The International Monetary Fund points out that four kinds of financial crisis in the world financial markets currency crisis, external debt crisis, bank crisis and systematic crisis . Taiwan could be happened in bank crisis and could have potentially impaired the economies of Taiwan. That was reason why Government protected banking industry avoiding collapse and bankruptcy. This paper details why Private Equity Fund M&A Taiwan domestic bank and the effects on financial markets. Since 2006 Carlyle Group one of a global private equity investment firm takeover bid for Advanced Semiconductor Engineering Inc (¤é¤ë¥ú¥b¾ÉÅé)--the world's top chip packager for US$5.45 billion- Private Equity Firm had known for Taiwan financial markets. The Government refused the plan due to that takeover bid may weakening the local capital market and leading to an outflow of investment into China. Foreign investment in Taiwan's banking industry is not new, but the acquisition of domestic banks has only become available to Private Equity Fund recently. The domestic banking industry has become a lucrative target for foreign investors not only of the Government has a policy of limiting the quantity of banking branches but also lower P/B in Asia region. Since 1997s, a striking feature in the development of Taiwan banking industry structure is the significant decline in the performance of banks while the steadily increase in the number of bank branches and caused by overbanking in Taiwan. As Taiwan slowly opens its banking industry after second round banking reformation in 2001, global M&A trends also had impacts on Taiwan, foreign financial institutions are increasingly looking to make strategic and financial investments. This paper gives a brief description of the development in the past 10 years, analyzes the driving forces on the merger of financial institutions From this research, we could come to the conclusions as follows: 1. A financial investment in domestic banks is a win-win for the various parties Private equity fund M&A of domestic commercial banks not only a very good source of capital in Taiwan, but also, through the competition of foreign banks, stimulates domestic financial institutions to upgrade operational skills and management, and improve operational efficiency and competitiveness, thus contributing to the upgrading of the financial system. 2. This paper using threshold regression model to find an adequate branch numbers of Commercial Banks industry in Taiwan. We found significant evidence good for the shareholders equity only when the branch numbers are larger than 88. 3. On the view of bank branch, the next target acquired company is Far Eastern International Bank(35 branches) ,Jih Sun Bank(36 branches) , King¡¥s Town Bank(62 branches) ,Taichung Commercial Bank(78 branches).ABN AMRO Bank(Taiwan)M&A Taitung Business Bank, the branches from 5 to 37, not to meet the bank's need for scale economics in Taiwan markets and should be M&A again 4. Private Equity Fund aims to pursue long term total return primarily through investment in equities and equity-related securities but had unique niche in resolving banking risk and corporate governance. also capitalized on the recovery of financial markets after the financial crisis in Taiwan banking indusdry According to experience of Private-Equity Firm to merge to banking industry in Korea Private Equity Fund exit their investments at last within 5-7 years after turned the bank successfully around 5. It's difference type of entering the Taiwan market through the acquisitions of banks, one is strategic investment (e.g.,Citigroup and Standard Chartered) and financial players (e.g., Newbridge Capital, The Carlyle Group).Strategic investment made a goal to construct a plateform to link Taiwan and China

Several reports research the best prediction power of the credit risk models for different industries. The structural models use firm¡¦s information for firms¡¦ structural variables, such as asset value and asset volatility, to determine the time of default, but it suffer from some drawbacks, which represent the main reasons behind their relatively poor empirical performance. It require estimates for the parameters of the firm¡¦s asset value, which is nonobservable. Moody's KMV model is well known and useful among them, but it ignores recovery rate and difference in financial structure and industry. The reduced-form models fundamentally differ from typical structural models in the degree of predictability of the default. Reduced-form models use market data and assume the probability of default is exogenously generated. However, the basel committee for banking supervision proposed that risk is endogenous. The purpose of this paper is using quantile and threshold regression to introduce a new approach which is based on the Moody¡¦s KMV model, the Lu and Kuo ( 2005) and the Altman, Brooks Brady, Resti and Sironi (2005) to the evaluation of the endogenous probability of default and the endogenous recovery rate.

Today, there is an ever-growing demand for compact, and energy autonomous, implantable biomedical sensors. These devices, which continuously collect in vivo physiological data, are imperative in the next generation patient monitoring systems. One of the fundamental challenges in their implementation, besides the obvious size constraints and the tissue-to-electronics biocompatibility impediments, is the efficient means to wirelessly deliver power to them. This work addresses this challenge by demonstrating an energy-autonomous and fully-integrated implantable sensor chip which takes advantage of the existing on-chip photodiodes of a standard CMOS process as photovoltaic (PV) energy-harvesting cells. This 2.5 mm × 2.5 mm chip is capable of harvesting [mu]W’s of power from the ambient light passing through the tissue and performing real-time sensing. This system is also MRI compatible as it includes no magnetic material and requires no RF coil or antennae. In this dissertation, the optical properties of tissue and the capabilities of the CMOS integrated PV cells are studied first. Next, the implementation of an implantable sensor using such PV devices is discussed. The sensor characterizing and the in vitro measurement results using this system, demonstrate the feasibility of monolithically integrated CMOS PV-driven implantable sensors. In addition, they offer an alternative method to create low-cost and mass-deployable energy autonomous ICs in biomedical applications and beyond. / text

Psychologists have long appreciated that many real-world decisions require a balance of expediency and accuracy in gathering evidence. Often the best decisions are made when there is some lingering uncertainty. But how much? Depending on the situation, choosing the right amount of evidence can often be a fine line between making a rash decision and being indecisive. Psychologists have been reluctant to pursue studying peoples' abilities to judge the correct "threshold" for probabilistic decisions. There are two reasons for this: First, the question of a decision threshold, or "when should I stop gathering evidence?" is confounded by the larger issue of how subjects choose and integrate that evidence. Subjects may have a decision threshold that is consistently sub-optimal with respect to a model that does not consider cognitive constraints. However, subjects may actually be choosing the right amount of information given their own cognitive limitations. Second, it has been shown that people often use specific heuristics in making probabilistic decisions. In this case, defining a decision threshold would be largely dependent on the heuristic and task, thus preventing a study of decision thresholds that is widely applicable. The research presented here addresses both of these concerns. I defined a task where the ideal decision threshold is clearly defined, requiring some evidence, but not an exhaustive search. Furthermore, this threshold can be precisely manipulated by changes in the reward structure. Although it is possible to use a "sufficing" or sub-optimal heuristic, subjects are given a significant financial incentive to fully integrate as much evidence as possible. Lastly, and most importantly, a general model of people's cognitive limitations is applied to the traditional normative model. This enhancement allows a more refined study of humans' ability to place their decision threshold according to environmental conditions. / text

Stated simply, this thesis focuses on the relationship between energy and the economy. Using the foundation of King 2010, this analysis expands the scholarship from a U.S. focus to perform Energy Intensity Ratio analysis on forty-four countries for the time period 1978-2010. There are four fuels examined: coal, natural gas, crude oil and electricity. Using both the price and expenditures based Energy Intensity Ratio methods, outputs for each fuel in any applicable sector was determined. In addition, this work compiles an estimate of the total energy expenditures for the majority of the world. By examining the overall expenditures of gross domestic product spent on energy, the data showed two points in time where energy appears to become a constraint on growth. Though this thesis does not answer the question directly as to whether an increase in energy expenditures “causes” an increase in economic growth, or whether an increase in economic growth “causes” an increase in energy expenditures, the research shows that vi there may be a “threshold” effect whereby as energy expenditures become a greater share of output, the ability of economic growth to take place is affected. / text

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Background: Cough Reflex Testing (CRT) has been shown to be useful in the challenging task of identifying silent aspiration (aspiration without a cough response). With the emergence of the routine clinical use of CRT in the acute stroke population, the following clinical conundrum often arises: Does passing a previously failed CRT mean the risk of silent aspiration has resolved? The purpose of this study was to evaluate the association between change in laryngeal cough threshold sensitivity and change in PAS (Penetration Aspiration Scale) score within the acute stage post-stroke. Methods: This was a prospective longitudinal pilot study of 20 acute stroke patients utilizing a Cough Reflex Threshold Test (CRTT) at 0.4M, 0.6M and 0.8M citric acid concentrations and Fiberoptic Endoscopic Evaluation of Swallowing (FEES). A cough response threshold was obtained from the CRTT and a PAS (penetration aspiration scale) score from FEES. Inclusion criteria required a PAS score of 4 or above on preliminary FEES or impaired CRT threshold as defined by weak or failed cough test result at 0.8M citric acid concentration. Both test methods were repeated every four days for 20 days or until the participant no longer aspirated/penetrated and had a normal result on CRTT on two consecutive assessment sessions. Agreement between changes in the two tests was evaluated using the Cohen’s Kappa statistic. Results: Eighteen of the twenty participants in this study aspirated on initial assessment, ten of which were silent. One participant continued to aspirate at study completion. On initial assessment eleven participants had a C2 response threshold at 0.4M citric acid concentration and three participants failed to reach threshold at 0.8M citric acid concentration. At study completion, 18 participants had a C2 response threshold at 0.4M citric acid concentration and one participant failed to reach threshold at 0.8M citric acid concentration. During the study, sixty-six re-assessments took place; there were fifteen incidences of improved cough response threshold on re-assessment and thirty-one incidences of improved PAS score. There was no significant agreement between improved laryngeal cough reflex threshold and improved PAS score during the acute stage Kappa = 0.0598 (p <.0.574), 95% CI (- 0.1496- 0.2692). Conclusion: Significant limitations of this study included small data set and potential flooring effect of the CRT. Due to the limitations of this study, no conclusions can be made as to the appropriateness of reinstating oral intake based on passing a previously failed CRT.

In online shopping buyers do not have enough information about sellers and cannot inspect the products before purchasing them. To help buyers find reliable sellers, online marketplaces deploy Trust and Reputation Management (TRM) systems. These systems aggregate buyers’ feedback about the sellers they have interacted with and about the products they have purchased, to inform users within the marketplace about the sellers and products before making purchases. Thus positive customer feedback has become a valuable asset for each seller in order to attract more business. This naturally creates incentives for cheating, in terms of introducing fake positive feedback. Therefore, an important responsibility of TRM systems is to aid buyers find genuine feedback (reviews) about different sellers. Recent TRM systems achieve this goal by selecting and assigning credible advisers to any new customer/buyer. These advisers are selected among the buyers who have had experience with a number of sellers and have provided feedback for their services and goods. As people differ in their tastes, the buyer feedback that would be most useful should come from advisers with similar tastes and values. In addition, the advisers should be honest, i.e. provide truthful reviews and ratings, and not malicious, i.e. not collude with sellers to favour them or with other buyers to badmouth some sellers. Defining the boundary between dishonest and honest advisers is very important. However, currently, there is no systematic approach for setting the honesty threshold which divides benevolent advisers from the malicious ones. The thesis addresses this problem and proposes a market-adaptive honesty threshold management mechanism. In this mechanism the TRM system forms a feedback system which monitors the current status of the e-marketplace. According to the status of the e-marketplace the feedback system improves the performance utilizing PID controller from the field of control systems. The responsibility of this controller is to set the the suitable value of honesty threshold. The results of experiments, using simulation and real-world dataset show that the market-adaptive honesty threshold allows to optimize the performance of the marketplace with respect to throughput and buyer satisfaction.

Persistence is one of the core criteria in chemical exposure and hazard assessment. It is often defined as the half-life for the removal of a chemical from a specified environment by transformation. Chemicals with long transformation half-lives may pose high risks for wildlife or humans and be subject to long-range transport to remote areas. It is challenging to measure persistence directly in the field in view of the complexity of the natural environment and spatial and temporal variability in environmental conditions that may affect degradation. The mass balance approach is the most commonly used method for field measurement of persistence. In this thesis an alternative to the traditional mass balance approach that uses benchmarking is proposed and evaluated using models and field application. The benchmarking approach compares the relative behavior of chemicals, rather than measuring the absolute value of a property. The unknown property (persistence in this thesis) of test chemicals can be estimated by comparison against another chemical for which this property is known. In Paper I, the potential of benchmarking to measure persistence in the field was evaluated by modeling. A framework for applying benchmarking to measure persistence in the field was developed. Lake systems with hydraulic residence times of the order of months were identified as appropriate field sites to measure the persistence of chemicals that are close to the regulatory thresholds, which are also on the scale of months. Field studies in two Swedish lakes were conducted. Both are shallow lakes, whereas Norra Bergundasjön (Paper II) has a longer residence time (four months) than Boren (one to two months; Paper III). In Paper II the benchmarking approach was tested to measure the persistence of a group of chemicals that were expected to stay in the water phase. Acesulfame K (artificial sweetener) without observable degradation in the lake was used as the benchmark chemical. The persistence of 9 pharmaceuticals and one X-ray contrast agent was measured to range from &lt;1-2 days (ketoprofen) to 580-5700 days (carbamazepine). The results obtained using the benchmarking approach agreed well with the mass balance approach, indicating that the benchmarking approach can be a valid and useful method to measure persistence in the field. In Paper III the seasonality in chemical persistence was investigated by benchmarking. The seasonal difference in chemical persistence was found to be largest between spring and autumn. The persistence of 5 chemicals in spring were lower than in autumn, mainly attributed to lower temperature and less sunlight in autumn. The spatial variation of the persistence of chemicals was observed by comparing the persistence of chemicals in spring in the two lakes. Thus benchmarking is a useful tool to study the temporal and spatial variation of persistence in the real environment.   Paper IV explores the potential of benchmarking thoroughly and the application of benchmarking in a regulatory context. Benchmarking could facilitate more field measurements of persistence, leading to a better understanding of the temporal and spatial variability of persistence in various environments and a basis for lab-to-field extrapolation. Besides quantitative estimation of persistence in the field, benchmarking can be applied to determine the relative magnitude of persistence, called threshold benchmarking which could be a valuable tool in regulatory processes. / <p>At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 3: Submitted. Paper 4: Manuscript.</p>

Absolute quantification of the 3D distribution of a radionuclide within a patient has been one of the greatest challenges of nuclear medicine. This is due to the fact that nuclear medicine images are degraded by several factors, which limit the quantitative ability of this modality. Quantitative SPECT has wide applications in many areas in nuclear medicine from radiation dosimetry calculations to clinical applications. It has use in image analysis studies to extract information about areas, volumes, and/or amounts of radioactivity in specific regions of interest. The information that derived from these studies is then applied to estimate radiation dosimetry, volumes or to aid in clinical diagnoses. Absolute quantitation means precise and accurate measurements of volume and the amount of radioactivity in a specific region of interest. For absolute quantitation of volume the measurements can be expressed in cubic centimetres, for radioactivity in μCi or Bq. Quantitation of organ volumes using planar imaging technique is a procedure often performed in nuclear medicine but face difficulties due to structure containing radioactivity, which overlie or underlie the organ of interest. SPECT overcomes these difficulties since it is able to separate these structures in the reconstructed images, which have higher contrast than planar images. In the theoretical part of this work, there is a description of the operation and the characteristics of a gamma camera system. Following that, there is a mention to the quality control procedures of the system both for planar and SPECT techniques. Also, there is an extended discussion of the factors that affect to the image quantitation and the corrections that must be applied in order to achieve better volume and activity estimation. At the end of the theoretical part, there is a presentation of procedure for volume and activity quantitation on I-131 sources using threshold technique. In the practical part, there is a study on volume and activity quantitation for I-131 sources with volumes 0.5,1,5,8,10,20 and activities from 300 to 529 μCi using threshold technique. The practical part of this work was performed in the department of Nuclear Medicine of the “THEAGENION” Cancer Institute of Thessaloniki (Greece), with association with the department of Medical Physics. / Η απόλυτη ποσοτικοποίηση της κατανομής ενός ραδιοφαρμάκου στον ασθενή, είναι μια από τις μεγαλύτερες προκλήσεις στην πυρηνική ιατρική, καθώς οι εικόνες από τη γ-κάμερα υποβαθμίζονται από διάφορους παράγοντες, που περιορίζουν την ικανότητα ποσοτικοποίησης. Η ποσοτικοποίηση μέσω SPECT έχει πολλές εφαρμογές στην πυρηνική ιατρική, στο διαγνωστικό τομέα και στο θεραπευτικό στη δοσιμετρία. Χρησιμοποιείται κατά την ανάλυση των εικόνων με σκοπό τον προσδιορισμό όγκων και την μέτρηση ραδιενέργειας σε συγκεκριμένες περιοχές ενδιαφέροντος. Η απόλυτη ποσοτικοποίηση σημαίνει σαφή και όσο το δυνατόν, ακριβή μέτρηση όγκου και ραδιενέργειας σε κάποια περιοχή ενδιαφέροντος. Ο όγκος μπορεί να εκφραστεί σε κυβικά εκατοστά και η ραδιενέργεια σε μCi ή Bq. Η ποσοτικοποίηση του όγκου των οργάνων, χρησιμοποιώντας planar τεχνικη, είναι μια διαδικασία που χρησιμοποιείται συχνά στην πυρηνική ιατρική. Παρ’όλα αυτά αντιμετωπίζει δυσκολίες λόγω των δομών, που βρίσκονται πάνω και κάτω από την περιοχή ενδιαφέροντος, και περιέχουν ραδιενέργεια. Το SPECT αντιμετωπίζει αυτές τις δυσκολίες, αφού έχει τη δυνατότητα να ξεχωρίσει αυτές τις δομές, στις εικόνες που έχουν ανακατασκευαστεί, και να τις παρουσιάσει με μεγαλύτερη αντίθεση από την planar τεχνική. Στο θεωρητικό μέρος της εργασίας γίνεται περιγραφή των χαρακτηριστικών και της λειτουργίας του απεικονιστικού συστήματος της γ-camera. Ακολουθεί η περιγραφή των διαδικασιών ποιοτικού έλεγχου του συστήματος τόσο για την Planar όσο και για την SPECT τεχνική. Στη συνέχεια, γίνεται παρουσίαση της μεθόδου ποσοτικοποίησης όγκου και ραδιενέργειας, στην περίπτωση πηγών Ι-131, εφαρμόζοντας την τεχνική κατωφλίου, ανάλυση των παραγόντων που την επηρεάζουν, καθώς και των διορθώσεων, που πρέπει να γίνονται, ώστε να επιτυγχάνεται η όσο το δυνατόν μεγαλύτερη ακρίβεια. Στο πειραματικό μέρος της εργασίας γίνεται εφαρμογή της παραπάνω μεθόδου σε πηγές Ι-131, όγκου 0.5-20 ml ραδιενέργειας 300-529μCi και σύγκριση των αποτελεσμάτων. Η συγκεκριμένη εργασία εκπονήθηκε στο Τμήμα Πυρηνικής Ιατρικής του ΑΝΘ ‘’ΘΕΑΓΕΝΕΙΟ’’ σε συνεργασία με το Τμήμα Ιατρικής Φυσικής του Νοσοκομείου.