We establish several new results about the ( n )-solvable filtration, [Special characters omitted.] , of the string link concordance group [Special characters omitted.] . We first establish a relationship between ( n )-solvability of a link and its Milnor's μ-invariants. We study the effects of the Bing doubling operator on ( n )-solvability. Using this results, we show that the "other half" of the filtration, namely [Special characters omitted.] , is nontrivial and contains an infinite cyclic subgroup for links with sufficiently many components. We will also show that links modulo (1)-solvability is a nonabelian group. Lastly, we prove that the Grope filtration, [Special characters omitted.] of [Special characters omitted.] is not the same as the ( n )-solvable filtration.

Le but de cette étude exploratoire est de déterminer si le test de concordance de script est un instrument capable de mesurer le raisonnement clinique d’étudiantes en formation et s’il peut déceler des différences entre le raisonnement clinique des novices et des expertes de la profession. Un TCS adapté au domaine des sciences infirmières et portant sur des champs particuliers de la pédiatrie a été administré à des candidates revendiquant différents niveaux d’expérience : des expertes du domaine (n=15), des infirmières (n=40) et des étudiantes de troisième année de formation (n=30). D’une durée de 20 minutes, le test a été pratiqué en ligne; il comptait 15 scénarios et 45 items au total. Les scores des étudiantes étaient significativement inférieurs aux scores des infirmières et des expertes. Le TCS est un instrument fiable et utile lorsqu’il s’agit de déterminer, en termes de raisonnement clinique, une différence de niveau entre la novice et l’experte.

Le but de cette étude exploratoire est de déterminer si le test de concordance de script est un instrument capable de mesurer le raisonnement clinique d’étudiantes en formation et s’il peut déceler des différences entre le raisonnement clinique des novices et des expertes de la profession. Un TCS adapté au domaine des sciences infirmières et portant sur des champs particuliers de la pédiatrie a été administré à des candidates revendiquant différents niveaux d’expérience : des expertes du domaine (n=15), des infirmières (n=40) et des étudiantes de troisième année de formation (n=30). D’une durée de 20 minutes, le test a été pratiqué en ligne; il comptait 15 scénarios et 45 items au total. Les scores des étudiantes étaient significativement inférieurs aux scores des infirmières et des expertes. Le TCS est un instrument fiable et utile lorsqu’il s’agit de déterminer, en termes de raisonnement clinique, une différence de niveau entre la novice et l’experte.

The n-solvable filtration of the link concordance group, defined by Cochran, Orr, and Teichner in 2003, is a tool for studying smooth knot and link concordance that yields important results in low-dimensional topology. We focus on the first two stages of the n-solvable filtration, which are the class of 0-solvable links and the class of 0.5-solvable links. We introduce a new equivalence relation on links called 0-solve equivalence and establish both an algebraic and a geometric characterization 0-solve equivalent links. As a result, we completely characterize 0-solvable links and we give a classification of links up to 0-solve equivalence. We relate 0-solvable links to known results about links bounding gropes and Whitney towers in the 4-ball. We then establish a sufficient condition for a link to be 0.5-solvable and show that 0.5-solvable links must have vanishing Sato-Levine invariants.

Im Katalog des Südwestverbunds besitzen zahlreiche Publikationen sowohl SWD-Schlagwörter und -ketten als auch Notationen der Regensburger Verbundklassifikation (RVK). An der Universitätsbibliothek Mannheim wurden auf dieser Datenbasis automatische Korrelationen zwischen SWD und RVK generiert, die im Rahmen einer Bachelorarbeit an der Hochschule der Medien Stuttgart analysiert wurden. Im Vortrag werden die Ergebnisse der Analyse vorgestellt und Überlegungen zu möglichen praktischen Anwendungen solcher Korrelationen angestellt.

Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of the breast is a widely used non-invasive approach to gather information about the underlying physiology of breast tumors. Recent studies indicate that breast tumor heterogeneity may reflect the presence of different levels of cellular aggressiveness or habitats within the tumor. This heterogeneity has been correlated to the variations in the contrast enhancement patterns within the tumor apparent on gadolinium-enhanced DCE-MRI. Although pathological and qualitative (based on contrast enhancement patterns) studies suggest the presence of clini- cal and molecular predictive tumor sub-regions, this has not been fully investigated in the quantitative domain. The new era of cancer imaging emphasizes the use of Radiomics to provide in vivo quan- titative prognostic and predictive imaging biomarkers. Thus Radiomics focuses on apply- ing image analysis techniques to quantify tumor radiographic properties to create mineable databases from radiological images. In this research work, the Radiomics approach was ap- plied to develop a novel computer aided diagnosis (CAD) model for quantifying intratumor heterogeneity not only within the tumor as a whole, but also within tumor habitats with an intent to build predictive models in breast cancer. The process of building these predictive models started with 2-D tumor segmentation followed by habitat extraction (based on vari- ations in contrast patterns and geometry) and textural kinetic feature extraction to quantify habitat heterogeneity. A new correlation based random subspace ensemble framework was developed to evaluate the textural kinetics from the individual tumor habitats. This new CAD framework was applied to predict two clinical and prognostic factors: Axillary lymph node (ALN) metastases and Estrogen receptor (ER) status. An AUC of more than 0.8 was achieved for classifying breast tumors based on number of ALN involvement. The highest AUC of 0.91 was achieved for classifying tumors with no ALN metastases from tumors with 4 or more ALN metastases. For classifying tumors based on ER status the highest AUC of 0.87 was achieved. These results were acquired by utilizing the textural kinetic features from the tumor habitat with rapid delayed washout. The results presented in this work showed that the heterogeneity within the tumor habitats which showed rapid contrast washout in the delayed phase, correlated with aggressive cellular phenotypes. This work hypothesizes that successfully quantifying these prognostic factors will prove to be clinically significant as it can improve the diagnostic accuracy. This, in turn, will im- prove the breast cancer treatment paradigm by providing more tailored treatment regimens for aggressive tumors.

Western herbal medicine (WHM) is a whole system of medicine that is based on beliefs and practices that evolved distinct from conventional Western medicine. Practitioners of WHM use naturally-occurring crude plant materials, such as roots or flowers with little processing for persons with chronic disease. Herbal medicines are formulated and designed for each person's unique symptom variations, energetic profile, cause and supporting mechanisms of the health issue. This approach to herbal medicine is not explicated in the literature and contrasts the use of highly-processed herb products in a one-size-fits-all approach that fails to reflect WHM as a whole complex system. The purpose of this study was to develop a grounded theory explaining the basic social psychological process WHM practitioners use to formulate plant medicines for individuals. Data were collected from a theoretical sample of 17 North American WHM practitioners contributing a total of 39 interviews and analyzed using the constant comparison method. The process of Personalizing Western Herbal Medicine consists of five steps with a decision-making subprocess of five steps. The core concept of Weaving a Tapestry of Right Relationships explains what practitioners do when Personalizing Western Herbal Medicine. Right relationship is emergent coherence and accounts for wholeness as the relationship of the parts and weaves through connecting each step in Personalizing Western Herbal Medicine. Creating Concordance describes right relationship between the person and the herbal medicine. Concordance is achieved when an herbal medicine fits the whole person and there is a personal shift or restoration of dynamic equilibrium.

Baigiamajame magistro darbe nagrinėjama Lietuvos Respublikos vairuotojų rengimo sistemos įtaka eismo keliais efektyvumui bei eismo jais saugumui, tam pasitelkus ekspertinių tyrimų metodus. Išanalizuota užsienio šalių patirtis šioje srityje bei eismo saugumą reglamentuojantys dokumentai. Išnagrinėti ir susisteminti veiksniai, turintys įtakos vairuotojo patikimumui. Šių veiksnių įtaka: eismo saugumui tirti naudotas respondentų anketinis apklausos metodas. / The final MA thesis deals with the influence of driver’s preparation system in the Republic of Lithuania to efficiency of traffic on roads and safety, by using experimental methods of research. The paper analyzed experience of foreign countries in this field and documentation regulating traffic safety. Analysis was also made for systematic factors having influence on the driver’s reliability. Impact of these factors: a questionnaire survey was used to investigate traffic safety as understood by the respondents.

Dans le présent travail il s’agira du mode de l’indicatif français, notamment de la concordance des temps de l’indicatif et son transfert vers le lituanien. Donc, l’objectif de notre mémoire est l’étude du système de l’indicatif du français et son transfert en lituanien. / Mūsų darbo tikslas yra išstudijuoti prancūzų kalbos tiesioginę nuosakos laikus ir jų vertimą į lietuvių kalbą. Kalbant apie tiesioginę nuosaką reikėtų pasakyti, kad vien šios nuosakos formos jau gali išreikšti laiko sąvoką. Taip pat reikėtų paminėti, kad specifinis prancūzų kalbos gramatikos bruožas yra laikų derinimas. Laikų derinimu vadiname atitikmenį, kuris reikalingas atliekamų veiksmų suvokimui ir chronologijai, kurie egzistuoja sudėtiniame sakinyje išdėstant veiksmažodžių laikus tarp pagrindinio ir šalutinio sakinio. Norint suprasti, kaip veikia laikų derinimo mechanizmas, reikia stebėti, kaip keičiasi šalutinio sakinio veiksmažodžiai, kada pakinta pagrindinio sakinio veiksmažodžių laikas. Taip galima išskirti dabarties ir praeities veiksmažodžių laikų derinimo planus. Vis tik nereikėtų suprasti laikų derinimo tik kaip metodo, kai šalutinio sakinio laikų vartojimas priklauso nuo pagrindinio sakinio laikų vartojimo. Laikų derinimo sąvoka yra daug platesnė. Sakykim, derinant pasakojimo laikus, reikia atkreipti dėmesį ne tik į atitinkamo laiko plano laikų derinimą, bet ir į pasakojimo prasmę, į tai, ką norima pasakyti. / Dans le présent travail il s’agira du mode de l’indicatif français, notamment de la concordance des temps de l’indicatif et son transfert vers le lituanien. Donc, l’objectif de notre mémoire est l’étude du système de l’indicatif du français et son transfert en lituanien.

Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal