The primary goal of this work is to validate the visual analog screening scale Emotion Thermometer (ET) in patients with chronic non-cancer lower back pain. In addition, the work aimed to verify the presumed relationships of clinically significant anxiety, its related concepts and depression with chronic pain and to explore which factors predict decrease in level of function and presence of psychiatric diagnosis according to MINI in patients with chronic pain. In the first chapter, the theoretical part of the thesis deals with the description of the ET tool and a systematic overview of validation and empirical studies. The second chapter focuses on mapping the relationships between stable affective components of ET (distress, anxiety, depression, anger) and chronic pain. The empirical part of the work has a quantitative design and is realized in the form of observational analytical cross-sectional study, in which two hundred and eighty-one patients hospitalized at the Department of Rehabilitation and Sports Medicine of the 2nd Faculty of Medicine at Charles University and at the University Hospital in Motol participated. Participants of the study underwent a clinical examination in the form of an interview and a questionnaire survey. 16 % of the participants met the MINI criteria for major...

Introduction: The current study examined the psychosocial predictors (Type D personality, anxiety, depression & social support) in patients following MI. It further assessed the influence of these psychosocial predictors on quality of life of MI patients. Methods: In this prospective cohort study, 300 patients with definite myocardial infarction were recruited and assessed at baseline (2 -8 weeks) post MI (time 1). Out of 300 participants 191 completed assessments at 9 months follow up (time 2). Type D personality was evaluated with Distress scale 14(DS-14). Depression and anxiety were assessed with Hospital anxiety and depression scale (HADS). Social support was measured with Social support scale (SSS), while quality of Life was assessed with WHO quality of life scale (WHOQOL-BREF) at time 1 and time 2. Results: Analysis revealed that a significantly high percentage of MI patients had Type D personality characteristics, high levels of anxiety, depression and low level of social support. Type D personality and depression emerged as most significant predictors of quality of life after controlling for sociodemographic and clinical variables at time 1 and time 2 assessments. Discussion & Conclusion: This research emphasized the importance of Type D personality, anxiety, depression, and lack of social support in risk stratification for adverse outcomes such as impaired quality of life. This research highlighted the need for a more personalized approach to therapeutic interventions along with medical treatment for the management and rehabilitation of MI patients. / Fatima Jinnah Women University of Pakistan and The Higher Education Commission

Pain catastrophizing (PC) and fear of pain (FOP) are understudied across different race/ethnicity minorities. The association between these constructs and psychological disorders with relation to chronic pain are understudied as well. Prior research indicates that racial/ethnic minority populations may engage in more PC and FOP than white, non-Hispanic populations. These studies, however, have only examined macro-level differences between white, non-Hispanic and minority populations. Less is known about the nuanced differences in PC and FOP across individual racial/ethnic groups (i.e., white vs. Asian vs. Black/African American). The current study explores between-group differences in PC and FOP across diverse racial/ethnic groups of youth with chronic pain while also observing the association between anxiety/depression and PC/FOP in these populations. Youth (ages 11-17) with chronic pain presenting for treatment to a tertiary pediatric pain clinic completed the Pain Catastrophizing Scale (PCS), which includes a total score and subscales (i.e., rumination, magnification, and helplessness) and the Fear of Pain Questionnaire. Racial/ethnic group sizes were as follows: Black/non-Hispanic (N = 29), Hispanic (N = 58), Asian (N = 17), another race/non-Hispanic (N = 37), and Multiracial (N = 15). One-way ANOVAs were conducted to test differences in the PCS total score and subscales as well as FOP among racial/ethnic groups, and Chi-square analyses were conducted to test the association between binary codes of anxiety/depression diagnoses provided in the data repository and the race/ethnicity minorities, respectively. Results revealed non-significant differences in total PCS and PCS subscales across race/ethnicity minority groups. In addition, there were no statistically significant differences in FOP across race/ethnicity minority groups. However, there were some clinically significant differences between mean PCS and FOP scores across certain racial/ethnic minority groups. Finally, no significant associations emerged between anxiety and race/ethnicities or between depression and race/ethnicities. Findings suggest that youth with chronic pain may experience PC and FOP similarly regardless of their racial/ethnic backgrounds. However, these findings were limited by small sample sizes across groups, and future research with larger sample sizes is warranted. These results can inform continued exploration and sensitivity to diversity, equity, and inclusivity issues in healthcare for pediatric chronic pain patients.

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Derived from the ancient mind-body practice and congruent with western scientific studies, the 8-Week Program to Support Undergraduate Academic Aptitude draws specific modalities from the 5,000-year-old Yoga tradition for helping lower undergraduate anxiety, depression, and stress. The program emphasizes use of physical postures, breathing exercises, basic mediation, and philosophy. Selectively chosen, the clinically researched techniques create physiological shifts for offsetting anxiety and depression in undergraduates, two factors known for adversely affecting students’ health and academic readiness. The main goal of the program is to educate a student to use Yogic tools intelligently and effectively for emotional, mental, and physical health to support quality of life and flourishing academically. A student’s health, wellness, and happiness are key contributing factors to staying engaged with an institution and student attainment.

Paradoxen är tydlig: äldre är mest oroliga över att utsättas för brott trots att de löper minst risk att faktiskt utsättas för brott. Denna oro är speciellt hög hos äldre kvinnor. Denna studie ämnar att undersöka om ångestbenägenhet och sociala nätverk har en påverkan på oro för brott. Frågeställningen lyder enligt följande: Vilken påverkan har ångestbenägenhet och sociala nätverk på oron att utsättas för brott hos kvinnor äldre kvinnor? Studiens resultat fann ett positivt samband mellan oro övergående i ångest och oro för brott. Sociala nätverk hade även en positiv effekt på oro för brott. Slutsatsen av denna studie är att det finns ett samband mellan oro för brott och ångestbenägenhet men att den sistnämnda existerar i högre grad. Ytterligare studier måste tillämpas kring sambandet mellan sociala nätverk och oro för brott. / The paradox is clear: elderly have the highest fear of crime even though they have the lowest risk to actually get exposed to crime. Especially women report high fear of crime. This study aims to explore the affect of trait anxiety and social relationships on fear of crime. The problem statement is: what affect has trait anxiety and social networks on fear of crime among older women? The result of this study found a positive association between anxiety and fear of crime. Social network had also an positive affect on fear of crime. The conclusion of this study is that there is a association between fear of crime and anxiety but that anxiety is more frequent. More studies on the association between social network and fear of crime needs to be made.

Unfavorable interpersonal behavior in social anxiety disorder (SAD) contributes to the maintenance of the disorder and may also be related to the development of secondary depression. Since there is limited research on daily life behavior in SAD, this study aimed to describe social interaction behavior and analyze the effect of positive interactions on depression, anxiety, and mental state. Data were obtained from the Behavior and Mind Health study (11/2015–12/2016), an epidemiological cohort study of adolescents and young adults (n = 1,180, aged 14–21 years) from Dresden, Germany. Interpersonal behavior, current mental state, anxiety, and depression were assessed eight times per day over four days using smartphone-based ecological momentary assessments. The analyzed subsample consisted of n = 723 participants, comparing 12-month SAD (n = 60) and healthy controls (HC; n = 663). The interaction behavior of participants with SAD did not differ substantially from that of HC in terms of frequency of social interactions, type of interaction partner, and time spent communicating, although they reported fewer real-life interaction partners (SAD: M = 2.49, SD = 4.78; HC: M = 3.18, SD = 6.43; F(17,044) = 23.92, p < 0.001). When comparing mental state, anxiety, and depression after interactions with familiar people to no interaction, no differences were found between SAD and HC. However, interactions with unfamiliar people negatively affected depressive symptoms in individuals with SAD (b = 0.53; SE = 0.25; 95%CI: 0.04–1.03; p = 0.036). In adolescents with SAD, social situations with unfamiliar people seem to be processed in a dysfunctional way, contributing to increased depressive mood in everyday life. This is particularly interesting given the high rate of secondary depression in SAD.

The present meta-analytic study examined the overall effectiveness of child-centered play therapy (CCPT) and child-parent relationship therapy (CPRT) for children experiencing internalizing problems. After conducting a comprehensive literature search and review, 25 studies published between 2000 and 2023 met the following inclusion criteria: (a) published and peer-reviewed; (b) used CCPT or CPRT as an intervention; (c) participants were ages 3 to 13 or parents of children ages 3 to 13; (d) study outcomes related to children's internalizing problems, such as anxiety, depression, or withdrawal; (e) used single group within study or between study design, including randomized controlled trials and non-randomized controlled trials; (f) published between January 2000 and April 2023; (g) published in English; (h) used standardized measurements; and (i) reported effect sizes, or means and standard deviations, or the author disclosed the means and standard deviations upon request. Final analysis included 28 individual effect sizes using a random effects model to determine the overall effect size for 6 analyses that included CCPT/CPRT combined between, CCPT/CPRT combined within, CCPT between, CCPT within, CPRT between, CPRT within. Moderating variables included gender, age, ethnicity, and number of CCPT sessions. CCPT and CPRT effect sizes were statistically significant and ranged from small to large effects. Results support the use of CCPT and CPRT with children for the reduction of internalizing problems. Procedures and results, including the coding process, limitations, and implications are discussed.

Prolyl oligopeptidase (PREP) has been implicated in neurodegeneration and neuroinflammation and has been considered a drug target to enhance memory in dementia. However, the true physiological role of PREP is not yet understood. In this paper, we report the phenotyping of a mouse line where the PREP gene has been knocked out. This work indicates that the lack of PREP in mice causes reduced anxiety but also hyperactivity. The cortical volumes of PREP knockout mice were smaller than those of wild type littermates. Additionally, we found increased expression of diazepam binding inhibitor protein in the cortex and of the somatostatin receptor-2 in the hippocampus of PREP knockout mice. Furthermore, immunohistochemistry and tail suspension test revealed lack of response of PREP knockout mice to lipopolysaccharide insult. Further analysis revealed significantly increased levels of polysialylated-neural cell adhesion molecule in PREP deficient mice. These findings might be explained as possible alteration in brain plasticity caused by PREP deficiency, which in turn affect behaviour and brain development.