of our own American Indians, we learned of the picture writing of primitive peoples. It became an early method of recording people's thoughts. This was a very useful method at a time when the race was young. This in turn was the beginning of our alphabet, later the beginning of shaping letters into words, and then word into sentences and paragraphs. As our world has grown older, new idea have come into use and we are no longer content to live as our grandparents lived. We travel by fast express trains, high powered auto- mobiles, airplanes, or zeppelins. The radio gives us the news before our papers containing it are on the street. are not able to talk with people on the other side of the world. Business men find this a very valuable means of doing business when time means money. The motion pictures bring us the story of the book we have not had time to read and the characters from its pages talk to us from the screen. In short, we must have quicker ways of doing things.