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本文係針對臺灣50指數期貨與基金於2003年6月30日上市之後，臺灣期貨及現貨市場報酬率間領先落後關係與波動性的變化來進行探討。研究分為兩部份，第一部份是觀察臺灣50指數期貨與現貨之間的關聯性，並探討臺灣加權股價指數、金融保險類股股價指數及電子類股股價指數期貨與現貨市場間的變化；第二部份是採用可模擬現貨走勢的臺灣50指數基金、國泰金及臺積電的股價來做為現貨的替代變數，觀察其與期貨之間的關連性是否與第一部份的結果類似，若是實證結果極為相同，則相關機構與一般投資人將可運用各期貨與其標的指數中市值最大的股票來進行套利操作。此外，本文在進行模型估計時，首度採用一階段估計法，來聯合估計雙變量GARCH模型中的條件平均數方程式與條件變異數方程式，以避免過去相關文獻將兩條方程式個別估計時所造成的估計誤差。 實證結果所獲得的重要結論如下：首先，臺灣期貨市場的發展仍未趨成熟，並不具有價格發現的功能，在考慮風險溢酬方面，僅有臺灣50指數期貨與現貨的投資人會在報酬率之外，額外要求用以補償的風險溢酬，再者，臺灣50指數期貨與基金的上市，並沒有對臺灣現有的期貨與現貨市場造成顯著的影響，然而，替代變數並不能完全取代現貨指數，但相較之下，國泰金在臺灣50指數期貨與基金上市之後的那段期間模擬成效最好。 / This paper investigates the change of lead-lag relationship in returns and volatilities in Taiwan futures and spot markets after the introduction of Taiwan 50 Futures and Taiwan Top50 Tracker Fund (TTT) on June 30, 2003. The study divides into two parts. The first part examines the relationship between Taiwan 50 Futures and spot markets, and also discusses the change of Taiwan Stock Exchange Capitalization Weighted Stock Index, Taiwan Stock Exchange Banking and Insurance Sector Index, and Taiwan Stock Exchange Electronic Sector Index in futures and spot markets. Another part uses the stock price of TTT, Cathay Financial Holding Company and Taiwan Semiconductor Manufacturing Company as the substitutive variables of spot index and goes a step further to examine the relationships between them and futures individually. Additionally, this research used One-Pass Method for first time to estimate jointly the conditional mean equation and conditional variance equation of Bivariate GARCH Model to avoid estimating error in previous relative studies with Two-Pass Method. The major empirical results are as follows: first, the development of Taiwan futures market is incomplete. The futures market does not play the price discovery role to the spot market. Second, under the consideration of risk premium, only investors in Taiwan 50 Futures and spot markets would ask for compensated risk premium excepting returns. Third, the opening of Taiwan 50 Futures and TTT does not influence significantly Taiwan futures and spot markets. Last but not least, these substitutive variables can not replace spot index perfectly. However, comparing with others, the stock price of Cathay Financial Holding Company is the very model of Taiwan Stock Exchange Banking and Insurance Sector Index after the introduction of Taiwan 50 Futures and TTT.

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Une étape clé dans la maturation des pré-ARNms est le clivage et la polyadénylation que ceux-ci subissent sur leur extrémité 3’. Chez les métazoaires, le complexe CstF (Cleavage stimulation Factor) reconnaît une région de l’ARNm riche en U et U/G et stabilise le complexe CPSF (Cleavage Polyadenylation Stimulating Factor) sur le site de polyadénylation. Nous avons déterminé la structure cristallographique du domaine N-terminal d’une des trois sous-unités de CstF, CstF-50. Ce domaine forme un homodimère compact et présente deux surfaces identiques conservées dérivées de la formation du dimère. La structure dimérique de CstF-50 est en accord avec le modèle hexamèrique du complexe. L’homologue de CstF chez la levure, CF IA (Cleavage/polyadenylation Factor IA), est impliqué dans les réactions de clivage et polyadénylation de la maturation 3’. Nous avons reconstitué le complexe entier ‘in vitro’ et résolu la structure en solution par RMN des régions minimales impliquées dans l’interaction des sous-unités Rna14p et Rna15p. Pour la formation de l’hétérodimère, la région C-terminale de Rna14p, que nous avons appelé domaine « monkeytail », s’entrelace intimement avec la région « hinge » de Rna15p. La présence de ces deux domaines chez leurs homologues de mammifères, CstF-77 et CstF-64, suggère la conservation de ce type d’organisation entre ces deux sous-unités à travers les espèces. / The removal of the 3’ region of pre-mRNA followed by polyadenylation is a key step in mRNA maturation. In metazoa, Cleavage stimulation Factor (CstF) recognizes U and G/U rich cis-acting RNA sequence elements through its 64kDa subunit and helps stabilize the Cleavage Polyadenylation Stimulating Factor (CPSF) complex at the polyadenylation site. We describe the crystal structure of the N-terminal domain of the CstF-50 subunit. Through highly conserved residues, CstF-50 forms a compact homodimer that exposes two geometrically opposite and identical conserved surfaces. Together with prior data, the structure of the CstF-50 homodimerization domain supports a hexameric model of CstF. The yeast homologue of CstF is the Cleavage/polyadenylation Factor IA (CF IA) complex and is involved in both the cleavage and polyadenylation of pre-mRNA. We have reconstituted ‘in vitro’ the overall complex and also solved the solution structure of one of the inter-subunit regions, specifically the heterodimer involving peptides from Rna14p and Rna15p. Upon binding, a short C-terminal region from Rna14p wraps intimately within the central hinge domain from Rna15p. Conservation of residues reveals that the structural tethering is preserved in the homologous mammalian proteins. / La maduración 3’ del pre-ARNm es un proceso clave de la expresión génica que incluye el corte y la poliadenilación del extremo 3’ libre del pre-ARNm. En metazoos, el complejo CstF (Cleavage stimulation Factor) reconoce una secuencia del pre-ARNm rica en U y G/U y permite la estabilización del complejo CPSF (Cleavage Polyadenylation Stimulating Factor) en el sitio de poliadenilación. Hemos descrito la estructura cristalina del dominio N-terminal de una de las tres subunidades de CstF, CstF-50. La estructura ha revelado la organización de la proteína en un dímero compacto y conservado entre las especies. Dos zonas idénticas conservadas se encuentran expuestas a ambos lados de la superficie estructural. Nuestros resultados corroboran así la hipótesis sobre el modelo hexamérico del complejo CstF. CF IA (Cleavage/ polyadenylation Factor IA), el homólogo de CstF en levaduras, interviene en las dos etapas de la maduración 3’. Las bases para la reconstitución del factor CF IA ‘in vitro’ han sido establecidas. Al mismo tiempo, hemos resuelto la estructura del subcomplejo formado por las regiones de interacción de Rna14p y de Rna15p en solución mediante RMN. En el heterodímero, las dos proteínas forman una entidad única a través de la región C-terminal de Rna14p, dominio “monkeytail”, y el dominio “hinge” de Rna15p, quedando las hélices de la dos proteínas entrelazadas. La localización de estos dominios en sus homólogos mamíferos, CstF-77 et CstF-64, sugiere que este tipo de organización está conservada entre las especies.

This diploma thesis deals with the history of Kutná Hora in 1950's. It contains a description of the period between years 1948 - 1960. The period, during which the most important political and cultural changes but also the toughest repressions against the people took place all around the Czechoslovakia (majority of the changes and repressions was caused by the communist leadership). These years were the period of huge political purges and processes, violent collectivization and many other precautions which were only meant to provide the communists with all the power over the country. The main aim of this thesis is to introduce the situation in Kutná Hora during 1950's and to give the reader a complex overview of the local political and cultural background. All the institutions which determined everyday life in Kutná Hora are described in this thesis. The author focuses especially on the activity of The Local National Committee, courts and individual cultural institutions. The author used archive funds, historic press and specialized literature.

The subject of this work is an art group of four painters that was founded in 1959 and named Experiment. Artists of this group - František Dvořák, Radoslav Kutra, Jaroslav Uiberlay and Miloslav Jemelka - were born in the late twenties of the twentieth century. They belonged to the generation of painters, who had the opportunity to study after the second world war. They also played a crucial role in the forming of artistic expression in the sixties in Czechoslovakia. The main effort of these painters was to overcome the uniformity of socialist realism. They intended to return to and evaluate the visual art produced between wars in Czechoslovakia and in Europe. The feeling of vulgarity of descriptive realism prompted many artists to establish art groups in which their ideas and thoughts were formed due to the mutual confrontation. At the turn of the fifties and sixties was established a large number of "creative groups", whose development was possible due to the Union of Czechoslovak visual artists. Although the Union still served as a strict supervisor, it also allowed many young artists to exhibit their work for the first time in public. Creative groups, along with the Experiment, which was rather small, but compact formation, had merit in the overall release of the intricate situation in the Union. The...

The thesis focuses on the construction and symbolic encoding of Prague from 1945 to the late 1950s, with emphasis on the Stalinist era. Based on an analysis of historical texts and architectural projects, the thesis studies the motivations and tactics, which the post-war political and professional elites sought to manifest their own values and ideological principles in the area of the capital city. Through the analysis of historical concepts of "old" and "new" Prague examines the thesis the changing relationship between tradition and modernity in the image of the city. The sociocultural phenomenon of Stalinism is thematized as a specific part of the long process of modernization, which passes through Prague during the first half of the 20th century. The thesis deals also with the attributes that should characterize the "new" socialist Prague and with the ways of using the Soviet patterns and local historical traditions. Keywords: Prague, city, image of the city, architecture, urbanism, memory, heritage, socialist realism, stalinism, 1950s

This diploma thesis is dealing with problems of Judaism during the Second World War in Czech literature, prosaic writings at the turn of the fifties and so called golden sixties of the twentieth century in particular. The thesis provides an analysis of literary output of five Czech writers: the collection of short stories Psí život by Ludvík Aškenazy, novella Bez krásy, bez límce by Hana Bělohradská, novel Krutá léta by František Kafka, the collection of short stories Mí černovlasí bratři by Ladislav Fuks and the collection of short stories Démanty noci by Arnošt Lustig. Theoretical part of this thesis specifies Judaism phenomenon during the Second World War, in the second half of fifties and in the sixties. Practical part pays attention to the subject matter of the Second World War in literature and school education and at the same time brings the analysis of chosen writings. The thesis also provides an analysis of The Framework Education Programme and worksheets as a teaching aid to help teachers and students as well to understand the problems and to achieve their goals given in FEP or didactic principles of interpretation.