Den 1 juli 2018 implementerades den så kallade samtyckeslagen i Sverige, vilket bland annat innebar en revidering i våldtäktsbestämmelsen. Från att vara krav på våld, hot, tvång eller utnyttjande av särskild utsatt situation för straffansvar till dagens rekvisit brist på frivillighet. Debatten kring en samtyckesreglering har pågått under en längre tid i Sverige, där det ej införts tidigare dels på grund av att risken att fokus på målsägande i utredningar och rättegångar skulle bli för stort. Syftet med rapporten är därmed att undersöka hur arbetssättet hos brottsutredarna har förändrats sedan lagändringen, samt vad de upplever för eventuella svårigheter och möjligheter i arbetet. Detta har studerats genom fem semistrukturerade intervjuer med utredare anställda av Polismyndigheten med kravet att de ska ha utrett våldtäktsärenden både innan och efter lagändringen. Genom studiens resultat uppkom fem huvudteman; Bevisning, Rättssäkerhet, Vidareutbildning, Målsägandebiträdets roll och Frozen fright. Kort sammanfattat ansåg informanterna att arbetssättet överlag var oförändrat, dock med andra typer av frågor i förhör med målsägande och misstänkt. De upplevde det nya rekvisitet som tydligt men det gick att antyda att de hade önskat mer utbildning i samband med implementeringen. Ett målsägandebiträde spelar enligt informanterna en stor roll i utredningen och kan vara till stor hjälp i deras arbete. Frozen fright är enligt utredarna ett vanligt förekommande tillstånd bland personer utsatta för våldtäkt och det har undersökts i syfte att det med dagens lagstiftning klassas som en våldtäkt om någon utnyttjar en person som befinner sig i denna utsatta situation. Förhoppningen är att rapportens slutsatser kan användas vid implementering av lagar i Brottsbalken samt bidra med kunskap i det fortsatta brottsutredande arbetet och inom rättsväsendet. / The 1st of July 2018 the consent law was implemented in Sweden, which among other things meant a revision in the Rape Act. From requirements of violence, threat, constraint or exploitation of a particularly vulnerable situation for criminal liability to today's necessary prerequisite lack of free will. The debate on consent regulation has been on for a long time in Sweden, with the main reason for not being introduced earlier is because of the risk that focus on the plaintiff in investigations and trials would be too big. The purpose of this report is hence to investigate how the way of working among the criminal investigators has been altered since the change in the law, and what difficulties and possibilities they experience in their work. This have been studied through five semi-structured interviews with investigators employed by the Swedish police authority with the requirement that they should have been investigating rape cases both before and after the change in the law. Five main themes arose through the study's results; Evidence, Legal certainty, Education, The role of the plaintiff’s counsel and Frozen fright. In short, the investigators considered that their way of working was generally unchanged, but with other types of questions in questioning of the plaintiff and suspect. They perceived the new prerequisite as easy to interpret, however, the implementation could have come with more education. According to the informants, a plaintiff’s counsel plays a major role in the investigation and can be of great help in their work. Frozen fright is according to the investigators a common condition among people exposed to rape, in current jurisdiction, it is classified as rape if someone exploits a person who is in this vulnerable situation, therefore why this is studied. The expectation is that the report’s conclusions can be used in the implementation of laws and contribute with knowledge in the continued criminal investigation and in the judiciary.

Thesis advisor: Abhishek Chatterjee / The emergence of genetic code expansion (GCE) technology, which enables sitespecific incorporation of unnatural amino acids (UAAs) into proteins, has facilitated powerful new ways to probe and engineer protein structure and function. Using engineered orthogonal tRNA/aminoacyl-tRNA synthetase (aaRS) pairs that suppress repurposed nonsense codons, a variety of structurally diverse UAAs have been incorporated into proteins in living cells. This technology offers tremendous potential for deciphering the complex biology of eukaryotes, but its scope in eukaryotic systems remains restricted due to several technical limitations. For example, development of the engineered tRNA/aaRS pairs for eukaryotic GCE traditionally relied on a eukaryotic cell-based directed evolution system, which are significantly less efficient relative to bacteria-based engineering platforms. The work described in this thesis establishes a new paradigm in GCE through the development of a novel class of universal tRNA/aaRS pairs, which can be used for ncAA incorporation in both E. coli and eukaryotes. We achieve this by developing engineered strains of E. coli, where one of its endogenous tRNA/aaRS pair is functionally replaced with an evolutionarily distant counterpart. The liberated pair can then be used for GCE in the resulting altered translational machinery (ATM) strain, as well as any eukaryote. Using this strategy, we have been able to genetically encode new bioconjugation chemistries, post-translational modifications, and facilitate the incorporation of multiple, distinct ncAAs into a single protein. The ATM technology holds enormous promise for significantly expanding the scope of the GCE technology in both bacteria and eukaryotes. / Thesis (PhD) — Boston College, 2019. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Chemistry.

”A finger pointing at the moon is not the moon...” -Buddhist Quote ”...but it can point you in the right direction.” -Charles Tart, American psychologist In this Master’s Thesis I will be presenting the idea of an Inner Gaze as an inherent witnessing system used in artistic practice. I will be mirroring my own practice as a Musician/Artist/Sound-Designer in the teachings of Hypnosis and The Science of Consciousness. Further I will share and analyze the collected data gathered from interviews with artists from different artistic fields, in order to gain a better understanding of how they experience their creative and performing minds. Is there any coherence in how we experience creativity? How common are the sensations of altered states of consciousness among artists? Can other artists relate to the idea of an inner gaze? Is this something we long to further explore and develop and would such a concept be beneficial for the artist and its works?

Estimates of production and related parameters (growth rate, density, standing crop) were made for populations of mountain whitefish in altered and "unaltered" areas of the Glacksmith Fork and Logan River, UtJh from spring 1975 through summer 1976. Capture records of marked whitefish were also analyzed to describe fish movement and check on assumptions implicit in the population estimator. Mean weights and instantaneous growth rates of whitefish were similar at all sites for comparable size/age groups. Among sites, differences in production per sampling interval and annual production were due mainly to differences in standing crop and/or age structure. Estimates of mountain whitefish density varied by site and season and ranged from 0 to 3,467 fish/ha, with the highest densities occurring during the fall and winter (spawning season) and the lowest during the summer when streamflows were low. Estimates of standing crops of whitefish followed a pattern similar to density. In the sites where fish remained during the summer most production occurred during the spring and summer. A bulldozed reach of the Logan River (including an "unstable" section) had the highest annual production of mountain whitefish (51.85 kg/ha/yr)--almost double the annual production for the same reach when the unstable section was not included (31.85 kg/ha/yr). The highest annual production of whitefish in sites in the Blacksmith Fork River (51.23 kg/ha/yr) occurred in a reach that had been recently dredged but still contained a riffle and pool structure. Annual production of whitefish was low in a recently bulldozed reach (5.47 kg/ha/yr) and an old bulldozed reach (10.08 kg/ha/yr) of the Blacksmith Fork River where suitable habitat (pools and glides) was lacking, especially during the summer months. Mountain whitefish remained or returned to reaches after channel alterations as long as water depth remained sufficient. This study illustrated the necessity of frequent sampling when attempting to evaluate the effects of perturbations on fish populations or in production studies in general.

Bakgrund: Bröstcancer är vanligaste typen av cancer bland kvinnor i världen samt orsakar flest dödsfall av cancerformerna. Drabbas av bröstcancer har väsentlig påverkan på unga kvinnors liv, behandling kräver specifik kompetens gällande sexualitet, fertilitet samt graviditet. Antonovsky beskriver att ”KASAM”- känsla av sammanhang, bidrar till ökad förmåga att hantera svårigheter som det kan innebära att få diagnos och hantera sjukdom som bröstcancer. Hög grad av KASAM kan hjälpa kvinnor att hantera och acceptera livssituationen.Syftet är att beskriva unga kvinnors upplevelser av att få bröstcancerdiagnos i samband med diagnostik och behandling. Metod: Litteraturöversikt med induktiv ansats baserad på 12 vetenskapliga kvalitativa artiklar som analyserades enligt Fribergs (2017) fem steg. För artikelsökningen användes databaserna Cinahl och MedLine. Resultat bestod av tre huvudkategorier och åtta underkategorier som sammanställdes.Huvudkategorierna är att få bröstcancerdiagnos (upplevda känslor, återgå till vardagen, acceptans och balans), förändrad kropp (kroppsuppfattning och identitet, sexuell hälsa, fertilitet och graviditet) och trygghet genom stöd (närståendes stöd, sjuksköterskors stöd). Slutsats: Enligt denna litteraturöversikt blev slutsatsen att bröstcancer påverkar den unga kvinnans känsloliv, vardag, kroppsuppfattning, identitet, sexuell hälsa, fertilitet samt graviditet. Närstående och sjuksköterskor kan vara det huvudsakliga stödet och hjälpa kvinnor att bekämpa bröstcancer. / Title: Young women's experiences of being diagnosed with breast cancer. A literature review.   Background: Breast cancer is most common type of cancer among women in the world and causes the most deaths from the cancers. Suffering from breast cancer has a significant impact on the lives of young women. Young women's treatment requires specific skills regarding sexuality, fertility and pregnancy. Antonovsky describes that "SOC" - sense of coherence, contributes to an increased ability to deal with difficulties that it may mean to be diagnosed and manage a disease as breast cancer. Strong SOC can help women manage and accept the life situation. The aim is to describe young women's experiences of being diagnosed with breast cancer associated with diagnosis and treatment. Method: Literature review with inductive approach based on 12 qualitative articles that were analyzed with Friberg's (2017) five steps. Cinahl and MedLine were used for the article search. The result consists of three head categories and eight subcategories. The main categories are getting breast cancer diagnosis (perceived emotions, return to everyday life, acceptance and balance), changed body (body perception and identity, sexual health, fertility and pregnancy) and security through support (relatives 'support, nurses' support). Conclusion: According to this literature review, the conclusion was that breast cancer affects young woman's emotional life, everyday life, body image, identity, sexual health, fertility and pregnancy. Close relative and nurses can be the main support and help women fight breast cancer.

Sound localisation is one of the most representative function of the auditory system and, as such, it has been extensively investigated across species. Spatial hearing can be dramatically altered across the life span, yet research in humans have highlighted the remarkable capacity of the brain to adapt to changes of listening conditions, such as temporary ear plugging or long lasting hearing impairments. Although several investigations have examined accommodation to altered auditory cues (Chapter 1), a common theoretical framework seems to lack and a number of questions remain open. This limits the possibility to translate our current knowledge into concrete clinical applications for individuals who experience spatial hearing difficulties after hearing loss. The current dissertation reflects the attempt to answer specific questions regarding the process of sound localisation. The first study (Chapter 2) aimed to investigate the relation between different reference frames in spatial hearing, namely egocentric and allocentric sound representation. We studies this topic in the context of a learning paradigm, assessing to what extent localisation of single sounds in simulated monaural hearing (unilateral ear plugging) can improve following an audio-visual spatial hearing training focused on egocentric sound processing vs allocentric sound processing. An untrained group was also included in the study. We found that localisation performance in the horizontal plane improved specifically in the side ipsilateral to the ear-plug for all groups. Yet, the trained groups showed a qualitatively different change of performance after four days of multisensory ego/allocentric training compared to the untrained group, providing initial evidence of the possible role of allocentric coding in acoustic space re-learning. These results further highlight the importance of including a test-retest group in paradigms of sound localisation training. The second study (Chapter 3) focused on a specific aspect of the phenomenological experience of spatial hearing, namely the subjective confidence about the perceived sound position. We examined the relation between objective localisation accuracy and subjective certainty while participants localised sounds in two different listening conditions – binaural or simulated monaural hearing. Results showed that overall subjective certainty on sound position decreased in the altered listening condition (unilateral ear-plugging). In simulated monaural hearing, localisation accuracy and spatial confidence dissociated. For instance, there were trials in which participants were accurate, but felt uncertain, and trials in which they were less accurate but expressed higher ratings of spatial confidence on sound position. Furthermore, subjective confidence increased as a function of time within the testing block, and it was related to the spatial distribution of the perceived sound-source position. The third study (Chapter 4) exploited magnetoencephalography (MEG) to study the dynamics of the cortical network implied in active sound localisation. We implemented a novel apparatus to study sound localisation in MEG with real sounds in external space, and collected behavioural and subjective responses (i.e., accuracy and confidence, as in Study 2) during this altered listening condition. Results showed that participants were able to perceive the spatial difference between the positions of stimulation, thus proving the reliability of our novel setting for the study of spatial hearing in MEG. MEG data highlight a distributed bilateral cortical network involved in active sound localisation, which emerged shortly after stimulus presentation (100—125 ms). The network comprise the classical dorsal auditory pathway plus other cortical regions usually underestimated in previous literature – most notably, regions in the central sulcus/precentral gyrus possibly involved in head movements. Connectivity analysis revealed different patterns of neural coupling, as a function of frequency band. In particular, coherence in high gamma revealed significant connections involving the parietal cortex and the posterior superior temporal cortex. In the final chapter (Chapter 5), I summarise the main findings of the three studies, discuss their implications and outline potential future directions.

No description available.

Christian Spirituality, Church History and Missiology / D. Th (Christian Spirituality, Church History and Missiology)

AIM: The aim of this investigation is to determine the prevalence of maxillary altered passive eruption in a dental school population. METHODS: 100 subjects were examined clinically and had models fabricated of their maxilla. Demographic, periodontal, cast measurements were recorded for each subject. Demographic variables recorded included age, gender, and ethnicity, history of orthodontic treatment, presence of incisal /occlusal wear, appearance of gingival excess, and presence of gingival asymmetry. Measurements made on cast included clinical crown length, clinical crown width, papillary height, and distance from the lateral gingival zenith to the gingival aesthetic line. Clinical crown width-to-length ratio was calculated. These measurements were compared to previously published standards. RESULTS: 83% of the subjects had central incisors with a clinical W:L ratio greater than .80. Logistical regression analysis determined that subjects with central incisors with an appearance of gingival excess were more likely to have a clinical W:L ratio greater than .80 (P<.0007; OR=79). ANOVA demonstrated that clinical crown length had a statistically significant relationship with gender (P<.0001), tooth type (P<.0001) and biotype (P<0.0026). Clinical crown width and clinical crown W:L ratio had a statistically significant relationship with gender (P<0.0007, P<.0001) and tooth type (P<0.0026, P<.0001). The average clinical crown length was 0.5-1.5 mm shorter than established ideal measurements. CONCLUSION: 83% of the subject population had central incisors that displayed altered passive eruption. Subjects who exceeded the clinical W:L ratio of .80 were more likely to have been classified as having the appearance of gingival excess or “gummy smile”. Esthetic crown lengthening should be considered to achieve desired esthetics in these subjects.

Background: Psychonautics is a scientific method used to describe intoxication and effects of psychoactive substances and a form of recognition used by some in order to achieve self- experience and transcendence. Hallucinogenic and psychedelic substances most commonly used for this purpose can possess therapeutical, but also destructive potential, how many researches on the psychedelic therapy topic have shown. During auto-experiments, these substances are being used in nonclinical environment and often without professional or other control, which can lead to many risks, but also benefits. Aim: The goal is to understand the way of psychonautics self-defining through statements and actions of psychonauts. The main goal is to describe a pattern of drug use, subjective consequences and meaning of psychoactive substances use in the lives of the psychonauts from their point of view. Sample: Research set consisted of 5 respondents chosen based on two methods - the snowball method and intended selection. Methods: The used method of data collection was a semistructured interview, in which the collected data was analysed by the clustering method and pattern recording method and an online questionnaire that has been evaluated based on descriptive analysis principles by an answer sheet. Results:...