This study explored doctor of physical therapy (DPT) students’ attitudes, perceived knowledge, and perceived competence specific to social and structural determinants of health (SDOH). Current students in a DPT program housed within a college of public health in an urban research institution served as the participants for this research. The primary purpose of this study was to explore students’ self-evaluation and perceptions of competence with SDOH in hopes of gaining insight into elements of their education that contributed to their preparedness and/or what strategies and resources are needed to foster competence in this area. A secondary aim of this study was to explore how individual student factors and curricular factors impact students’ awareness of SDOH. A mixed methods study design employed bivariate and multivariate analysis of participants’ responses to self-report Likert scale survey questions and analysis of semi-structured interviews using qualitative description and phenomenological principles. Quantitative data analysis revealed differences in perceived skills competence based on cohort (year one, two, or three in the program) with first-year students demonstrating lower perceived competence. Analysis of attitudes and knowledge demonstrated that all participants held a positive perspective regarding the importance of SDOH as well as perceived foundational knowledge for this content. Quantitative analysis also detected subtle differences in specific sample beliefs and behaviors based on demographic variables such as gender identity, race, and first-generation student status. Qualitative data supported the quantitative findings with participants articulating specific elements of their identities and the DPT curriculum that contributed to their understanding of SDOH. An iterative coding process identified two primary themes that corresponded to the research aims: 1) Learners’ perceived importance of social and structural determinants of health and factors that impact how to address them; and 2) Learning about social and structural determinants of health: What learners bring with them and what they gain throughout the curriculum. These findings shed light on the elements of this educational program that foster students understanding of SDOH and the types of experiences that help clinical learners appreciate the impact of these upstream drivers of health for patients and populations. / Policy, Organizational and Leadership Studies

Cardiovascular diseases (CVDs) are the leading cause of death and disability around the world. The purpose of this thesis is to investigate the impact of socio-environmental determinants of CVDs at the neighbourhood scale in order to inform actionable interventions, which may lead to large-scale reductions in preventable CVDs. Drawing on 2411 surveys carried out in Toronto, Canada, this thesis employs multilevel models to estimate the magnitude of socio-environmental influences on the risk of CVD while adjusting for individual-level risk factors. To advance current research methodology, strategies and innovations were developed to 1) improve the characterization of neighbourhoods by empirically testing a full range of socio-environmental influences; 2) account for non-residential exposures by including a combined analysis of work and home contexts; 3) account for variations in the duration of exposure through the use of time-weighted models; 4) deal with problem of spatial data aggregation by developing and testing a novel method of neighbourhood zone design, and 5) account for the spatial scales of different socio-environmental determinants by modeling at multiple scales. The thesis demonstrated that land use decisions are inextricably public health decisions. It found that living in neighbourhoods with inadequate access to food stores and areas for physical activity, burdened by violent crimes and fast food restaurants, and over-dependent on automobiles (leading to air pollution), with a high level of noise may significantly increase the risk of CVDs, over and above individual-level risks. The thesis also found that working in neighbourhoods that are socio-economically disadvantaged or have high-traffic may significantly increase CVD risk. The thesis developed and demonstrated novel methods to reduce the measurement error of neighbourhood exposures through 1) the use of “amoeba buffers” to improve neighbourhood zone design to better reflect participants’ local neighbourhoods and 2) the use of duration of exposure weights to adjust for individual differences in the time spent across different contexts. Finally, it found that the significance of socio-environmental factors depends on the scale of data aggregation; thus, investigation of multiple scales may be required to identify the relevant scale that matches the specific contextual factor in future research.

Cardiovascular diseases (CVDs) are the leading cause of death and disability around the world. The purpose of this thesis is to investigate the impact of socio-environmental determinants of CVDs at the neighbourhood scale in order to inform actionable interventions, which may lead to large-scale reductions in preventable CVDs. Drawing on 2411 surveys carried out in Toronto, Canada, this thesis employs multilevel models to estimate the magnitude of socio-environmental influences on the risk of CVD while adjusting for individual-level risk factors. To advance current research methodology, strategies and innovations were developed to 1) improve the characterization of neighbourhoods by empirically testing a full range of socio-environmental influences; 2) account for non-residential exposures by including a combined analysis of work and home contexts; 3) account for variations in the duration of exposure through the use of time-weighted models; 4) deal with problem of spatial data aggregation by developing and testing a novel method of neighbourhood zone design, and 5) account for the spatial scales of different socio-environmental determinants by modeling at multiple scales. The thesis demonstrated that land use decisions are inextricably public health decisions. It found that living in neighbourhoods with inadequate access to food stores and areas for physical activity, burdened by violent crimes and fast food restaurants, and over-dependent on automobiles (leading to air pollution), with a high level of noise may significantly increase the risk of CVDs, over and above individual-level risks. The thesis also found that working in neighbourhoods that are socio-economically disadvantaged or have high-traffic may significantly increase CVD risk. The thesis developed and demonstrated novel methods to reduce the measurement error of neighbourhood exposures through 1) the use of “amoeba buffers” to improve neighbourhood zone design to better reflect participants’ local neighbourhoods and 2) the use of duration of exposure weights to adjust for individual differences in the time spent across different contexts. Finally, it found that the significance of socio-environmental factors depends on the scale of data aggregation; thus, investigation of multiple scales may be required to identify the relevant scale that matches the specific contextual factor in future research.

Inflytande och delaktighet utgör det första målområdet i svensk folkhälsopolitik och anses vara grundläggande för människors hälsa. Sambandet mellan delaktighet och hälsa är etablerat, men framför allt bland vuxna. Hur sambandet mellan delaktighet, och i synnerhet hur olika komponenter av delaktighet, och hälsa ser ut bland gymnasieungdomar är inte lika väl undersökt. Syftet med studien var att dels undersöka samband mellan delaktighet i form av vilja att påverka frågor i kommunen samt föreningsaktivitet och självskattad hälsa bland gymnasieungdomar, dels hur sambanden förändras vid kontroll av andra faktorer. Studien hade en tvärsnittsdesign och baserades på befolkningsenkäten Liv och hälsa ung i Uppsala län från 2013. Urvalet bestod av 2453 gymnasieelever. Sambanden analyserades med hjälp av binär logistisk regression. Att vilja påverka frågor i kommunen hade ett svagt samband med självskattad hälsa, men vid justering av sociodemografiska, sociala samt skolrelaterade faktorer försvann sambandet. Föreningsaktivitet var däremot signifikant associerat med självskattad hälsa, där föreningsinaktivitet var förknippat med högre odds för självskattad ohälsa. Faktorer närmare ungdomarnas liv hade emellertid starkare samband med deras självskattade hälsa. Riktningen i sambanden kunde inte fastslås, men baserat på tidigare forskning, indikerar resultatet att föreningsaktivitet kan vara ett område att rikta folkhälsoinsatser mot. Både som ett sätt att främja hälsa, men också för att öka demokratist deltagande och inflytande. / Influence and participation is the first target area in the Swedish public health policy and is considered essential to people’s health. The link between participation and health is established, but especially among adults. How participation, and in particular how various components of participation, are related to health among high school students is not as well investigated. The aim of the study was partly to investigate if participation in terms of wanting to influence issues of the municipality and also engagement in different associations relate to self-rated health among high school students, partly how the relationships change when adjusting for other factors. The study had a cross-sectional design and was based on the population survey Liv och hälsa ung in Uppsala County from 2013. The study population consisted of 2453 high school students. The correlations were analysed using binary logistic regression. Wanting to influence issues in the municipality had a weak correlation with self-rated health, and when adjusting for socio-demographic, social and school-related factors, the relationship disappeared. Engagement in an association, however, was significantly associated with self-rated health. Not being engaged in an association was associated with higher odds of self-rated health less then good, although factors closer to the adolescents had a stronger relationship with their self-rated health. The direction of the relationship could not be confirmed, but based on previous research, the results suggest that public health initiatives aimed at increasing the involvement in associations may be relevant, both as a step to promote health and to increase democratic participation and influence.

The purpose of this dissertation was to explore the mechanism of association between social determinants of health (SDH), particularly limited health literacy, and disparate outcomes related to cardiovascular disease in vulnerable populations. Specific aims were to 1) compare quality of life (QOL), anxiety, and depressive symptoms between genders in implantable cardioverter defibrillator (ICD) recipients; 2) examine the association between multi-morbidity burden and QOL; 3) determine whether health literacy levels independently predict CVD risk in the male prison population; 4) examine the relationship between health literacy and decisiveness regarding end of life (EOL) choices, and 5) examine SDH as predictors of perceived poor health status in ICD recipients. Specific aim one was addressed by analysis of data collected from individuals in the Swedish ICD and Pacemaker Registry. Multiple linear regression was used to determine predictors of anxiety, depression, and quality of life in men and women. A higher prevalence of anxiety symptoms in women was noted with no differences in depressive symptoms noted between the genders. The majority of the variance in the predictive models for QOL was explained by the addition of the psychosocial variables for both genders. Specific aim two was addressed by analysis of data collected from individuals in the Swedish ICD and Pacemaker Registry. Logistic regression was used to determine predictors of QOL. Greater multi-morbidity burden was associated with lower QOL in ICD recipients. Specific aim three was addressed by analysis of data collected from male inmates enrolled in a bio-behavioral educational and counselling intervention program to reduce CVD risk. Nonlinear regression was used to determine whether health literacy was an independent predictor of CVD risk while controlling for social and clinical variables. Inmates with adequate levels of health literacy had lower ten year CVD risk profiles than those inmates with inadequate health literacy. Specific aim four was addressed by analysis of data collected from ICD recipients. Multinomial regression was used to determine predictors of decisiveness regarding EOL choices. Within the context of terminal illness, health literacy and race were found to be predictors of decisiveness regrading generator replacement while gender was found to be a predictor of decisiveness regarding the withdrawal of defibrillation therapy. Specific aim five was addressed by analysis of data collected from ICD recipients. Logistic regression was used to determine predictors of perceived poor health status. Residential status in the Central Appalachian region of Kentucky, not working outside the home, higher levels of health literacy, and comorbid depression were predictors of perceived poor/very poor health status.

Introdução: O Projeto Viva Seu Bairro (PVSB) foi uma iniciativa desenvolvida em seis regiões urbanas da cidade de Campo Grande MS, no período de 2001 a 2004, nas áreas de maior risco social, identificadas pelas equipes de agentes comunitários de saúde e saúde da família. O projeto teve como objetivo a redução das desigualdades sociais por meio de ações que atuaram sobre Determinantes Sociais da Saúde (DSS). Objetivo: A pesquisa buscou conhecer a relação entre o PVSB e os determinantes sociais da saúde, bem como identificar a presença da participação social e da intersetorialidade nas ações desenvolvidas. Material e Métodos: Trata-se de pesquisa de abordagem qualitativa. Foram realizadas entrevistas individuais com gestores da administração municipal e com técnicos da Unidade Técnica Central (UTC), responsável pelo gerenciamento do projeto. Seis grupos focais foram realizados, um em cada região urbana que teve a implementação da iniciativa, com representantes dos Conselhos Regionais Urbanos (CRU). Além disto, foi feita a análise de documentos relacionados ao PVSB. Para a análise dos dados, utilizou-se a análise de conteúdo, por meio da análise temática com a triangulação dos dados obtidos. Resultados: Os resultados da pesquisa apontam uma série de ações que incidiram sobre as condições materiais e psicossociais nas quais as pessoas vivem e trabalham, como proposto pelo modelo adotado nas recomendações do Relatório Final da Comissão Nacional sobre Determinantes Sociais da Saúde (2008). As mais descritas pelos participantes foram as que visaram assegurar saneamento básico, habitação adequada, emprego, serviços de saúde e de educação de qualidade. Verificou-se o protagonismo do setor saúde no desencadeamento da iniciativa. Conclusões: A participação social foi fortalecida na cidade durante e após a iniciativa. Quanto à intersetorialidade, houve a busca por parcerias e o reconhecimento, por parte dos representantes de governo, da necessidade de se implementar redes sociais, o que, no entanto, não se institucionalizou como práticas da administração municipal. A discussão sobre a sustentabilidade ocorreu de modo insuficiente e a avaliação da iniciativa começou um ano e meio após o seu início, o que comprometeu a avaliação de processo. Os participantes da pesquisa reconheceram que o PVSB interferiu na melhoria da qualidade de vida da população local. Conclui-se que o PVSB configurou-se como iniciativa do campo da promoção da saúde, atuou sobre os DSS, fortaleceu os mecanismos de participação nos CRU e buscou mecanismos de ação intersetorial / Introduction - The Project \"Viva Seu Bairro\" (PVSB) was an initiative developed in six urban regions of the city of Campo Grande - MS, from 2001 until 2004, in the areas of greater social risk, identified by the teams of community health and family health agents. The project had as its aim to reduce the social inequalities through actions, which acted on the Social Determinants of Health (SHD). Objective - The research tried to know the relation between PVSB and the Social Determinants of Health, as well as to identify the presence of the social participation and the intersectoriality in the developed actions. Material and Methods - It is about a research of qualitative approach. Individual interviews were performed with managers of the municipal administration and with technicians from Central Technical Unity, responsible for the project administration. Six focal groups were carried out, one in each urban region that had the initiative implementation, with representatives from the Urban Regional Councils. Moreover, an analysis of the documents related to PVSB was done. The Content Analysis was used for the analysis of the data through the thematic analysis and then the triangulation of the obtained data. Results - The results of the research point out a series of actions that occurred to the material and psychosocial conditions in which the people lived and worked, as proposed by the model adopted in the recommendations of the Final Report of the National Commission on Social Determinants of Health (2008). The items most described by the participants were the ones that targeted to assure basic sanitation, appropriate dwelling, employment, health and education services of quality. It was verified the prognostic of the health sector in the breaking of the initiative. Conclusions - The social participation was strengthened in the city during and after the initiative. In relation to the intersectoriality, there was a search for partnerships and the recognition, from the government representatives, of the necessity to implement social nets, which however, was not institutionalized as a practice in the municipal administration. The discussion about the sustainability occurred in an insufficient way and the initiative evaluation started one year and a half after its beginning, which compromised the process of evaluation. The research participants recognized that PVSB interfered in the improvement of the local population life quality. It was concluded that PVSB configured as an initiative in the field of health promotion, acted on SHD, strengthened the mechanisms of participation in the CRU and looked for mechanisms of intersectorial action.

Introdução: Dentre as várias áreas, abordagens e temas que compõem a Saúde Pública, a Promoção da Saúde constitui-se como um dos mais estabelecidos o que indica a pertinência de reflexão sobre sua produção. E dentre as linhas de pesquisa na área de Promoção da Saúde, nos últimos anos, tem se destacado o tema de Determinantes Sociais de Saúde, essa preocupação expressa por essa linha de pesquisa e atuação sobre os Determinantes Sociais de Saúde (DSS) assim como as propostas de promoção da saúde remetem necessariamente à reflexão sobre a dinâmica social visto que estão voltadas para a transformação das condições de vida. Objetivo: Esse estudo teve por objetivo identificar a produção da pesquisa em DSS na Faculdade de Saúde Pública da Universidade de São Paulo, no período de 2004 a 2008, e apontar as áreas de interesse e tendências desse campo de estudo. Metodologia: A metodologia consistiu em uma revisão bibliográfica de estudos sobre DSS, realizada a partir de um levantamento de dados baseado na consulta às seguintes bases de dados: BVS (Biblioteca Virtual em Saúde), SciELO (Scientific Electronic Library Online) e banco de tese da Capes. Os indexadores para a pesquisa foram selecionados segundo os Descritores em Ciência da Saúde (DeCS). Resultados: Dentre os diversos determinantes sociais de saúde encontrados durante a coleta de dados, os mais citados foram: inclusão social, segurança, justiça social, transporte, qualidade de vida, modelos de atenção à saúde, educação, lazer, ambiente de trabalho, equidade, distribuição de renda, recursos sustentáveis, ecossistema saudável, stress e saneamento. Deu-se preferência pelos resultados que se referiram diretamente ao tema da pesquisa sobre Determinantes Sociais de Saúde, resultados esses que foram classificados por ano, tipo de publicação: teses, dissertações, artigos de periódicos e por classificação de determinantes sociais de saúde. Conclusão: Verificou-se que a produção cientifica com Determinantes Sociais de Saúde na Faculdade de Saúde Pública USP tem crescido continuamente nesses últimos anos e que a maioria dos trabalhos está voltada para o estudo sobre as iniquidades em saúde seguido, de estudos sobre o empoderamento e a qualidade de vida / Introduction: Among the various areas, approaches and themes that compose the Public Health, Health Promotion was established as one of the most established which indicates the relevance of reflection on their production. And among the lines of research in the area of Health Promotion, in recent years has highlighted the topic of Social Determinants of Health, this concern expressed by this line of research and action on the Social Determinants of Health (SDH) as well as proposals for health promotion necessarily refer to a reflection on the social dynamics as they are geared towards the transformation of living conditions. Objective: This study aimed to identify the production of research in SDH at the School of Public Health, University of São Paulo in the period 2004 to 2008, and point out areas of interest and trends of this field of study. Methodology: The methodology involved a literature review of studies in SDH. Data collection was based on consultation with the following databases: BVS (Virtual Library in Health), SciELO (Scientific Electronic Library Online) and CAPES thesis database. The indices for the study were selected according to the Health Sciences Descriptors (DeCS). Results: Among the many social determinants of health found during the data collection, the most cited were: social inclusion, security, social justice, transportation, quality of life, models of health care, education, leisure, work environment, fairness and distribution in income, resources sustainable, healthy ecosystem, stress and sanitation. It was given preference for results that are reported directly to the research theme on Social Determinants of Health, these results were sorted by year, type of publication: theses, dissertations, journal articles and for classification of social determinants of health. Conclusion: It was found that the scientific production with the Social Determinants of Health in the School of Public Health - USP has grown steadily in recent years and that most work is directed toward the study of inequities in health, followed by studies on the empowerment and quality of life

If there is one thing that policy makers at the World Health Organisation (WHO) and residents of the South African township of Langa are likely to agree on, it is that ‘just sitting’ is not good for you. The positions from which they approach this conclusion however differ profoundly. This research investigates different conceptualisations of physical activity, health, and wellbeing, and the implications of these differences for policy on the prevention of noncommunicable diseases (NCDs) in low and middle income countries, taking South Africa as a case study. With four out of five deaths from diseases such as diabetes, heart disease and stroke now occurring in low and middle income countries, prevention, of what have been termed ‘NCDs’, in these countries is rising rapidly up the global public health agenda. Physical activity is one of the four primary risk factors which have been identified as intervention targets, but there is an acknowledged paucity of research which helps us to understand how physical activity, and inactivity, are conceptualised in low and middle income country contexts. As a result the evidence base for design of physical activity policy interventions to address NCDs is also weak. The global discourse recognises the determinants of health as socially embedded, but struggles with what this means for policy on prevention. This study explores the detail of this social embeddedness by way of ethnographic research into wellbeing, health and physical activity carried out in a South African township, and juxtaposes this with conceptualisation of these same themes emerging from a review of academic and policy-oriented literature on the prevention of NCDs in low and middle income countries. The struggles of local research groups to reconcile the demands made on them from these very different worlds are explored, and strategies for addressing the specifics of NCD prevention without abstracting health from the broader context of the person or society are discussed. The research is theoretically informed by work on wellbeing in developing countries.

Cette thèse s’intéresse à la contribution des expositions professionnelles —chimiques, biomécaniques, et psychosociaux—tout au long de la vie dans les inégalités sociales de santé liés au vieillissement. Les trois papiers de la thèse essaient de combler les lacunes dans les connaissances sur les effets à long terme des expositions professionnelles et la contribution des expositions individuelles et conjointes dans ces inégalités. Le premier papier cherche à savoir si le niveau d’éducation atteint dans l’enfance modifie l’effet de l’exposition professionnelle aux solvants au cours de la carrière sur la fonction cognitive après 55 ans.. Nous avons trouvé que l’effet de l’exposition aux solvants sur la fonction cognitive était différent selon le niveau d’éducation.. Le deuxième papier discute les effets combinés des expositions biomécaniques et psychosociaux au cours de la vie professionnelle sur la santé physique et fonctionnelle après la retraite. Nous avons trouvé qu’une forte exposition à la fois aux risques physiques et psychosociaux au cours de la vie active est associée à une capacité fonctionnelle bien plus faible après la retraite que l’exposition à un seul type de risques. Aussi, l’effet était différent chez les hommes et chez les femmes. Le troisième papier est un papier méthodologique qui discute des alternatives aux formes longues des échelles généralement utilisées pour évaluer les expositions biomécaniques au travail. Nous avons cherché à vérifier si la question « Trouvez-vous votre travail fatiguant physiquement?» pourrait être une mesure de substitution acceptable pour évaluer des expositions détaillées.. Nous avons comparé la mesure à un item à une mesure plus complète de 38 expositions spécifiques dans huit domaines. Nous avons trouvé que la mesure à un item était plus valide chez les participants fortement exposés à des contraintes biomécaniques de travail. En somme, cette thèse a montré que les expositions professionnelles peuvent à la fois exacerber les disparités existantes en matière de santé et les perpétuer au delà de la retraite. / This dissertation focuses on how occupational exposures throughout the lifecourse—chemical, physical, and psychosocial—contribute to social patterns in aging outcomes, addressing the gap in knowledge about lasting effects of occupational exposures and the contribution of individual and combined exposures to social patterns in aging. The first paper explores whether childhood educational attainment modifies effects of occupational solvent exposure during the career on cognitive function after age 55. We found differential effects of solvent exposure on cognition by educational attainment. The second paper looks at combined physical and psychosocial exposures during working life and effects on physical health and functioning after retirement. This paper finds that high exposure to both physical and psychosocial hazards at work is associated with worse functional capacity in retirement than exposure to either one separately; the pattern of this relationship differs for men and women. The third paper is a methodology paper exploring alternatives to extensive testing batteries often used to evaluate physical workplace exposures. We tested whether the question “Do you find your work physically strenuous?” was an acceptable proxy measure for more detailed exposure assessments by comparing the measure to a comprehensive self-report measure of 38 specific biomechanical strains across eight domains. We found that the measure was most valid in the populations that were most highly exposed to physical strains at work. In general, this dissertation found that occupational exposures can exacerbate existing disparities in health and perpetuate disparities into and beyond retirement.

Within and across all societies, some people live longer and healthier lives than others. Although many of us intuitively think of health as a very important good, general theories of justice have hitherto paid little attention to its distribution. This is a thesis about what we owe to one another, as a matter of justice, in view of our unequal levels of health. The first part of the thesis addresses the problem of social justice in health. I argue that the basic institutional framework of society must be arranged so as to ensure an egalitarian distribution of the 'social bases of health,' that is, the socioeconomic conditions that shape our opportunities for a healthy life. Inequalities in health, including those caused by differences in individual lifestyles, are only fair when people have been given fair opportunities. This egalitarian approach to the social bases of health must be complemented by a sufficientarian concern for meeting all basic health needs, regardless of whether these originate in unfair social arrangements. The second part of the thesis takes up the problem of global justice in health. Although I argue against the idea that domestic principles of justice can be simply replicated on a global scale, I emphasise the fact that there are a number of international institutions and practices that shape people's opportunities for health. One of these is the state system - the division of the world into sovereign states - which I argue grounds the idea of the human right to health. I also examine two more specific examples of global practices that contribute to global inequalities in health, namely global trade in tobacco and the global labour market for healthcare workers. Both of these, I suggest, must be restricted in light of their impact on health levels worldwide.