Biomimicry is an applied science that derives inspiration for solutions to human problems through the study of natural designs, systems and processes. This thesis represents an investigation into biomimicry and includes the development of a design method based on biomimetic principles that is applied to the design of curved building surfaces whose derived integral structure lends itself to ease of manufacture and construction. <br /><br /> Three design concepts are produced that utilize a selection of natural principles of design outlined in the initial biomimetic investigation. The first design visualizes the human genome as a template on which the process of architectural design and construction can be paralleled. This approach utilizes an organizational structure for design instructions, the adherence to an economy of means, and a holistic linking of all aspects of a design characteristic of the genetic parallel. The advancement of the first design concept is illustrated through the use of a particular form of parametric design software known as GenerativeComponents. The second design concept applies the biomimetic design approach outlined in concept one to the development of ruled surfaces with an integral structure in the form of developable flat sheets. The final concept documents the creation of arbitrary curved surfaces consisting of an integral reinforcing structure in the form of folded sheet chevrons.

This thesis is based on two observations. First, that conventional buildings cause two major losses that involve non-human nature – the loss of native biodiversity and the loss of non-human nature experience for the buildings’ human inhabitants – and that these losses both contribute to a perceived separation between humans and the rest of nature. Second, that there appears to be a growing interest in connecting buildings with nature but there is little agreement on what it actually means to ‘design with nature’. As such, the purpose of this study is two-fold: (1) to describe the meaning of ‘designing with nature’ in current architectural practice and provide a working definition of nature-based design, and (2) to explore how this can be interpreted to encourage human connectedness with non-human nature, while addressing the two major losses mentioned above. It is thus an attempt to reframe the role of building as one that provides for all inhabitants of a site, both human and non. A framework was developed that captures and summarizes the dominant ways in which design draws on nature. The framework emphasizes the importance of using ecosystems not only as models, but foremost as context. The core concepts of the framework can thus be discussed from the perspective of buildings that act like an ecosystem and that interact with their ecosystem, and are described as: ecological sense of place, regenerative ability, ecosystem health, mutually beneficial relationships, context, appropriate management, functions, ecosystem principles, values, patterns, conditions, and adaptations. Although the concepts presented in the framework are themselves not new, the way in which they are organized does contribute a new perspective on the field of nature-based design. In addition to providing a graphic model that summarizes the essence of an evolving field, the research highlights the role of scale and place in linking building design, native biodiversity, nature experience and connectedness with nature. It thus acts as a backdrop on which to bring a discussion of ecological citizenship into the architectural dialogue.

I have organized this paper into four chapters: "The Environmental Situation," "Space and Place," "Art and the Natural Environment," and "Creating Work of My Own." Chapter 1 explains human beings' intrinsic interconnection to the natural environment, outlining why humans should be concerned about the current degraded state of the natural world. Chapter 2 discusses the concepts of space and place. It analyzes how human beings interact with and experience spaces, developing their sense of place - within physical, theoretical, and spiritual realms. It finally illustrates the importance that spaces and places have in humans' lives. Chapter 3 describes the Land Art phenomenon: its development, the different forms within it, and artists producing Land Artworks. The forms and artists included are those that have been inspirational for the development of my own work. It also emphasizes Land Art as a fundamental form for improving humans' relationship with the natural environment and the new realm of eco-feminism that resonates with Land Art ideals. Chapter 4 recounts the development of my art throughout my college career. It describes my work as site-specific, sculptural installations that use natural materials. It also states why this format is the most effective for my senior art thesis project. Focusing mainly on "Ecological Reawakening: organic DNA," it explains the mentality in designing, creating, installing, and completing the work. Overall, Chapter 4 emphasizes the work's two main goals: to demonstrate a new avenue for comprehending humankind's place within earth's environmental spaces, and to advocate for an environmental paradigm shift during the twenty-first century. Finally, Chapter 5 describes the transformation of "Ecological Reawakening: organic DNA" as it developed over time during the spring honors senior thesis course. It details my mentalities in adding living plant matter to the structure, incorporating a stool into the piece, and creating "Evolution," the digital photography composition that documents "Ecological Reawakening" and was included in the Scripps Senior Art Exhibition in the Ruth Chandler Williamson Gallery from May 1 – May 17, 2009.

Les copolymères à blocs amphiphiles peuvent s’auto-assembler sous forme de vésicules,appelées polymersomes. Ces vésicules ont été développées et étudiées depuis de nombreusesannées notamment pour l’encapsulation et la délivrance contrôlée de médicaments. Depuisquelques temps, elles connaissent des applications dans le domaine du biomimétisme cellulaire.Plus robustes que leurs analogues lipidiques (liposomes), les avantages à utiliser lespolymersomes comme mimes synthétiques de cellules biologiques ne sont plus à démontrer.Ainsi, des structures compartimentées à base de polymères ont été développés comme mimesstructurels de cellules. Ces systèmes ont été utilisés comme bioréacteurs, avec la réalisation deréactions chimiques ou enzymatiques en cascade en milieu confiné. Toutefois, l’un desobstacles qu’il reste à franchir est de trouver des moyens simples et efficaces pour déclencherla réaction au sein de ces systèmes. C’est dans ce contexte que s’inscrivent les travaux de cettethèse. Une membrane synthétique asymétrique à base de lipide et polymère a été développée etla méthode d’émulsion-centrifugation a été utilisée pour produire des systèmes compartimentésbiomimétiques. De plus, deux approches différentes ont été suivies pour provoquer la libérationcontrôlée d’espèces encapsulées, l’une utilisant la température et l’autre la lumière. Enfin, desétudes de co-encapsulation de cellules synthétiques (polymersomes) et biologiques au sein demilieux 3D ont été réalisées dans le but d’évaluer leur compatibilité et la possibilité de les cocultiver. / Amphiphilic block copolymers can self-assemble into vesicles, also called polymersomes.These vesicles have been developed and studied for many years especially in the field of drugloading and controlled release. More recently, their use as cell mimics have attracted a lot ofattention, mainly because polymersomes exhibit many advantages in contrast to their lipidicanalogues (liposomes). In such, compartmentalized polymer systems have especially beendeveloped as structural mimics of cells. These systems have found applications as bioreactorsthat can confine cascade chemical or enzymatic reactions. However, a major goal that stillremains to achieve is to find ways to trigger the beginning of these chemical reactions insidethe compartmentalized structures. The work carried out during this PhD thesis was actually totackle this challenge. A synthetic asymmetric lipid – polymer membrane, that mimics themembrane of biological cells was developed and the emulsion-centrifugation protocol wasfollowed to prepare biomimetic compartmentalized structures. In addition, two different waysto control the independent release of multiple species from individual compartments weredeveloped, based on temperature or light activation. Lastly, co-encapsulation of synthetic cells(polymersomes) and biological cells were performed in 3D media with the aim to study theircompatibility for co-culture experiments.

This thesis is based on two observations. First, that conventional buildings cause two major losses that involve non-human nature – the loss of native biodiversity and the loss of non-human nature experience for the buildings’ human inhabitants – and that these losses both contribute to a perceived separation between humans and the rest of nature. Second, that there appears to be a growing interest in connecting buildings with nature but there is little agreement on what it actually means to ‘design with nature’. As such, the purpose of this study is two-fold: (1) to describe the meaning of ‘designing with nature’ in current architectural practice and provide a working definition of nature-based design, and (2) to explore how this can be interpreted to encourage human connectedness with non-human nature, while addressing the two major losses mentioned above. It is thus an attempt to reframe the role of building as one that provides for all inhabitants of a site, both human and non. A framework was developed that captures and summarizes the dominant ways in which design draws on nature. The framework emphasizes the importance of using ecosystems not only as models, but foremost as context. The core concepts of the framework can thus be discussed from the perspective of buildings that act like an ecosystem and that interact with their ecosystem, and are described as: ecological sense of place, regenerative ability, ecosystem health, mutually beneficial relationships, context, appropriate management, functions, ecosystem principles, values, patterns, conditions, and adaptations. Although the concepts presented in the framework are themselves not new, the way in which they are organized does contribute a new perspective on the field of nature-based design. In addition to providing a graphic model that summarizes the essence of an evolving field, the research highlights the role of scale and place in linking building design, native biodiversity, nature experience and connectedness with nature. It thus acts as a backdrop on which to bring a discussion of ecological citizenship into the architectural dialogue. / Applied Science, Faculty of / Architecture and Landscape Architecture (SALA), School of / Graduate

Uno de los más grandes desafíos que tiene la ciudad de Lima en la actualidad es hacer frente al avance de la expansión urbana informal, esto ha generado consecuencias como: desertificación de los valles limeños, incongruencias urbanas y sobre todo un deterioro abismal en los monumentos arqueológicos que son parte de la trama urbana de la ciudad, desde esta perspectiva el proyecto de vivienda comunitaria surge como un elemento unificador, el cual propone una tipología capaz de integrar equilibradamente la vivienda con el patrimonio arqueológico de la ciudad a través de espacios comunitarios (jardines compartidos, huertos y áreas comunes), los cuales al estar estrictamente relacionados a las viviendas dan lugar al desarrollo de un master plan que consolide el entorno como un ecosistema comunitario - cultural sostenible. Asimismo, el proyecto está ligado a criterios de biomimesis, reinterpretando la forma, funcionalidad, espacialidad, atmósfera y pensamiento de un elemento probado por la naturaleza, en este caso las Huacas. Es así, que las viviendas se desarrollan en base a dos módulos bases, los cuales son resultados de una decodificación del elemento natural. Finalmente, el desarrollo de las áreas comunes (equipamiento urbano, jardines compartidos, huertos y áreas comunes de recreación) tienen el objetivo de fortalecer los lazos comunitarios de los usuarios del proyecto con la atmósfera cultural del entorno, a través de un eje central de coexistencia, el cual remata en el Museo de Sitio propuesto en el Master Plan, generando así la interacción necesaria capaz de estimular el desarrollo de la vida comunitaria. / One of the biggest challenges that the city of Lima has is facing the urban informal expansion. This has led to different consequences, such us the desertification of the Lima valleys, urban inconsistencies, and above all, a huge damage on the archeological monuments that conform the urban pattern of the city. From this perspective, the community housing project takes place as a unifying item that proposes a typology. This typology is able to equally integrate the housing with the archeological heritage of the city through the creation of community spaces (gardens, orchards and common areas). These exclusively housing-related areas result in the development of a master plan that consolidates the environment as a sustainable community and cultural ecosystem. Besides, the project is linked to biomimetic criteria, reinterpreting the shape, functionality, speciality, atmosphere and thinking of an element tested by the nature, like the Huacas. In this way, the housing is developed based on a two-modules base, which result from a decoding of a natural element. Finally, the development of the common areas (urban equipment, gardens, orchards, and recreational common areas) have been intended to strengthen the community bonds of the project’s users with the cultural atmosphere of the environment. This can be achieved through a central axis of coexistence, which ends with the Site Museum suggested in the Master Plan, that generates the necessary interaction to stimulate the development of the community life. / Tesis

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