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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Análise quantitativa da imagem ultra-sonográfica de testículos de bovinos jovens da raça Nelore /

Cardilli, Diogo José. January 2008 (has links)
Resumo: O exame ultra-sonográfico dos testículos é um método não invasivo e rápido, que aliado aos dados de exame clínico, pode conduzir ao diagnóstico precoce de desordens desse órgão, no entanto, a análise da imagem é subjetiva, pois depende do examinador. Sendo assim, instituir valores aos diferentes tons da escala de cinza possibilita a determinação quantitativa do padrão de normalidade para o parênquima testicular. O objetivo do trabalho é avaliar o aspecto ultra-sonográfico e analisar quantitativamente as imagens dos testículos de bovinos jovens da raça Nelore, e estabelecer parâmetros e padrões fisiológicos normais. Foram realizados exames ultrasonográficos dos testículos de 130 bovinos hígidos da raça Nelore, sendo 19 animais da fazenda 1 e 111 animais da fazenda 2. Os animais da fazenda 1 foram avaliados em cinco momentos: aos nove, 11, 13, 15 e 18 meses; ao passo que os da segunda foram avaliados aos nove, 13 e 15 meses. Com o auxílio do software "Echo Image Viewer" (EIV), foram selecionadas regiões de interesse (RI) em cada plano de varredura, assim denominadas: frontal direita (RIFD); frontal esquerda (RIFE); transversal direita (RITD); transversal esquerda (RITE). Automaticamente o software EIV calculou a média da escala de cinzas, a qual variou de 0 a 100%, sendo 0% preto (menor ecogenicidade) e 100% branco (maior ecogenicidade). O teste de Tukey foi empregado para comparar as médias das RI dentro e entre cada momento (p<0,05) utilizando-se o programa estatístico SAS (2001). A ecogenicidade testicular aumentou com o passar da idade nos animais de ambas as fazendas. Touros púberes apresentaram maior ecogenicidade testicular que os impúberes com a mesma idade. A cauda do epidídimo mostrou-se menos ecogênica que o parênquima testicular. A espessura do mediastino testicular, o volume testicular e o perímetro escrotal aumentaram com o passar da idade...(Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The ultrasononographic examination of testicles is a noninvasive and rapid method that, allied to clinical examination, can lead to an early diagnostic of testicles disorders, however, the image's analysis is subjective, because it depends on the professional. To institute values to different tones of gray scale aloud, then, a quantitative determination of normality's standard to testicular parenchyma. The aim of that study is to evaluate the ultrasonographic's aspect and analyse in a quantitative way the images of young Nelore bovine's testicles, and to establish normal and physiological parameters and standards. Ultrasonographic examinations of 130 healthy Nelore bovines were realized, 19 in farm 1 and 111 in farm 2. The animals of farm 1 were evaluated in five moments: at nine, 11, 13, 15 and 18 months; and the animals of farm 2 were evaluated at nine, 13 and 15 months. With the support of the software "Echo Image Viewer" (EIV), interesting areas (IA) were selected in each plane, forward denominated: right frontal (IArf), left frontal (IAlf), right transversal (IArt), left transversal (IAlt). Automatically the EIV software calculated the gray scale average, on a scale of 0 (black, the less echogenicity) to 100% (white, the most echogenicity). The Tukey test were used to compare the IA's averages in and between each moments (p<0,05) using the SAS statistic program (2001). The testicular echogenicity increased along the ages on both farm's animals. Bulls at puberty showed bigger testicular echogenicity than bulls not at puberty with the same age. The tail of epididymis showed less echogenicity than testicular's parenchyma. The thickness of mediastinum testis, testicular volume and scrotal circumference increased along the ages and positive correlations were found between testicular echogenicity, testicular volume and scrotal circunference. / Orientador: Gilson Helio Toniollo / Coorientador: Júlio Carlos Canola / Coorientadora: Maria Eugênia Zerlotti Mercadante / Banca: Francisco Guilherme Leite / Banca: Sony Dimas Bicudo / Mestre
2

Acoustic Imaging of Bruises

Prabhakara, Sandeep 22 May 2006 (has links)
Ultrasound is a valuable tool to monitor wound healing. In this report, ultrasound is used to determine the features in the B-scans that correspond to a bruise. High frequency ultrasound scans show clear and distinct features that correspond to a laceration or a late stage pressure ulcer. This is because of the extensive damage and the rupture of the epidermis in both the cases. This study assumes significance because it is an effort to find such artifacts in the ultrasound scans of bruises caused by blunt forces where the epidermis remains intact. In this study, the structure of the skin was visualized using a 20 MHz ultrasound scanner. Skin thickness and echogenicity changes may result due to blood extravasations or edema. The thickness and the echogenicity values are plotted against time to determine the trend in the variation of these parameters. We see an intraday and a daily fluctuation of skin thickness and echogenicity albeit with no distinct trend on a day to day basis or between subjects. The results also give us a good estimation of the variation observable in these parameters in the event of an injury. A snapshot analysis is also performed, which describes qualitatively the structural changes in the B-scan of the bruise site compared to the control site. There are six different types of qualitative changes which can appear in the B-scan of a bruised site compared to the control. In the event of an injury, usually, more than one of these changes is manifested in the scan of a bruise. Skin thickness and echogenicity vary considerably due to a number of physiological factors which can seldom be controlled. Therefore, these parameters can give conclusive evidence of a bruise only if the change between a bruised region and a control region is much greater than the daily, normal variations. Snapshot analysis can help detect a bruise or a deep tissue injury. Further work involves the application of pattern recognition or face recognition algorithms to automate the detection.
3

Carotid artery disease : plaque features and vulnerability

Jashari, Fisnik January 2015 (has links)
Background: Atherosclerosis is an important cause of stroke. Ultrasound offers the convenience of real-time and detailed assessment of carotid plaque features as well as arterial wall thickening and composition. Evaluation of these features is important for determining patients’ risk of suffering vascular events and also contributes to selecting the best treatment strategy. Methods: Using ultrasound data analysis we have determined plaque features in the bifurcation and internal carotid artery (ICA), including: surface plaque irregularities, calcification, echogenicity (grey scale median-GSM) and other textural plaque features (Juxtaluminal black area, entropy, coarseness). In addition, intima media thickens (IMT) and its grey scale median (IM-GSM) was measured in common carotid artery (CCA). Using Cone Beam CT (CBCT) we have quantified calcification volume of the carotid plaques extracted after carotid endarterectomy procedure. For the meta-analysis we have used comprehensive meta-analysis software version 3. Study I: We have included 39 patients and we compared carotid plaque features of the contralateral arteries with those located ipsilateral to symptomatic side and arteries of asymptomatic patients. Study II: The accuracy of US to detect atherosclerosis calcification was assessed against CBCT in 88 patients. Study III: Based on the previous vascular events in coronary, carotid and lower extremity arterial system, 87 patients were divided into three groups: asymptomatic, symptoms in one vascular system and symptoms in more that one vascular system. IMT, IM-GSM and plaque features were compared between groups. Study IV: We have meta-analyzed ten cohort prospective studies evaluating carotid plaque echogenicity for cerebrovascular symptoms prediction. Results: Study I. Plaques of the contralateral to symptomatic arteries had similar features to those in symptomatic and more vulnerable than asymptomatic arteries. Study II. Carotid ultrasound was accurate in detecting calcification volumes of ≥8mm3 with very high sensitivity but it was less accurate in detecting lower calcification volumes (&lt;8mm3). Carotid calcification was not different between symptomatic and asymptomatic patients. Study III. Echogenicity of the intima-media complex (IM-GSM), but not its thickness (IMT), was significantly decreased with increasing number of arterial systems affected by atherosclerosis. IM-GSM was lower in patients with prior myocardial infarction and stroke. Study IV. Carotid plaque echogenicity evaluated by US could predict future cerebrovascular events in patients with asymptomatic, relative risk RR 2.72 (95% CI, 1.86 to 3.96), and recurrent symptoms in symptomatic patients, RR 2.97 (95% CI, 1.85-4.78). Conclusion: Plaques located in the contralateral to symptomatic arteries have similar features as symptomatic side and more vulnerable than asymptomatic arteries. Carotid ultrasound could accurately detect larger but not smaller carotid plaque calcification volumes (&lt;8 mm3). Low IM- GSM could identify patients with multi-system atherosclerosis disease, suggesting a better marker for determining systemic atherosclerosis disease burden compared to conventional IMT. Finally, carotid plaque echogenicity predicts future cerebrovascular events in patients with symptomatic and asymptomatic carotid stenosis.
4

Clinical Significance of the Echogenicity in Prostatic Ultrasound Findings in the Detection of Prostatic Carcinoma

Manseck, Andreas, Guhr, K., Hakenberg, Oliver, Rossa, Karsten, Wirth, Manfred P. 26 February 2014 (has links) (PDF)
Background: Transrectal ultrasound is commonly performed in the clinical evaluation of the prostate. Ultrasound-guided randomized sextant biopsy became the standard procedure for the diagnosis of carcinoma of the prostate (CaP). A guided biopsy of sonographically irregular lesions of the prostate is not performed in randomized biopsies. An almost generally accepted opinion is that hypoechoic lesions are suspicious for the presence of CaP. However, the role of prostatic lesions with an echogenicity other than iso- or hypoechoic, e.g. hyperechoic or irregular lesions in relation to CaP is not clear. The intention of the present prospective study was to clarify the role of different prostatic ultrasound findings with a new-generation ultrasound probe in regard to their relevance concerning the presence of cancer. Material and Methods: 265 patients who were referred for prostatic evaluation because of an elevated PSA serum level or a positive digital rectal examination were enrolled in a prospective study. All patients had a systematic ultrasound-guided sextant biopsy of the prostate and a 4-core biopsy of the transition zone. All biopsy cores taken were guided by transrectal ultrasound. In case of a sonographically suspicious lesion, biopsy was always directed into this area. The predominant ultrasound appearance was separately recorded for each core. Results: Carcinoma of the prostate was detected in 87 (32.8%) of the 265 patients. Biopsy cores with isoechoic ultrasound findings revealed CaP in 7.6%. The data for hypoechoic, hyperechoic, mixed-echoic and anechoic lesions were 34.5, 26.9, 21.1 and 0%, respectively. Hypoechoic ultrasound findings were less frequently found in the transition zone of the prostate, but the rate of CaP detection was the same as in the peripheral zone of the prostate. Conclusions:The transrectal ultrasound pattern of the prostate yields important information about the presence of carcinoma of the prostate. Especially hypoechoic lesions indicate the presence of CaP in a significant proportion of cases. However, hyperechoic lesions and lesions of mixed or irregular echogenicity were found to contain cancer in significant numbers as well, and should therefore be considered to be suspicious for cancer when performing transrectal ultrasound of the prostate. Directed biopsy of irregular ultrasound patterns in the prostate seems therefore to be recommendable. / Hintergrund: Der transrektale Ultraschall ist die häufigste bildgebende Untersuchung zur klinischen Beurteilung der Prostata. Zur Diagnostik des Prostatakarzinoms (PCa) hat sich die ultraschallgesteuerte Sextanten-Biopsie als Standardverfahren etabliert. Eine gezielte Biopsie irregulärer Ultraschallbezirke ist hier nicht vorgesehen. Es ist jedoch bekannt, daß sonographisch echoarm erscheinende Areale suspekt für die Präsenz eines PCa sind. Die Wertigkeit nicht einheitlicher oder echoreicher Ultraschallmuster ist jedoch bisher nicht zweifelsfrei geklärt. Ziel der vorliegenden Arbeit war es, mit einem Ultraschallgerät der neuesten Generation die Bedeutung der verschiedenen Ultraschallmuster bezüglich des Vorhandenseins von Prostatakarzinomen zu klären. Material und Methoden: 265 Patienten mit erhöhten PSA-Serumwerten oder suspekten Tastbefunden der Prostata wurden in die prospektive Untersuchung eingeschlossen. Bei allen Patienten wurden systematische, ultraschallgesteuerte Prostatabiopsien, wie in der Sextantenbiopsie vorgesehen, und 4 Zylinder aus der Transitionalzone entnommen. Bei der Biopsie wurde jedoch gezielt die Punktion in Bereichen von – falls vorhanden – irregulärem Ultraschallmuster vorgenommen und das entsprechende Ultraschallbild dokumentiert. Ergebnisse: Bei 87 der 265 Patienten (32,8%) wurden Prostatakarzinome nachgewiesen. Biopsiezylinder aus isodensen Bereichen wiesen in 7,6% ein Prostatakarzinom auf. Die Karzinomhäufigkeit bei Biopsie von echoarmen und echoreichen Arealen sowie von Arealen mit unterschiedlichen Echomustern und von zystischen Arealen wurde mit 34,5, 26,9, 21,1 bzw. 0% ermittelt. Echoarme Befunde wurden seltener in der Transitionalzone nachgewiesen, waren jedoch dort in etwa gleicher Häufigkeit mit einem Karzinom verbunden wie in der peripheren Zone. Schlußfolgerungen: Das transrektale Ultraschallmuster in der Prostata liefert wichtige Hinweise auf das Vorhandensein eines Prostatakarzinoms. Insbesondere echoarme Läsionen deuten auf ein PCa hin. Echoreiche Läsionen und solche mit unterschiedlichen Echomustern enthielten jedoch Karzinome in so bedeutender Anzahl, daß diese Läsionen ebenfalls als karzinomverdächtig eingestuft werden müssen und auch eine gezielte Biopsie dieser Areale im Rahmen der Sextantenbiopsie empfehlenswert erscheint. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
5

Análise quantitativa da imagem ultra-sonográfica de testículos de bovinos jovens da raça Nelore

Cardilli, Diogo José [UNESP] 27 February 2008 (has links) (PDF)
Made available in DSpace on 2014-06-11T19:23:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-27Bitstream added on 2014-06-13T19:30:11Z : No. of bitstreams: 1 cardilli_dj_me_jabo.pdf: 1854352 bytes, checksum: c87bee660fac9140ecfc34f52d06f40d (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / O exame ultra-sonográfico dos testículos é um método não invasivo e rápido, que aliado aos dados de exame clínico, pode conduzir ao diagnóstico precoce de desordens desse órgão, no entanto, a análise da imagem é subjetiva, pois depende do examinador. Sendo assim, instituir valores aos diferentes tons da escala de cinza possibilita a determinação quantitativa do padrão de normalidade para o parênquima testicular. O objetivo do trabalho é avaliar o aspecto ultra-sonográfico e analisar quantitativamente as imagens dos testículos de bovinos jovens da raça Nelore, e estabelecer parâmetros e padrões fisiológicos normais. Foram realizados exames ultrasonográficos dos testículos de 130 bovinos hígidos da raça Nelore, sendo 19 animais da fazenda 1 e 111 animais da fazenda 2. Os animais da fazenda 1 foram avaliados em cinco momentos: aos nove, 11, 13, 15 e 18 meses; ao passo que os da segunda foram avaliados aos nove, 13 e 15 meses. Com o auxílio do software “Echo Image Viewer” (EIV), foram selecionadas regiões de interesse (RI) em cada plano de varredura, assim denominadas: frontal direita (RIFD); frontal esquerda (RIFE); transversal direita (RITD); transversal esquerda (RITE). Automaticamente o software EIV calculou a média da escala de cinzas, a qual variou de 0 a 100%, sendo 0% preto (menor ecogenicidade) e 100% branco (maior ecogenicidade). O teste de Tukey foi empregado para comparar as médias das RI dentro e entre cada momento (p<0,05) utilizando-se o programa estatístico SAS (2001). A ecogenicidade testicular aumentou com o passar da idade nos animais de ambas as fazendas. Touros púberes apresentaram maior ecogenicidade testicular que os impúberes com a mesma idade. A cauda do epidídimo mostrou-se menos ecogênica que o parênquima testicular. A espessura do mediastino testicular, o volume testicular e o perímetro escrotal aumentaram com o passar da idade... / The ultrasononographic examination of testicles is a noninvasive and rapid method that, allied to clinical examination, can lead to an early diagnostic of testicles disorders, however, the image’s analysis is subjective, because it depends on the professional. To institute values to different tones of gray scale aloud, then, a quantitative determination of normality’s standard to testicular parenchyma. The aim of that study is to evaluate the ultrasonographic´s aspect and analyse in a quantitative way the images of young Nelore bovine’s testicles, and to establish normal and physiological parameters and standards. Ultrasonographic examinations of 130 healthy Nelore bovines were realized, 19 in farm 1 and 111 in farm 2. The animals of farm 1 were evaluated in five moments: at nine, 11, 13, 15 and 18 months; and the animals of farm 2 were evaluated at nine, 13 and 15 months. With the support of the software “Echo Image Viewer” (EIV), interesting areas (IA) were selected in each plane, forward denominated: right frontal (IArf), left frontal (IAlf), right transversal (IArt), left transversal (IAlt). Automatically the EIV software calculated the gray scale average, on a scale of 0 (black, the less echogenicity) to 100% (white, the most echogenicity). The Tukey test were used to compare the IA`s averages in and between each moments (p<0,05) using the SAS statistic program (2001). The testicular echogenicity increased along the ages on both farm’s animals. Bulls at puberty showed bigger testicular echogenicity than bulls not at puberty with the same age. The tail of epididymis showed less echogenicity than testicular`s parenchyma. The thickness of mediastinum testis, testicular volume and scrotal circumference increased along the ages and positive correlations were found between testicular echogenicity, testicular volume and scrotal circunference.
6

Relationship between loss of echogenicity and cavitation emissions from echogenic liposomes insonified by spectral Doppler ultrasound

Radhakrishnan, Kirthi January 2013 (has links)
No description available.
7

Estudio ecográfico (ecogenicidad y área) de los tendones flexores de la extremidad anterior del caballo Pura Raza Español

Martínez Martínez, Mª de los Llanos 25 April 2005 (has links)
La ecografía es una técnica ampliamente utilizada para evaluar las lesiones tendinosas en los caballos, hasta este momento no se ha realizado ningún estudio sobre la ecogenicidad y el área de los tendones flexores y ligamentos de la zona metacarpiana del Pura Raza Español (P.R.E). El objetivo de nuestro estudio es determinar el área y la ecogenicidad de los tendones flexores y ligamentos de la zona del metacarpo, y determinar si tiene algún efecto la edad, el sexo, la extremidad y la zona de corte a ecografiar sobre estos parámetros en el caballo PRE.De este trabajo podemos concluir que la edad y la zona del metacarpo donde se realiza el examen tienen un efecto tanto en la ecogenicidad como en el área. Mientras que la extremidad sólo influye en los valores del área. Sin embargo, no se encontró ninguna diferencia entre machos y hembras ni en la ecogenicidad ni en los valores del área. / The ultrasonographic assessment of tendon injuries can be based on several criteria. The purposes of this study were to establish normal values for CSA and ME of flexor tendons and ligaments of the metacarpal region of Andalusian horses; to determine the normal relation between the different tendons and ligaments; to determine the normal relation between the male and female for each tendon and ligament; to determine the normal relation between the left and right limbs for each tendon and ligament and to determine the normal relation between different age (young, adult and senile) for each tendon and ligament.In conclusion, this work suggests that the age and level have an effect on CSA and ME of the tendons and ligaments. The limb has also an effect on CSA of each tendon and ligament. Differences in CSA or ME of each tendon were not found between males and females.
8

Clinical Significance of the Echogenicity in Prostatic Ultrasound Findings in the Detection of Prostatic Carcinoma

Manseck, Andreas, Guhr, K., Hakenberg, Oliver, Rossa, Karsten, Wirth, Manfred P. January 2000 (has links)
Background: Transrectal ultrasound is commonly performed in the clinical evaluation of the prostate. Ultrasound-guided randomized sextant biopsy became the standard procedure for the diagnosis of carcinoma of the prostate (CaP). A guided biopsy of sonographically irregular lesions of the prostate is not performed in randomized biopsies. An almost generally accepted opinion is that hypoechoic lesions are suspicious for the presence of CaP. However, the role of prostatic lesions with an echogenicity other than iso- or hypoechoic, e.g. hyperechoic or irregular lesions in relation to CaP is not clear. The intention of the present prospective study was to clarify the role of different prostatic ultrasound findings with a new-generation ultrasound probe in regard to their relevance concerning the presence of cancer. Material and Methods: 265 patients who were referred for prostatic evaluation because of an elevated PSA serum level or a positive digital rectal examination were enrolled in a prospective study. All patients had a systematic ultrasound-guided sextant biopsy of the prostate and a 4-core biopsy of the transition zone. All biopsy cores taken were guided by transrectal ultrasound. In case of a sonographically suspicious lesion, biopsy was always directed into this area. The predominant ultrasound appearance was separately recorded for each core. Results: Carcinoma of the prostate was detected in 87 (32.8%) of the 265 patients. Biopsy cores with isoechoic ultrasound findings revealed CaP in 7.6%. The data for hypoechoic, hyperechoic, mixed-echoic and anechoic lesions were 34.5, 26.9, 21.1 and 0%, respectively. Hypoechoic ultrasound findings were less frequently found in the transition zone of the prostate, but the rate of CaP detection was the same as in the peripheral zone of the prostate. Conclusions:The transrectal ultrasound pattern of the prostate yields important information about the presence of carcinoma of the prostate. Especially hypoechoic lesions indicate the presence of CaP in a significant proportion of cases. However, hyperechoic lesions and lesions of mixed or irregular echogenicity were found to contain cancer in significant numbers as well, and should therefore be considered to be suspicious for cancer when performing transrectal ultrasound of the prostate. Directed biopsy of irregular ultrasound patterns in the prostate seems therefore to be recommendable. / Hintergrund: Der transrektale Ultraschall ist die häufigste bildgebende Untersuchung zur klinischen Beurteilung der Prostata. Zur Diagnostik des Prostatakarzinoms (PCa) hat sich die ultraschallgesteuerte Sextanten-Biopsie als Standardverfahren etabliert. Eine gezielte Biopsie irregulärer Ultraschallbezirke ist hier nicht vorgesehen. Es ist jedoch bekannt, daß sonographisch echoarm erscheinende Areale suspekt für die Präsenz eines PCa sind. Die Wertigkeit nicht einheitlicher oder echoreicher Ultraschallmuster ist jedoch bisher nicht zweifelsfrei geklärt. Ziel der vorliegenden Arbeit war es, mit einem Ultraschallgerät der neuesten Generation die Bedeutung der verschiedenen Ultraschallmuster bezüglich des Vorhandenseins von Prostatakarzinomen zu klären. Material und Methoden: 265 Patienten mit erhöhten PSA-Serumwerten oder suspekten Tastbefunden der Prostata wurden in die prospektive Untersuchung eingeschlossen. Bei allen Patienten wurden systematische, ultraschallgesteuerte Prostatabiopsien, wie in der Sextantenbiopsie vorgesehen, und 4 Zylinder aus der Transitionalzone entnommen. Bei der Biopsie wurde jedoch gezielt die Punktion in Bereichen von – falls vorhanden – irregulärem Ultraschallmuster vorgenommen und das entsprechende Ultraschallbild dokumentiert. Ergebnisse: Bei 87 der 265 Patienten (32,8%) wurden Prostatakarzinome nachgewiesen. Biopsiezylinder aus isodensen Bereichen wiesen in 7,6% ein Prostatakarzinom auf. Die Karzinomhäufigkeit bei Biopsie von echoarmen und echoreichen Arealen sowie von Arealen mit unterschiedlichen Echomustern und von zystischen Arealen wurde mit 34,5, 26,9, 21,1 bzw. 0% ermittelt. Echoarme Befunde wurden seltener in der Transitionalzone nachgewiesen, waren jedoch dort in etwa gleicher Häufigkeit mit einem Karzinom verbunden wie in der peripheren Zone. Schlußfolgerungen: Das transrektale Ultraschallmuster in der Prostata liefert wichtige Hinweise auf das Vorhandensein eines Prostatakarzinoms. Insbesondere echoarme Läsionen deuten auf ein PCa hin. Echoreiche Läsionen und solche mit unterschiedlichen Echomustern enthielten jedoch Karzinome in so bedeutender Anzahl, daß diese Läsionen ebenfalls als karzinomverdächtig eingestuft werden müssen und auch eine gezielte Biopsie dieser Areale im Rahmen der Sextantenbiopsie empfehlenswert erscheint. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
9

Ultrassonografia em modo b e doppler pulsado para a avaliação da injúria renal aguda induzida em cães adultos / Bi-dimensional and pulsed doppler ultrasonography in acute renal injury

Bragato, Nathália 24 August 2015 (has links)
Submitted by Cássia Santos (cassia.bcufg@gmail.com) on 2016-07-13T15:30:28Z No. of bitstreams: 2 Dissertação - Nathalia Bragato - 2015.pdf: 2818133 bytes, checksum: 41fd54a7924c0c46c940cda51cda9f8a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-07-14T11:31:04Z (GMT) No. of bitstreams: 2 Dissertação - Nathalia Bragato - 2015.pdf: 2818133 bytes, checksum: 41fd54a7924c0c46c940cda51cda9f8a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2016-07-14T11:31:04Z (GMT). No. of bitstreams: 2 Dissertação - Nathalia Bragato - 2015.pdf: 2818133 bytes, checksum: 41fd54a7924c0c46c940cda51cda9f8a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2015-08-24 / Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq / Acute kidney injury (AKI) resulting from toxic or ischemic insults and usually affect the tubular portion of the nephron, the use of potentially nephrotoxic drugs such as gentamycin one of the main causes. Early detection allows the AKI appropriate intervention may prevent or mitigate damage to the tubular cell and the development of acute renal failure (ARF). Diagnosis requires a combination of techniques, and be effective employment ultrasonography associated with laboratory tests. Ultrasound allows assessment of morphology and renal echogenicity by taking on bi-dimensional mode (B-mode) and renal hemodynamics through the assessment with pulsed Doppler with resistivity and pulsatility indices calculation. In this study, AKI was induced in six dogs with 30mg/kg of gentamicin once a day, for 10 days, in order to confirm the importance of B-mode and pulsed Doppler ultrasound for the diagnosis, monitoring and prognosis determination. Dogs were followed for 45 days by clinical examination, urinalysis, serum urea and creatinine, urinary GGT dosing and ultrasound. Six healthy dogs were used as control group and followed the same moments. The results of this study demonstrated that ultrasound is earlier than changes in laboratory diagnosis of ARI, and is useful for monitoring and prognosis determination, since the ultrasound aspect returned to normal in most dogs after recovery and dogs with ARF had higher values of the volume, of the Doppler indices and the degree of echogenicity. / A lesão renal aguda resulta principalmente da ação de agentes nefotóicos e de isquemia renal que geralmente afetam a porção tubular do néfron, sendo o uso de medicamentos potencialmente nefrotóxicos, como a gentamicina, umas das principais causas. A detecção precoce da lesão renal aguda permite a intervenção apropriada podendo prevenir ou atenuar o dano à célula tubular e o desenvolvimento da insuficiência renal aguda (IRA). O diagnóstico requer a associação de técnicas, sendo eficaz o emprego do exame ultrassonográfico associado aos exames laboratoriais. A ultrassonografia permite a avaliação da morfologia e da ecogenicidade renal por meio do exame em modo bidimensional (modo B) e da hemodinâmica renal por meio da avaliação com o Doppler pulsado pelo cálculo dos índices de resistividade e pulsabilidade. No presente estudo a lesão renal aguda foi induzida em seis cães, com o uso de 30mg/kg de gentamicina uma vez ao dia, durante dez dias, com o objetivo de confirmar a importância da ultrassonografia em modo B e Doppler pulsado para o diagnóstico, acompanhamento e determinação do prognóstico. Os cães foram acompanhados durante 45 dias por meio de exame clínico, exame de urina, dosagem sérica de ureia e creatinina, dosagem de GGT urinária e exame ultrassonográfico. Seis cães saudáveis foram utilizados como grupo controle e acompanhados nos mesmos momentos. Os resultados deste estudo demonstraram que a ultrassonografia foi capaz de diagnosticar a lesão renal aguda mais precocemente que as alterações laboratoriais, além de ser útil para o acompanhamento e determinação do prognóstico, uma vez que o aspecto ultrassonográfico voltou à normalidade na maioria dos cães após a recuperação e, os cães que desenvolveram IRA apresentaram valores mais elevados do volume, dos índices Doppler e do grau de ecogenicidade.

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