Global ETD Search

31	Research Participation Decision-Making Among Youth and Parents of Youth with Chronic Health Conditions: A Dissertation Pagano-Therrien, Jesica 11 April 2016 (has links) The purpose and aims of this qualitative descriptive study were to describe how past experiences with research (including communication, information, values and support) may contribute to research fatigue among youth and parents of youth with HIV, CF, and T1D. Eighteen parents and youth were purposively recruited from outpatient subspecialty clinics at a major academic medical center. They took part in qualitative interviews, completed a demographics form, and the Decisional Conflict Scale. Youth participants also completed the Erikson Psychosocial Stage Inventory. Two major themes emerged: blurred lines and hope for the future. Research fatigue was not found in this sample. Results point to challenges with informed consent in settings where research and clinical care are integrated, and suggest that protective factors allow for continued participation without excess burden on youth and parents. Strategies to minimize research fatigue and support engagement in research are offered. Chronic health conditions decision-making informed consent pediatrics research participation Adolescent Chronic Disease Outpatients Parents Qualitative Research Parental Consent Patient Participation Bioethics and Medical Ethics Health Services Administration Health Services Research Pediatric Nursing Pediatrics
32	A Proposal to Test the Effects of Factor ECAT1 on Pluripotency, from Reprogramming to Differentiation of Human Somatic Cells Goel, Vritti R. 01 January 2012 (has links) The field of stem cell research has been growing more because of the interest in using stem cells to cure diseases and heal injuries. Human embryonic stem cells, because of the controversy surrounding them—and subsequently the difficulties in acquiring samples of the existing aging cell lines—can only be used in limited capacities. While the development of induced pluripotent stem cells in the last decade has allowed the field to progress closer to medical treatments, the low efficiency of reprogramming a somatic cell to a pluripotent state, and the vast molecular and genomic differences between human embryonic stem cells and human induced pluripotent stem cells is still an issue. Therefore, the goal is to discover methods, chemicals, and factors that can reduce these differences and increase the efficiency of inducing pluripotency. This proposal aims to look at the effects of the protein ECAT1 in inducing pluripotency in human somatic cells. Little is known about ECAT1, otherwise known as Embryonic Stem Cell-Associated Transcript 1, beyond its presence in human embryonic stem cells and oocytes and its absence in differentiated cells. While originally considered by scientists during the development of the reprogramming technique, ECAT1's effects have not been tested in humans. Therefore, a series of experiments will be performed in which ECAT1 will be used in conjunction with OSKM to induce pluripotency in adult human dermal fibroblasts, which will then be differentiated into spinal motor neurons. The three stages of this proposal--inducing pluripotency, comparing pluripotencies in the reprogrammed cells and embryonic stem cells, and differentiating the stem cells--should answer questions about ECAT1 and the reprogramming process. It is predicted that ECAT1 should reduce the genomic and molecular differences between embryonic stem cells and induced pluripotent stem cells. ECAT1's presence should also increase the efficiency of reprogramming as well as successful differentiation to other cell types. stem cells OSKM induced pluripotency reprogramming differentiation ECAT1 Amino Acids, Peptides, and Proteins Bioethics and Medical Ethics Bioinformatics Biological Factors Biology Cell Biology Cellular and Molecular Physiology Developmental Biology Enzymes and Coenzymes Genetic Structures Medical Molecular Biology Molecular and Cellular Neuroscience Molecular Biology
33	Stasi Brainwashing in the GDR 1957 - 1990 Solbrig, Jacob H., Solbrig, Jacob Hagen 20 December 2017 (has links) This thesis examines the methods used by the Ministerium für Staatssicherheit (MfS), more commonly known as the Stasi, or East German secret police, for extraction of information from citizens of the German Democratic Republic for the purpose of espionage and covert operations inside East Germany, as it pertains to the deliberate brainwashing of East German citizens. As one of the most efficient intelligence agencies to ever exist, the Stasi’s main purpose was to monitor the population, gather intelligence, and collect or turn informants. They used brainwashing techniques to control the people of the GDR, keeping the populace paralyzed with fear and paranoia. By surrounding themselves with a network of informants they prevented actions against the dictatorial communist regime. Using the video testimonies of former prisoners, and former confidential informants who worked closely with and collaborated with Stasi agents, in combination with periodicals and previous historical studies, this work argues that the East German Police State’s brainwashing techniques had long and lasting consequences both for German citizens, and for the psychiatric health of former GDR citizens. The scope and breadth of the techniques and data compiled for use by the Stasi were exhaustive, and the repercussions of their use are still being felt and discovered twenty five years after the fall of the Berlin Wall. This study aims to show the lasting effects brainwashing had on former informants and the Stasi’s victims. Stasi brainwashing cold war spy kgb psychological Applied Ethics Behavior and Behavior Mechanisms Bioethics and Medical Ethics Continental Philosophy Cultural History Eastern European Studies Ethics and Political Philosophy European History European Languages and Societies Experimental Analysis of Behavior Intellectual History Modern Literature Multicultural Psychology Oral History Other German Language and Literature Other Languages, Societies, and Cultures Other Political Science Philosophy of Mind Political History Politics and Social Change Psychiatry Psychoanalysis and Psychotherapy Psychological Phenomena and Processes Social and Cultural Anthropology Social History Soviet and Post-Soviet Studies Theory and Criticism Theory and Philosophy
34	The Closure of New Orleans' Charity Hospital After Hurricane Katrina: A Case of Disaster Capitalism Ott, Kenneth Brad 18 May 2012 (has links) Abstract Amidst the worst disaster to impact a major U.S. city in one hundred years, New Orleans’ main trauma and safety net medical center, the Reverend Avery C. Alexander Charity Hospital, was permanently closed. Charity’s administrative operator, Louisiana State University (LSU), ordered an end to its attempted reopening by its workers and U.S. military personnel in the weeks following the August 29, 2005 storm. Drawing upon rigorous review of literature and an exhaustive analysis of primary and secondary data, this case study found that Charity Hospital was closed as a result of disaster capitalism. LSU, backed by Louisiana state officials, took advantage of the mass internal displacement of New Orleans’ populace in the aftermath of Hurricane Katrina in an attempt to abandon Charity Hospital’s iconic but neglected facility and to supplant its original safety net mission serving the poor and uninsured for its neoliberal transformation to favor LSU’s academic medical enterprise. Charity Hospital New Orleans Hurricane Katrina disaster capitalism medical neoliberalism LSU Health Care Services Division American Politics Bioethics and Medical Ethics Community-Based Research Economics Emergency Medicine Health and Medical Administration Health Economics Health Policy Health Services Administration Medical Education Medicine and Health Medicine and Health Sciences Mental and Social Health Policy History, Theory, and Methods Political Economy Politics and Social Change Primary Care Psychiatric and Mental Health Public Health Public Policy Race and Ethnicity Social History Social Welfare Sociology Urban Studies Urban Studies and Planning

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