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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 21 to 29 of 29 (0.008 seconds)| 21 |
Spatio-temporal Transformation OfKoca, Feray 01 February 2012 (has links) (PDF)
&lsquo / Bag&rsquo / settlements have been a part of dynamic spatial systems, which seasonally depend on and reciprocally interact with Anatolian towns throughout centuries. This thesis presents the transforming setting of &lsquo / bag&rsquo / settlements related to changing values and meanings through an ontological assessment. Therefore, the thesis assumes that the main values of spatial organization, farmland pattern, ecological formation, settlement character, socio-cultural structure and lifestyle of the inhabitants constitute the unique entity of &lsquo / bag&rsquo / settlements.
In time, the pressures of changing socio-economic conditions have destroyed the interaction between Anatolian towns and &lsquo / bag&rsquo / settlements. The thesis explains the changing role of &lsquo / bag&rsquo / settlements, changing and conflicting land uses and the loss of unique &lsquo / bag&rsquo / character in the case of Mugla-Karabaglar.
Karabaglar is a &lsquo / bag&rsquo / settlement in the southwestern Turkey, where Mugla town residents live seasonally. It is a third grade natural site, the unique character, the natural and cultural assets and the lifestyle of which must be preserved. However, with transformation of the main values, meanings and practices, Karabaglar could no longer perpetuated its initial existence of being. Karabaglar is significant for two reasons: it has natural and cultural beings that need to be conserved, and as it still goes through a transformation process.
The master&rsquo / s thesis of the author evaluated conservation plan of Karabaglar. Differently, this doctoral thesis evaluates the dynamics of the spatio-temporal transformation process in Karabaglar. It presents the changing role and significance of Karabaglar within the town-country continuum. This situation brings forward the conservation problematic of the character, landscape and uniqueness of Karabaglar. Within this respect, the thesis contributes to the literature of &lsquo / bag&rsquo / settlements in terms of defining their being and changing role throughout the history.
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Die Personifikation des BösenGrüttner, Konrad 16 December 2013 (has links) (PDF)
Der Begriff "Böse" ist seinem Bedeutungsumfang nach derart allumfassend, dass es unmöglich erscheint, sich diesem substanziell zu nähern. Die Arbeit versucht daher, das Phänomen des Bösen über seine Personifikationen zu erfassen und diese anhand begriffsgeschichtlicher Methoden aufzuarbeiten. Dabei steht das Zeitalter der Aufklärung im Zentrum der Analyse, da sich in jener Epoche ein elementarer Wandel vollzog, der das bis ins 18. Jh. hinein religiös geprägte Bild des Bösen ins Reich der Mythen und Legenden verbannte, ohne jedoch seine Personifikation, den Teufel, gänzlich zu vernichten.
Ausgehend von diesem wichtigen Schritt in der Geschichte des Abendlandes entwickelt die Arbeit einen roten Faden der Kulturgeschichte des Bösen, der sich von den biblischen Anfängen bis hin zu den heute geläufigen Vorstellungen zieht. Damit wird verdeutlicht, inwieweit die religiöse Vorstellung des Teufels ein Paradigma bilden konnte, welches epochenübergreifende Geltung gewann.
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Development of a Multilayered Association Polymer System for Sequential Drug DeliveryChinnakavanam Sundararaj, Sharath Kumar 01 January 2013 (has links)
As all the physiological processes in our body are controlled by multiple biomolecules, comprehensive treatment of certain disease conditions may be more effectively achieved by administration of more than one type of drug. Thus, the primary objective of this research was to develop a multilayered, polymer-based system for sequential delivery of multiple drugs. This particular device was designed aimed at the treatment of periodontitis, a highly prevalent oral inflammatory disease that affects 90% of the world population. This condition is caused by bacterial biofilm on the teeth, resulting in a chronic inflammatory response that leads to loss of alveolar bone and, ultimately, the tooth. Current treatment methods for periodontitis address specific parts of the disease, with no individual treatment serving as a complete therapy.
The polymers used for the fabrication of this multilayered device consists of cellulose acetate phthalate (CAP) complexed with Pluronic F-127 (P). After evaluating morphology of the resulting CAPP system, in vitro release of small molecule drugs and a model protein was studied from both single and multilayered devices. Drug release from single-layered CAPP films followed zero-order kinetics related to surface erosion property of the association polymer. Release studies from multilayered CAPP devices showed the possibility of achieving intermittent release of one type of drug as well as sequential release of more than one type of drug. Mathematical modeling accurately predicted the release profiles for both single layer and multilayered devices. After the initial characterization of the CAPP system, the device was specifically modified to achieve sequential release of drugs aimed at the treatment of periodontitis. The four types of drugs used were metronidazole, ketoprofen, doxycycline, and simvastatin to eliminate infection, inhibit inflammation, prevent tissue destruction, and aid bone regeneration, respectively. To obtain different erosion times and achieve appropriate release profiles specific to the disease condition, the device was modified by increasing the number of layers or by inclusion of a slower eroding polymer layer. In all the cases, the device was able to release the four different drugs in the designed temporal sequence. Analysis of antibiotic and anti-inflammatory bioactivity showed that drugs released from the devices retained 100% bioactivity.
Following extensive studies on the in vitro sequential drug release from these devices, the in vivo drug release profiles were investigated. The CAPP devices with different release rates and dosage formulations were implanted in a rat calvarial onlay model, and the in vivo drug release and erosion was compared with in vitro results. In vivo studies showed sequential release of drugs comparable to those measured in vitro, with some difference in drug release rates observed. The present CAPP association polymer-based multilayer devices can be used for localized, sequential delivery of multiple drugs for the possible treatment of complex disease conditions, and perhaps for tissue engineering applications, that require delivery of more than one type of biomolecule.
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A New Census Geography For Turkey Using Geographic Information Systems A Case Study On Cankaya District, AnkaraKirlangicoglu, Cem 01 June 2005 (has links) (PDF)
Today, population census results are not only fundamental for population counting but also for providing various information to many organizations and people who make research and take decisions about human-related issues. However, statistics produced on the basis of administrative divisions in Turkey are inadequate to meet the needs of most
In this study, a new census geography is aimed for Turkey using Geographic Information Systems and Multi Criteria Decision Making methodologies. This new census geography is for statistical purposes only, independent from legal boundaries and generated by the concept of small area statistics. New rules and methodologies are created by taking the United States and the United Kingdom systems as models to reach to the main aim, and then they are applied on a case study area, Ç / ankaya District in Ankara. Through this application process, firstly all the collected graphical and nongraphical raw data are geo-referenced and combined in a common geodatabase. Secondly, this geodatabase is used to understand the differentiation of quality of life indicators across the case study area. This pattern is then used to draw the boundaries of small statistical units of the new census geography in terms of the previously defined population sizes. In conclusion, a nationwide standard census geography hierarchy, which ranges between national level at the top and block level at the bottom, is proposed for use in 2010 Population Census and afterwards.
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Correlacao angular gama-gama para transicoes nos nucleos de Te-127 e Te-129SOUZA, MARISTELA O.M.D. de 09 October 2014 (has links)
Made available in DSpace on 2014-10-09T12:31:38Z (GMT). No. of bitstreams: 0 / Made available in DSpace on 2014-10-09T14:01:05Z (GMT). No. of bitstreams: 1
02286.pdf: 3044750 bytes, checksum: 753f2e5a876a0a848f90cf7bcb06b0e5 (MD5) / Tese (Doutoramento) / IPEN/T / Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
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Correlacao angular gama-gama para transicoes nos nucleos de Te-127 e Te-129SOUZA, MARISTELA O.M.D. de 09 October 2014 (has links)
Made available in DSpace on 2014-10-09T12:31:38Z (GMT). No. of bitstreams: 0 / Made available in DSpace on 2014-10-09T14:01:05Z (GMT). No. of bitstreams: 1
02286.pdf: 3044750 bytes, checksum: 753f2e5a876a0a848f90cf7bcb06b0e5 (MD5) / Tese (Doutoramento) / IPEN/T / Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
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Einfluss von microRNAs auf die Sensibilität von kolorektalen Tumorzellen gegenüber einer 5-FU-basierten Radiochemotherapie / Influence of microRNA on the sensivity of colorectal cancer cells on a 5-FU-based radiochemotherapyTemplin, Robert Hans-Joachim 18 September 2019 (has links)
No description available.
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論語鄭玄注匯輯楊偉強 January 1987 (has links)
University of Macau / Faculty of Social Sciences and Humanities / Department of Chinese
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Stable isotope investigations on speleothems from different cave systems in Germany. / Stabile Isotopen-Untersuchungen an Speläothemen aus verschiedenen Höhlensystemen in Deutschland.Nordhoff, Peter 13 June 2005 (has links)
No description available.
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