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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

先驗資訊之運用與變異成份之推定

張正奇, Zhang, Zheng-Qi Unknown Date (has links)
在一般混合效應的模式中, 當變異成份的比值知道時, 我們將討論變異成份的推定 , 本文中都將假設它是和固定效應獨立。LaMotte 在常態分配的假設下提出在二次形式 中最小均方差的推定量(MIMSQE)。在這篇論文中, 將提出兩個方法同樣的可得到MIM- SQE,第一, 在常態假設下, 利用加比重的最小平方法的不偏推定量, 然後為了得到較 小的均方差, 得到收縮的推定量, 此結果和LaMotte 所提的MIMSQE一樣, 另外, 利用 殘差(residuals )的元素的平方項和互相乘積項形成一個向量, 然後此向量之期望值 為變異成份的線性變換, 可以得到最合適的線性推定量, 為變異成份在原來模式中之 MIMSQE。
2

基於Penalized Spline的信賴帶之比較與改良 / Comparison and Improvement for Confidence Bands Based on Penalized Spline

游博安, Yu, Po An Unknown Date (has links)
迴歸分析中,若變數間有非線性(nonlinear)的關係,此時我們可以用B-spline線性迴歸,一種無母數的方法,建立模型。Penalized spline是B-spline方法的一種改良,其想法是增加一懲罰項,避免估計函數時出現過度配適的問題。本文中,考慮三種方法:(a) Marginal Mixed Model approach, (b) Conditional Mixed Model approach, (c) 貝氏方法建立信賴帶,其中,我們對第一二種方法內的估計式作了一點調整,另外,懲罰項中的平滑參數也是我們考慮的問題。我們發現平滑參數確實會影響信賴帶,所以我們使用cross-validation來選取平滑參數。在調整的cross-validation下,Marginal Mixed Model的信賴帶估計不平滑的函數效果較好,Conditional Mixed Model的信賴帶估計平滑函數的效果較好,貝氏的信賴帶估計函數效果較差。 / In regression analysis, we can use B-spline to estimate regression function nonparametrically when the regression function is nonlinear. Penalized splines have been proposed to improve the performance of B-splines by including a penalty term to prevent over-fitting. In this article, we compare confidence bands constructed by three estimation methods: (a) Marginal Mixed Model approach, (b) Conditional Mixed Model approach, and (c) Bayesian approach. We modify the first two methods slightly. In addition, the selection of smoothing parameter of penalization is considered. We found that the smoothing parameter affects confidence bands a lot, so we use cross-validation to choose the smoothing parameter. Finally, based on the restricted cross-validation, Marginal Mixed Model performs better for less smooth regression functions, Conditional Mixed Model performs better for smooth regression functions and Bayesian approach performs badly.
3

基因晶片實驗其樣本數之研究 / Sample Size Determination in a Microarray Experiment

黃東溪, Huang, Dong-Si Unknown Date (has links)
微陣列晶片是發展及應用較為成熟的生物晶片技術。由於微陣列實驗程序複雜,故資料常包含多種不同來源的實驗誤差,為了適當的區分實驗中來自處理、晶片及基因的效應,我們提出混合效應變異數分析模型來調整系統誤差。針對各基因在不同實驗環境的差異性假設檢定問題,利用最小平方法推導出點估計以及對應的檢定統計量。本研究介紹多重檢定問題中的族型一誤差,並證明在此模型下,Sidak調整法為適當的多重檢定方法。在給定族型一誤差率的顯著水準,利用檢定力的公式,運算出在預設檢定力的最低水準下所需最小樣本(晶片)數。最後我們透過電腦模擬,以蒙地卡羅法來估計檢定力與族型一誤差率,由模擬結果發現,採用此最小樣本數結果,其檢定力可達到預期的水準以上,並且其族型一誤差率皆適當地控制在顯著水準以內。
4

資本資產定價模型與三因子模型之分析與比較 / Some Aspects about the Capital Asset Pricing Model and Three-factor Model

廖士仁, Liao, Shih-Jen Unknown Date (has links)
資本資產定價模型已被廣泛使用於分析股票風險與要求報酬率之間的關係。然而,個別股票風險Beta是否足以解釋其報酬,也受到愈來愈多的質疑。Fama和French在1993年提出額外兩個因子來解釋股票報酬。我們將應用資本資產定價模型和三因子模型來分析1963年7月至2002年12月之美國的三大股票交易所上市公司。藉由一次改變分析過程中的一部分,以觀察參數估計值是否穩定。結果發現Beta_HML總是顯著且最為穩定,而Beta_SMB並不顯著。Beta經常顯著,但變動情況較大。另外,我們將考慮個別股票本身的變異,亦即將隨機效果納入考量。 / The Capital Asset Pricing Model (CAPM) has been widely used to analyze the relationship between risk and required rate of return on a stock, while it is doubted that individual stock's risk Beta has enough explanatory power for it's returns. Fama and French (1993) proposed two more factors to help explaining stock returns. We use the CAPM and the three-factor model to analyze listed companys in American stock exchanges, during the period from July 1963 to December 2002. We change part of the analyzing process a time to see if the estimates of the parameters are stable. The risk-premium Beta_HML is always significant and it performs most stable, while another risk-premium Beta_SMB is never significant. Beta is usually significant but it varies. Furthermore, we take within-stock variation into account, so random effects are considered.

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