CAMARÃO, Diego de Lucena. Propriedades difusivas de sistemas clássicos confinados. 2011. 79 f. Dissertação (Mestrado em Física) - Programa de Pós-Graduação em Física, Departamento de Física, Centro de Ciências, Universidade Federal do Ceará, Fortaleza, 2011. / Submitted by Edvander Pires (edvanderpires@gmail.com) on 2015-04-28T21:29:36Z No. of bitstreams: 1 2011_dis_dlcamarao.pdf: 2441556 bytes, checksum: ff4cb229929b646cece7ef667144d79d (MD5) / Approved for entry into archive by Edvander Pires(edvanderpires@gmail.com) on 2015-04-29T17:54:40Z (GMT) No. of bitstreams: 1 2011_dis_dlcamarao.pdf: 2441556 bytes, checksum: ff4cb229929b646cece7ef667144d79d (MD5) / Made available in DSpace on 2015-04-29T17:54:41Z (GMT). No. of bitstreams: 1 2011_dis_dlcamarao.pdf: 2441556 bytes, checksum: ff4cb229929b646cece7ef667144d79d (MD5) Previous issue date: 2011 / Nesta dissertação, fizemos um estudo das propriedades difusivas de um sistema de partículas clássicas carregadas em canais quasi-unidimensionais. Mais especificamente, no Capítulo 2, apresentamos uma revisão do problema da difusão e do movimento browniano. Mostramos que as abordagens de Einstein e de Langevin para o movimento browniano são equivalentes no limite de tempos longos. Isto foi feito através do cálculo analítico do deslocamento quadrático médio (MSD) de um sistema unidimensional de N partículas não--interagentes através da solução da equação de difusão. No Capítulo 3, introduzimos o método de Dinâmica Molecular (DM), amplamente utilizado em simulações computacionais de sistemas de N partículas clássicas. Apresentamos dois métodos de integração numérica das equações de movimento: o algoritmo de Verlet e o algoritmo leapfrog. Abordamos brevemente o método de Dinâmica Molecular de Langevin (DML), que inclui um termo de flutuações térmicas (força estocástica), devido às colisões das moléculas do fluido com as partículas do sistema. Finalmente, apresentamos uma aproximação do método de DML chamada Dinâmica Browniana (DB). No Capítulo 4, estudamos as propriedades difusivas, através da análise do deslocamento quadrático médio, de um sistema de partículas clássicas carregadas sujeitas à ação de um potencial de confinamento unidimensional, analisando a transição do regime de difusão em linha (SFD) para o regime de difusão bidimensional (2D). Vimos como ocorre essa transição em função dos parâmetros que regulam o potencial de confinamento. Discutimos a validade dos resultados numéricos obtidos em relação a resultados analíticos teóricos encontrados na literatura. Finalmente, no Capítulo 5, apresentamos um resumo dos resultados obtidos, bem como discutimos perspectivas e sugestões para futuros trabalhos.

Os processos de conversão de energia tendem a considerar cada vez mais restrições econômicas e ambientais, tornando-se necessário o entendimento da interação entre combustão e turbulência. Este trabalho tem como objetivo o desenvolvimento de soluções analíticas para a fração de mistura de uma chama difusiva, sob forma de um jato turbulento axissimétrico. Foi desenvolvida, também, uma metodologia analíticonumérica para a determinação das frações mássicas dos componentes, considerando uma reação de combustão de dois passos. Os resultados foram comparados com dados experimentais encontrados na literatura para uma chama de hidrogênio H2=N2 (50/50% em volume). De modo geral, os resultados obtidos foram satisfatórios frente aos dados experimentais, sendo a principal limitação o fato das expressões analíticas obtidas não serem capazes de representar o jato próximo à saída do bocal, sendo válidas a partir de, aproximadamente, x=d > 10, onde x é a coordenada ao longo do comprimento do jato. A principal vantagem do método empregado neste trabalho é a diminuição da complexidade do sistema de equações a ser resolvido numericamente. / The energy conversion processes tend to consider even more economical and environmental constraints, making it necessary to understand the interaction between combustion and turbulence. This study aims at the development of analytical solutions for the mixture fraction of a diffusive flame in the form of an axisymmetric turbulent jet. It was also considered an analytical-numerical approach for the determination of the mass fractions of the compounds, for a two-step reaction. The results were compared with data found in literature for a hydrogen flame H2=N2 (50/50 % by volume). Overall, the results were satisfactory when compared with the experimental data, however the principal limitation was the fact that the analytical expressions were not able to represent the jet near the nozzle exit, being the solution valid from, approximately, x=d > 10, where x is the coordinate along the jet length. The main advantage of the method employed in this work is the decrease in the complexity of the equations system to be solved numerically.

abstract: Single cell analysis has become increasingly important in understanding disease onset, progression, treatment and prognosis, especially when applied to cancer where cellular responses are highly heterogeneous. Through the advent of single cell computerized tomography (Cell-CT), researchers and clinicians now have the ability to obtain high resolution three-dimensional (3D) reconstructions of single cells. Yet to date, no live-cell compatible version of the technology exists. In this thesis, a microfluidic chip with the ability to rotate live single cells in hydrodynamic microvortices about an axis parallel to the optical focal plane has been demonstrated. The chip utilizes a novel 3D microchamber design arranged beneath a main channel creating flow detachment into the chamber, producing recirculating flow conditions. Single cells are flowed through the main channel, held in the center of the microvortex by an optical trap, and rotated by the forces induced by the recirculating fluid flow. Computational fluid dynamics (CFD) was employed to optimize the geometry of the microchamber. Two methods for the fabrication of the 3D microchamber were devised: anisotropic etching of silicon and backside diffuser photolithography (BDPL). First, the optimization of the silicon etching conditions was demonstrated through design of experiment (DOE). In addition, a non-conventional method of soft-lithography was demonstrated which incorporates the use of two positive molds, one of the main channel and the other of the microchambers, compressed together during replication to produce a single ultra-thin (<200 µm) negative used for device assembly. Second, methods for using thick negative photoresists such as SU-8 with BDPL have been developed which include a new simple and effective method for promoting the adhesion of SU-8 to glass. An assembly method that bonds two individual ultra-thin (<100 µm) replications of the channel and the microfeatures has also been demonstrated. Finally, a pressure driven pumping system with nanoliter per minute flow rate regulation, sub-second response times, and < 3% flow variability has been designed and characterized. The fabrication and assembly of this device is inexpensive and utilizes simple variants of conventional microfluidic fabrication techniques, making it easily accessible to the single cell analysis community. / Dissertation/Thesis / M.S. Bioengineering 2012

Os processos de conversão de energia tendem a considerar cada vez mais restrições econômicas e ambientais, tornando-se necessário o entendimento da interação entre combustão e turbulência. Este trabalho tem como objetivo o desenvolvimento de soluções analíticas para a fração de mistura de uma chama difusiva, sob forma de um jato turbulento axissimétrico. Foi desenvolvida, também, uma metodologia analíticonumérica para a determinação das frações mássicas dos componentes, considerando uma reação de combustão de dois passos. Os resultados foram comparados com dados experimentais encontrados na literatura para uma chama de hidrogênio H2=N2 (50/50% em volume). De modo geral, os resultados obtidos foram satisfatórios frente aos dados experimentais, sendo a principal limitação o fato das expressões analíticas obtidas não serem capazes de representar o jato próximo à saída do bocal, sendo válidas a partir de, aproximadamente, x=d > 10, onde x é a coordenada ao longo do comprimento do jato. A principal vantagem do método empregado neste trabalho é a diminuição da complexidade do sistema de equações a ser resolvido numericamente. / The energy conversion processes tend to consider even more economical and environmental constraints, making it necessary to understand the interaction between combustion and turbulence. This study aims at the development of analytical solutions for the mixture fraction of a diffusive flame in the form of an axisymmetric turbulent jet. It was also considered an analytical-numerical approach for the determination of the mass fractions of the compounds, for a two-step reaction. The results were compared with data found in literature for a hydrogen flame H2=N2 (50/50 % by volume). Overall, the results were satisfactory when compared with the experimental data, however the principal limitation was the fact that the analytical expressions were not able to represent the jet near the nozzle exit, being the solution valid from, approximately, x=d > 10, where x is the coordinate along the jet length. The main advantage of the method employed in this work is the decrease in the complexity of the equations system to be solved numerically.

Dissertação(mestrado) - Universidade Federal do Rio Grande, Programa de Pós-Graduação em Oceanografia Física, Química e Geológica, Instituto de Oceanografia, 2005. / Submitted by Cristiane Silva (cristiane_gomides@hotmail.com) on 2013-01-28T12:25:06Z No. of bitstreams: 1 2005_Carlos_de_Andrade.pdf: 1453728 bytes, checksum: 61ca4996bcaf13cd39bc0418f7b5608b (MD5) / Approved for entry into archive by Bruna Vieira(bruninha_vieira@ibest.com.br) on 2013-06-13T18:51:07Z (GMT) No. of bitstreams: 1 2005_Carlos_de_Andrade.pdf: 1453728 bytes, checksum: 61ca4996bcaf13cd39bc0418f7b5608b (MD5) / Made available in DSpace on 2013-06-13T18:51:07Z (GMT). No. of bitstreams: 1 2005_Carlos_de_Andrade.pdf: 1453728 bytes, checksum: 61ca4996bcaf13cd39bc0418f7b5608b (MD5) Previous issue date: 2005 / A cidade de Rio Grande, localizada às margens do estuário da Lagoa dos Patos, possui uma intensa atividade portuária e industrial, fatores que promoveram nas últimas décadas, alterações significativas nas paisagens e na degradação dos recursos hídricos, incluindo a contaminação por nutrientes e por metais. Por ser um estuário semi-fechado, possui uma alta taxa hidrodinâmica, condicionada principalmente pela força e direção dos ventos. Os ciclos biogeoquímicos naturais dos metais na coluna dágua, podem ser alterados devido ao lançamento de metais oriundos das atividades humanas. Alterações na fração dos metais podem ocasionar uma maior biodisponibilidade destes elementos para os organismos. A determinação das espécies de metais biodisponíveis (lábil) por técnicas instrumentais ou analíticas, possuem implicações quanto à obtenção da concentração representativa do meio, por estar sujeita a erros de amostragem e preparo das amostras. Com o desenvolvimento da técnica de gradiente difusivo de membranas (DGT), obtem-se a concentração da fração lábil in situ em distintos ambientes sob diversas condições de pH, temperatura e salinidade. O presente trabalho tem como objetivo avaliar e aplicar a técnica DGT, para o monitoramento e detecção da concentração de elementos traço em distintos locais da área estuarina da Lagoa dos Patos. Para avaliar a aplicabilidade da técnica para o estuário, foram considerados dois períodos de exposição do sistema DGT em três locais: um com pouca influência (Ilha dos Marinheiros - IM) e dois com maior influencia dos despejos industriais e urbanos (Capitania dos Portos - CP e Museu Oceanográfico - MO). Para o primeiro período de exposição (2, 6 e 10 dias) das unidades de DGT foram analisados Cd, Co, Cu, Mn, Ni, Pb e Zn em DGT e água nos locais IM e CP. Para o segundo período de exposição (2, 4, 6 e 8 horas) DGT e água foram analisados para Cd, Cu, Pb e Zn no local MO em duas amostragens, uma com salinidade intermediária (MO1) e a outra com salinidade alta (MO2). Para ambos períodos de exposições, amostras de água analisadas para a fração lábil de metais com resina Chelex 100, demonstraram concentrações distintas em comparação ao DGT, evidenciando a diferença entre os dois métodos. Os resultados no DGT para o primeiro período de exposição (IM e CP) mostraram um decréscimo nas concentrações de todos os elementos, com o aumento do tempo de exposição. Isto provavelmente tenha ocorrido devido à baixa concentração de metais lábeis na água e/ou possível presença de biofilm nas unidades de DGT. Não foram reveladas concentrações significativas de Cu, Pb, Ni e Zn nos locais IM e CP. Para o segundo período de exposição, as concentrações de metais foram mais elevadas para Cd, Cu e Pb em alta salinidade (MO2), além de ter indicado aporte para este elementos no meio, quando comparado com outros estuários. Em conseqüência das variabilidades do estuário, conclui-se que uma resposta mais representativa para o sistema DGT, seria mantê-lo num período fixo de 8 a 48 horas em exposição no ambiente. / Rio Grande is a city located in the margin of the Patos Lagoon estuary and its maritime harbour and industries are very developed. During the last decades, these activities were responsible for many changes of the landscape and degradation of water resources, including contamination by nutrients and metals. This semi-closed estuary has a high hydrodynamic rate, which is determined manly by the wind direction and strength. The natural biochemical cycles of metals can be modified by discharge of metals originated by human activities. Changes in the metal fractions can lead to a higher bioavailability of these elements to the organisms. The determination of bioavailable (labile) metals by instrumental or analytical techniques can have implications on the representative environmental concentration, since errors during sample collection and preparation can occur. The development of the diffusive gradient thin-films (DGT) technique made possible the determination of labile metals in situ in distinct environments with different conditions of pH, temperature and salinity. The main objective of the present study is to apply and to evaluate the DGT technique, for the monitoring and detection of trace elements concentrations in different areas of the Patos Lagoon estuary. To evaluate the applicability of this technique to the estuary, two deployment periods of the DGT units were considered in three areas: one with low antropogenic influence (Ilha dos Marinheiros – IM) and two in high urban and industrial discharge areas (Capitania dos Portos – CP – and Museu Oceanográfico – MO). For the first period of the DGT deployment (2, 6 and 10 days) DGT and water samples were analyzed for Cd, Co, Cu, Mn, Ni, Pb and Zn at the IM and CP sites. For the second deployment period (2, 4, 6 and 8 hours), Cd, Cu, Pb e Zn were analyzed for DGT and water samples were collected at the MO point, during two different conditions of salinity, one with intermediate values (MO1) and the other with high salinity (MO2). For both deployment periods, water samples analyzed for labile fraction with Chelex-100 resin showed distinct concentrations, when compared with the DGT, indicating differences between the two methods. The DGT results showed for the first deployment period (IM and CP) a decrease with time in the concentration for all elements. Probably this had occurred due to variations on the labile form of the metals and/or the presence of biofilm. No significant differences were found in the concentration of Cu, Pb, Ni and Zn between IM and CP sites. For the second deployment period, trace metal concentrations showed higher values for Cd, Cu and Pb during high salinity (MO2) condition, as well as indicating input of these elements in the surroundings when compared with other estuaries. As a consequence of variability’s in the estuary, it can be concluded that for a more representative result of the DGT units, these should be deployed during 8 to 48h on a fixed period in the environment.

Stochastic differential equations are becoming a popular tool for modeling the transport and acceleration of cosmic rays in the heliosphere. In diffusive shock acceleration, cosmic rays diffuse across a region of discontinuity where the up- stream diffusion coefficient abruptly changes to the downstream value. Because the method of stochastic integration has not yet been developed to handle these types of discontinuities, I utilize methods and ideas from probability theory to develop a conceptual framework for the treatment of such discontinuities. Using this framework, I then produce some simple numerical algorithms that allow one to incorporate and simulate a variety of discontinuities (or boundary conditions) using stochastic integration. These algorithms were then modified to create a new algorithm which incorporates the discontinuous change in diffusion coefficient found in shock acceleration (known as Skew Brownian Motion). The originality of this algorithm lies in the fact that it is the first of its kind to be statistically exact, so that one obtains accuracy without the use of approximations (other than the machine precision error). I then apply this algorithm to model the problem of diffusive shock acceleration, modifying it to incorporate the additional effect of the discontinuous flow speed profile found at the shock. A steady-state solution is obtained that accurately simulates this phenomenon. This result represents a significant improvement over previous approximation algorithms, and will be useful for the simulation of discontinuous diffusion processes in other fields, such as biology and finance.

Urban runoff is a non-point pollution source deteriorating water quality of natural watersystems. The composition of urban runoff vary depending on land use, seasonal changes anddifferent surfaces that come into contact with the water. Urban runoff often contain metals andAl, Cd, Cr, Cu, Fe, Ni, Pb and Zn are of particular concern for the environment due to theirpotential toxicity. Metals in runoff can be present in different phases, associated with particles,colloids of different sizes or dissolved in the free phase. The different phases vary in size butalso overlap each other. Information about metal phases and species in runoff is essential tounderstanding metal transport and design runoff treatment systems.Membrane filtration followed by ultrafiltration is an established technique to distinguish theparticulate, colloidal and truly dissolved fractions. However, the “truly dissolved” fraction mayconstitute of the free phase, colloidal phase or both of them since the technique onlydiscriminates by size. Diffusive gradients in thin films (DGT) is a relatively new technique thatmeasures the labile fraction, sometimes referred to as the most bioavailable fraction. The labilefraction includes free metal ions and small complexes available to diffuse through a diffusivelayer under a reasonable period of time. Kinetically inert species are discriminated.The scope of this thesis was to investigate metal fractionation in snowmelt runoff from differenturban surfaces using two techniques, ultrafiltration and DGT. An additional aim was to studythe speciation described by the two techniques in the different types of runoff. Two types ofrunoff were sampled to conduct measurements on. Runoff from well-defined catchments (anindustrial area and a parking lot) and roof runoff from two roofing materials (zinc and coppersheet). In total, four runoff samples were membrane filtrated (pore size 0.45 μm) followed byeither ultrafiltration (delimiting 3 kNMWL) or DGT measurements in the laboratory. Analysisof metals was conducted in all steps and pH, electric conductivity, total suspended solids andtotal organic carbon was measured in the untreated samples.The results show that metal concentrations were generally higher in the catchment runoffcompared to the roof runoff with few exceptions, Cu and Pb from copper roof and Zn from zincroof. Regarding fractionation, the two types of runoff showed similarities when it came tometals mainly bound to particles. The metals that were abundant in several phases showeddifferent fractionations between the catchment runoff and the roof runoff. The metals releasedin roof runoff was to a higher extent found as free ions compared with the catchment runoff. Adiscussion was held about the different metal fractions and treatment possibilities. Comparingthe two techniques, the DGT measurements could be used to further interpret the results fromthe ultrafiltration regarding the colloidal and free phase. / Dagvatten är en diffus föroreningskälla som försämrar vattenkvalitén hos naturliga vattendrag.Samansättningen av föroreningar i dagvatten kan variera beroende på markanvändning,årstidsvariationer och de olika ytor som dagvattnet kommer i kontakt med. Dagvatten innehållerofta metaller och Al, Cd, Cr, Cu, Fe, Ni, Pb och Zn kan vara toxiska för miljön i högakoncentrationer. Metaller i dagvatten kan förekomma i olika faser beroende på om de är bundnamed partiklar, kolloider av olika storlek eller om de är i löst fas. De olika faserna varierar istorlek men överlappar även varandra något. Kunskap om de olika faserna är viktigt förförståelsen om metallernas transportmekanismer och för att kunna designa eller förbättrareningssystem.Membranfiltrering följt av ultrafiltrering är en etablerad teknik för att särskilja partikulärtmaterial, kolloider och den sanna lösta fraktionen. Dock så kan den ”sanna lösta” fraktioneninnehålla antingen den kolloidala fasen, lösta fasen eller båda två eftersom tekniken baseras påstorleksfördelning. DGT (på engelska diffusive gradients in thin films) är en relativt ny tekniksom mäter den labila fraktionen som ibland benämns som den mest biotillgängliga fraktionen.Den labila fraktionen inkluderar fria metalljoner men även små komplex som kan diffunderagenom en diffusionsgel under en rimlig tidsperiod. Species som är kinetisk inerta kommer intemätas.Syftet med detta arbete var att undersöka metallfraktionering i snösmälts-avrinning från olikaurbana ytor genom att använda två tekniker, ultrafiltrering och DGT. Ett delmål var även attgranska de species som beskrevs av de två teknikerna i de olika typerna av dagvatten. Två olikaslags dagvatten samlades in och undersöktes. Dagvatten från väldefinierade avrinningsområden(ett industriområde och en parkeringsplats) och takavrinning från två takmaterial (zink- ochkopparplåtar). Totalt fyra dagvattenprover genomgick membranfiltrering (porstorlek 0,45 μm)följt av antingen ultrafiltrering (avgränsning 3 kNMWL) eller DGT mätningar i laboratoriet.Metallanalyser genomfördes i alla steg och pH, konduktivitet, suspenderade partiklar ochorganiskt kol mättes på det obehandlade proverna.Resultaten visade att de uppmätta metallkoncentrationerna var generellt högre i takavrinningenjämfört med dagvattnet från de hela avrinningsområdena. Dock med några undantag, Cu ochPb från koppartak och Zn från zinktak. När det kom till fraktionering fanns det likheter mellanavrinning från hela områden och från taken beträffande de metaller som till största del varbundna till partiklar. Däremot var det skillnad mellan de olika avrinningstyperna gällandefraktionering av metallerna som förekom i flera av faserna. I takavrinningen fanns det i störreutsträckning metaller som fria joner jämfört med avrinningsområdena. En slutsats var att DGTmätningarna kunde användas till att tolka resultaten från ultrafiltreringen när det gälldekolloidala och fria faserna.

Cette thèse s'intéresse à la migration cellulaire d'une population composée de deux espèces qui interagissent par le biais de signaux chimiques. Ces signaux chimiques auxquels sont soumis les deux espèces sont de nature différente. Ils sont soit intérieur (produit par les deux espèces) ou bien extérieur (apporté par le milieu et consommé par les deux espèces). On observe le phénomène de synchronisation et de désynchronisation lors de la migration d'une population composée de deux espèces différentes d'E.Coli. Séparément, les bactéries rouges d'E.Coli se déplacent deux fois plus vite que les bactéries vertes. Cependant dans le cas d'une population mixte composée de rouges et de vertes, les bactéries rouges et vertes se déplacent ensemble ou séparément en fonction de la proportion de la bactérie la plus rapide rouge dans la population.Cette observation expérimentale est interprétée par un modèle macroscopique parabolique de chimiotactisme à deux espèces pour lequel l'existence et la non-existence des ondes de concentration sont prouvées. Ce modèle macroscopique parabolique à deux espèces est construit à partir des modèles microscopiques qui traduisent le mouvement individuel des cellules.Ce phénomène de synchronisation et de désynchronisation est aussi présent dans la dynamique des masses de dirac des deux espèces après l'explosion des solutions classiques dans un modèle d'agrégation à deux espèces avec une seule substance chimique.Nous proposons aussi dans cette thèse une méthode pour obtenir des schémas numériques préservant à la fois l'équilibre et l'asymptotique. Cette méthode est testée aux modèles cinétiques de chimiotactisme et de transfert radiatif. / This thesis is concerned about cellular motion of a population composed of two species in interaction through chemical cues. The chemical cues to which the two species are subject are of different kind.They can be internal (produced by the two species) or external (present in the meduim and consommed by the two species). Synchronising and non-synchronising effects are observed during the migration of the population formed by two different strains of E.Coli.Although separately, red bacteria E.Coli travel twice as fast as green bacteria E.Coli, put together, they travel or split depending on the percentage of the faster bacteria in the population. This experimental result is explained by a two-species parabolic macroscopic chemotaxis model for which the existence and non-existence of traveling pulses are showed. The parabolic macroscopic model is derived from microscopic models which describe the individual motion of cells. The synchronising and non-synchronising effect is also encountered in dynamics of the two-species dirac masses after blow-up of classical solutions in a two-species model for aggregation. A method to design both well-balanced and asymptotic preserving schemes is proposed. This method is tested to chemotaxis and radiative transport kinetic models.

Recent years have seen remarkable progress in our understanding of physical aging in nondisordered systems with slow, i.e. glassy-like dynamics. In many systems a single dynamical length L(t), that grows as a power-law of time t or, in much more complicated cases, as a logarithmic function of t, governs the dynamics out of equilibrium. In the aging or dynamical scaling regime, these systems are best characterized by two-times quantities, like dynamical correlation and response functions, that transform in a specific way under a dynamical scale transformation. The resulting dynamical scaling functions and the associated non-equilibrium exponents are often found to be universal and to depend only on some global features of the system under investigation. We discuss three different types of systems with simple and complex aging properties, namely reaction diffusion systems with a power growth law, driven diffusive systems with a logarithmic growth law, and a non-equilibrium polymer network that is supposed to capture important properties of the cytoskeleton of living cells. For the reaction diffusion systems, our study focuses on systems with reversible reaction diffusion and we study two-times functions in systems with power law growth. For the driven diffusive systems, we focus on the ABC model and a related domain model and measure two- times quantities in systems undergoing logarithmic growth. For the polymer network model, we explain in some detail its relationship with the cytoskeleton, an organelle that is responsible for the shape and locomotion of cells. Our study of this system sheds new light on the non- equilibrium relaxation properties of the cytoskeleton by investigating through a power law growth of a coarse grained length in our system. / Ph. D.

京都大学 / 0048 / 新制・課程博士 / 博士(工学) / 甲第20679号 / 工博第4376号 / 新制||工||1680(附属図書館) / 京都大学大学院工学研究科社会基盤工学専攻 / (主査)教授 寶 馨, 教授 立川 康人, 准教授 佐山 敬洋 / 学位規則第4条第1項該当 / Doctor of Philosophy (Engineering) / Kyoto University / DFAM