The primary purpose of this dissertation is to study the necessity of genre consideration in the three important sermon-making process--exegetical, theological, and homiletical--and propose a holistic preaching methodology for the lament psalms with genre-sensitivity. Chapter 1 discusses the definitional nature, criteria, and communicational function of genre and examines the current defective and deficient preaching method with genre-sensitivity, and also indicates the lack of concern of the lament psalms in biblical preaching. Chapter 2 examines a holistic exegetical method for preaching a lament psalm by emphasizing the necessity of the analysis and appreciation of the mood of the text based upon the interlocking nature of genre-based textual elements (the message, medium, and mood of the text) and genre-based contextual element (the purpose of the text). This chapter provides a step-by step holistic procedure for preaching a lament psalm with genre-sensitivity. Chapter 3 investigates the necessity of genre consideration in the theological process. This section emphasizes that consideration of the genre characteristics is an essential process for discerning a timeless theological implication and communicational impact of a lament psalm. This chapter suggests a step-by-step holistic theological procedure for preaching a lament psalm with genre-sensitivity. Chapter 4 discusses the necessity of a genre-sensitive homiletical method that reflects the genre-based essentials into the sermon-making process. This section emphasizes the necessity of a holistic integration of the genre-sensitive homiletical components for preaching a lament psalm. This chapter presents a step-by-step procedure for a holistic homiletical method for preaching a lament psalm with genre-sensitivity. Chapter 5 analyzes Psalm 31 as a case study of a genre-sensitive methodology for preaching a lament psalm proposed in the previous chapters. This chapter elaborates and verifies the twelve steps for preaching a lament psalm with genre-sensitivity. Chapter 6 concludes that biblical preachers need to preach the lament psalms with genre-sensitivity by honoring the message, medium, and mood of the text throughout the entire sermon-making process in pursuit of honoring the authority of the Scripture and remodeling the relevance of the biblical communication.

A clinical study was performed in order to determine if healthy test subjects can differentiate between adjacent and separated pairs of vertebrae in the lumbar spine. The variable of interest was number of correctly specied pairs of vertebrae. The test subjects were evaluated in terms of sensitivity and specicity of this test. Bootstrap resampling was applied in the data analysis. The results clearly indicated that the test subjects in this study were able to successfully determine whether a pair of adjacent or separated vertebrae was tested during the procedure.

Motivation: Abdominal obesity (hereafter referred to as "obesity") is becoming the biggest "global epidemic" of our modern times. It is associated with a range of diseases, including cardiovascular diseases and hypertension. Recent research showed that an increase in sympathetic activity is of central importance in the pathogenesis of obesity-related diseases. Increased leptin levels and impaired baroreflex sensitivity have both been independently associated with abdominal obesity and increased sympathetic activity. A perception of poorer health may also contribute to the physiological characteristics of obesity-related diseases. A lack of data regarding sympathetic activity, leptin levels, baroreflex sensitivity and perception of health in Africans, serves as a motivation for conducting this study. Objective: To investigate the contributions of leptin levels, baroreflex sensitivity and perception of health data to increased sympathetic activity in lean and obese African women from South Africa. Methodology: The manuscript presented in Chapter 2 made use of the data obtained in the POWIRS (Profiles of Obese Women with the Insulin Resistance Syndrome) study. A group of 102 urbanized African women, living in the North-West Province of South Africa, was recruited according to body mass indexes. Only 85 subjects were included for analysis due to incomplete datasets. For this study, subjects were divided into lean and obese groups according to their waist circumferences. Anthropometric measurements were done according to standardized methods. Resting cardiovascular measurements were obtained from Finometer observations. Resting, fasting levels of leptin were calculated after radioimmunoassay analyses. Subjective perception of health was determined by means of the 28-item General Health Questionnaire. Comparisons between the groups were done using analysis of covariance (ANCOVA) whilst adjusting for cardiovascular risk factors (age. smoking, alcohol consumption and physical activity). Correlation coefficients were determined to indicate any associations between leptin, baroreflex sensitivity and perception of health with sympathetic activity (represented by heart rate) and other cardiovascular variables. The study was approved by the Ethics committee of the North-West University and all the subjects gave informed consent in writing. The reader is referred to the Methods section in Chapter 2 for a more detailed description of the subjects, study design and analytical procedures used in this dissertation. Results and conclusion: Results from this study indicate that obese African women, compared to lean African women, were older, reported higher physical activity, and exhibited higher diastolic and mean blood pressure, heart rate, cardiac output, arterial compliance, leptin and hypertension prevalence rate values. In lean African women social dysfunction was positively associated with diastolic and mean blood pressure and arterial resistance, and negatively with arterial compliance. In obese African women baroreflex sensitivity was negatively associated with diastolic blood pressure, which could be an indication of impaired baroreflex sensitivity. In this obese group a perception of social dysfunction was associated with decreased heart rate. Although leptin and heart rate were significantly higher in the obese Africans, no significant correlations existed between these variables to reflect leptin's enhancement of sympathetic activity. However, leptin correlated weakly but positively with cardiac output (p = 0.054, r = 0.32). In conclusion, baroreflex sensitivity (although similar between groups) and leptin seem to contribute to blood pressure and thus hypertension in obese African women, possibly through increased sympathetic activity and volume loading. A perception of poorer health, especially a perception of social dysfunction, could possibly contribute to this image. / Thesis (M.Sc. (Physiology))--North-West University, Potchefstroom Campus, 2007.

Volterra Series (VS) is often used in the analysis of mildly nonlinear circuits. In this approach, nonlinear circuit analysis is converted into the analysis of a series of linear circuits. The main benefit of this approach is that linear circuit analysis is well established and direct frequency domain analysis of a nonlinear circuit becomes possible. Sensitivity analysis is useful in comparing the quality of two designs and the evaluation of gradient, Jacobian or Hessian matrices, in analog Computer Aided Design. This thesis presents, for the first time, the sensitivity analysis of mildly nonlinear circuits in the frequency domain as an extension of the VS approach. To overcome efficiency limitation due to multiple mixing effects, Nonlinear Transfer Matrix (NTM) is introduced. It is the first explicit analytical representation of the complicated multiple mixing effects. The application of NTM in sensitivity analysis is capable of two orders of magnitude speedup. Per-element distortion decomposition determines the contribution towards the total distortion from an individual nonlinearity. It is useful in design optimization, symbolic simplification and nonlinear model reduction. In this thesis, a numerical distortion decomposition technique is introduced which combines the insight of traditional symbolic analysis with the numerical advantages of SPICE like simulators. The use of NTM leads to an efficient implementation. The proposed method greatly extends the size of the circuit and the complexity of the transistor model over what previous approaches could handle. For example, industry standard compact model, such as BSIM3V3 [35] was used for the first time in distortion analysis. The decomposition can be achieved at device, transistor and block level, all with device level accuracy. The theories have been implemented in a computer program and validated on examples. The proposed methods will leverage the performance of present VS based distortion analysis to the next level.

This thesis examines the validity of polyvagal theory as a model of normal socio-emotional responding (Porges, 1995, 2001, 2003a). Polyvagal theory makes several claims, and to date many of its predictions lack empirical testing. In the current research, five main hypotheses stemming from polyvagal theory were identified and tested using healthy participants. The initial empirical study examined the influence of laboratory stressors on autonomic function. The findings revealed that social evaluative threat increases activation of the sympathetic nervous system more than a virtual reality maze, and that arousal remains elevated for longer during anticipation of social evaluative threat in comparison to recovery from social evaluative threat. The second study investigated the effects of emotion regulation strategies on autonomic function, and highlighted the effectiveness of two meditation practices in reducing defensive physiological arousal and increasing subjective positive emotion. These studies were followed with a set of studies designed to evaluate the effects of defensive physiological arousal on socio-emotional functioning, as a direct test of polyvagal theory. The first study examined the effects of a laboratory stressor on facial expressivity, revealing that social evaluative threat had little impact on expressive regulation. A second study investigated the effects of a laboratory stressor on emotional sensitivity and spontaneous facial mimicry. Some limited support was found for polyvagal theory, although neither emotional sensitivity nor facial mimicry was significantly affected by laboratory stress. A final empirical study investigated the effects of a laboratory stressor on affiliation tendencies. The laboratory stressor did not influence participants’ willingness to spend time with others, however the experiment did reveal significant relationships between markers of social safeness and affiliation. The overall conclusion of this thesis is that polyvagal may not be a representative model of socio-emotional functioning in healthy participants. The implications of these findings are discussed in relation to the validity of polyvagal theory as a universal model of socio-emotional responding.

Based on existing theories of personality and socio-emotional functioning (e.g. Clark, 2005; Lynch, Hempel & Clark, in press) a new model is proposed and tested. The model hypothesises that (i) temperament (reward and threat sensitivity) and childhood invalidation predict problems with interpersonal functioning, (ii) this effect is mediated by self-regulatory capacity; where self-regulatory capacity comprises self-control (ranging from emotional over-control to emotional under-control) and flexible control and (iii) self-regulatory capacity itself has a quadratic relationship with interpersonal functioning. A UK community sample (n= 512) completed a self-report survey, measuring each of the aforementioned latent variables. Structural equation modelling (SEM) was used to determine the goodness-of-fit of this and variations of this model. SEM identified that a non-mediation model provided the best fit (χ²=49.403, p< 0.001; CFI=0.98; RMSEA=0.056). Good-fit was obtained for a model including flexible control as a partial mediator (χ²=269.06, p< 0.001; CFI=0.956; RMSEA=0.081) and adequate-fit for a model including over-control as a partial mediator (χ²= 91.744, p < 0.001, CFI=0.932; RMSEA= 0.096). Correlation analyses suggested that over-control and under-control correlated positively with interpersonal problems. Results from SEM provided promising initial evidence for the mediating role of self-regulatory capacity, particularly for the flexible control component. Correlation analyses provided support for the non-linear relationship between self-regulatory capacity and interpersonal functioning, whereby extreme over-control or extreme under-control is associated with interpersonal problems. Findings have implications for identifying mechanisms of change for therapeutic approaches to emotion dysregulation and for understanding the over-controlled population, which has previously been overlooked.

The thesis aim was to increase understanding of interpersonal antecedents and consequences of rumination, defined as ‘repetitive and passive thinking about one’s symptoms of depression and the possible causes and consequences of those symptoms’ (Nolen-Hoeksema, 2004, p.107). As a proof-of-principle study, rumination predicted diminished relationship satisfaction, three months later, in a sample of remitted depressed adults (N = 57). In the next study, rumination was associated with a maladaptive submissive interpersonal style and rejection sensitivity, controlling for depressive symptoms, other interpersonal styles and gender, in a different sample (N = 103 currently depressed, previously depressed and never depressed adults). Subsequent chapters incorporated a second assessment point of data from this same sample. Longitudinal analyses were undertaken to investigate; a) do rumination and depressogenic interpersonal factors predict future depression?; b) does rumination prospectively predict increased rejection sensitivity and submissive interpersonal behaviours, and, vice-versa, do these interpersonal factors predict increased rumination?; c) does rumination prospectively predict poor social adjustment and interpersonal stress? Consistent with previous findings, Time 1 rumination predicted increased depression six months later. Unexpectedly, the effect of rumination on future depression was mediated by its relationship with the submissive interpersonal style. Partially consistent with the stated predictions, Time 1 rejection sensitivity (but not the submissive interpersonal style) prospectively predicted increased rumination, but rumination did not predict rejection sensitivity or the submissive interpersonal style. As predicted, rumination prospectively predicted increased chronic interpersonal stress and poor social adjustment (but not acute interpersonal stress). In a final study, rumination was manipulated via an applied intervention (concreteness training, CT), within the context of a randomized controlled trial (N = 79 clinically depressed adults). Analyses compared the change in social adjustment and submissive interpersonal behaviour reported in the CT condition compared to a treatment as usual (TAU) condition. There was a significantly greater reduction in rumination in the CT compared to TAU condition, p < .05. Moreover, the reduction in submissive interpersonal behaviours was significantly greater in the CT compared to TAU condition, p < .05. The change in social adjustment was not greater in the CT compared to TAU condition. Thus, a psychological intervention which reduces rumination decreased maladaptive submissive interpersonal behaviour. The implications of the findings are discussed in relation to theory of rumination and interpersonal theories of depression.

Area sensitivity of North American grassland birds is a significant conservation concern; yet, its causes are not known. I used point count data from 20 tall-grass prairie patches in Southern Manitoba to assess the relative importance of patch size, edge proximity, and landscape composition on the densities and species richness of grassland songbirds. The degree to which the landscape surrounding point count plots was open, as opposed to forested or urban, had a positive effect on species richness and the densities of most focal species, and was more important than patch size, edge proximity, or habitat amount. These results suggest that landscape openness, not patch size (with which it is usually correlated) drives area sensitivity. Small grassland patches embedded in open landscapes are less susceptible to area sensitivity and may be of high conservation value for grassland birds. / February 2017

<b>Introduction</b>: Kinesiology-style manual muscle testing (kMMT) is a non-invasive assessment method used by various types of practitioners to detect a wide range of target conditions. It is distinctly different from the muscle testing performed in orthopaedic/neurological settings and from Applied kinesiology. Despite being estimated to be used by over 1 million people worldwide, the usefulness of kMMT has not yet been established. The aim of this thesis was to assess the validity of kMMT by examining its accuracy and precision. <b>Methods</b>: A series of 5 diagnostic test accuracy studies were undertaken. In the first study, the index test was kMMT, and the target condition was deceit in verbal statements spoken by Test Patients (TPs). The comparator reference standard was a true gold standard: the actual verity of the spoken statement. The outcomes of the muscle tests were interpreted consistently: a weak result indicated a Lie and a strong result indicated a Truth. A secondary index test was included as a comparator: Intuition, where Practitioners used intuition (without using kMMT) to ascertain if a Lie or Truth was spoken. Forty-eight Practitioners were recruited and paired with 48 unique kMMT-naïve TPs. Each Pair performed 60 kMMTs broken up into 6 blocks of 10, which alternated with blocks of 10 Intuitions. For each Pair, an overall percent correct was calculated for both kMMT and Intuition, and their means were compared. Also calculated for both tests were sensitivity, specificity, positive predictive value and negative predictive value. The second study was a replication of the first, using a sample size of 20 Pairs and a less complex procedure. In the third study, grip strength dynamometry replaced kMMT as the primary index test. In the fourth study, the reproducibility and repeatability of kMMT were examined. In the final study, TPs were presented with emotionally-arousing stimuli in addition to the affect-neutral stimuli used in previous studies, to assess if stimuli valence impacted kMMT accuracy. <b>Results</b>: Throughout this series of studies, mean kMMT accuracies (95% Confidence Intervals; CIs) ranged from 0.594 (0.541 – 0.647) to 0.659 (0.623 - 0.695) and mean Intuition accuracies, from 0.481 (0.456 - 0.506) to 0.526 (0.488 - 0.564). In all studies, mean kMMT accuracies were found to be significantly different from mean Intuition accuracies (p ≤ 0.01), and from Chance (p < 0.01). On the other hand, no difference was found between grip strength following False statements compared to grip strength following True statements (p = 0.61). In addition, the Practitioner-TP complex accounted for 57% of the variation in kMMT accuracy, with 43% unaccounted for. Also, there was no difference in the mean kMMT accuracy when using emotionally-arousing stimuli compared to when using affect-neutral stimuli (p = 0.35). Mean sensitivities (95% CI) ranged from 0.503 (0.421 - 0.584) to 0.659 (0.612 - 0.706) while mean specificities (95% CI) ranged from 0.638 (0.430 - 0.486) to 0.685 (0.616 - 0.754). Finally, while a number of participant characteristic seemed to influence kMMT accuracy during one study or another, no one specific characteristic was found to influence kMMT accuracy consistently (i.e. across the series of studies). <b>Discussion</b>: This series of studies has shown that kMMT can be investigated using rigorous evidence-based health care methods. Furthermore, for distinguishing lies from truths, kMMT has repeatedly been found to be significantly more accurate than both Intuition and Chance. Practitioners appear to be an integral part of the kMMT dynamic because when replaced by a mechanical device (i.e. a grip strength dynamometer), distinguishing Lies from Truth was not possible. In addition, since specificities seemed to be greater than sensitivities, Truths may have been easier to detect than Lies. A limitation of this series of studies is that I have a potential conflict of interest, in that I am a practitioner of kMMT who gets paid to perform kMMT. Another limitation is these results are not generalisable to other applications of kMMT, such as its use in other paradigms or using muscles other than the deltoid. Also, these results suggest that kMMT may be about 60&percnt; accurate, which is statistically different from Intuition and Chance; however it has not been established if 60&percnt; correct is "good enough" in a clinical context. As such, further research is needed to assess its clinical utility, such as randomised controlled trials investigating the effectiveness of whole kMMT technique systems. Also, future investigators may want to explore what factors, such as specific Practitioner and TP characteristics, influence kMMT accuracy, and to investigate the validity of using kMMT to detect other target conditions, using other reference standards and muscles other than the deltoid. <b>Summary</b>: This series of diagnostic test accuracy studies has found that kMMT can be investigated using rigorous methods, and that kMMT used to distinguish Lies from Truths is significantly more accurate that both Intuition and Chance. Further research is needed to assess kMMT’s clinical utility.

The term sedentary refers to a distinct class of activities which involve sitting or reclining and which do not cause an increase in energy expenditure above resting levels. Observational studies have reported positive associations between both sedentary time and the number of hours spent sitting per day, with risk for a number of health outcomes that are independent of moderate to vigorous physical activity (MVPA). The total time spent sitting can be amassed in different patterns (long and short bouts) and different types (watching TV, driving, working at a computer) that may have differential associations with health outcomes as well as different confounders that have yet to be properly explored. Further, limitations in current measures used to quantify sedentary behaviour and the possibility of residual confounding, mean that it is unclear whether the posture of sitting itself represents a risk to health or whether sitting is actually a proxy for low energy expenditure. This thesis aimed to examine; the associations between five separate sitting types with health risk, the prevalence of sitting behaviour in England, and the biological mechanisms which might underpin the observed negative health consequences of sitting. Using data from the Whitehall II cohort study the first four studies of this thesis examined prospective associations between sitting at work, TV viewing, non-TV leisure time sitting, total leisure time sitting (TV and non-TV leisure sitting combined) and total sitting from work and leisure, with four health outcomes; mortality, cardiovascular disease, type II diabetes and obesity. No association between any of the sitting indicators with risk for mortality or incident cardiovascular disease was found. TV viewing and total sitting were associated with an increase in risk for type II diabetes following adjustment for sociodemographic covariates and MVPA, but were attenuated following further adjustment for body mass index. None of the five sitting indicators were associated with incident obesity but being obese prior to the measurement of sitting was associated with the number of reported hours of daily TV viewing. The final study of this thesis examined the acute effect of sustained versus interrupted sitting on glucose and insulin metabolism. Interrupting sitting with repeated short bouts of light intensity walking significantly improved insulin sensitivity while repeated short bouts of standing did not. Sitting is a prevalent behaviour in English adults and varies by socio-demographic characteristics. Previously reported associations between sitting time and health risk may be confounded by light intensity physical activity and obesity. The absence of an effect of repeated standing bouts (a change in posture without a change in energy expenditure) suggests that promoting reductions in sitting without also promoting increases in movement are not likely to lead to improvements in metabolic health. New measures of sedentary behaviour are required that can be used in population studies, and can discriminate between the posture of sitting, standing and very low levels of physical activity of a light intensity. This would permit further studies that are needed to clarify the precise nature of the association between sitting and health.