Global ETD Search

81	Electromagnetic field and neurological disorders Alzheimer´s disease, why the problem is difficult and how to solve it Lyttkens, Peter January 2018 (has links) No description available. Alzheimer oxidative stress EMF microwave VGCC ACh protein refolding APOE big data FINGER wifi DECT AChE DNA-damage mobile phone glucose metabolism demyelinating antioxidant defence defective proteins non thermal effects Alzheimer risk pathophysiology mechanism amyloid pathologies multifactor strategy diet exercise cognitive training vascular risk management exposure sleep disturbance circadian dysfunction neuropsychiatric symptom risk assessments Neurosciences Neurovetenskaper
82	Activating Developmental Reserve Capacity Via Cognitive Training or Non-invasive Brain Stimulation: Potentials for Promoting Fronto-Parietal and Hippocampal-Striatal Network Functions in Old Age Passow, Susanne, Thurm, Franka, Li, Shu-Chen 24 July 2017 (has links) (PDF) Existing neurocomputational and empirical data link deficient neuromodulation of the fronto-parietal and hippocampal-striatal circuitries with aging-related increase in processing noise and declines in various cognitive functions. Specifically, the theory of aging neuronal gain control postulates that aging-related suboptimal neuromodulation may attenuate neuronal gain control, which yields computational consequences on reducing the signal-to-noise-ratio of synaptic signal transmission and hampering information processing within and between cortical networks. Intervention methods such as cognitive training and non-invasive brain stimulation, e.g., transcranial direct current stimulation (tDCS), have been considered as means to buffer cognitive functions or delay cognitive decline in old age. However, to date the reported effect sizes of immediate training gains and maintenance effects of a variety of cognitive trainings are small to moderate at best; moreover, training-related transfer effects to non-trained but closely related (i.e., near-transfer) or other (i.e., far-transfer) cognitive functions are inconsistent or lacking. Similarly, although applying different tDCS protocols to reduce aging-related cognitive impairments by inducing temporary changes in cortical excitability seem somewhat promising, evidence of effects on short- and long-term plasticity is still equivocal. In this article, we will review and critically discuss existing findings of cognitive training- and stimulation-related behavioral and neural plasticity effects in the context of cognitive aging, focusing specifically on working memory and episodic memory functions, which are subserved by the fronto-parietal and hippocampal-striatal networks, respectively. Furthermore, in line with the theory of aging neuronal gain control we will highlight that developing age-specific brain stimulation protocols and the concurrent applications of tDCS during cognitive training may potentially facilitate short- and long-term cognitive and brain plasticity in old age. Alterung kognitives Training Dopamin fronto-parietales Netzwerk hippocampal-striatales Netzwerk neuronale Verstärkungsregelung transkranielle elektrische Stimulation Technische Universität Dresden Publikationsfonds aging cognitive training dopamine fronto-parietal network hippocampal-striatal network neuronal gain control transcranial electrical stimulation Technische Universität Dresden Publishing Fund ddc:610 rvk:XA 10000
83	Activating Developmental Reserve Capacity Via Cognitive Training or Non-invasive Brain Stimulation: Potentials for Promoting Fronto-Parietal and Hippocampal-Striatal Network Functions in Old Age Passow, Susanne, Thurm, Franka, Li, Shu-Chen 24 July 2017 (has links) Existing neurocomputational and empirical data link deficient neuromodulation of the fronto-parietal and hippocampal-striatal circuitries with aging-related increase in processing noise and declines in various cognitive functions. Specifically, the theory of aging neuronal gain control postulates that aging-related suboptimal neuromodulation may attenuate neuronal gain control, which yields computational consequences on reducing the signal-to-noise-ratio of synaptic signal transmission and hampering information processing within and between cortical networks. Intervention methods such as cognitive training and non-invasive brain stimulation, e.g., transcranial direct current stimulation (tDCS), have been considered as means to buffer cognitive functions or delay cognitive decline in old age. However, to date the reported effect sizes of immediate training gains and maintenance effects of a variety of cognitive trainings are small to moderate at best; moreover, training-related transfer effects to non-trained but closely related (i.e., near-transfer) or other (i.e., far-transfer) cognitive functions are inconsistent or lacking. Similarly, although applying different tDCS protocols to reduce aging-related cognitive impairments by inducing temporary changes in cortical excitability seem somewhat promising, evidence of effects on short- and long-term plasticity is still equivocal. In this article, we will review and critically discuss existing findings of cognitive training- and stimulation-related behavioral and neural plasticity effects in the context of cognitive aging, focusing specifically on working memory and episodic memory functions, which are subserved by the fronto-parietal and hippocampal-striatal networks, respectively. Furthermore, in line with the theory of aging neuronal gain control we will highlight that developing age-specific brain stimulation protocols and the concurrent applications of tDCS during cognitive training may potentially facilitate short- and long-term cognitive and brain plasticity in old age. info:eu-repo/classification/ddc/610 ddc:610
84	Självskattning av exekutiva funktioner vid kognitiv träning : En utvärdering av The behavior rating inventory of executive functioning - self report / Self Rating of Executive Functioning After Cognitive Training : An Evaluation of The Behavior Rating Inventory of Executive Functioning - Self Report Jakobsson, Erik, Stocke, Elin January 2015 (has links) Traditionellt utvärderas effekter av kognitiv träning med objektiva prestationsmått. Syftet med uppsatsen var att undersöka självskattad exekutiv funktion som ett alternativt mått för att utvärdera effekter av kognitiv träning. Som utfallsmått valdes The behavior rating inventory of executive functioning - self report (BRIEF-SR). Vidare användes blandad design med för- och eftermätning samt tre oberoende grupper. Gymnasieelever (n = 63) delades in i; aktiv träningsgrupp, aktiv placebogrupp och passiv kontrollgrupp. Tränings- och placebogruppen genomförde datoriserad kognitiv träning med respektive utan adaptiv svårighetsgrad. ANCOVA med arbetsminneskapacitet som kovariat visade inga signifikanta träningseffekter på självskattade exekutiva funktioner, oavsett grupptillhörighet. Sammantaget kan BRIEF-SR vara ett lämpligt instrument vid utvärdering av kognitiv träning när ekologisk validitet prioriteras. Resultaten diskuteras avseende inverkan av tid mellan för- och eftermätning, population och förväntanseffekter. / Performance based measures have been the Golden standard when evaluating effects of cognitive training. By using The Behavior Rating Inventory of Executive Functioning-Self Report (BRIEF-SR), this thesis aimed to explore self- rating scales as an alternative when evaluating effects of cognitive training. A sample of high school students (n = 63) and a mixed- effect model with pre- and post-measurements were chosen. The students were divided into three groups: active training, training with placebo or passive control. The two groups in training practiced with a computerized cognitive training program. The two training groups practiced with an adaptive and non-adaptive computer program, respectively. With working memory as covariate ANCOVA reported no significant effects on self-rated executive functions independent of group condition. In sum, if ecological validity is of priority BRIEF-SR can be considered when measuring effects following cognitive training. In addition the results are discussed with regards to time between pre- and post-measurements, population and effects of expectancy. / Effekter av kognitiv träning på skolprestationer och självreglering av beteende (dnr 1,2009/0 018,5-0) Self rating self measure executive functioning cognitive training self report BRIEF-SR ANCOVA transfer effects of training ecological validity placebo effects of placebo expectations objective performance measures working memory shifting attention inhibition updating självskattning exekutiva funktioner kognitiv träning self report BRIEF-SR ANCOVA arbetsminnesträning generalisering transfer utvärdering träningseffekter ekologisk validitet placeboeffekter placeboträning förväntning objektiva prestationsmått arbetsminne skifta uppmärksamhet inhibering uppdatering
85	Vybrané metody sociální práce s nesoběstačnými klienty ve zdravotnických zařízeních / The selected methods of social work with clients self - non sufficient in health care facilities Kiliánová, Hana January 2016 (has links) The main goal of the thesis entitled "The selected methods of social work with clients self-non sufficient in health care facilities" was to describe and to analyze methods used in activation of the elderly suffering from dementia. It draws a comparison of different settings and explores workers's attitude to the methods of activation. The text of the thesis was mapped out into five chapters. The first chapter was set into the context of old age and ageing. The second chapter is concerned with the issues of self-sufficiency and dependency of old age and other related issues. The topic of the third chapter is old age in relation with memory. It defines memory and memory disorders in the elderly suffering from dementia. The fourth chapter is crucial and gives an idea of non-pharmacological and other possible activities which are eligible for application in practice and are intended to reduce cognitive disorders of cognitive functions and behavior disorders. The theoretical part enters into research carried out in four facilities which care for clients with dementia. The research section is represented by a qualitative research where methods of a half structured interview and observation were opted for. The interviews were realized with eight practicing experts. The outcomes gathered from the...

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