Diss. (sammanfattning) Stockholm : Karol. inst., 2002. / Härtill 5 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 4 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 5 uppsatser.

Thesis (M.S.)--University of Michigan, 1996. / Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 1996. / Includes bibliographical references.

Abstract The aim of this population-based cohort study was to evaluate the incidence and relative risk ratios of gynaecological cancers and the mortality of women with at least five children (GM women) compared to the average of Finnish women. We linked together the data of the Population Register (1974–1997), the Finnish Cancer Registry and the national cause-of death files of Statistics Finland (1974–2001) by using a personal identification code. The study population consisted of 86 978 GM women (1974–1997), including 3 752 women with at least 10 children (GGM women). Altogether 7 604 cancer diagnoses and 18 870 deaths were recorded. The incidence (SIR) of breast (0.55, 95% CI 0.52–0.58), endometrial (0.57, 95% CI 0.52–0.63) and ovarian cancer (0.64, 95% CI 0.55–0.73) decreased, and that of cervical cancer (1.13, 95% CI 0.98–1.29) increased in GM women. In multivariate analysis, the increase in parity from five to eight increased the protection against breast and endometrial cancer, but not in ovarian or cervical cancer. A young age at first birth decreased the breast cancer risk, while an older age at first birth decreased the risk for endometrial and cervical cancer. A short premenopausal delivery-free period and a long birth period were risk reducers in women who contracted endometrial cancer after menopause. The mortality (SMR) of breast (0.64, 95% CI 0.59–0.69), endometrial (0.68, 95% CI 0.56–0.80), ovarian cancer (0.68, 95% CI 0.60–0.75) as well as for dementia (0.80, 95% CI 0.72–0.84) decreased. The SMR of kidney (1.38, 95% CI 1.21–1.56) cancer increased in the GM group. The SMR of ischemic heart diseases (1.10, 95% CI 1.08–1.13) and diabetes mellitus (1.42, 95% CI 1.29–1.55) increased. The overall SMR of GM women was 5% less than expected (95% CI 0.94–0.95; deficit 949 deaths), but among GGM women it coincided with the national average (1.01, 95% CI 0.93–1.08). Multiparity affected the spectrum of diseases and causes of death in a specific way: the pregnancy-specific hormonal milieu is responsible for the low SIR and SMR of hormone-dependent cancers, and increased body weight is lightly responsible for the high SMR of cardiovascular and metabolic diseases. These observations advocate for delivering the first child at an age younger than 30 years and to start measures for careful weight control not only during and after pregnancies but even later and permanently.

Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005. / Härtill 4 uppsatser.

Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-12-15T17:09:35Z No. of bitstreams: 1 anselmoduarterodrigues.pdf: 719639 bytes, checksum: ff28645f45481af774073820323007eb (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-12-16T11:17:05Z (GMT) No. of bitstreams: 1 anselmoduarterodrigues.pdf: 719639 bytes, checksum: ff28645f45481af774073820323007eb (MD5) / Made available in DSpace on 2016-12-16T11:17:05Z (GMT). No. of bitstreams: 1 anselmoduarterodrigues.pdf: 719639 bytes, checksum: ff28645f45481af774073820323007eb (MD5) Previous issue date: 2010-03-25 / O objetivo do presente estudo foi analisar a tendência da mortalidade por câncer de mama e câncer de colo do útero em mulheres residentes no município de Juiz de Fora, Minas Gerais. Para tanto, utilizou-se a série histórica de óbitos do Sistema de Informação sobre Mortalidade (SIM) do Ministério da Saúde. Foram identificados os óbitos que tiveram como causa básica o câncer de mama e o câncer de colo do útero, incluído útero sem outra especificação, ocorridos no período de 1980 a 2006. Foram calculadas taxas anuais de mortalidade específicas por idade e padronizadas pela população mundial. Para análise de tendência, foram utilizados modelos de regressão em que as taxas de mortalidade foram consideradas variáveis dependentes e os anos variáveis independentes. Foram aplicados modelos de regressão polinomial e modelo de regressão linear segmentada (regressão joinpoint). A tendência das taxas de mortalidade foi considerada significativa quando o modelo de regressão polinomial considerado atingiu nível de significância de 5% (p < 0,05). Para regressão linear segmentada, foram utilizadas taxas de mortalidade log-transformadas e a análise estatística, testada por teste de permutação com descrição dos respectivos intervalos de confiança. O câncer de mama foi a principal causa de óbito entre as neoplasias malignas na população de mulheres residentes no município de Juiz de Fora, com a menor taxa anual de mortalidade no ano de 1997, equivalente a 10,0 por 100.000 mulheres e a maior taxa em 1999, 19,6 por 100.000. No mesmo período, para o câncer de colo do útero, foram observadas taxas que variaram de 3,6 no ano de 2003 a 12,5 por 100.000 em 1982. A análise de tendência pelo modelo de regressão polinomial mostrou queda na taxa de mortalidade por câncer de colo do útero (p=0,001) e tendência de crescimento da mortalidade por câncer de mama (p=0,035) ao longo dos anos da série. Por outro lado, a análise por regressão linear segmentada mostrou redução na taxa de mortalidade por câncer de colo do útero até o ano de 2001 com APC -4,2% (IC 95% -6,2: -2,1), com estabilização das taxas nos últimos anos da série, e não mostrou variação de tendência na mortalidade por câncer de mama. O comportamento da mortalidade por câncer de mama e colo do útero no município de Juiz de Fora sugere um processo de transição epidemiológica em andamento, representado por significativas taxas de mortalidade por doenças associadas a melhores condições socioeconômicas como o câncer de mama, e persistência de taxas elevadas por 7 tumores que geralmente guardam relação com a pobreza, como o câncer de colo do útero. / The aim of this study was to analyze the trends in mortality from breast cancer and cancer of the uterine cervix in women of the municipality of Juiz de Fora, Minas Gerais, Brazil. The death time-series of the Mortality Information System (Sistema de Informação Sobre Mortalidade – SIM) of the Brazilian Ministry of Health was used. Deaths having as the basic cause breast cancer and cancer of the uterine cervix, including uterus, part unspecified, occurring during the period 1980-2006, were identified. Age-related annual specific mortality rates were calculated and standardized according to the world population. Regression models, in which mortality rates were considered dependent variables and the years independent variables, were used for analysis of mortality trends. Polynomial regression and segmented linear regression (joinpoint) models were applied. Trends in mortality rate were considered significant when the polynomial regression model reached the 5% significance level (p < 0.05). For segmented linear regression, log-transformed mortality rates and permutation tested statistical analysis with description of the respective confidence intervals were used. Breast cancer was the main cause of death among malignancies in the population of women living in the municipality of Juiz de Fora, with the lowest mortality rate in 1997 (10/100,000) and the highest mortality rate in 1999 (19.6/100,000). During the same period, the mortality rates for cancer of the uterine cervix ranged from 3.6/100,000 in 2003 to 12.5/100,000 in 1982. Trend analysis by the polynomial regression model showed a decrease of mortality due to cancer of the uterine cervix (p=0.001) and an increase of mortality due to breast cancer (p=0.035) throughout the years of the series. On the other hand, segmented linear regression analysis showed a decrease in mortality due to cancer of the uterine cervix until 2001 (APC -4.2%; CI 95% -6.2: -2.1), with stabilization of the rates in the last years of the series, there being no variation in the mortality due to breast cancer. The behavior of the mortality due to breast cancer and cancer of the uterine cervix in the municipality of Juiz de Fora suggests an ongoing process of epidemiological transition, with significant mortality rates due to diseases associated with better socioeconomic conditions, such as breast cancer, and the persistence of high rates of tumors related to poverty, such as cancer of the uterine cervix.

Orientador: Glaucia Maria Bovi Ambrosano / Dissertação (Mestrado profissional) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-18T19:51:18Z (GMT). No. of bitstreams: 1 Franco_JoseLuizVieira_M.pdf: 1966190 bytes, checksum: 9efee402598d2c7ca59b34dcd81d0a4d (MD5) Previous issue date: 2011 / Resumo: Dentre todos os tipos, o câncer de colo do útero é o que apresenta um dos mais altos potenciais de prevenção e cura, chegando perto de 100%, quando diagnosticado precocemente. Neste trabalho avaliou-se a proporção de mulheres com resultados alterados nas Unidades da Região da Supervisão de Saúde da Penha (20 unidades) que fazem o acompanhamento preconizado pelo Ministério da Saúde e a proporção de Unidades com fluxos de acompanhamento corretos e como as unidades estão fazendo o acompanhamento destes exames alterados. Utilizou-se para isto a verificação da existência dos livros de registro de exames, seu preenchimento correto, e a coleta de dados de tempo e resultados destes exames. Os dados foram analisados por meio de estatística descritiva, tabelas de distribuição de frequências e análise de correlação de Spearman. Verificou-se que na amostra avaliada os indivíduos apresentaram em média 32 anos (Intervalo de confiança de 95%), maior prevalência de NIC (Neoplasia Intra Epitelial) I (79,3%) e o tempo entre coleta de exame e diagnóstico final de 91 a 123 dias. Encontraram-se apenas nove unidades em conformidade com Protocolos de Seguimento do Ministério da Saúde. Concluiu-se que a implantação de protocolos é fator preponderante para um melhor seguimento dos exames alterados de Papanicolaou / Abstract: Among all the cancer of the cervix is the one that presents the highest potential for prevention and cure, reaching close to 100% when diagnosed early. This study evaluated the proportion of women with abnormal results of the Units of the Region's health Penha Supervision (20 units) that are having follow-up recommended by the Ministry of Health and the proportion of units with proper monitoring flows and how the units are following up of abnormal tests. It was used for this verification of the existence of the records of examinations, your correct completion, and data collection time and results of these tests. Data were analyzed using descriptive statistics, frequency distribution tables and Spearman correlation analysis. It was found that individuals in the sample had an average of 32 years (confidence interval 95%), higher prevalence of NIC (Cervical Intraepithelial Neoplasms) I (79.3%) and the time between collection and examination of final diagnosis 91 and 123 days. We found only nine units in accordance with follow-up protocols of the Ministry of Health concluded that the implementation of protocols is an important factor for better tracking of abnormal results of Papanicolaou / Mestrado / Odontologia em Saude Coletiva / Mestre em Odontologia em Saúde Coletiva

Bakgrund: Sexualitet och sexuell hälsa är två begrepp som hör samman. Sexualitet innebär närhet och kontakt medan sexuell hälsa innebär att det ska vara tryggt och säkert att utföra sexuella aktiviteter. Cervix tillhör kvinnans inre reproduktionsorgan. Globalt sett är cervixcancer en av den vanligaste cancerformen bland kvinnor. Mortaliteten är högre i utvecklingsländer än industriländer. Humant papillomvirus, HPV, är en av de bidragande faktorer till cervixcancer där kirurgi, cytostatika och strålbehandling är olika typer av behandling. Ett cancerbesked kan ge upphov till reaktioner som påverkar både den fysiska och psykiska hälsan.  Syfte: Syftet var att belysa kvinnors sexuella hälsa efter diagnostisering av cervixcancer. Metod: Denna litteraturöversikt sammanställdes genom insamling av material från tidigare forskning inom ett vårdvetenskapligt kunskapsområde. Tio stycken vetenskapliga artiklar som berör cervixcancer och sexualitet ligger till grund för resultatet. Materialet granskades och analyserades enligt Fribergs metod för att slutligen sammanfattas i huvudteman och underteman i en litteraturöversikt.  Resultat: Resultatet presenteras i tre huvudteman; Fysiska aspekter, Psykiska aspekter och Sociala aspekter. Resultatet visade att kvinnans sexualitet och sexuella hälsa påverkas i samband med cervixcancer. Positiva upplevelser som uttrycktes var att kvinnor uppskattade sexuella aktiviteter mer efter sjukdomen och negativa upplevelser som rapporterades var att kvinnor inte vågade utföra sexuella aktiviteter där samlagssmärta var en orsak. Sexuella hinder påverkade den sexuella funktionen och skapade oro hos kvinnorna. Behandlingen av cervixcancer påverkade kvinnan genom olika kroppsliga förändringar och obehag vid samlag.  Diskussion: De fysiska aspekterna påverkar kvinnans sexualitet och identitet. Ett behov av kunskap kring cervixcancer relaterat till sexualitet kan urskiljas hos kvinnorna, där sjuksköterskans ansvar är att tillhandahålla kvinnorna med denna information. Sjuksköterskan kan ta hjälp av Virginia Hendersons behovsteori och Cancercentrums Vårdprogram. / Background: Sexuality and sexual health are two concepts that belong together. Sexuality means proximity and contact while sexual health means that it is safe and secure to perform sexual activities. Cervix is a part of women's inner reproductive organs. Cervical cancer is globally seen as one of the most common forms of cancer amongst women where pain is a late symptom of cervical cancer. Mortality is higher in developing countries than industrialized countries. Human papillomavirus, HPV is the most common cause of cervical cancer, where surgery, cytostatic and radiation therapy are different types of treatment. Cytological changes do not always mean cancer. Getting a cancer message can induce emotional reactions such as anxiety, anger and concern. At different coping strategies; Active and passive, the woman can adapt to the new life situation. A cancer diagnosis can develop reactions that affect both the physical and the mental health. Aim: The purpose was to highlight women’s sexual health after diagnosis of cervical cancer. Method: This literature review was compiled by collecting material from previous research within a healthcare knowledge area. Ten scientific articles related to cervical cancer and sexuality are the basis for the outcome. The material was reviewed and analyzed according to Fribergs method and finally summarized into mainthemes and subthemes in a literature review. Results: The result is presented in three main themes; Physical aspects, Mental aspects, and Social aspects. The results showed that cervical cancer affected women’s sexuality and sexual health. Positive experiences expressed by the women were an increased estimation on sexual activity after the disease. While negative experiences that were reported was a fear of performing sexual activities where dyspareunia was a cause. Sexual barriers affected the sexual function and created a concern among the women. The treatment of cervical cancer affected the woman through various bodily changes and discomfort during sexual intercourse.   Discussion: The physical changes that the woman experience is affecting her sexuality and identity. A need for knowledge about cervical cancer related to sexuality was noted in the women, where the nurse's responsibility is to provide women with this information. Virginia Henderson's behavior theory and the Cancer center care program may be a support for the nurse.