This thesis is concerned with the structure, analysis and numerical solution of the mathematical models used to estimate the transmission dynamics of the Human Immunodeficiency Virus (HIV)) the causative agent of Acquired Immune Deficiency Syndrome (AIDS). Investigations show that the devised deterministic mathematical models in term of system of first-order non-linear ordinary differential equations (ODEs) follow the stochastic nature of the problem at any time. In this thesis a generic form of the deterministic mathematical models is introduced which mirrors the transmission dynamics of HIV/AIDS in populations with different states of affairs, which leads to the division of large-scale and complex mathematical models. When analysing and;or solving a large-scale system of ODEs numerically, the key element in speeding up the process is selecting the maximum possible time step. This work introduces some new techniques used to estimate the maximum possible time step, avoiding the appearance of chaos and divergence in the solution when they are not features of the system. The solution to these mathematical models are presented graphically and numerically, aiming to identify the effect of the anti-HIV therapies and sex education in controlling the disease. The numerical results presented in this thesis indicate that lowering the average number of sexual partners per year is more effective in controlling the disease than the current anti-HIV treatments. For the purpose of this study the mathematical software 'Mathematica 3.0' was used to solve the system of differential equations, modelling HIV/AIDS propagation. This package also provided the graphical detail incorporated in the thesis.

Thesis advisor: Penelope Ismay / In this thesis, I examine the history of the U.S. military’s stance on homosexual and bisexual service personnel and the political and cultural influences that changed this stance. Even though the military held a largely anti-homosexual attitude for much of its history, it was only during the AIDS epidemic of the 1980s that the military declared itself as antigay. At the same time, the American public attempted to address the epidemic in terms of both public health and civil rights. The public chose to protect the gay community’s civil rights, so the military had to follow suit. President Bill Clinton created “Don’t Ask, Don’t Tell” as a compromise between the alleged military needs and pubic demands. Paradoxically, this policy actually increased discharges of homosexual personnel, cost the military financially, and bred fear and isolation within homosexual service members. And it was the exposure of these injustices that led to its repeal. / Thesis (BA) — Boston College, 2017. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: Departmental Honors. / Discipline: History.

The thesis portrays various spaces in Mumbai where certain non-normative sexualities interact in relation to the consumption of cultural or material resources with which they build their gender, identity and sexuality. In relation to it, this piece of work interrogates the hijra or the popular transvestite population in Mumbai, and the ways in which they represent their bodies. It explores linkages between these processes, and the modern consumption of beauty practices, feminization of their bodies like the consumption of female hormone tablets, and surgical measures like silicone breast implants. Through these mechanisms, the hijras embody beauty and other facets of bodily modifications in constructing their identity. These embodied practices of beauty by the hijras further charts the new meaning of the hijra body in respect to the local identification of their identity in relation to the global transgender identities. Furthermore, with regards to the body modifications and construction of identities, the research also draws attention to the transsexual identified individuals in Mumbai and the clinical discourses that are related to transsexual experience in this context. Thus, the thesis as a whole negotiates the various strands of transgender identities in Mumbai and (dis) similarities in which hijras represent their identities to the society, and claim their gender.

Hepatitis C (HCV) infection is associated with high rates of mortality and morbidity. Interferon alpha based treatment for HCV offers a good rate of viral clearance, however the associated neuropsychiatric side effects increase the risk of treatment interruption and disease progression. The HIV/HCV coinfection is of particular interest due to association with higher rates of HCV treatment side effects and earlier treatment discontinuation when compared with HCV mono-infection. Therefore, the aim of the thesis was to further explore the effect of coinfection on mood and cognition and how HCV interferon based treatment influences neuropsychiatric side effects in mono and co-infected samples. Firstly a meta-analysis was performed to explore cognitive impairment and depression in HIV HCV co-infection. The results suggested that there was consistent literature indicating that the coinfected group were more cognitively impaired and more likely to be depressed than the HCV and HIV monoinfected groups. Secondly empirical studies were conducted to analyse the profile of depression during interferon-based treatment, and explore potential risk factors, such as gender and immune profile. Co-infected patients appeared less vulnerable to the emergence of depressive symptoms during HCV treatment than HCV mono-infected patients. Additionally, neither female gender nor immune response were associated with increased vulnerability to depression. Finally, a longitudinal study investigating cognitive performance during interferon-based treatment was conducted. A significant effect of treatment on information processing speed level of executive function was observed. Overall the research reported in this thesis further clarifies the nature of interferon induced depression and cognitive effects differences between mono and coinfected groups. Having identified a neurovegetative symptom profile and speed of processing impairment of executive function during HCV treatment, the discussion considers the potential of targeted interventions via psychotropic medication and cognitive interventions to minimise the impact of these treatment effects and optimise outcomes in this clinical group.

Research has identified a strong correlation between HIV/AIDS and gender-based violence, yet few studies centre the experiential knowledge of HIV sero-positive women and practitioners. This thesis, based on fieldwork conducted in the Gambia, is grounded in data on HIV positive women's experiences of violence and practices of resistance, revealing context specific complexities and challenges. Data collection methods included diaries, focus groups and in-depth individual interviews with a participant group of sixty sero-positive women in six Gambian HIV Support Societies, and twenty field practitioners working in the areas of violence and HIV/AIDS. I argue in this thesis that there are intersecting underlying factors (patriarchy, gerontocracy and structural violence) that contribute to women's experiences of violence and abuse that render them vulnerable to HIV. In addition, that alongside the more visible gendered violences which intersect with HIV/AIDS. Accounts of women living with HIV revealed that stigma is discreditable and discredited attributes. It contends that stigma should be seen as an ‘everyday' practice of normalised violence, which has very harmful emotional, psychological, economic and physical effects. The research also suggests that violence against women in the context of HIV is not limited solely to male perpetrators. In the Gambia there has been limited success in the translation of women's rights agendas into concrete and effective interventions, partly due to a lack of attention to socio-cultural context and the lived experiences of HIV positive women. The thesis concludes that culturally specific, integrated health and social justice approaches are necessary, which are grounded in women's everyday practices of agency and resistance, and which in particular address the fear of dethronement (loss of power, privileges and prestige) amongst men and older members of society.

This thesis seeks to contribute to knowledge on how sameness and difference play out in personal and professional South-South relations, through an ethnography of interactions between Brazilian and Mozambican development workers, in the HIV&AIDS and gender fields, in Mozambique. The thesis is structured around nine chapters. The introduction outlines the research context, the conceptual frameworks, the key terminology used in the thesis, as well as how my personal and professional life-story inspired this research. In Chapter Two, I discuss the research methodology, sites and spaces, describe the process of multi-sited ethnography in Brazil and Mozambique and reflect about my positionality. The main body of the thesis moves from the macro to the micro level. Chapters 3 and 4 map the reproduction of development and knowledge hierarchies within South-South cooperation institutional discourses and practices and the production of a political economy of opportunities and international mobility for Brazilian development workers. The following chapters discuss how difference and sameness, proximity and distance, and horizontality and verticality are experienced in interactions between Brazilian and Mozambican development workers. Chapter 5 explores principal ways in which the notion of kinship structure relations and imaginaries. Chapter 6 examines affinities, hierarchy and power in an International Non-Governmental Organisation office in Maputo, while Chapter 7 discusses political affinities in feminist knowledge practices. I then analyse the interconnections between the personal, professional and political (Chapter 8) through examining the potential for professional relationships to evolve into something more personal. Chapter 9 concludes the thesis with a review of my findings in the light of the main research question and outlines this thesis' contribution to academic debates on feminist organising, aid ethnographies and South-South relations.

This study sought to evaluate the effectiveness of the GWAPA Single Mothers Poverty alleviation Programme. The study hypothesized that women in Gweru are among the most vulnerable to poverty and disease and GWAPA project may be an effective source to their poverty alleviation. Main objectives of the study were to explain selected development concepts, to explore the relationship between gender and poverty, to investigate the effectiveness of the GWAPA Programme, to outline the challenges faced by GWAPA, and to offer recommendations based on research findings to help improve the effectiveness of the programme. Both theoretical study and empirical research methods were used to ensure a balanced evaluation of the problem. The theoretical study established that the target population for poverty alleviation and development programmes must be fully involved for development to replace poverty. On average women were found to be poorer than men and hence the need for projects that focus on poverty alleviation among women. In the empirical study 375 of the 1756 GWAPA single women members were used as questionnaire respondents, and 3 management employees were sampled for the interviews. Descriptive survey and qualitative participatory approaches were used as the main research methodologies. This hybrid approach was intended to improve the validity and reliability of the outcome of the study by mitigating weaknesses of different individual approaches. This approach would ensure maximum utilization and involvement of subjects and available resources. Questionnaires, interviews and documentary evidence augmented by the researcher's experience with the NGDO were used as research instruments. Of the 375 Questionnaires distributed, 357 (95%) were collected. Various statistical measures were used to summarize and interpret the data, particularly tables, graphs and charts, actual frequencies and percentage rates. Narrative descriptions were also used to explain given scenarios and relationships. The study established that poverty and development are multidimensional concepts, families headed by women are on average poorer than those headed by men, respondents' lives have changed for the better, GWAPA single mothers have work overload especially considering that as women they shoulder the biggest chunk of the family responsibilities, and most of the GWAPA projects which started well were now suffocating under the current economic hardships.. Main challenges faced by GWAPA include the current political and economic environment, the HIV/AIDS pandemic, the limited educational levels among its members, members' limited access to resources, community cultural biases and negative attitudes towards single mothers and commercial sex workers, government regulation on financial transactions and the amount of cash one should hold outside the banking system, and work overload among members. The study recommends involvement of GWAPA members' opposite sex partners as affiliates, intensive public campaigns, lobbying and advocacy to remove the stigma and negative attitudes towards single mothers and commercial sex workers, improving infrastructure and the GWAPA Farm operations, engaging long term facilitators, certification after attending training programmes, excelling awards, present manuals in mother languages, and alternative fundraising strategies. The government and municipalities are encouraged to invest more in the small enterprise sector as it has proven to have the capability to create employment and develop communities by mobilizing the grassroots. The study also recommends a more detailed and deeper participatory study, related comparative studies that show differences and similarities between related projects in different areas in Zimbabwe, and similar studies on DNGOs that work with both sexes in different areas in Zimbabwe. / Thesis (M. Development and Management)--North-West University, Vaal Triangle Campus, 2009.

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This study sought to evaluate the effectiveness of the GWAPA Single Mothers Poverty alleviation Programme. The study hypothesized that women in Gweru are among the most vulnerable to poverty and disease and GWAPA project may be an effective source to their poverty alleviation. Main objectives of the study were to explain selected development concepts, to explore the relationship between gender and poverty, to investigate the effectiveness of the GWAPA Programme, to outline the challenges faced by GWAPA, and to offer recommendations based on research findings to help improve the effectiveness of the programme. Both theoretical study and empirical research methods were used to ensure a balanced evaluation of the problem. The theoretical study established that the target population for poverty alleviation and development programmes must be fully involved for development to replace poverty. On average women were found to be poorer than men and hence the need for projects that focus on poverty alleviation among women. In the empirical study 375 of the 1756 GWAPA single women members were used as questionnaire respondents, and 3 management employees were sampled for the interviews. Descriptive survey and qualitative participatory approaches were used as the main research methodologies. This hybrid approach was intended to improve the validity and reliability of the outcome of the study by mitigating weaknesses of different individual approaches. This approach would ensure maximum utilization and involvement of subjects and available resources. Questionnaires, interviews and documentary evidence augmented by the researcher's experience with the NGDO were used as research instruments. Of the 375 Questionnaires distributed, 357 (95%) were collected. Various statistical measures were used to summarize and interpret the data, particularly tables, graphs and charts, actual frequencies and percentage rates. Narrative descriptions were also used to explain given scenarios and relationships. The study established that poverty and development are multidimensional concepts, families headed by women are on average poorer than those headed by men, respondents' lives have changed for the better, GWAPA single mothers have work overload especially considering that as women they shoulder the biggest chunk of the family responsibilities, and most of the GWAPA projects which started well were now suffocating under the current economic hardships.. Main challenges faced by GWAPA include the current political and economic environment, the HIV/AIDS pandemic, the limited educational levels among its members, members' limited access to resources, community cultural biases and negative attitudes towards single mothers and commercial sex workers, government regulation on financial transactions and the amount of cash one should hold outside the banking system, and work overload among members. The study recommends involvement of GWAPA members' opposite sex partners as affiliates, intensive public campaigns, lobbying and advocacy to remove the stigma and negative attitudes towards single mothers and commercial sex workers, improving infrastructure and the GWAPA Farm operations, engaging long term facilitators, certification after attending training programmes, excelling awards, present manuals in mother languages, and alternative fundraising strategies. The government and municipalities are encouraged to invest more in the small enterprise sector as it has proven to have the capability to create employment and develop communities by mobilizing the grassroots. The study also recommends a more detailed and deeper participatory study, related comparative studies that show differences and similarities between related projects in different areas in Zimbabwe, and similar studies on DNGOs that work with both sexes in different areas in Zimbabwe. / Thesis (M. Development and Management)--North-West University, Vaal Triangle Campus, 2009.

This study sought to evaluate the effectiveness of the GWAPA Single Mothers Poverty alleviation Programme. The study hypothesized that women in Gweru are among the most vulnerable to poverty and disease and GWAPA project may be an effective source to their poverty alleviation. Main objectives of the study were to explain selected development concepts, to explore the relationship between gender and poverty, to investigate the effectiveness of the GWAPA Programme, to outline the challenges faced by GWAPA, and to offer recommendations based on research findings to help improve the effectiveness of the programme. Both theoretical study and empirical research methods were used to ensure a balanced evaluation of the problem. The theoretical study established that the target population for poverty alleviation and development programmes must be fully involved for development to replace poverty. On average women were found to be poorer than men and hence the need for projects that focus on poverty alleviation among women. In the empirical study 375 of the 1756 GWAPA single women members were used as questionnaire respondents, and 3 management employees were sampled for the interviews. Descriptive survey and qualitative participatory approaches were used as the main research methodologies. This hybrid approach was intended to improve the validity and reliability of the outcome of the study by mitigating weaknesses of different individual approaches. This approach would ensure maximum utilization and involvement of subjects and available resources. Questionnaires, interviews and documentary evidence augmented by the researcher's experience with the NGDO were used as research instruments. Of the 375 Questionnaires distributed, 357 (95%) were collected. Various statistical measures were used to summarize and interpret the data, particularly tables, graphs and charts, actual frequencies and percentage rates. Narrative descriptions were also used to explain given scenarios and relationships. The study established that poverty and development are multidimensional concepts, families headed by women are on average poorer than those headed by men, respondents' lives have changed for the better, GWAPA single mothers have work overload especially considering that as women they shoulder the biggest chunk of the family responsibilities, and most of the GWAPA projects which started well were now suffocating under the current economic hardships.. Main challenges faced by GWAPA include the current political and economic environment, the HIV/AIDS pandemic, the limited educational levels among its members, members' limited access to resources, community cultural biases and negative attitudes towards single mothers and commercial sex workers, government regulation on financial transactions and the amount of cash one should hold outside the banking system, and work overload among members. The study recommends involvement of GWAPA members' opposite sex partners as affiliates, intensive public campaigns, lobbying and advocacy to remove the stigma and negative attitudes towards single mothers and commercial sex workers, improving infrastructure and the GWAPA Farm operations, engaging long term facilitators, certification after attending training programmes, excelling awards, present manuals in mother languages, and alternative fundraising strategies. The government and municipalities are encouraged to invest more in the small enterprise sector as it has proven to have the capability to create employment and develop communities by mobilizing the grassroots. The study also recommends a more detailed and deeper participatory study, related comparative studies that show differences and similarities between related projects in different areas in Zimbabwe, and similar studies on DNGOs that work with both sexes in different areas in Zimbabwe. / Thesis (M. Development and Management)--North-West University, Vaal Triangle Campus, 2009.