Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1980. / MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERING. / Bibliography: leaves 60-61. / by Gregory Paul Matthews. / M.S.

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1982. / MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERING / Bibliography: leaves 94-97. / by Daniel Michael Chernoff. / M.S.

This diploma thesis is dealing with pressure measurement. It describes instruments dedicated to purpose - pressure gauges. Basic of correct pressure measurement is knowledge of behaviour of used pressure gauge. This knowledge is acquired by calibration. With calibration is associated also analysis of errors and uncertainty of measurement and creation of calibration list. Calibration takes place on model workspace pressure measuring in laboratory.

京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第20050号 / 医博第4158号 / 新制||医||1018(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 坂井 義治, 教授 松田 秀一, 教授 安達 泰治 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

Blood pressure (BP) monitoring is an important tool for management of hypertension, which is a significant risk for cardiovascular disease and premature death. Since cuff-based BP measurement can be uncomfortable and does not provide continuous readings, several cuffless methods that are typically based on within-beat information or on the pulse transit time (PTT) have recently been investigated. This work proposes a novel cuffless BP estimation approach that mainly uses the information from cardiovascular dynamics of photoplethysmogram (PPG) waveforms. This work is divided into three parts. The first part proposes a calibration-free approach that uses dynamic changes in the pulse waveform. Results from 200 patients showed that the method achieved grade B, in terms of accuracy, for diastolic blood pressure (DBP) based on the British Hypertension Society (BHS) standard and complied with the accuracy requirements of the Association for Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) standard. The second part presents a method based on calibrated cardiovascular dynamics, achieved through a mathematical model that relates reflective PTT (R-PTT) to BP. Results from 30 patients showed a mean error (ME) of 0.58 mmHg, standard deviation of the error (SDE) of 8.13 mmHg, and a mean absolute error (MAE) of 4.93 mmHg for DBP and an ME of 2.52 mmHg, SDE of 12.28 mmHg, and an MAE of 8.82 mmHg for systolic blood pressure (SBP). The third part proposes a calibration-free method that combines morphology features and dynamic changes of the pulse waveform over short intervals. In this method a neural network was trained on 200 patients and tested on never-seen data from 25 other patients and provided an ME of -0.31 mmHg, SDE of 4.89 mmHg, and MAE of 3.32 mmHg for DBP and an ME of -4.02 mmHg, SDE of 10.40 mmHg, and MAE of 7.41 mmHg for SBP. Overall, the results show that cardiovascular dynamics may contribute useful information for cuffless estimation of BP.

This paper proposes a torque sensor based on the differential air pres- sure measurement method using a new embedded structure. The pro- posed sensor design is an improvement over the previous sensor design. The mechanical sensitivity, resolution, and stress distribution of the new sensor are analyzed by finite element modeling. Based on the simulation results, a new mechanical sensing shaft body and its internal embedded parts were fabricated. The feasibility of the proposed embedded struc- ture is explored, and a sealing method based on this structure is pro- posed. In order to make the readout circuit of the differential pressure sensor embedded in the shaft body, the readout circuit PCB was rede- signed, and its power consumption was studied. To verify the design, the prototype sensor was measured at a static torque. The experimental results show that gas sealing of the sensor can be achieved using the proposed embedded structure and sealing method. The sensitivity of the mechanical design of the sensor is 249.23Pa/N·m, and the range is ±25N·m. The effect of using differential input to achieve common mode rejection is verified by applying an axial load to the shaft. The rotation test shows that using gas as the transmission medium can effectively avoid the influence of centrifugal force. The power consumption of the readout circuit is studied, and the results show that the sensor can work continuously for 34.7 days in sleep mode.

Forty-six employees of an industrial bearing plant volunteered to participate in a workplace hypertension program. The purpose of this study was to lower hypertensive employees' blood pressure by having plant supervisors educate the employee in an eight-week hypertension program on his or her high blood pressure. This was done in an effort to aid employees in the management of their blood pressure, as well as to provide a source of emotional support within the plant. Subjects were randomly assigned to an experimental or control group. Supervisors of each hypertensive subject were given educational instruction on high blood pressure and variables related to hypertension. Supervisors also were given specific weekly assignments to convey to their subjects. Pretest and posttest measurements were made on blood pressure and knowledge concerning blood pressure. At the end of the eight-week intervention, a significant decrease in systolic blood pressure was seen in the experimental group with a 16 mm.Hg. drop (p < .05). There was no significant difference (p > .05) between the two groups on diastolic pressures, with both groups dropping to within the guidelines recommended by the American Heart Association (1987). Subjects in the experimental group scored higher on their knowledge of blood pressure than did subjects in the control group (p < .01). The results of this study indicate that a hypertensive educational intervention program may produce positive changes in employee blood pressure responses. / Master of Science

No description available.

Avdelningen för Medicinsk teknik på Akademiska sjukhuset har uppdaterat befintliga kalibreringsprotokoll för Welch Allyn 767 som används som referensmanometer vid kalibrering av blodtrycksmätare. I protokollet ska det enligt ISO 9001 och ISO 13485 ingå att vid varje kalibreringspunkt ange mätosäkerheten.  Rutiner kring detta var inte definierade. En modell för att ta fram mätosäkerhet utformades utifrån standardiserade metoder från “Guide to the expression of uncertainty in measurement” och anpassades för att kunna användas på den medicintekniska avdelningen. En mätmetod för kalibrering togs fram och med modellen beräknades mätosäkerhet för en referensmanometer. Mätosäkerheten med definierad mätmetod blev lägre än den av Welch Allyn specificerade mätosäkerheten på ± 3 mmHg. Felfortplantning från kalibrering till blodtrycksmätning undersöktes. Mätosäkerheten ökade i varje steg, varför avdelningen bör ta fram ett protokoll för hur kalibrering genomförs, och på så sätt förbättra spårbarheten. / The department of Medical Technology at Akademiska sjukhuset has updated their current protocol for calibration for Welch Allyn 767, which serves as a reference manometer for blood pressure meters when being calibrated. According to ISO 9001 and ISO 13485, the protocol has to include a measurement uncertainty for every given point of calibration. The routines regarding this were undefined. A model for retrieving measurement uncertainty was designed using standardized methods from “Guide to the expression of uncertainty in measurement” and was customized to be used at the department of Medical Technology. A method for calibration was created and used to calculate the measurement uncertainty for the reference manometer. This measurement uncertainty was smaller than the one specified by Welch Allyn, which was ± 3 mmHg. Propagation of uncertainty from the calibration to the blood pressure measurement was investigated. The measurement uncertainty increased in every step. Therefore, the department should introduce a protocol for how a calibration is performed, and thereby improve the traceability.

Avdelningen för Medicinsk teknik på Akademiska sjukhuset har uppdaterat befintliga kalibreringsprotokoll för Welch Allyn 767 som används som referensmanometer vid kalibrering av blodtrycksmätare. I protokollet ska det enligt ISO 9001 och ISO 13485 ingå att vid varje kalibreringspunkt ange mätosäkerheten.  Rutiner kring detta var inte definierade. En modell för att ta fram mätosäkerhet utformades utifrån standardiserade metoder från “Guide to the expression of uncertainty in measurement” och anpassades för att kunna användas på den medicintekniska avdelningen. En mätmetod för kalibrering togs fram och med modellen beräknades mätosäkerhet för en referensmanometer. Mätosäkerheten med definierad mätmetod blev lägre än den av Welch Allyn specificerade mätosäkerheten på ± 3 mmHg. Felfortplantning från kalibrering till blodtrycksmätning undersöktes. Mätosäkerheten ökade i varje steg, varför avdelningen bör ta fram ett protokoll för hur kalibrering genomförs, och på så sätt förbättra spårbarheten. / The department of Medical Technology at Akademiska sjukhuset has updated their current protocol for calibration for Welch Allyn 767, which serves as a reference manometer for blood pressure meters when being calibrated. According to ISO 9001 and ISO 13485, the protocol has to include a measurement uncertainty for every given point of calibration. The routines regarding this were undefined. A model for retrieving measurement uncertainty was designed using standardized methods from “Guide to the expression of uncertainty in measurement” and was customized to be used at the department of Medical Technology. A method for calibration was created and used to calculate the measurement uncertainty for the reference manometer. This measurement uncertainty was smaller than the one specified by Welch Allyn, which was ± 3 mmHg. Propagation of uncertainty from the calibration to the blood pressure measurement was investigated. The measurement uncertainty increased in every step. Therefore, the department should introduce a protocol for how a calibration is performed, and thereby improve the traceability.