Thesis (M.Sc.)--Memorial University of Newfoundland, 2005. / Includes bibliographical references.

Dietary proteins from Atlantic salmon and cod have previously been shown to have antidiabetic effects. Since dietary proteins are digested into small peptides before being absorbed through the intestinal mucosa, it is reasonable to deduce that the antidiabetic effect is due to enzymatically-digested peptides rather than the proteins themselves. The aim of this study was to develop a protocol to recover peptides with antidiabetic effects from salmon and cod protein digests and then scale up and optimize the salmon protein hydrolysate production process for industrial-scale production. The peptide mixtures were screened using cell culture assays for insulin-modulating activities and were further fractionated and purified for the final identification. Total yields of salmon and cod protein hydrolysates (<1 kDa) as measured by Kjeldahl nitrogen were 16.9% and 40.1%, respectively. The production process used for the salmon protein hydrolysate (<1 kDa) showed good reproducibility and potential for the industrial-scale production.

Polymer composites are engineered materials widely being used and yet not completely understood for their dynamic response. It is important to fully characterize material properties before using them for applications in critical industries, like that of defense or transport. In this project, the focus is on determining dynamic fracture toughness property of fiber reinforced polymer composites by using a combined numerical- experimental methodology. Impact tests are conducted on Split-Hopkinson pressure bar with required instrumentation to obtain load-history and initiation of crack propagation parameters followed by finite element analysis to determine desired dynamic properties. Single edge notch bend(SENB) type geometry is used for Mode-I fracture testing and similarly end-notched flexure (ENF) type of geometry is proposed to test the samples for Mode-II type of fracture. Two different linear elastic fracture mechanics approaches are used- crack opening displacement and strain energy release rates. Dynamic fracture toughness values of around 50 MPa[square root of m] and 100 MPa[square root of m] in Mode-I, whereas, around 40 MPa[square root of m] and 6 MPa[square root of m] in Mode-II are observed for carbon-epoxy and fiberglass-epoxy composites respectively. To provide a better estimate of material response, Hashin damage model is employed which takes into account non-linear behavior of composites. As observed in previous studies, values estimated using a non-linear response of composite laminates are nearly three times as high, therefore, using a linear elastic material model could underestimate a material's capacity to sustain dynamic loads without failure. It is concluded that fracture initiation toughness property is rate dependent and is higher when subjected to dynamic loads. Microscopic examination of damaged samples and a higher value of dynamic fracture toughness for fiberglass-epoxy laminates as compared to carbon-epoxy laminates suggest that dynamic fracture toughness is also a function of many other variables like mode of fracture, dominant damage criteria, manufacturing process, constituent materials and their ratios.

This study was to investigate the removal efficiency and the feasibility of containing-EDTA solutions by O3 and O3/UV, advanced oxidation processes (denoted by AOPs). The operation parameters conducted in semi-batch reactor were as follows: ozone dose, pH, temperature and initial concentration of EDTA. The best mineralization and COD removal was found at pH= 9 when the pH values in O3 process was controlled at 3, 5, 7, 9 and 11. Addition of UV in O3 process for treating solutions containing EDTA was found not increasing the reaction rate but raising the COD and mineralization efficiency. In O3 process, the reaction rate was proportional to the ozone dose, it caused a higher mineralization. The higher the initial concentration of EDTA, the lower reaction rate, and the decreasing the mineralization was. Changing the temperature in reaction process was not obviously affected the removal of EDTA due to the lower activated energy found in O3 process. In O3/UV process, EDTA was decomposed very fast, but it still could not be mineralized the intermediates completely. The concentration of nitrate formed in this process was low. It is probably for high energy NH-containing bonds which is not easy break down by O3/UV. Thus, the major reactions in this process are the break of C-N bond, and followed by the break of C-H bond.

Thesis (Ph.D.)--Memorial University of Newfoundland, 2001. / Bibliography: leaves 370-399.

Thesis (M.Sc.), Memorial University of Newfoundland, 2000. / Bibliography: leaves 69-72.

Thesis (M.Sc.)--Memorial University of Newfoundland, 2002. / Restricted until October 2003. Bibliography: leaves 93-103.

The presence of great quantities of cod along much of the North American eastern seaboard was a significant factor in the early settlement and economy of the ares. European fishing fleets first appeared before 1510 (Innis, 1954). [...]

Dietary proteins from Atlantic salmon and cod have previously been shown to have antidiabetic effects. Since dietary proteins are digested into small peptides before being absorbed through the intestinal mucosa, it is reasonable to deduce that the antidiabetic effect is due to enzymatically-digested peptides rather than the proteins themselves. The aim of this study was to develop a protocol to recover peptides with antidiabetic effects from salmon and cod protein digests and then scale up and optimize the salmon protein hydrolysate production process for industrial-scale production. The peptide mixtures were screened using cell culture assays for insulin-modulating activities and were further fractionated and purified for the final identification. Total yields of salmon and cod protein hydrolysates (<1 kDa) as measured by Kjeldahl nitrogen were 16.9% and 40.1%, respectively. The production process used for the salmon protein hydrolysate (<1 kDa) showed good reproducibility and potential for the industrial-scale production.

Thesis (M. Sc.), Memorial University of Newfoundland, 1998. / Bibliography: leaves p. 71-84.