In the last year more and more measles cases have been reported in Rinkeby-Kista due to the fact that it is one of the few areas in Sweden with low vaccination coverage. As a consequence, political parties have proposed a vaccination requirement for preschool to protect vulnerable children who, for various medical reasons, can not vaccinate. This study illustrates how preschool leaders at independent and municipal preschools in the district of Rinkeby-Kista in Stockholm address the politicians’ bill on a possible vaccination requirement for preschool. Furthermore, the study illustrates how these preschool leaders handle the question of vaccination as an intercultural dilemma at preschool. The purpose is investigated using qualitative interviews where four preschool leaders are interviewed and the results are analyzed from an intercultural perspective. The result of the study shows that the preschool leaders would feel safe with some type of control of the children who are not vaccinated when they are part of a collective at preschool. But at the same time, there is a fear that it could lead to a categorization of children in society. The majority of preschool leaders did not consider it their task to handle the vaccination question at preschool and referred to BVC and current laws when different interests were posed against each other. It was only one preschool leader who participated in handling the vaccination question at preschool and was interested in intercultural meetings with the parents to conduct a dialogue together.