The aim of strategic group analysis is to find out if clusters of firms that have a similar strategic position exist within an industry or not. In this thesis, by using a conceptual framework that reflects the strategic context, contents and process of construction companies and utilising alternative clustering methods such as traditional cluster analysis, self-organizing maps, and fuzzy C-means technique, a strategic group analysis was conducted for the Turkish construction industry. Results demonstrate that there are three strategic groups among which significant performance differences exist. Self-organising maps provide a visual representation of group composition and help identification of hybrid structures. Fuzzy C-means technique reveals the membership degrees of a firm to each strategic group. It is recommended that real strategic group structure can only be identified by using alternative cluster analysis methods. The positive effect of differentiation strategy on achieving competitive advantage is widely acknowledged in the literature and proved to be valid for the Turkish construction industry as a result of strategic group analysis. In this study, a framework is proposed to model the differentiation process in construction. The relationships between the modes and drivers of differentiation are analyzed by structural equation modeling. The results demonstrate that construction companies can either differentiate on quality or productivity. Project management related factors extensively influence productivity differentiation whereas they influence quality differentiation indirectly. Corporate management related factors only affect quality differentiation. Moreover, resources influence productivity differentiation directly whereas they have an indirect effect on quality differentiation.

The Self-Organizing Map (SOM) is a type of neural network that forms a regular grid of neurons where clusters of neurons represent different classes of targets. The aim of this thesis is to design electromagnetic target classifiers by using the Self-Organizing Map (SOM) type artificial neural networks for dielectric and conducting objects with simple or complex geometries. Design simulations will be realized for perfect dielectric spheres and also for small-scaled aircraft targets modeled by thin conducting wires. The SOM classifiers will be designed by target features extracted from the scattered signals of targets at various aspects by using the Wigner distribution. Noise performance of classifiers will be improved by using slightly noisy input data in SOM training.

The response of geological materials at the scale of meters and the response of buried targets of different shapes and sizes using controlled-source electromagnetic induction (CSEM) is investigated. This dissertation focuses on three topics; i) frac- tal properties on electric conductivity data from near-surface geology and processing techniques for enhancing man-made target responses, ii) non-linear inversion of spa- tiotemporal data using continuation method, and iii) classification of CSEM transient and spatiotemporal data. In the first topic, apparent conductivity profiles and maps were studied to de- termine self-affine properties of the geological noise and the effects of man-made con- ductive metal targets. 2-D Fourier transform and omnidirectional variograms showed that variations in apparent conductivity exhibit self-affinity, corresponding to frac- tional Brownian motion. Self-affinity no longer holds when targets are buried in the near-surface, making feasible the use of spectral methods to determine their pres- ence. The difference between the geology and target responses can be exploited using wavelet decomposition. A series of experiments showed that wavelet filtering is able to separate target responses from the geological background. In the second topic, a continuation-based inversion method approach is adopted, based on path-tracking in model space, to solve the non-linear least squares prob- lem for unexploded ordnance (UXO) data. The model corresponds to a stretched- exponential decay of eddy currents induced in a magnetic spheroid. The fast inversion of actual field multi-receiver CSEM responses of inert, buried ordnance is also shown. Software based on the continuation method could be installed within a multi-receiver CSEM sensor and used for near-real-time UXO decision. In the third topic, unsupervised self-organizing maps (SOM) were adapted for data clustering and classification. The use of self-organizing maps (SOM) for central- loop CSEM transients shows potential capability to perform classification, discrimi- nating background and non-dangerous items (clutter) data from, for instance, unex- ploded ordnance. Implementation of a merge SOM algorithm showed that clustering and classification of spatiotemporal CSEM data is possible. The ability to extract tar- get signals from a background-contaminated pattern is desired to avoid dealing with forward models containing subsurface response or to implement processing algorithm to remove, to some degree, the effects of background response and the target-host interactions.

The extent to which cortical maps may reorganize in adult humans is a significant and topical debate in visual neuroscience. Though there are conflicting findings, evidence from humans and animals indicates that the topography of the visual cortex may change after retinal deafferentation. Remarkably, this reorganization seems to be possible in adults, whose brains are less amenable to plastic change. If adult visual reorganization is legitimate, an understanding of its causes and consequences could be profound considering the millions suffering from age-related visual disorders. This dissertation explores whether visual training may yield a reorganization of sensory maps in the adult visual cortex. It describes research in which patients, diagnosed with age-related macular degeneration (AMD), underwent visual rehabilitation therapy. Functional brain scans and behavioral tests were conducted pre and post training. These interventions generated valuable knowledge regarding whether "reorganized" activity is a true rewiring of feed forward cortical processes or an artifact of attentional feedback. The rehabilitation training produced demonstrable differences in activation patterns along the primary visual cortex (V1), but sparse improvement in the behavioral tests. In contrast, there was significant improvement in fixation tests which assessed oculomotor control. These results suggest that the nature of reorganized activity has more to do with attentional mechanisms than feed forward reorganization. Future investigations could benefit from examining the brain sites that govern visual attention in the frontal and parietal cortices. These areas may have more to do with visual adaptation in AMD patients than V1.

<p>Recent literature has investigated the use of different clustering techniques for analysis of gene expression data. For example, self-organizing maps (SOMs) have been used to identify gene clusters of clear biological relevance in human hematopoietic differentiation and the yeast cell cycle (Tamayo et al., 1999). Hierarchical clustering has also been proposed for identifying clusters of genes that share common roles in cellular processes (Eisen et al., 1998; Michaels et al., 1998; Wen et al., 1998). Systematic evaluation of clustering results is as important as generating the clusters. However, this is a difficult task, which is often overlooked in gene expression studies. Several gene expression studies claim success of the clustering algorithm without showing a validation of complete clusterings, for example Ben-Dor and Yakhini (1999) and Törönen et al. (1999).</p><p>In this dissertation we propose an evaluation approach based on a relative entropy measure that uses additional knowledge about genes (gene annotations) besides the gene expression data. More specifically, we use gene annotations in the form of an enzyme classification hierarchy, to evaluate clusterings. This classification is based on the main chemical reactions that are catalysed by enzymes. Furthermore, we evaluate clusterings with pure statistical measures of cluster validity (compactness and isolation).</p><p>The experiments include applying two types of clustering methods (SOMs and hierarchical clustering) on a data set for which good annotation is available, so that the results can be partly validated from the viewpoint of biological relevance.</p><p>The evaluation of the clusters indicates that clusters obtained from hierarchical average linkage clustering have much higher relative entropy values and lower compactness and isolation compared to SOM clusters. Clusters with high relative entropy often contain enzymes that are involved in the same enzymatic activity. On the other hand, the compactness and isolation measures do not seem to be reliable for evaluation of clustering results.</p>

Change detection is an ability that allows intelligent agents to react to unexpected situations. This mechanism is fundamental in providing more autonomy to robots. It has been used in many different fields including quality control and network intrusion. In the visual domain, however, most research has been confined to stationary cameras and only recently have researchers started to shift to mobile cameras. \ We propose a general framework for building internal spatial models of the visual experiences. These models are used to retrieve expectations about visual inputs which can be compared to the actual observation in order to identify the presence of changes. Our framework leverages the tolerance to small view changes of optic flow and color histogram representations and a self-organizing map to build a compact memory of camera observations. The effectiveness of the approach is demonstrated in a walking simulation, where spatial information and color histograms are combined to detect changes in a room. The location signal allows the algorithm to query the self-organizing map for the expected color histogram and compare it to the current input. Any deviations can be considered changes and are then localized on the input image. Furthermore, we show how detecting a vehicle entering or leaving the camera's lane can be reduced to a change detection problem. This simplifies the problem by removing the need to track or even know about other vehicles. Matching Pursuit is used to learn a compact dictionary to describe the observed experiences. Using this approach, changes are detected when the learned dictionary is unable to reconstruct the current input. The human experiments presented in this dissertation support the idea that humans build statistical models that evolve with experience. We provide evidence that not only does this experience improve people's behavior in 3D environments, but also enables them to detect chromatic changes. Mobile cameras are now part of our everyday lives, ranging from built-in laptop cameras to cell phone cameras. The vision of this research is to enable these devices with change detection mechanisms to solve a large class of problems. Beyond presenting a foundation that effectively detects changes in environments, we also show that the algorithms employed are computationally inexpensive. The practicality of this approach is demonstrated by a partial implementation of the algorithm on commodity hardware such as Android mobile devices. / text

Colloidal particles serve as useful building blocks for materials applications ranging from controlled band-gap materials to rationally designed drug delivery systems. Thus, developing approaches to direct the assembly and disassembly of sub-micron sized particles will be paramount to further advances in materials science engineering. This project focuses on using programmable and reversible binding between oligonucleotide strands to assemble and then disassemble polystyrene colloidal particles. It is shown that DNA-mediated assembly can be reversed at a fixed temperature using secondary oligonucleotide strands to competitively displace the primary strands linking particles together. It was found that 1) titrating the surface density of hybridizing probe strands and 2) adjusting the base length difference between primary and secondary target strands was key to successful isothermal disassembly. In order to titrate the surface density of primary probe-target duplexes, colloidal particles were conjugated with mixtures of probe strands and "diluent" strands in order to minimize the number of DNA linkages between particles. To reduce the steric interference of the diluent strands to hybridization events, diluent strands were clipped with a restriction enzyme in select cases. Kinetics studies revealed that a four to six base-length difference between primary and secondary target strands resulted in extensive competitive hybridization at secondary oligonucleotide concentrations as low as 10 nM. Importantly, it was found that the timing for release of either DNA alone or DNA-conjugated nanoparticles could be tuned through choices in the DNA sequences and concentration. Lastly, competitive hybridization was explored in select studies to drive the "shedding" of PEGylated DNA targets from microspheres to reveal underlying adhesive groups or ligands on the particle surface. Unlike prior work relying on elevated temperatures to melt DNA-linkages, this work presents an important first step towards extending DNA as a reversible assembly tool for physiological applications such as multifunctional drug delivery vehicles programmed to disassemble at targeted tissue sites such as malignant tumors.

Thesis {Ph.D.) -- University of Western Sydney, Nepean, 1998. / Bibliography : p. 328-344.

Thesis (MSc)--Stellenbosch University, 2012. / ENGLISH ABSTRACT: see item for full text / AFRIKAANSE OPSOMMING: sien item vir volteks

Este estudo propõe um modelo híbrido que reúne uma rede neural do tipo SOM (Self-Organizing Map) com uma rede neural do tipo Multicamadas com Retropropagação (BPN: Backpropagation Network). A utilização da rede SOM tem o intuito de segmentar a base de dados em diversos clusters, onde são ressaltadas suas diferenças. A rede BPN é usada para construir um modelo matemático de previsão que descreve a relação entre os indicadores e o valor de fechamento de cada cluster formado na rede SOM. A viabilidade e o percentual de efetividade do modelo proposto são demonstrados através de experimentos de predição de índices utilizados pelo NYSE (New York Stock Exchange). O modelo foi elaborado a partir de uma base de dados composta pelo índice NYSE Composite U.S. 100 no período entre 02 de abril de 2004 a 08 de novembro de 2012. Como variáveis de entrada para as redes neurais, foram utilizados 10 índices: MA_10, BIAS_20, WMS%R_9, K_9, D_9, MTM_10, ROC_10, CCI_24, AR_26, BR_26. Os resultados obtidos com o modelo híbrido proposto se mostraram superiores aos obtidos com modelos convencionais estatísticos. / This study proposes a hybrid model that combines a neural network SOM (Self-Organizing Map) with a neural network with Multilayer Backpropagation (BPN: Backpropagation Network). The SOM aims to segment the database into different clusters, where they highlight their differences. The BPN network is used to build a predictive mathematical model that describes the relationship between the indicators and the closing value of each cluster formed in the SOM. The percentage of viability and effectiveness of the proposed model are demonstrated through experiments predict index used by the NYSE (New York Stock Exchange). The model was developed from a database composed of 100 U.S. NYSE Composite Index in the period from April, 02, 2004 to November, 08, 2012. As input variables for neural networks, we used 10 indices: MA_10, BIAS_20, WMS%R_9, K_9, D_9, MTM_10, ROC_10, CCI_24, AR_26, BR_26. Results obtained with the proposed hybrid model were higher than those obtained with conventional statisticals techniques.