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Value-based decision making and alcohol use disorder / Wertbasierte Entscheidungsprozesse und AlkoholkonsumstörungenNebe, Stephan 15 March 2018 (has links) (PDF)
Alcohol use disorder (AUD) is a widespread mental disease denoted by chronic alcohol use despite significant negative consequences for a person’s life. It affected more than 14 million persons in Europe alone and accounted for more than 5% of deaths worldwide in 2011-2012. Understanding the psychological and neurobiological mechanisms driving the development and maintenance of pathological alcohol use is key to conceptualizing new programs for prevention and therapy of AUD. There has been a variety of etiological models trying to describe and relate these mechanisms. Lately, the view of AUD as a disorder of learning and decision making has received much support proposing dual systems to be at work in AUD – one system being deliberate, forward-planning, and goal-directed and the other one reflexive, automatic, and habitual. Both systems supposedly work in parallel in a framework of value-based decision making and their balance can be flexibly adjusted in healthy agents, while a progressive imbalance favoring habitual over goal-directed choice strategies is assumed in AUD. This imbalance has been theoretically associated to neural adaptations to chronic alcohol use in corticostriatal pathways involved in reward processing, especially in ventral striatum. However, these theoretical models are grounded strongly on animal research while empirical research in the human domain remains rather sparse and inconclusive. Furthermore, alterations in value-based decision-making processes and their neural implementation might not only result from prolonged alcohol misuse but may also represent premorbid interindividual differences posing a risk factor for the development of AUD.
Therefore, I here present three studies investigating the relation of alcohol use with the balance between goal-directed and habitual decision systems and with parameters modulating option valuation processes of these systems, namely delay, risk, and valence of option outcomes. To separate the investigation of these decision processes as predisposing risk for or consequence of alcohol use, two samples were examined: one sample of 201 eighteen-year-old men being neither abstinent from nor dependent on alcohol as well as one sample of 114 AUD patients in detoxification treatment and 98 control participants matched for age, sex, educational background, and smoking status. Both samples had a baseline assessment of several behavioral tasks, questionnaires, and neuropsychological testing and were followed-up over one year to examine drinking trajectories in the sample of young men and relapse in detoxified patients. The behavioral tasks included a sequential choice task using model-free and model-based reinforcement learning as operationalization of habitual and goal-directed decision making, respectively, during functional magnetic resonance imaging and four tasks probing participants’ delay discounting, probability discounting for gains and losses, and loss aversion.
Study 1 presents the cross-sectional analysis of the sequential choice task in relation to baseline drinking behavior of the young-adult sample. These analyses did not reveal an association between non-pathological alcohol use and habitual and goal-directed control on neither a behavioral nor neural level except for one exploratory finding of increased BOLD responses to model-free habitual learning signals in participants with earlier onset of drinking. Study 2 examined the same task in AUD patients compared to control participants showing no difference in behavioral control or neural correlates between those groups. However, prospectively relapsing AUD patients showed lower BOLD responses associated to model-based goal-directed control than abstaining patients and control participants. Additionally, the interaction of goal-directed control and positive expectancies of alcohol effects discriminated subsequently relapsing and abstaining patients revealing an increased risk of relapse for those patients who showed higher levels of goal-directed control and low alcohol expectancies or low levels of goal-directedness and high expectancies. Study 3 examined modulating features of goal-directed and habitual option valuation – delay, risk, and valence of options – in association to alcohol use in the young-adult sample and AUD status in the sample of patients and matched control participants on a cross-sectional as well as longitudinal level. This study revealed no relation of delay, risk, and loss aversion with current alcohol use and consumption one year later in the young men. In contrast, AUD patients showed systematically more impulsive choice behavior than control participants in all four tasks: a higher preference for immediate rewards, more risky choices when facing gains and less when facing losses, and lower loss aversion. Furthermore, a general tendency to overestimate the probability of uncertain losses could predict relapse risk over the following year in AUD patients.
Taken together, these results do not support the hypothesis that mechanisms of value-based decision making might be predisposing risk factors for alcohol consumption. The findings for patients already suffering from AUD are mixed: while choice biases regarding delays, risks, and valence of option outcomes seem to be altered systematically in AUD, there was no indication of an imbalance of habitual and goal-directed control. These findings challenge the assumption of a generalized outcome-unspecific shift of behavioral control from goal-directed to habitual strategies during the development of AUD and point towards several possible future avenues of research to modify or extend the theoretical model.
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Co-creating a sustainability strategy in a Product/Service-System value-based network of stakeholdersMateu, Adrià Garcia i, Li, Zhe, Tyson, Petronella January 2012 (has links)
This thesis project extends current research on how Product-Service/Systems (PSS) increase the competitiveness of what businesses provide to society. In particular, when the significant stakeholders who create value, structured as a network, are also involved in the co-development of the value proposition. Applying the Framework for Strategic Sustainable Development (FSSD), this study looks at how the early stages of a strategic planning process for sustainability could improve this co-development of PSS. The field research helped to understand the particularities of co-developing PSS and how the planning process could be adapted using the FSSD. As a result, theoretical dimensions, and general guidelines to put these into practice, are recommended in a model. The theoretical dimensions were field tested and refined. It was discovered that when creating the aspirational goals of the network, including other perspectives, in addition to companies and the customer’s, could expand the perception of value available to be provided. To do so is proposed a systematic understanding of the situation, and its socio-ecological context, where the activities of the value-based network of stakeholders are performed.
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Serving specialized patient segments in a diversified context : A knowledge perspective on the case of Karolinska University LaboratoryLöfgren, Anna, Danared, Filippa January 2017 (has links)
Fragmentation in healthcare has led to a desire to align and integrate care processes horizontally. The concept of value-based healthcare has been introduced, suggesting a maximized value creation to occur when optimal conditions are created for selected patient segments, integrating all activities that jointly determine the success in meeting a set of patient needs. While targeting specialized segments has been shown to be beneficial, theories of diversification suggests that an increased scope may be an even more efficient approach to improve performance. By sharing resources and capabilities across several specialized units, coordination and knowledge sharing of a hospital’s ancillary services becomes important. In this study, we examine how an ancillary service function, providing resources and capabilities that are shared across specialized units, can be organized to ensure contribution to the overarching goal of maximizing value for patients. This is done through a qualitative case study of the Karolinska University Laboratory – an ancillary service function of the Karolinska University Hospital. It is concluded that an ancillary service function can, in a diversified context, facilitate and support the value creation around medical conditions by developing a comprehensive structure for knowledge management and sharing, both externally towards medical conditions and internally within the ancillary service function. If structured properly, clear benefits, such as economies of scale, scope and knowledge spillovers, can be achieved by separating sharable resources from the patient flows.
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Mentorship narratives in a local congregation : a postfoundational practical theological studyVan der Westhuizen, Zander 07 April 2009 (has links)
In this study narratives of mentorship are listened to and described from the local context of the Dutch Reformed Church Lynnwood. These narratives originate from the mentorship programme in the youth ministry of the congregation. The research approach in this study flows from an epistemology based on narrative theory, social constructionism and a postfoundational approach. It is a practical theological study that aims to come to a greater understanding of these narratives. Based on the epistemology discussed here, I position myself within the framework of a postfoundational practical theology. Within this framework the praxis is the starting point of this research. This is local knowledge, interpreted and described by a community of co-researchers as informed by traditions of interpretation. The in-context experiences are interpreted and thickened through interdisciplinary investigation. This is done through a study of relevant literature as well as interdisciplinary discussion based on the theory of transversal rationality. At the end of this research process, alternative interpretations and suggestions are made that point beyond this local context and contribute to the larger field of mentorship. The research process in this study is developed from the postfoundational practical theological positioning. Seven movements are used to listen to the narratives of the eight co-researchers participating in this study. The narratives of the co-researchers lead to the identification of certain themes from their experiences that resonate with themes available to us in literature. The same themes also emerge from the interdisciplinary conversation in this study. These themes are critically discussed and certain questions are raised with regards to mentorship and the way mentorship is understood in different contexts. The issue of language and how the various fields concerned with mentorship use language is discussed. It is clear from this study that the local context of mentorship in this study differs in certain aspects from other contexts where mentorship is practiced. The difference between coaching and mentorship is investigated and reflected upon. I argue in the concluding chapter that from this context three basic foundation blocks for mentorship emerge. Firstly, the relationship forms the first basic building block of mentorship. Secondly, growth is the second basic building block and also the aim of mentorship. Although the way growth is understood may vary from context to context, it still forms one of the basic building blocks of mentoring relationships. The third basic building block is the fact that the mentorship relationship is reciprocal. I suggest an approach to mentorship that emerged from the narratives of the local praxis studied. This approach is based on values. The following values are suggested as necessary in a meaningful mentorship programme or relationship: clarity, context, the ordinary, relationship, listening, adding value, reflection and ethics. I conclude that mentorship is a landscape with many voices. The values suggested in this study can be used to construct the understanding of mentorship in a specific, local context. This is done with the aim to facilitate a meaningful mentorship programme or relationship. / Thesis (PhD)--University of Pretoria, 2009. / Practical Theology / unrestricted
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Management znalostí / Knowledge managementJarošová, Milena January 2008 (has links)
Theoretical part: Basic terms of knowledge management, knowledge worker, knowledge creation and conversion process, prerequisites and benefits of knowledge management. Knowledge management and it's connection to organizational culture and structure, result measurements of knowledge management, learning organization and it's connection to knowledge management. Tacit knowledge management tools -- stories -- types, how to create, practical use, communities, coaching. Value Based Organization. Practical part: Characteristics of organization, value based organization in reality, classification of stories from organization, organizational values, stories in detail, stories in customer care, stories in back line departments. Propsal on improvement of tacit knowledge management in organization -- employee training, mutual inspiration, front line department visits, modifications of organizational values.
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Hodnocení výkonnosti ve firmě / The Evaluation of the Efficiency in the FirmTydlačková, Pavlína January 2010 (has links)
This master`s thesis is focused on the evaluation of the efficiency in the firm of Josef Filák in the years 2006-2008 by using selected methods of financial analysis and Economic Value Added. Based on results from analysis are created suggestions for an improvement present situation in the firm for several following years.
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Wertstromdesign als Instrument der wertorientierten UnternehmensführungLee, Yong 11 June 2014 (has links)
Wertorientierte Unternehmensführung, Wertstromdesign als zentrale Methode des Lean Managements und die Flexibilität von Produktionssystemen haben sich als Managementansätze in der Vergangenheit bewährt.
Die Koexistenz dieser Ansätze stellt Führungskräfte vor die tägliche Herausforderung, ihren jeweiligen Beitrag zur wertorientierten Unternehmensführung zu erkennen, operative Entscheidungen zu treffen und auf diese Weise die Wettbewerbsfähigkeit des Unternehmens im Spannungsfeld der Interessen der Anspruchsgruppen sicherzustellen.
Unter der leitenden Forschungsfrage, welchen Beitrag das Wertstromdesign als Instrument der wertorientierten Unternehmensführung zum Unternehmenswert unter Beachtung der Flexibilität des Produktionssystems leistet, werden die Einzelkonzepte detailliert betrachtet, wesentliche Einflussgrößen sowie deren durch Reduktion von Komplexität entstehende Wechselwirkungen identifiziert und zur Handlungsorientierung methodisch gestützte Gestaltungsempfehlungen formuliert.:1 Einleitung … 1
1.1 Behandlung des Themas in der Literatur … 4
1.1.1 Wertstromdesign … 4
1.1.2 Flexibilität des Produktionssystems … 6
1.1.3 Wertorientierte Unternehmensführung … 8
1.2 Problemstellung und Zielsetzung … 11
1.3 Struktur der Arbeit und Vorgehensweise … 12
2 Theoretischer Bezugsrahmen … 15
2.1 Systemtheoretischer Ansatz zur Reduktion der Komplexität … 15
2.1.1 Begriffliche Abgrenzung und Arbeitsdefinition … 16
2.1.2 Ansatz der allgemeinen Systemtheorie … 17
2.1.2.1 Das Produktionssystem als Erfahrungsobjekt … 18
2.1.2.2 Der Wertstrom als Erkenntnisobjekt … 19
2.2 Wertstromdesign als Gestaltungsmethode … 20
2.2.1 Definition und Abgrenzung zu anderen Methoden … 20
2.2.1.1 Definition … 21
2.2.1.2 Abgrenzung zu anderen Lean-Methoden … 22
2.2.1.3 Abgrenzung zu anderen Prozessoptimierungsmethoden … 23
2.2.2 Vorgehensweise … 24
2.2.2.1 Festlegung der Produktfamilie … 24
2.2.2.2 Wertstromanalyse … 27
2.2.2.3 Wertstromdesign … 30
2.2.3 Zusammenfassung … 33
2.3 Flexibilität von Produktionssystemen … 34
2.3.1 Definition und begriffliche Abgrenzung … 34
2.3.1.1 Allgemeine Definitionen … 35
2.3.1.2 Abgrenzung von Agilität und Wandlungsfähigkeit … 37
2.3.2 Klassifizierung der Flexibilitätstypen … 39
2.3.2.1 Horizontale Klassifizierung … 39
2.3.2.2 Vertikale Klassifizierung … 41
2.3.2.3 Sonstige Klassifizierungen … 42
2.3.3 Messung der Flexibilität … 44
2.3.3.1 Zeit als Maß für die Flexibilität … 44
2.3.3.2 Kosten als Maß für die Flexibilität … 45
2.3.3.3 Wahrscheinlichkeit als Maß für die Flexibilität … 47
2.3.4 Zusammenfassung … 47
2.4 Wertorientierte Unternehmensführung … 48
2.4.1 Begriffliche Abgrenzung und Definition … 49
2.4.1.1 Shareholder-Value-Ansatz … 49
2.4.1.2 Stakeholder-Ansatz … 50
2.4.1.3 Arbeitsdefinition … 51
2.4.2 Wertorientierte Kennzahlenkonzepte … 52
2.4.2.1 Definition und Verwendung des Cashflows … 53
2.4.2.2 Discounted Cash-Flow (DCF) … 55
2.4.2.3 Shareholder Value Added (SVA) … 58
2.4.2.4 Cash Flow Return on Investment (CFROI) und Cash Value Added (CVA) … 59
2.4.2.5 Economic Value Added (EVA) … 61
2.4.3 Operationalisierung der wertorientierten Kennzahlenkonzepte … 63
2.4.3.1 Kennzahlensystem … 64
2.4.3.2 Werttreiberhierarchie … 64
2.5 Zusammenfassung … 65
3 Empirische Bestimmung von Wertstromtypen … 68
3.1 Modell zur Schätzung des Wertbeitrags durch das Wertstromdesign … 68
3.1.1 Bestimmung der Einflussgrößen … 69
3.1.1.1 Bestimmung der Erfolgsfaktoren und Kennzahlen … 69
3.1.1.2 Bestimmung der relevanten Flexibilitätstypen … 75
3.1.2 Konzeption des Modells zur Schätzung des Wertbeitrags … 76
3.1.2.1 Aufbau des Modells … 76
3.1.2.2 Ansatz zur Schätzung des Wertbeitrags … 78
3.2 Empirische Analyse zur Bestimmung von Wertstromtypen … 81
3.2.1 Datenbasis und Erhebungsmethodik … 81
3.2.1.1 Inhalt der Unternehmensbefragung … 82
3.2.1.2 Struktur der Grundgesamtheit … 82
3.2.2 Analyse der empirischen Datenbasis … 84
3.2.2.1 Gewichtung und Einfluss der Kennzahlen … 84
3.2.2.2 Faktorenanalyse … 90
3.2.2.3 Clusteranalyse … 94
3.3 Charakterisierung der Wertstromtypen … 97
3.3.1 Klassifizierungsmerkmale von Wertstromtypen … 98
3.3.2 Ableitung der idealisierten Wertstromtypen … 102
3.3.2.1 Cluster 1: Wertstromtyp „Balanced“ … 102
3.3.2.2 Cluster 2: Wertstromtyp „Pending“ … 03
3.3.2.3 Cluster 3: Wertstromtyp „Project“ … 104
3.3.2.4 Cluster 4: Wertstromtyp „Service“ … 105
3.3.3 .bersicht: Wertstromtypen … 106
3.4 Zusammenfassung … 10
4 Gestaltungsfelder des wertorientierten Wertstromdesigns unter
Berücksichtigung der Flexibilität des Produktionssystems … 113
4.1 Ableitung der Gestaltungsfelder … 113
4.1.1 Gestaltungsansätze für die Haupteinflussgrößen … 113
4.1.1.1 Ansätze des Qualitätsmanagements … 113
4.1.1.2 Ansätze des Zeitmanagements … 16
4.1.2 Definition der Gestaltungsfelder … 117
4.1.2.1 Vier Gestaltungsfelder des wertorientierten Wertstromdesigns … 118
4.1.2.2 Einfluss der Gestaltungsmethoden auf die Flexibilitätsarten … 120
4.2 Gestaltungsfelder des wertorientierten Wertstromdesigns … 122
4.2.1 Fehlervermeidung … 122
4.2.1.1 Analyse der Fehlerrisiken im Ist-Wertstrom … 122
4.2.1.2 Reduzierung der Risiken im Soll-Wertstrom … 125
4.2.2 Fehlerabsicherung … 127
4.2.2.1 Fehleranalyse im Ist-Wertstrom … 127
4.2.2.2 Statistische Prozesskontrolle im Soll-Wertstrom … 130
4.2.3 Reduzierung der Komplexität … 134
4.2.3.1 Analyse der Produktkomplexität im Wertstrom … 135
4.2.3.2 Gestaltung eines wertstromgerechten Produktdesigns … 137
4.2.3.3 Analyse der Fertigungsorganisation … 139
4.2.3.4 Gestaltung wandlungsfähiger Fertigungssegmente …142
4.2.4 Stabilisierung und Optimierung des Prozesses … 144
4.2.4.1 Analyse des Informationsflusses … 144
4.2.4.2 Leitlinien zur Gestaltung des Material- und Informationsflusses … 146
4.2.4.3 Analyse der personalkritischen Engpässe … 148
4.2.4.4 Ma.nahmen zum Kapazitätsausgleich … 151
4.3 Zusammenfassung … 153
5 Fallstudien und Gestaltungsempfehlungen für das wertorientierte
Wertstromdesign … 156
5.1 Auswahl der Fallstudien … 156
5.2 Ausgangssituation … 157
5.2.1 Fallstudie 1: Wertstromtyp „Balanced“ … 157
5.2.2 Fallstudie 2: Wertstromtyp „Pending“ … 62
5.2.3 Fallstudie 3: Wertstromtyp „Project“ … 65
5.2.4 Fallstudie 4: Wertstromtyp „Service“ … 168
5.3 Gestaltungsempfehlungen … 172
5.3.1 Wertstromtyp „Balanced“ … 172
5.3.2 Wertstromtyp „Pending“ … 174
5.3.3 Wertstromtyp „Project“ … 176
5.3.4 Wertstromtyp „Service“ … 177
5.4 Zusammenfassung … 180
6 Zusammenfassung und Ausblick … 183
7 Literaturverzeichnis … 187
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Value-based decision making and alcohol use disorderNebe, Stephan 17 January 2018 (has links)
Alcohol use disorder (AUD) is a widespread mental disease denoted by chronic alcohol use despite significant negative consequences for a person’s life. It affected more than 14 million persons in Europe alone and accounted for more than 5% of deaths worldwide in 2011-2012. Understanding the psychological and neurobiological mechanisms driving the development and maintenance of pathological alcohol use is key to conceptualizing new programs for prevention and therapy of AUD. There has been a variety of etiological models trying to describe and relate these mechanisms. Lately, the view of AUD as a disorder of learning and decision making has received much support proposing dual systems to be at work in AUD – one system being deliberate, forward-planning, and goal-directed and the other one reflexive, automatic, and habitual. Both systems supposedly work in parallel in a framework of value-based decision making and their balance can be flexibly adjusted in healthy agents, while a progressive imbalance favoring habitual over goal-directed choice strategies is assumed in AUD. This imbalance has been theoretically associated to neural adaptations to chronic alcohol use in corticostriatal pathways involved in reward processing, especially in ventral striatum. However, these theoretical models are grounded strongly on animal research while empirical research in the human domain remains rather sparse and inconclusive. Furthermore, alterations in value-based decision-making processes and their neural implementation might not only result from prolonged alcohol misuse but may also represent premorbid interindividual differences posing a risk factor for the development of AUD.
Therefore, I here present three studies investigating the relation of alcohol use with the balance between goal-directed and habitual decision systems and with parameters modulating option valuation processes of these systems, namely delay, risk, and valence of option outcomes. To separate the investigation of these decision processes as predisposing risk for or consequence of alcohol use, two samples were examined: one sample of 201 eighteen-year-old men being neither abstinent from nor dependent on alcohol as well as one sample of 114 AUD patients in detoxification treatment and 98 control participants matched for age, sex, educational background, and smoking status. Both samples had a baseline assessment of several behavioral tasks, questionnaires, and neuropsychological testing and were followed-up over one year to examine drinking trajectories in the sample of young men and relapse in detoxified patients. The behavioral tasks included a sequential choice task using model-free and model-based reinforcement learning as operationalization of habitual and goal-directed decision making, respectively, during functional magnetic resonance imaging and four tasks probing participants’ delay discounting, probability discounting for gains and losses, and loss aversion.
Study 1 presents the cross-sectional analysis of the sequential choice task in relation to baseline drinking behavior of the young-adult sample. These analyses did not reveal an association between non-pathological alcohol use and habitual and goal-directed control on neither a behavioral nor neural level except for one exploratory finding of increased BOLD responses to model-free habitual learning signals in participants with earlier onset of drinking. Study 2 examined the same task in AUD patients compared to control participants showing no difference in behavioral control or neural correlates between those groups. However, prospectively relapsing AUD patients showed lower BOLD responses associated to model-based goal-directed control than abstaining patients and control participants. Additionally, the interaction of goal-directed control and positive expectancies of alcohol effects discriminated subsequently relapsing and abstaining patients revealing an increased risk of relapse for those patients who showed higher levels of goal-directed control and low alcohol expectancies or low levels of goal-directedness and high expectancies. Study 3 examined modulating features of goal-directed and habitual option valuation – delay, risk, and valence of options – in association to alcohol use in the young-adult sample and AUD status in the sample of patients and matched control participants on a cross-sectional as well as longitudinal level. This study revealed no relation of delay, risk, and loss aversion with current alcohol use and consumption one year later in the young men. In contrast, AUD patients showed systematically more impulsive choice behavior than control participants in all four tasks: a higher preference for immediate rewards, more risky choices when facing gains and less when facing losses, and lower loss aversion. Furthermore, a general tendency to overestimate the probability of uncertain losses could predict relapse risk over the following year in AUD patients.
Taken together, these results do not support the hypothesis that mechanisms of value-based decision making might be predisposing risk factors for alcohol consumption. The findings for patients already suffering from AUD are mixed: while choice biases regarding delays, risks, and valence of option outcomes seem to be altered systematically in AUD, there was no indication of an imbalance of habitual and goal-directed control. These findings challenge the assumption of a generalized outcome-unspecific shift of behavioral control from goal-directed to habitual strategies during the development of AUD and point towards several possible future avenues of research to modify or extend the theoretical model.:Table of Contents
List of Figures
List of Tables
List of Abbreviations
Abstract
Chapter 1. Perspectives on alcohol use disorder
1.1 The size of alcohol use disorder
1.1.1 Terminology of alcohol-use related disorders
1.1.2 Size and burden of alcohol consumption and alcohol use disorders
1.2 Cognitive psychological perspectives on alcohol use disorder
1.2.1 A unified framework for addiction
1.2.2 Value-based decision making
1.2.3 Goal-directed and habitual systems
1.3 Neurobiological perspectives on alcohol use disorders
1.3.1 Neural underpinnings of the reward circuit
1.3.2 Neural underpinning of goal-directed and habitual decision making
1.3.3 Striatal adaptations associated with chronic alcohol consumption
1.4 Synopsis and research questions
Chapter 2. Study 1
2.1 Abstract
2.2 Introduction
2.3 Material and methods
2.3.1 Participants and procedure
2.3.2 Measures of goal-directed and habitual behavioral control
2.3.3 Measure of alcohol consumption
2.3.4 Behavioral statistical analyses
2.3.5 Functional magnetic resonance imaging data acquisition and analysis
2.4 Results
2.4.1 Sample characteristics
2.4.2 Behavioral results
2.4.3 Functional magnetic resonance imaging results
2.5 Discussion
Chapter 3. Study 2
3.1 Abstract
3.2 Introduction
3.3 Methods and materials
3.3.1 Participants
3.3.2 Procedure
3.3.3 Alcohol Expectancy Questionnaire
3.3.4 Task
3.3.5 Magnetic Resonance Imaging
3.3.6 Follow-up procedure
3.3.7 Data analysis
3.3.8 fMRI analysis
3.4 Results
3.4.1 Sample characteristics
3.4.2 Task-related group differences
3.4.3 Interaction between alcohol expectancies and model-based control
3.4.4 fMRI results
3.5 Discussion
Chapter 4. Study 3
4.1 Abstract
4.2 Introduction
4.3 Study 3.1
4.3.1 Material and methods
4.3.2 Results
4.4 Study 3.2
4.4.1 Material and methods
4.4.2 Results
4.5 Discussion
Chapter 5. General discussion
5.1 Summary of findings and discussion
5.1.1 Goal-directed and habitual decision making and alcohol use (disorder)
5.1.2 Neuroimaging correlates of goal-directed and habitual control
5.1.3 Modulators of the valuation systems and alcohol use (disorders)
5.1.4 Integration of findings
5.2 Limitations
5.2.1 Methodological critique of the Two-Step task
5.3 Outlook for future studies
5.3.1 Tentative framework for future studies
5.4 Conclusions
References
Appendix
A Supplementary Information of Study 1
A.1 Supplementary Methods 1 - behavioral
A.2 Supplementary Methods 2 - fMRI
A.3 Supplementary Results - behavioral
A.4 Supplementary results - fMRI
B Supplementary Information of Study 2
B.1 Computational fits
B.2 Preprocessing of the functional imaging data
B.3 Exclusion criteria for different analyses
B.4 First level analysis of the functional imaging analysis
B.5 Voxel-based morphometry
B.6 Drinking Motives Questionnaire
B.7 Model-free comparisons
B.8 Association with time to relapse
B.9 Number of detoxifications and model-based control: behavioral and neuroimaging analyses
C Supplementary Information of Study 3
C.1 Differences between VBDM version used in this study compared to the VBDM version reported in Pooseh et al. (under review)
C.2 Additional correlational analyses
D Supplementary Information for additional analyses
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Relationship Between Hospital Size, Staff Communication, Physician Communication, and Patient Experience ScoresLayton, Cheryl Marie 01 January 2019 (has links)
Healthcare leaders who struggle to understand the importance of interactions between patients, staff, and physicians can result in poor patient experience. Healthcare care leaders who understand the importance of patient experience can develop customer service training modules and tutorials to improve organizational outcomes. The purpose of this correlational study was to examine the relationship between staff communication, physician communication, size of the hospital, and patient experience. House's path-goal theory was used to frame the study. Secondary data were collected from hospitals in Northeastern Ohio, that reported patient experience scores through the Centers for Medicare and Medicaid's Hospital Consumer Assessment of Healthcare Providers and Systems survey database for the years 2016 and 2017. The results of the multiple linear regression indicated the results were significant, F(5, 144) = 56.822, p <.001, R2 = .652. The findings may provide health care leaders with tools to communicate with staff on how to improve patient experience through improving employee and patient engagement, thereby improving patient experience scores.
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Výchova k hodnotám prostřednictvím metody Persona Dolls / Value - based education using Method Persona DollsLišková, Kateřina January 2019 (has links)
This thesis deals with Method Persona Dolls, which evolves children's approach and values, it is pre-eminently focused on empathy development, creativity, self-confidence, positive evaluation of others and forms of pro-social behaviour. The theoretical part is focused on the description of curriculum reforms and characteristic of curriculum documents in general, particularly on Framework Educational Programme for Basic Education. The theoretical part further deals with this method from the point of view of theoretical principles, methods of its use and contribution, but from the point of drawback as well, which can occur when using this method. The method is also analysed from the point of view of curriculum documents as a possible tool for key competencies development. In addition, it is concerned about emotional intelligence and grade-schoolers emotional development, values and emotion description. Furthermore, the concept of value-based education of Cyril Mooney will be concerned as next item. Both methods are compared and I search for possible linkage between Method Persona Dolls and strategies used in value education. The action research will form the research part of the thesis, in which the empathy development and communicative competence of pupils using the Persona Dolls Method is...
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