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v, 137 p. : ill., plates ; 26 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Physics, 1974

Thesis (Ph.D.) -- University of Adelaide, Dept. of Physics, 1974.

Dissertation submitted in compliance with the requirements for the Master's Diploma in Technology: Electrical Engineering (Light Current), Technikon Natal, 1987. / In the gold mining industry, one of the significant physical properties of the mineral slurry is its density and it is important to be able to measure this parameter in most processes. There are many techniques for determining the density of fluids, but because of the hostile, abrasive nature of mineral slurry, very few of these are suitable, This dissertation describes the deveiopment, construction and testing of a portable, ultrasonic, density measuring instrument. The instrument uses an ultrasonic transducer as the primary measuring element, and system operation is based on the fact that the driving impedance of the transducer varies with changes in the physical properties, and hence the characteristic impedance, of the surrounding medium into which the ultrasonic energy is being transferred. The technique may a-Lao be used to measure the relative concentrations of two liquids in a mixture or emulsion, provided that the characteristic impedances of the liquids are sufficiently dissimilar. The electronic circuitry is fairly straightforward, consisting essentially of an oscillator, driving circuit for the transducer and a voltage monitor to provide a d.c. voltage proportional to the impedance of the transducer, and hence to the density of the surrounding medium. Most of the research has been concentrated on the probe design, as the type of transducer, the type and thickness of facing material and the method of construction all contribute to the sensitivity of the instrument. A design of probe assembly has been developed that may be used for both slurry density measurement and the measurement of the ratio of aqueous to organic liquids in emulsion. / M

M. S.

M.S.

Pulsed ultrasound Doppler velocimetry proved to be capable of measuring velocities accurately (relative error less than 0.5 percent). In this research, the limitations of the method are investigated when measuring: in channels with a small thickness compared to the transducer diameter, at low velocities and in the presence of a flow reversal area. A review of the fundamentals of pulsed ultrasound Doppler velocimetry reveals that the accuracy of the measured velocity field mainly depends on the shape of the acoustic beam through the flow field and the intensity of the echo from the incident particles where the velocity is being measured. The ultrasonic transducer turned out to be most critical component of the system. Fundamental limitations of the method are identified. With ultrasonic beam measurements, the beam shape and echo intensity is further investigated. In general, the shape of the ultrasonic beam varies depending on the frequency and diameter of the emitter as well as the characteristics of the acoustic interface that the beam encounters. Moreover, the most promising transducer to measure velocity profiles in small channels is identified. Since the application of pulsed ultrasound Doppler velocimetry often involves the propagation of the ultrasonic burst through Plexiglas, the effect of Plexiglas walls on the measured velocity profile is analyzed and quantified in detail. The transducers ringing effect and the saturation region caused by highly absorbing acoustic interfaces are identified as limitations of the method. By comparing measurement results in the small rectangular channel to numerically calculated results, further limitations of the method are identified. It was not possible to determine velocities correctly throughout the whole channel at low flow rates, in small geometries and in the flow separation region. A discrepancy between the maximum measured velocity, velocity profile perturbations and incorrect velocity determination at the far channel wall were main shortcomings. Measurement results are improved by changes in the Doppler angle, the flow rate and the particle concentration. Suggestions to enhance the measurement system, especially its spatial resolution, and to further investigate acoustic wave interactions are made.

L’imagerie photoacoustique est une nouvelle modalité couplant imagerie optique et échographie. Non invasive, elle permet d’imager des absorbeurs optiques à quelques centimètres de profondeur et avec la résolution de l’échographie. La réception des signaux photoacoustiques se faisant à l’aide d’un échographe clinique, cette modalité hybride vient compléter idéalement l’imagerie ultrasonore en apportant des informations fonctionnelles aux informations structurelles de l’échographie. Ces atouts en font une technique d’imagerie très prometteuse pour la clinique, notamment comme outil de diagnostic précoce. Ce travail de thèse a pour objectif principal la mise en place des outils nécessaires au développement de cette thématique de recherche d’un point de vue expérimental, à des fins cliniques. En particulier, l’apport de l’imagerie photoacoustique pour le diagnostic de plaques d’athérome vulnérables est investigué sur fantômes, grâce à un protocole original. Pour cela un système d’imagerie photoacoustique a été développé et caractérisé à l’aide de fantômes bimodalités élaborés spécifiquement pour les différentes études présentées. Gardant à l’esprit le transfert de cette technique en clinique, un échographe clinique de recherche est utilisé et différentes spécificités du banc nécessaires à l’imagerie in vivo et au diagnostic médical ont été investiguées. Cela implique une amélioration des performances de détection du signal photoacoustique, notamment en termes de sensibilité et de contraste. Pour cela, une nouvelle technologie de sondes ultrasonores est évaluée en la comparant aux sondes actuellement utilisées. De plus, une excitation multispectrale permet l’identification de différents éléments présents dans les tissus. L’aspect temps-réel de l’échographie fait de cette modalité une des plus utilisées pour le diagnostic clinique. Par conséquent, une imagerie photoacoustique voire bimodale en temps réel présente un réel atout pour son transfert clinique. Cette possibilité est investiguée sur le système mis en place au cours de la thèse grâce à un échographe de recherche et une étude sur fantômes. Enfin, une autre contribution de ce travail concerne l’apport de l’imagerie photoacoustique à la caractérisation de la vulnérabilité de la plaque d’athérome. Cette indication de vulnérabilité est obtenue en déterminant la composition de la plaque, en particulier en termes de lipides. L’imagerie photoacoustique, couplée à l’échographie, peut permettre cette identification. Pour étudier cette possibilité, nous nous sommes intéressés à l’artère carotide pour son accessibilité et la place qu’elle occupe dans le diagnostic de la plaque d’athérome en échographie et échographie Doppler. Un protocole original a été élaboré afin d’apporter l’excitation optique au plus près de la carotide. La faisabilité de cette approche est investiguée sur un fantôme conçu spécifiquement pour cette étude et les résultats préliminaires sont présentés. / Photoacoustic (PA) imaging is a new imaging modality coupling ultrasound and optical imaging. This non-invasive technique achieves a penetration depth up to several centimeters with optical contrast and ultrasound resolution. Moreover, since PA signals are detected with a US scanner, PA imaging ideally complete US imaging, adding functional information to the structural ones brought by echography. Therefore PA imaging looks very promising, specifically as a clinical early diagnosis tool. The main objective of this thesis is to set up the required tools to develop the experimental investigation for this research topic and, in particular, to apply it to the diagnosis of vulnerable atheroma plaques. A PA imaging system has been set up and characterized using specifically designed bimodal phantoms. Additional studies have been made to evaluate the suitability of this imaging platform for clinical imaging. For example, in vivo imaging requires better signal detection in terms of contrast and sensitivity, achieved thanks to a new probe technology, and the identification of tissue composition using a multispectral optical excitation. Finally, PA and even PAUS real time imaging is a real asset for medical diagnosis that has been investigated. Another contribution of this work is the use of PA imaging to characterized atheroma plaques vulnerability with the detection of lipids inside these plaques. PA imaging, coupled to echography, can address this need. To study this possibility, the carotid artery has been considered and a new protocol has been elaborated to bring the optical excitation very close to this artery. A feasibility study has been realized on a specific phantom and the preliminary results are presented.

The ability to numerically determine the received signal in an ultrasound pulse-echo system is very important for the development of new ultrasound applications, such as tissue characterization, complex object recognition, and identification of surface topology. The output signal from an ultrasound pulse-echo system depends on the transducer geometry, reflector shape, location and orientation, among others, therefore, only by numerical modeling can the output signal for a given measurement configuration be predicted. This thesis concerns about the numerical modeling and optimal design of annular array based ultrasound pulse-echo system for object recognition. Two numerical modeling methods have been implemented and evaluated for calculating received signal in a pulse-echo system. One is the simple, but computationally demanding Huygens Method and the other one is the computationally more efficient Diffraction Response for Extended Area Method (DREAM). The modeling concept is further extended for pulse-echo system with planar annular array. The optimal design of the ultrasound pulse-echo system is based on annular array transducer that gives us the flexibility to create a wide variety of insonifying fields and receiver characteristics. As the first step towards solving the optimization problem for general conditions, the problem of optimally identifying two specific reflectors is investigated. Two optimization methods, the straightforward, but computationally intensive Global Search Method and the efficient Waveform Alignment Method, have been investigated and compared.

"Abstract Conventional ultrasound imaging systems use array transducers for focusing and beam steering, to improve lateral resolution and permit real-time imaging. This thesis research investigates a different use of array transducers, where the acoustic field and the receiver characteristics are designed such that the energy of the output signal from targets of a specified geometry is maximized. The output signal is the sum of the received signals obtained using all the possible combinations of transducer array elements as transmitter and receiver. This work is based on annular array transducers, but is applicable for any array configuration. The first step is the development of software for the efficient modeling of the wave interaction between transmitted field and target, and between the transducer and receiver field. Using this software, we have calculated the received signal for each combination of an array element as transmitter and the same or another array element as receiver, leading to an N x N received signal matrix for an N element array transducer. A waveform optimization algorithm is then implemented for the purpose of determining the set of delays for the individual array elements, which maximizes the energy of the sum of the received signals. In one implementation of this algorithm, the received signal with the maximum energy is considered as a reference signal, and specific delays are applied to the other signals so that any two signals produce a maximum correlation. This leads to an N x N delay matrix, which, however, is not readily implemented in a practical real-time system, which uses all the elements in an array transducer simultaneously to customize acoustic fields. Hence, the values in this delay matrix are fed into a linear programming optimizer tool to obtain a set of delay values, which makes its implementation practical. The optimized set of delays thus obtained is used to maximize the energy of the received signal for a given transducer and target geometry and hence to enhance the reflectivity of that target. It is also important to check the robustness of the optimized set of delays obtained above, for a given target geometry. Robustness refers to the sensitivity of the optimization to variation in target geometry. This aspect is also evaluated as a part of this thesis work."