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Zugl.: Birmingham, Aston Univ., Diss., 2009

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The general purpose of the study was to describe the present status of personnel administrators in selected Ohio school districts.

Thesis (Ph. D.)--University of Chicago, 1943. / Lithoprinted. Bibliography: p. 87-95.

abstract: ABSTRACT German history during the 20th century was extremely complex—containing numerous events that can be labelled horrific and traumatic. The horrors and traumas of WWII forced Germans to actively address their country’s National Socialist pasts by taking responsibility for their roles, creating a national memory about the Nazi atrocities and implementing the reparations program, the Wiedergutmachungsabkommen, with the newly formed nation of Israel. The social theorist Theodor Adorno wrote in his 1959 essay “Was bedeutet: Aufarbeitung der Vergangenheit?” about three subtly nuanced terms: Aufarbeitung der Vergangenheit, Verarbeitung der Vergangenheit and Vergangensheitbewältigung, in which he addresses the various ways that Germany was dealing with traumatic events from this National Socialist past. Adorno specifically demanded a constant renegotiation of the past or Verarbeitung der Vergangenheit because it is the only way forward, through which people remember the horrors and atrocities of the past and work towards not allowing those events to occur again. This thesis applies the theoretical framework set forth by Adorno to explore efforts to engage the DDR and Stasi past after the Fall of the Wall and reunification. Specifically, it examines the concept of Verarbeitung der Vergangenheit and demonstrates how Thomas Brussig’s satirical novel Helden wie wir, and two documentary films Aus Liebe zum Volk and Das Wunder von Leipzig are examples of working upon this DDR and Stasi past. More specifically, the utilization of humor in the novel and the paralanguage modifications in the films provide insight to the feelings and emotions that individuals had about their pasts in the DDR. It is through this expression of emotion and feelings while writing and speaking about the past, which serves as the immediate moment when individuals actively working upon their pasts. / Dissertation/Thesis / Masters Thesis German 2016

I examine the relation between the action of producing a change (kinêsis) in something else and the action of exercising one’s nature or craft (energeia). I call for the distinction between kinêsis and energeia by arguing that in Metaphysics IX.1-5 change should be construed as a transformational change that is still characterized in accordance with the categories, whereas in Met. IX.6-9 the action of exercising of one’s nature or craft should be construed as the presence of a state or an action that exhibits one’s nature or craft, which is meant to be a way of characterizing that-which-is (to on) that goes beyond the categories. Instead of the conventional patient-centered account of change, I argue that Phys. III.3 and V.4 suggest a non-patient-centered account of change and that the agent’s acting-upon (poiêsis) should also be construed as a non-self-contained change, just as the patient’s being-acted-upon (pathêsis), and therefore cannot be conflated with exercising one’s nature or craft. I also point out that a genuine Aristotelian event cannot be composed of the agent’s acting-upon and the patient’s being-acted-upon. I argue that Phys. VII.3 suggests a two-way relation between the action of producing a change in something else and the action of exhibiting one’s own nature, based on which I outline a hylomorphic proposal that a genuine Aristotelian event is composed of the action of producing a change in something else as the material part of the event and the action of exhibiting one’s own nature as the formal part of the event. While the former provides the material necessitation force from the bottom up to the occurrence of the event, the latter provides the formal constraint force from the top down to the occurrence of the event. / text

Thesis (M.A.)--University of Wyoming, 2008. / Title from PDF title page (viewed on Nov. 18, 2009). Includes bibliographical references (p. 117-121).

Calcineurin (CaN) is a highly regulated Ser/Thr protein phosphatase that plays critical roles in learning and memory, cardiac development and function, and immune system activation. Alterations in CaN regulation contribute to multiple disease states such as Down syndrome, cardiac hypertrophy, Alzheimer’s disease, and autoimmune disease. In addition, CaN is the target of the immunosuppressant drugs FK506 and cyclosporin A. Despite its importance, CaN regulation is not well understood on a molecular level. Full CaN activation requires binding of calcium-loaded calmodulin (CaM), however little is known about how CaM binding releases CaN’s autoinhibitory domain from the active site. Previous work has demonstrated that the regulatory domain of CaN (RD) is disordered. The binding of CaM to CaN results in RD folding. Folding of the RD in turn causes the autoinhibitory domain (AID) located C-terminal to the RD to be ejected from CaN’s active site. This binding-induced disorder-to-order transition is responsible for the activation of CaN by CaM. In this work, we explore the nature of the disorder in the RD and its transition to an ordered state, demonstrating that the RD exists in a compact disordered state that undergoes further compaction upon CaM binding. We also demonstrate that a single CaM molecule is responsible for binding to and activating CaN. Finally, we determine that the CaM binding to CaN induces an amphipathic helix (the distal helix) C-terminal to the CaM binding region. The distal helix undergoes a hairpin-like chain reversal in order to interact with the surface of CaM, resulting in the removal of the AID from CaN’s active site. We employ site-directed mutagenesis, size-exclusion chromatography, protein crystallography, circular dichroism spectroscopy, fluorescence anisotropy and correlation spectroscopy, and phosphatase activity assays to investigate the ordering of CaN’s regulatory domain, the stoichiometry of CaN:CaM binding, and the impact of the distal helix on CaM activation of CaN.

This thesis focuses on state aid law as a specific part of EU competition law. State aid is therefore primarily set in the context of protection of competition in the EU internal market. Furthermore, the thesis provides an interpretation of Article 107, paragraph 1 of the Treaty on the Functioning of the European Union, which contains four attributes of state aid: state resources, favoring certain undertaking or the production of certain goods, distortion of competition and effect on trade between EU Member States. Analysis of the attribute "effect on trade between Member States" is made in a separate part of the work. In this section, the work seeks to explore how European Commission and the Court of Justice of the European Union approach and interpret this attribute. Attention is paid especially to decision-making activities of the European Commission in recent years. Decisions of the Commission, as a body authoritatively determining whether a measure constitutes state aid, as well as the compatibility of state aid with the internal market, could also indicate the direction in which the state aid law will develop in the future. The analysis of the Commission's decisions found that not even potentially affects trade between Member States a measure with purely local impact. Such measure will...