Bisfenol A (BFA) é usado em uma variedade de produtos de consumo, incluindo alguns tipos de papéis, principalmente os papéis termossensíveis, no qual é utilizado como revelador. Mesmo assim, pouco é conhecido sobre a magnitude da contaminação ou exposição humana ao BFA, como resultado do contato com papéis. Neste estudo, foi desenvolvido e validado uma metodologia para determinação de BFA por espectroscopia de fluorescência sincronizada. O método desenvolvido e validado é rápido, simples e de baixo custo e apresenta boa sensibilidade, sendo apropriado para aplicação em amostras de papéis. O método apresentou linearidade no intervalo de concentração entre 25 e 450 ?g.L-1 (r = 0,9993). Os limites de detecção e quantificação foram de 1,20 e 3,99 ?g.L-1, respectivamente. Valores de precisão inter e intra ensaio foram de 3,21 a 8,54% e de 0,29 a 3,92%, respectivamente. A exatidão variou de 87,4 a 111% (para as concentrações de 25, 250 e 450 ?g.L-1). Os valores de recuperação estiveram entre 100 e 102% (amostra extraída). A metodologia validada foi aplicada na determinação de BFA em 13 tipos de produtos de papel (n=444), incluindo papel termossensível (n=341), bilhete de loteria (n=7), bilhete de ônibus (n=5), cartão de visita (n=12), envelope (n=11), flyer (n=10), guardanapo (n=8), papel de impressão sulfite A4 (n=3), embalagem de alimento (n=20), papel higiênico (n=8), papel toalha (n=4) e revista (n=9), jornal (n=6). BFA foi encontrado em 98% das amostras de papel termossensível (n =341) com concentrações variando desde menores que o LQ até 27,7 mg.g-1 e média geométrica e mediana de 14,6 mg.g-1 e 17,7 mg.g-1, respectivamente. Já a maioria (96%) dos outros tipos de papéis analisados (n = 103) apresentou concentrações de BFA variando desde menores que oLQ até 379 ?g.g-1 e média geométrica e mediana de 14,7 ?g.g-1 e 17,3 ?g.g-1,respectivamente. Os papéis termossensíveis apresentaram mais altas concentraçõesde BFA (ordem de mg.g-1) comparado aos outros tipos de papéis analisados,principalmente os produzidos a partir de papel reciclado com concentrações na ordemde ?g.g-1. A estimativa da exposição humana ao BFA através da manipulação de ii diferentes tipos de papéis foi estimada baseado na concentração de BFA e frequência de manipulação. A ingestão diária aceitável de BFA, ajustada pelo peso corporal (calculado para a mediana das concentrações), através da absorção dérmica, via manipulação de papéis pela população em geral e por indivíduos expostos ocupacionalmente foi de 14,5 e 1070 (ng/Kg peso corporal/dia), respectivamente / Bisphenol A (BPA) is used in a variety of consumer products, including some paper products, particularly thermal receipt papers, for which it is used as a color developer. Nevertheless, little is known about the magnitude of BPA contamination or human exposure to BPA as a result of contact with papers. In this study, was develop and validate an methodology for determination of BPA by synchronous fluorescence spectroscopy. The developed and validated method was fast, easy, low cost, with a good sensibility and appropriate for application in paper samples. The method was linear on the range of to 25 a 450 ?g.L-1(r = 0,9993). The detection and quantification limits were 1,20 and 3,99 ?g.L-1 respectively. Inter and intraday precision were between 3,21 to 8,54% and 0,29 to 3,92%, respectively. Accuracy was between 87,4 to 111%. The recovery was between 100 to 102 % (extracted samples). The validated methodology was applied in the BPA determination in 13 types pf paper products (n=444), including thermal receipt papers (n=341), lottery tickets (n=7), bus tickets (n=5), business cards (n=12), mailing envelopes (n=11), flyers (n=10), napkins (n=8), printing paper (n=3), food contact paper (n=20), kitchen rolls (n=4), toilet paper (n=8), newspaper (n=6), and magazines (n=9). BPA was found in 98% of thermal receipt papers (n = 341) at concentrations ranging from below the limit of quantitation (LOQ) to 27,7 mg.g-1 with a geometric mean of 14,6 mg.g-1 and a median of 17,7 mg.g-1. The majority (96%) of other paper products (n = 103) contained BPA at concentrations ranging from below the LOQ to 379 ?g.g-1 with a geometric mean of 14,7 ?g.g-1 and a median of 17,3 ?g.g-1. Whereas thermal receipt papers contained the highest concentrations of BPA (milligram-per-gram), the others types of papers, especially those produced from recycled paper contain lower concentrations of BPA (microgram-per-gram). Estimation of human exposure to BFA through manipulation of different paper types was calculated based on the measure of concentration and frequency of manipulation. The estimated daily intake for BFA adjusted body weight (calculated at median concentrations) through dermal absorption from handling of papers was 14.5 and 1070 ng/day for the general population and occupationally exposed individuals, respectively.

Vi vet att fysisk aktivitet är någonting som är bra för våran hälsa både fysiskt och psykiskt. Detta är någonting som många studier bekräftar. Detta arbete handlar om att hitta ett koncept som hjälper läraren att ha fysisk aktivitet i det teoretiska klassrummet när det är lektion eller när klassen behöver ta en liten paus från lektionen. Konceptet är baserat på Motion Control Gaming och är en vision på hur ett det skulle funka, både som system, interface och produkt.

For my thesis project, I displayed fifteen printed photographs of self-portraits that I have made outside of class. In these self-portraits, I have applied special effects makeup to my face to create different portrayals of myself. These range from more abstracted makeup to characters. The majority of these makeups are from the chest up and created with face paint and self-made prosthetics. In this imagery, I have also chosen accessories and the background to coincide with the makeup and the mood that I am conveying. Minor adjustments have been made digitally in order to enhance how the image comes across. For example, I have upped the contrast and dimmed the exposure, etc. I have taken most of my own photographs on my phone or Canon Rebel Xi camera while there are a few that a family member has taken for me. I printed these portraits at a larger than life scale and I chose to display them at a place that has become close to home, O’mainnin’s Pub and Grill. This pub is where I held my show. My art was displayed in the casual environment with loud music and dim colorful lights. The exhibit stayed up for three days and was available to the public. Alongside my photographs, I also chose a handful of traditional hand-drawn classwork to display as well. This work is very similar in theme and compliments the self-portraits. Below are images of the show!

PiteEnergi har under några års tid planerat för att öka redundansen i sitt 40 kV-nät och därmed förbättra driftsäkerheten och möjligheten att välja alternativa matningsvägar vid behov. Detta examensarbete innefattar en förstudie med beräkningar av bland annat spänningsfall och kortslutningsströmmar med kabel- och luftledningsalternativ, vid olika matningsvägar, för en ny delsträckning. Den ska fungera som ett underlag för den fortsatta processen att bygga den nya ledningen. Den nya sträckningen förväntas fungera som en reservledare, det vill säga den kommer att vara normalt öppen och därmed inte användas i den dagliga driften. För att undersöka möjliga alternativ gjordes en belastningsfördelningsanalys (BFA) och spänningsstabilitetsanalys i det Matlab-baserade programmet MATPOWER. Det befintliga nätets data samt den tilltänkta nya sträckningen analyserades utifrån olika aspekter, såsom olika matningsvägar, luftledning- och kabelalternativ och en eventuell framtida ökad belastning. Det framkommer i arbetet att det finns flera möjliga lösningar, som håller sig inom givna gränser och som även ger utrymme för en större last än den som finns idag, utan att för den sakens skull äventyra driftsäkerheten i systemet.  För det framtida ledningsvalet ges därför i diskussionsdelen en del synpunkter att ta hänsyn till när projektet väl sätter i gång. Dessa bör sättas i förhållande till andra aspekter som ligger utanför detta arbete, såsom exempelvis ekonomiska förutsättningar, tillståndsansökningar och markåtkomstfrågor.

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Protein trafficking between the endoplasmic reticulum (ER) and Golgi complex is regulated by the activity of ADP-ribosylation factors (Arfs). Arf activation by guanine nucleotide exchange factors (GEFs) leads to the recruitment of the coatomer protein COPI and vesicle formation. By using fluorescently-tagged proteins in live cells, we have been able to identify novel functions for Arfs and the Arf-GEF GBF1 at the ER-Golgi intermediate compartment (ERGIC) and mitotic Golgi clusters. We first focused on Arf function at the ERGIC after observing both class I (Arf1) and class II (Arfs 4 and 5) Arfs at this structure. We discovered that class II Arfs remain bound to ERGIC membranes independently of GBF1 activity following treatment with brefeldin A (BFA). Further characterization of the class II Arfs using additional pharmacological agents such as Exo1 and inactive mutant forms of Arf4 demonstrated that the class II Arfs associate with the ERGIC membrane via receptors distinct from GBF1. Our work suggests that GBF1 accumulation on membranes in the presence of BFA is due to loss of Arfs from the membrane rather than the formation of an abortive complex with Arf and GBF1. Next, while studying GBF1 in live cells, we unexpectedly observed GBF1 localizing to large fragmented structures during mitosis. We identified these structures as mitotic Golgi fragments that are positive for GBF1 and COPI throughout mitosis. Again using live cells treated with BFA and Exo1, we demonstrated that GBF1 concentrates on these mitotic fragments suggesting that they are derived from Golgi membranes. By colocalization studies and fluorescence recovery after photobleaching, we demonstrated that these mitotic fragments maintain a cis-to-trans subcompartmental Golgi polarization and membrane dynamics of GBF1 similar to interphase cells. Interestingly, inactivation of GBF1 and loss of COPI from the membranes of the mitotic Golgi fragments did not delay progressing through mitosis. Our results from our second project indicate for the first time that the mitotic Golgi clusters are bona fide Golgi structures that exist throughout mitosis with a functional COPI machinery.

70% of the fresh water and 40% of the earth surface is used for agriculture purposes. Today we throw away nearly every 3rd grocery bag we buy. By doing this we waste a lot of the worlds resources. Only in Sweden we spoil 1.2 billion tons of food every year. 700 000 tons of this is from the households. The biggest source to the waste is single households and families with children, this became the target group for this project. We have to change our behavior to preserve the earth’s resources. The research showed that the biggest reasons that we throw so much food is that we first of all buy too much food. We don’t have time to eat all the food we buy and it get therefore spoiled. This is a consequence from that we don’t see it as a problem. There is a lack of knowledge in how much we throw away and how to store food correctly. We are bad at planning our meals and grocery shopping and we end up with too much food because of this. This project investigates how we can reduce the food waste. The analyzed problem areas was used as a starting point in the ideation. The project focus is during the storing of the food in the households and how to keep track on the food we have. The storing of the food can be divided in three parts, make food last longer, plan the meals and shopping and keep track on the food we have. The final result is the smart food storage. It is a concept that helps the user to get a good overview of the food and to store it in the optimized way. It enables for planning of grocery shopping and helps you keep track on the food you have.

Forests cover about 30% of the earth surface and is a vital resource as a habitat for plants, animals and humans. Today climate change and global warming is a fact and something must be done. We burn massive amounts of fossil fuels and during this combustion carbon dioxide is created. To help eliminate this global change we need to start caring about the forests. The forests have a major role in climate change and global warming. It currently contributes to about one-sixth of the global carbon emissions. But today deforestation is a real environmental threat. The world trees are being cut down too quickly for the earth to regenerate new forests. And while the society is moving into a more bio-based economy the pressure of a efficient forest industry and forest regrowth is increasing drastically. A new way of reforestation must happen, a sustainable and natural method must be im plemented. In Sweden and the Scandinavian area the method has had a stagnant development. Is done manually with a standardized procedure not taking natural properties into account. Money often goes over quality. My project will focus on developing a concept that can live up to the upcoming future demands and the environmental aspects that needs to be taken in account to ensure a healthy and sustainable forest. The final result performs an efficient and precise reforestation and enables for a detailed planning and analysis of the area in advanced.

30% of children and youths in Sweden have some form of allergy disease and for many people medicines are not sufficient. If so, there is a possibility of an allergy vaccination, a three to five-year process where the patients receive 50-80 injections. So what is the main problem? In fact, it is important to understand that the vaccination is something that affects the child in greater extent than just the moment when the syringe is provided. At present, the patient must stay to ensure that he/she does not get an allergic reaction and is feeling well enough to go home. They are constantly questioned about how they feel. But how does a child determine this? How good is good enough? Topi is a system that increases the involvement and transfer responsibilities from the child by keeping track of their well-being and surroundings - while making treatments more fun and safe. The project is funded by Swedish Asthma and Allergy Association´s Research Foundation

This item contains the agenda, minutes, and attachments for the Faculty Senate meeting on this date. There may be additional materials from the meeting available at the Faculty Center.