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Fonctions du facteur de transcription SCL dans les cellules souches et les progéniteurs hématopoïétiquesLacombe, Julie January 2008 (has links)
Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal.
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Caracterização aerodinâmica de edifícios altos com planta em formato de “V” através de análise espectralVogado, Monique Wesz January 2018 (has links)
Nas últimas décadas, tem-se observado uma forte tendência de edificações cada vez mais altas, esbeltas e flexíveis, o que exigiu novas considerações no cálculo estrutural de edifícios, tornando a ação do vento um elemento de grande relevância nos projetos. Além disso, o denso agrupamento de edificações nos centros de grandes cidades adicionou uma variável para um fenômeno que já era complexo: devido à proximidade, um edifício passa a influenciar o campo aerodinâmico de outros, podendo provocar grandes alterações nas pressões, além de fenômenos dinâmicos difíceis de determinar por métodos analíticos. Instruções normativas, em geral, limitam-se a prédios altos com padrões arquitetônicos regulares, afastando-se da realidade dos projetos construídos na prática, que vêm exibindo geometrias cada vez mais complexas e não convencionais. Este cenário justifica a realização de extensos estudos dentro do tema em questão, a fim de que se obtenha uma melhor compreensão dos fenômenos dinâmicos envolvidos e uma orientação mais abrangente na etapa de pré-dimensionamento da estrutura. Neste contexto, a proposta desta pesquisa consiste em dois estudos de caso, de edifícios construídos no Brasil e ensaiados em túnel de vento, que possuem uma geometria similar (em formato de “V”), mas com dimensões e detalhes arquitetônicos distintos. O objetivo é o de promover uma caracterização aerodinâmica, avaliando os carregamentos atuando global e localmente, tanto para o modelo considerado isolado quanto incluindo as condições de vizinhança. Além das ações, estudou-se o espectro do vento que se aproxima, e determinou-se as funções de admitância aerodinâmica correspondentes. Em ambos os edifícios, verificou-se que a incidência do vento aproximadamente perpendicular a uma das abas corresponde a uma direção crítica em termos de efeitos dinâmicos: os espectros dos carregamentos globais se mostraram muito similares, apresentando picos pronunciados que indicam a possibilidade de desprendimento cadenciado de vórtices; as funções de admitância aerodinâmica também evidenciaram um formato muito semelhante. O estudo em questão oferece um meio de validação para estudos futuros que utilizem modelos de ensaio simplificados, além de servir de referência para uma possível revisão da norma brasileira NBR 6123/1988 – Forças devidas ao vento em edificações, contribuindo com os avanços do conhecimento relativo a efeitos dinâmicos do vento em edifícios altos e irregulares. / In the last decades we observed a strong trend in constructing buildings increasingly tall, slender and flexible, which has asked for new consideration in the structural calculus of buildings, making the wind a relevant element in the design procedures. The grouping of buildings downtown in big cities has added another variable to an already complex phenomenon: due to the proximity, a building influences in the aerodynamic field of others, leading to pressure modifications and dynamic effects hard to determine by analytical methods. Instruction codes, in general, are limited to regular tall buildings, in contrast to the reality of projects built in practice, which have been exhibiting architectonic patterns increasingly complex and unconventional. This scenario justifies extensive studies among aerodynamic of irregular tall buildings, with the purpose of acquiring a better comprehension regarding the dynamic phenomena involved and a more accurate direction on the pre-design phase. In this context, the proposal of this research consists of two case studies about buildings constructed in Brazil and tested in wind tunnel, which have a similar geometry (V-shaped) but different dimensions and architectonic details. The objective is to promote a complete aerodynamic characterization, assessing the loads acting as a whole and also locally, with both isolated and interference conditions. Besides the action, the velocity spectrum of the approaching wind and the corresponding aerodynamic admittance were studied. Either case, it was verified that the wind incidence nearly perpendicular to one of the frontal facades is a critical direction from the perspective of dynamic effects: the spectra of global loads were very similar, with a peak emerging on the graphs, which indicate the possibility of vortex shedding; the admittance function also showed a very close format. This study offers an instrument of validation for future researches that use simplified test models, besides to fit as a reference to a possible revision of the Brazilian code NBR 6123/1988 – Wind load on building structures, contributing to the knowledge advances regarding dynamic effects on irregular tall buildings.
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Structural relationship between shape, shell and core: an alternative for high-rise housing.January 2009 (has links)
Lee Lai Wai, Angela. / "Architecture Department, Chinese University of Hong Kong, Master of Architecture Programme 2008-2009, design report." / Includes bibliographical references (leaf [80]). / Chapter 1 --- Geometrical Studies --- p.5 / Chapter 1.1 --- Previous Attempts --- p.6 / Chapter 1.2 --- "Shape, Shell and Core" --- p.12 / Definitions --- p.13 / Transformation --- p.16 / Interpretation --- p.22 / Manipulation --- p.29 / Variations --- p.34 / Chapter 2 --- Architectural Studies --- p.39 / Chapter 2.1 --- Demonstration --- p.41 / Chapter 2.2 --- Explorations --- p.49 / Chapter 3 --- Housing Design --- p.60
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Fonctions du facteur de transcription SCL dans les cellules souches et les progéniteurs hématopoïétiquesLacombe, Julie January 2008 (has links)
Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal
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Caracterização aerodinâmica de edifícios altos com planta em formato de “V” através de análise espectralVogado, Monique Wesz January 2018 (has links)
Nas últimas décadas, tem-se observado uma forte tendência de edificações cada vez mais altas, esbeltas e flexíveis, o que exigiu novas considerações no cálculo estrutural de edifícios, tornando a ação do vento um elemento de grande relevância nos projetos. Além disso, o denso agrupamento de edificações nos centros de grandes cidades adicionou uma variável para um fenômeno que já era complexo: devido à proximidade, um edifício passa a influenciar o campo aerodinâmico de outros, podendo provocar grandes alterações nas pressões, além de fenômenos dinâmicos difíceis de determinar por métodos analíticos. Instruções normativas, em geral, limitam-se a prédios altos com padrões arquitetônicos regulares, afastando-se da realidade dos projetos construídos na prática, que vêm exibindo geometrias cada vez mais complexas e não convencionais. Este cenário justifica a realização de extensos estudos dentro do tema em questão, a fim de que se obtenha uma melhor compreensão dos fenômenos dinâmicos envolvidos e uma orientação mais abrangente na etapa de pré-dimensionamento da estrutura. Neste contexto, a proposta desta pesquisa consiste em dois estudos de caso, de edifícios construídos no Brasil e ensaiados em túnel de vento, que possuem uma geometria similar (em formato de “V”), mas com dimensões e detalhes arquitetônicos distintos. O objetivo é o de promover uma caracterização aerodinâmica, avaliando os carregamentos atuando global e localmente, tanto para o modelo considerado isolado quanto incluindo as condições de vizinhança. Além das ações, estudou-se o espectro do vento que se aproxima, e determinou-se as funções de admitância aerodinâmica correspondentes. Em ambos os edifícios, verificou-se que a incidência do vento aproximadamente perpendicular a uma das abas corresponde a uma direção crítica em termos de efeitos dinâmicos: os espectros dos carregamentos globais se mostraram muito similares, apresentando picos pronunciados que indicam a possibilidade de desprendimento cadenciado de vórtices; as funções de admitância aerodinâmica também evidenciaram um formato muito semelhante. O estudo em questão oferece um meio de validação para estudos futuros que utilizem modelos de ensaio simplificados, além de servir de referência para uma possível revisão da norma brasileira NBR 6123/1988 – Forças devidas ao vento em edificações, contribuindo com os avanços do conhecimento relativo a efeitos dinâmicos do vento em edifícios altos e irregulares. / In the last decades we observed a strong trend in constructing buildings increasingly tall, slender and flexible, which has asked for new consideration in the structural calculus of buildings, making the wind a relevant element in the design procedures. The grouping of buildings downtown in big cities has added another variable to an already complex phenomenon: due to the proximity, a building influences in the aerodynamic field of others, leading to pressure modifications and dynamic effects hard to determine by analytical methods. Instruction codes, in general, are limited to regular tall buildings, in contrast to the reality of projects built in practice, which have been exhibiting architectonic patterns increasingly complex and unconventional. This scenario justifies extensive studies among aerodynamic of irregular tall buildings, with the purpose of acquiring a better comprehension regarding the dynamic phenomena involved and a more accurate direction on the pre-design phase. In this context, the proposal of this research consists of two case studies about buildings constructed in Brazil and tested in wind tunnel, which have a similar geometry (V-shaped) but different dimensions and architectonic details. The objective is to promote a complete aerodynamic characterization, assessing the loads acting as a whole and also locally, with both isolated and interference conditions. Besides the action, the velocity spectrum of the approaching wind and the corresponding aerodynamic admittance were studied. Either case, it was verified that the wind incidence nearly perpendicular to one of the frontal facades is a critical direction from the perspective of dynamic effects: the spectra of global loads were very similar, with a peak emerging on the graphs, which indicate the possibility of vortex shedding; the admittance function also showed a very close format. This study offers an instrument of validation for future researches that use simplified test models, besides to fit as a reference to a possible revision of the Brazilian code NBR 6123/1988 – Wind load on building structures, contributing to the knowledge advances regarding dynamic effects on irregular tall buildings.
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Desempenho vegetativo e produtivo de macieiras Fuji-kiku-8® e Maxigala em diferentes sistemas de condução em Vacaria, RS / The vegetative and productive performance of Fuji-kiku-8® & Maxigala apple trees in different training systems at Vacaria, RSSander, Guilherme Fontanella 15 April 2015 (has links)
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Previous issue date: 2015-04-15 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Nowadays Brazil is self sustaining in apple. The production is located in
micro regions in Southern Brazil, in Santa Catarina and Rio Grande do
Sul State. The technology and innovation need to be allied of the
technicians and growers, responsible for the nacional production. The
decision of which training system that will be used, it is one of the
decisions that needs to do at planning to plant a new orchard. Is there so
many training systems around the world. The choosed system wills
interfer directlly in the profitability of the orchard. Nationally, the
traditional system used is central leader system, with some changes,
depending on the region that it is installed. With those informations, the
aim of this study was evaluate different training systems in trials that
combine the two most growed cultivars, Gala and Fuji, combined with
the two most used rootstocks, M.9 and Marubakaido with interstem of
M.9. The training systems evaluated were Vertical Axis, Tall Spindle
and Solaxe at Vacaria-RS. The study concludes that Kiku-8®‟, grafted
on M.9 tends to be a bi-annual bearing in all systems, the same cultivar
was more vigorous when grafted on Marubakaido‟ trained in Vertical
Axis. Maxi Gala‟ showed more vigour when trained in Vertical Axis in
both rootstocks. All systems did not have effect in fruit quality
parameters, like total soluble solids, flesh firmness and fruit size. It is
necessary more labor hours Solaxe System in the most part of the
combinations.The choice of which training system is the best to use,
needs to be embased with data of more years of study / O Brasil é autossustentável em maçãs. A produção está concentrada em
micro regiões no Sul do Brasil, nos estados de Santa Catarina e Rio
Grande do Sul. A tecnologia e inovação devem ser aliadas dos técnicos
e produtores responsáveis pela produção nacional. A decisão de qual
sistema de condução é um dos intens a ser planejados antes mesmo da
implantação do pomar. Diversos são os sistemas de condução existentes,
existindo diferentes preferências nas diversas regiões produtoras ao
redor do mundo. O sistema de condução escolhido vai inferir
diretamente na rentabilidade do pomar. Nacionalmente o sistema de
condução tradicional é em líder central, variando sua forma conforme
local e tecnologia empregada. A partir dessas considerações objetivouse
nesse trabalho avaliar diferentes sistemas de condução que utilizam
líder central, em experimentos combinados com as cultivares mais
produzidas no país, Gala e Fuji e com dois dos portaenxertos, M.9 e
Marubakaido com interenxerto de M.9. Os sistemas de condução são o
Vertical Axis, Solaxe e Tall Spindle, no município de Vacaria (RS).
Pode-se concluir neste estudo que Kiku-8®‟ enxertado sobre M.9
mostra tendência a alternância de produção em todos os sistemas de
condução, a mesma foi mais vigorosa quando enxertada sobre
Marubakaido‟ e conduzida em Vertical Axis. Para a Maxi Gala‟
também o sistema Vetical Axis foi o qu mais induziu vigor nos dois
portaenxertos utilizados. Os sistemas de condução não interferem nos
fatores de qualidade de frutos como teor de sólidos solúveis, firmeza de polpa e tamanho de fruto. É necessário maior número de horas de mãode- obra no sistema Solaxe na maior parte das combinaçõe. A decisão para seleção de sistemas de condução terá que ser feita com base em resultados de mais safras
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The finite element method applied to the analysis of tall structural codes. The development of compatible, self equilibriating and hybrid finite elements, and their application to 'plane shear wall' and 'core' problems of the type encountered in modern tall buildings.Boot, John C. January 1976 (has links)
No description available.
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Nitrogen source and timing effect on carbohydrate status of bermudagrass and tall fescueGoldsby, Anthony Lee January 1900 (has links)
Master of Science / Department of Horticulture, Forestry, and Recreation Resources / Steven J. Keeley / Non-structural carbohydrates (NSC) are important for plant health and recovery from stress. Controlled-release N sources may moderate turfgrass vegetative growth, thereby maximizing NSC levels. Three studies were conducted to determine the effect of N source/timing on NSC levels, turfgrass visual quality, and color of ‘Midlawn’ bermudagrass and turf-type tall fescue. Additionally, the effect on low temperature tolerance of bermudagrass and brown patch incidence on tall fescue was investigated. Nitrogen sources included two polymer-coated ureas (PCU), a polymer-sulfur coated urea (SCU) and urea formaldehyde (UF). Total annual N was applied in either late summer or spring for bermudagrass, and either late summer or split between late summer and spring for tall fescue. Urea, applied at traditional timings, was a control in all studies. NSC status was determined at regular intervals by extracting two cores from each plot, defoliating, and measuring regrowth in a dark growth chamber. Turfgrass color, visual quality and brown patch incidence were rated monthly during the growing season. Bermudagrass low temperature tolerance was evaluated by subjecting plugs to a freezing regime and evaluating regrowth. Over the 2-yr study, N source did not have a significant effect on bermudagrass or tall fescue NSC levels, color, or visual quality. Timing of application, by contrast, did have a significant impact. For bermudagrass, August-applied N resulted in higher overall NSC levels and improved fall color. For tall fescue, split Sept/March applications improved color; but split Sept/ May applications reduced NSC compared to a single Sept application. Brown patch incidence was unaffected by N source or timing, though disease pressure was low. Timing of PCU application did not affect low temperature tolerance of bermudagrass, but PCU improved low temperature survival compared to urea.
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Impact of deep building foundations on coastal groundwater flow systemsDing, Guoping, 丁國平 January 2006 (has links)
published_or_final_version / abstract / Earth Sciences / Doctoral / Doctor of Philosophy
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EFFECT OF ERGOT ALKALOIDS ON BOVINE FOREGUT VASCULATURE, NUTRIENT ABSORPTION, AND EPITHELIAL BARRIER FUNCTIONFoote, Andrew P 01 January 2013 (has links)
Ergot alkaloids present in endophyte-infected (E+) tall fescue are thought to be the causative agent of fescue toxicosis, a syndrome affecting cattle in the eastern United States. Many of the observed signs of fescue toxicosis are thought to be attributed to peripheral vasoconstriction; however, there are data indicating that ergot alkaloids can alter blood flow to the gut. An experiment was conducted using right ruminal artery and vein collected from heifers shortly after slaughter. Vessels were mounted in a multi-myograph to determine the vasoconstrictive potentials of ergot alkaloids present in E+ tall fescue. Results indicated ergot alkaloids have the potential to induce vasoconstriction of foregut vasculature. A second experiment was conducted to determine if the additional ergot alkaloids present in E+ tall fescue increase the vasoconstrictive response above that of ergovaline. Results indicated that ergovaline is the main alkaloid responsible for vasoconstriction in bovine vessels. A third study was performed to determine the effect of ergot alkaloids on ruminal epithelial blood flow in the washed rumen of steers exposed to E+ or endophyte-free (E-) tall fescue seed. Steers were dosed with seed followed by a washed rumen experiment with differing levels of ergovaline incubated in the rumen. Results indicated that E+ tall fescue seed treatment reduced ruminal epithelial blood flow. Additionally, incubating ergovaline in the rumen during the washed rumen further decreased epithelial blood flow and volatile fatty acid (VFA) absorption. A final study was conducted to determine the acute effects of ergot alkaloids on isolated rumen epithelial absorptive and barrier functions and the potential for ruminal ergovaline absorption. Results indicate that acute exposure to ergot alkaloids does not alter the absorptive or barrier function of rumen epithelium and ergovaline is absorbed from the rumen. Data from this series of experiments have shown that ergot alkaloids from E+ tall fescue can induce vasoconstriction of blood vessels in the foregut of cattle, reduce blood flow to the rumen epithelium, and decrease VFA absorption. The decrease in nutrient absorption could contribute to the observed symptoms of fescue toxicosis, including depressed growth rates and general unthriftiness.
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