The ancient glass collection of the National Museum has more than 200 completely intact and so far - beside few exceptions - unpublished vessels which encompass a wide chronological framework from the 5th century BC until the end of antiquity. The core of the collection is composed of mold-blown and free-blown glass. The analysis of the collection offers a view into the history of the ancient glass production; examples of all kinds of production methods can be found in it - from a corn-formed glass, through a glass made by sagging into a form, and up to a mold-blown and free-blown glass. A great number of various decoration techniques and styles used in antiquity are represented in the collection; also, it contains vessels from various places within the Roman Empire, as well as outside of it. The major part of the work comprises blown glass from the Roman imperial period (chapter four), both free-blown and mold-blown, and from this virtually half are unguentaria of various types. Almost all types of vessel produced in this period are found in this chapter. The vessels were ordered according to types - e.g. open shapes, closed shapes and in the framework of these types they are arranged further - according to other criteria which create other sub-groups - as for example forms without a foot or on a...

Title: Acipimox during Short-Term Exercise Exerts A Negative Feedback of Growth Hormone on Ghrelin Secretion in Patients with Bulimia Nervosa and in Healthy Women: The Role of Lipolysis Objective: Eating disorders, such as bulimia nervosa (BN) and anorexia nervosa (AN), are characterized by abnormal eating behavior. The main features of BN are binge-eating and inappropriate compensatory methods to prevent weight gain. The appetite-modulating peptide ghrelin is secreted by the stomach and shows a strong release of growth hormone (GH). A potential GH-ghrelin feedback loop between stomach and the pituitary has been recently reported. Acipimox (Aci), an analogue of nicotinic acid, inhibits lipolysis in adipose tissue (AT) and reduces plasma glycerol and free fatty acids (FFA) levels. Exercise and Aci are stimulators of GH secretion. We suppose that a negative feedback from increased GH levels during exercise may play a role in reducing plasma ghrelin levels. We surmised that altered baseline activity and exercise-induced activation of the sympathetic nervous system (SNS) results in excessive stimulation of lipolysis associated with negative energy balance and may lead to abnormal AT metabolism in patients with BN. Disruption of the gut-brain-AT axis might be involved in the pathogenesis of BN. The...

Diploma thesis deals with the relations between the contemporary free and applied art. It explores the possibilities of bidirectional permeation and trapping of these areas. In this thesis I´m trying to touch the border points between sculpture, painting, drawing and design Diploma work deals with the theme of the wall relief. I´m using conceptual principles and these principles are often unclear on the outside. by using the conceptual keys and contexts i´m trying to create the aesthetic quality of the artwork. In a practical thesisis i´m working with wall sculptures and folding picture. Art can often change their nature and their perceptions using a different composition, adjustment, or context with the surroundings. I´m working with possibilities of understanding to every single artistic element as part of a wider whole. This thesis consists of a wall relief sculptures. The composition components are all facing the wall, eventually. column. In this thesis combines the individual relief under a particular key.

This diploma thesis in its theoretical and practical parts focuses on free play of children in pre-school facilities. Kindergarten is the place of early secondary socialization of the child and that's why one part of the diploma thesis is centred on this theme. The theoretical part helps for a deeper understanding of play, especially with 2-4 year old children and builds a foundation for the research. The practical part, based on one year's observation, monitors development of free play of a homogeneous group of children and finds how the quality of play changes with individuals as well as the group. Another focus lies on comparing two separate groups of children in their free play - one group having long term experience with free play and one without such regular experience. The main method of the research is observation. The results of the research points to the importance of free play for a pre-school age child and confirms the influence of free play in the process of early secondary socialization.

This Diploma Thesis with a title "Future parents' way to foster care with a focus on adoption" has got two main parts. The theoretical part presents a basic approach on the issue of substitute care - family one as well as institutional one. It emphasizes its risks and also its advantages. One of the chapters describes the complete process of adoption, all steps, which applicants must get through and it emphasizes pitfalls of each step. The practical part is based on the theoretical part and it is in a form of an experimental probe. In the practical part there are presented the results of data analysis, which goes from semi-structured interviews with adoption applicants. The Thesis presents a complete overview of the issue of adoption and it also introduces not much discussed topic of direct adoption in the Czech Republic. Key words: Substitute Care, Foster Care, Forms of Foster Care, Institutional Care, Adoption, Direct Adoption, Parents' Approval to Adoption, "Legally Free" Child, Adoption Applicant

The thesis deals with the problem of large-capacity manipulation of large forgings with forging manipulator. It describes current techniques, their characteristics, advantages and disadvantages. Based on the analysis of these techniques, the thesis introduces design of the connection of the hydraulic circuit for the drive of the traveling traction wheels of the forging manipulator QKK 100 by ŽĎAS a.s. focusing on simplicity, trouble-free operation, efficiency, economy, change of speed and torque, and possibility of modification according to the current load.

This thesis deals with the total antioxidant activity (TAA) evaluation of various sorts of tea (green, black, half-fermented, white, mate, rooibos and herbal) depending on the process and time of their treatment. The main emphasis is put on testing a new method of measuring the total antioxidant activity by flow coulometry. The results acquired by this method are compared to the results of the chemiluminescent Trolox equivalent antioxidant capacity (TEAC) method which is a standard for measuring the total antioxidant capacity in various materials and raw materials. The work discusses the reasons for the differences in the values found by both methods.

Práce komplexně popisuje vodní a vodovzdušné chlazení pomocí metod CFD (Computational Fluid Dynamics) konkrétně s využitím software ANSYS FLUENT. Skládá se ze dvou hlavních částí, z nichž první se zabývá numerickým popisem jediné vodní kapky a druhá popisem směsí kapek představující paprsek válcové a ploché trysky. Je založena převážně na vícefázových modelech proudění a vlastních uživatelsky definovaných funkcí (User Defined Functions, UDF) představujících stěžejní část práce. Uvedené výpočtové modely jsou ve většině případů verifikovány pomocí experimentálních dat nebo jiných numerických modelů. V první části práce jsou teoreticky postupně rozebrány všechny tři použité vícefázové modely proudění. První z nich, Volume Of Fluid model (VOF), byl použit pro modelování jediné kapky (mikromodel). Zatímco zbývající dva, Euler-Euler model a Euler-Lagrange model, byly aplikovány v modelu celého paprsku trysky (makromodel). Mikromodel popisuje dynamiku volného pádu vodní kapky. Pro malé průměry kapek (~100µm) standardní model povrchového napětí (Continuum Surface Force, CSF) způsoboval tzv. parazitní proudy. Z toho důvodu je v práci rozebrána problematika výpočtu normál, křivostí volných povrchů a povrchového napětí jako zdroje objemových sil v pohybových rovnicích. Makromodel se zabývá studiem dynamiky celého paprsku tj. oblastí od ústí trysky po dopad na horký povrch, bere v úvahu kompletní geometrii, tzn. např. podpůrné válečky, bramu, spodní část krystalizátoru apod. V práci je rozebrána 2D simulace dopadu paprsku válcové trysky pomocí VOF modelu Euler-Lagrange modelu na horký povrch. Pro případ s VOF modelem byl navržen model blánového varu. Euler-Euler model a Euler-Lagrange model byly využity pro simulaci paprsku ploché trysky horizontálně ostřikující horkou bramu přímo pod krystalizátorem nad první řadou válečků. Pro Euler-Euler model byl navržen model sekundárního rozpadu paprsku založený na teorii nejstabilnější vlnové délky (Blob jet model). Jelikož diskrétní Lagrangeovy částice tvořily v určitých místech spíše kontinuální fázi, byl navržen a otestován model pro konverzi těchto částic do VOF.

This work presents the results ofour research of cell-free nucleic acids (cfNA). The first part shows changes in methylation patterns of immune response genes promoters that are detectable in plasma during the hemodialysis sessions and also differences in methylation between patients and healthy subjects. Alterations include genes that play their role in the regulation of hematopoiesis and these changes are in close relation with the need of anemia therapy. In the other plasma cfNA study we detected miRNA signatures in patients with acute myeloid leukemia at diagnosis (6 highly abundant miRNAs found) and in remission achieved after standard chemotherapy (trend to n01malization, lower levels ofthese miRNAs). Another part of work presents data from the study of potential non-invasive biomarker of bladder cancer. The amounts of cfDNA in urine are higher in patients than in healthy subjects and there were found 5 down-regulated miRNAs. Simultaneously it was established set of 30 miRNAs that are constantly present in urine supematants independently on sex, age and healthy status of subjects. The last part presents analysis ofcell-free fetal DNA. We analyzed differences between a new quantification method - droplet digital PCR and real-time PCR which is used routinely nowadays. Slightly more precise was...

This master’s thesis describes various principles of measurement of electromagnetic waves in a free space and on a line. Used sensors and their real parameters are given for every method. The analysis of protections of high-frequency inputs of measuring instruments is done here and the most suitable method and protections of input for realization are chosen. The analysis of design of secondary protection of high-frequency input is done in this project. The protection of input is realized and measured. The suitable method of measurement is chosen as well as the sensor for measurement of power. The block diagram and circuit diagram of the meter of power are designed. According to designed conception the measuring instrument for measurement of power is realized and its single qualities are measured during the realization. In the final part its precision is measured and the evaluation of results is done.