Previous literature on LGBTQ+ people (lesbian, gay, bisexual, transgender, queer/questioning, and other sexual minorities) reports that this community experiences greater health problems than heterosexuals. LGBTQ+ people experience higher rates of chronic conditions, STIs, addiction, poor mental health, and cancer, which highlights the importance of capturing data regarding health. A growing concern is that social surveys fail to find meaningful ways to gather gender and sexuality data to understand possible health disparities for LGBTQ+ people. This study uses data from the General Social Survey to examine the physical and mental health outcomes of LGB people compared to straight people in a nationally representative sample of Americans. An analysis of potential disparities in the self-reported health of straight and LGB respondents finds that respondents who identified as bisexual reported significantly lower levels of self-rated health and more problems with mental health compared to respondents who identified as gay, lesbian, or heterosexual.

Global Positioning System (GPS) is a satellite-based navigation system that has been used widely both in civilian and military for positioning, navigation, timing and other position related applications. The hardware-based GPS receivers provide the least user flexibility. Thus, it is necessary to have Software-based GPS receivers for easy and quick implementation, simulation and analysis of algorithms. Software-based GPS receiver processes the GPS signal at the radio frequency or intermediate frequency depending on the hardware configuration of the receiver. In this development of the acquisition and tracking processes of the software receiver, the front-end device that converts the radio frequency signal from the antenna to an intermediate frequency is the Mitel 2021 GPS receiver board. An analog-to-digital (A/D) converter then digitizes the output signal from the RF front-end. The data is then processed using MATLAB programs to achieve acquisition and tracking of the GPS signals. The software GPS receiver can perform acquisition and tracking using different parameters and threshold values. This flexibility of operation allows weaker signals to be tracked and processed. In this software receiver design, the focus is on the acquisition and tracking of L1 band C/A code GPS signals used by most civilian applications. The purpose of this thesis is to develop the acquisition and tracking algorithms to extract the navigation data bits from the raw GPS signals. The navigation data bits provide all the necessary information to compute the pseudorange between the receiver and the visible satellites and determine the receiver location. Both MATLAB simulated GPS data and realistic GPS signals from a GSS 6560 simulator are used to verify the performance of the acquisition and tracking programs. The acquisition program is capable of locating the beginning of the C/A code and the carrier frequency to within the desired accuracy. From the output of the acquisition program, the tracking program can decode the navigation data bits. The tracking algorithm implemented is based on the block adjustment of synchronizing signal (BASS) method. / Master of Science

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De två viktigaste händelserna i varje man jordliv är födelse och död. Varje av dessa händelser händer en gång i en livtid. Varje individ kommer in i världen på en bestämd tid på en särskild dag. På samma sätt lämnar varje person denna värld på en särskild dag på en bestämd tid. Växelverkan av dessa två viktiga händelser definierar, till en stor grad, totalityen av den globala befolkningen på någon given tidsperiod. Huruvida det finns befolkningboom/explosionen, eller kollapsen i världen beror i sin helhet på dessa två naturliga källor. Några demographers, klassificerar emellertid flyttning (dvs. emigration och invandring eller inflyttning och ut-flyttning) som delen av källorna av befolkningtillväxt.Antecknar dessa händelser, som och, när de uppstår, inte för gyckel eller en avsluta till honom, men ganska som hjälpmedel till en avsluta. Befolkningen påverkar varje aspekt av människoliv, namely: ekonomiskt, politiskt, lagligt, socialt, kulturellt, miljö-, vård-, Etc. Det är för dessa, och annat lika viktigt resonerar att folk av vision liksom John Graunt (1620-1674); Thomas Malthus (1766-1834); Herrn James Steuart (1713-1780); William Godwin (1756-1836); och något liknande sökte, i de tidig sortdagar, att ge erkännande till befolkningen utfärdar. Detta upprättar faktumet att, även om de formella sätter in av demography, är en förhållandevis ny innovation, folk long har angå om storleksanpassa och kännetecknen av deras territoriella befolkningar för mycket en lång tid. Trots dess jättelika betydelse, verkar som om det lite tid och resurser kanaliseras in i befolkningledning i samtidaa tider.I Ghana som i många ett u-land mycket lite uppmärksamhet har givits sätta in av på varandra följande regeringar. Denna low-profile inställning in mot befolkning utfärdar, över åren, har motsatt påverkats landets samhällsekonomiska och politiska framsteg. Jag kan inte vara för fel att förutsätta att riktig utveckling har undsluppit mest afrikanska länder och framkallningsvärlden på stort främst, därför att sammanlagt av dessa länder riktig uppmärksamhet inte har varit fallen föra befolkningmaterier. Är det inte riktigt att brist av den riktiga metoden och resurser är det huvudsakligt orsakar av ledare seemingly care-free inställning in mot befolkning utfärdar i dessa ett u-land i förflutnan? Även om det kan verka, att många bevattnar, har passerat under överbrygga, och, att, saker verkar för att ha stupat apart (Chinua Achibe) där är alltid ett fönster av flykten, när alla dörrar är stängda.Informations- och kommunikationsteknologier (ICTs) är den nya utvecklingen av fönster och flyktruttar ut ur många hitherto oöverstigliga problem. Därför i detta te, skulle jag något liknande för att undersöka och undersöka hur ICTs och det berömda nya/sociala massmedia kan hjälpa att lätta problemet av non-registreringen eller den otillräckliga registreringen av livsviktiga händelser i Ghana. / THE two most important events in every man’s Earth life are birth and death. Each of these events happens once in a life time. Every individual comes into the world at a certain time on one particular day. In the same way, every person leaves this world on one particular day at a certain time. The interaction of these two important events define, to a large extent, the totality of global population at any given time period. Whether there is population boom/ explosion or collapse in the world as a whole depends on these two natural sources. Some demographers, however, classify migration (i.e. emigration and immigration or in-migration and out-migration) as part of the sources of population growth.Recording these events as and when they occur is not for fun or an end to itself, but rather as a means to an end. Population affects every aspect of human life, namely: economic, political, legal, social, cultural, environmental, health, etc. It is for these and other equally important reasons that people of vision such as John Graunt (1620-1674); Thomas Malthus (1766-1834); Sir James Steuart (1713-1780); William Godwin (1756-1836); and the like sought, in those early days, to give recognition to population issues. This establishes the fact that although the formal field of demography is a relatively recent innovation, people have long been concerned about the size and characteristics of their territorial populations for a very long time. In spite of its enormous importance, it appears that little time and resources are channeled into population management in contemporary times.In Ghana, as in many developing countries, very little attention has been given the field by successive governments. This low-profile attitude towards population issues has, over the years, adversely affected the country’s socio-economic and political progress. I may not be too wrong to postulate that true development has eluded most African countries and the developing world at large mainly because in all of these countries proper attention has not been given to population matters. Is it not true that lack of proper method and resources are the main causes of leaders’ seemingly care-free attitude towards population issues in these developing countries in the past? Even though it may seem that many waters have passed under the bridge and that, things seem to have fallen apart (Chinua Achibe) there is always a window of escape when all doors are closed.Information and Communication Technologies (ICTs) are the new generation of windows and escape routes out of many hitherto insurmountable problems. Therefore, in this thesis, I would like to explore and examine how ICTs and the famous new/social media may help alleviate the problem of non-registration or inadequate registration of vital events in Ghana.

Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal.

Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal

Transmissive spongiform encephalopathies (TSEs) are neurodegenerative diseases characterized by depositions of abnormally folded prion protein (PrPTSE ) in brain. PrPTSE is at present the only specific biochemical marker of human and animal TSEs. Diagnostic tests are based on the detection of PrPres after proteinase K digestion of brain homogenate using Western blot or on the immunohistochemistry of fixed brain tissue, which are both difficult and time consuming. In this work we focused on development of a new type of tests based on PrP detection without need of proteinase K digestion. As deposits of PrPTSE remain in the body for a long time, there is a substantial chance of them being nonenzymatically modified by glycation. The detection of glycated PrPTSE may have a potential to serve as a diagnostic marker. We prepared monoclonal antibodies specific for carboxymethyl lysine/arginine modified prion protein. Bacterially expressed and purified recombinant human prion protein (rhPrP) was modified by glyoxylic acid that introduces carboxymethyl groups on lysine and arginine residues present within the molecule of the protein. Modified rhPrP (rhPrP-CML) was used for immunization of laboratory mice and hybridoma cells were prepared. Screening of cell supernatants resulted in the selection of 4...

Transmissive spongiform encephalopathies (TSEs) are neurodegenerative diseases characterized by depositions of abnormally folded prion protein (PrPTSE ) in brain. PrPTSE is at present the only specific biochemical marker of human and animal TSEs. Diagnostic tests are based on the detection of PrPres after proteinase K digestion of brain homogenate using Western blot or on the immunohistochemistry of fixed brain tissue, which are both difficult and time consuming. In this work we focused on development of a new type of tests based on PrP detection without need of proteinase K digestion. As deposits of PrPTSE remain in the body for a long time, there is a substantial chance of them being nonenzymatically modified by glycation. The detection of glycated PrPTSE may have a potential to serve as a diagnostic marker. We prepared monoclonal antibodies specific for carboxymethyl lysine/arginine modified prion protein. Bacterially expressed and purified recombinant human prion protein (rhPrP) was modified by glyoxylic acid that introduces carboxymethyl groups on lysine and arginine residues present within the molecule of the protein. Modified rhPrP (rhPrP-CML) was used for immunization of laboratory mice and hybridoma cells were prepared. Screening of cell supernatants resulted in the selection of 4...

This thesis was conducted with the objective of reducing water consumption byoptimizing the cooling systems of steam sterilizers. As water is a precious resourcewith great environmental effects, it is important not to waste it. Consequently, thereis a need for a more resource-efficient cooling water system. The project focuses onthe development of a system that more efficiently regulates the cooling water utilization by optimizing temperatures. The goal of the project is to achieve a 20% reduction in water consumption of the GSS-91413 model steam sterilizer manufacturedby Getinge. In order to achieve the goal, changes were made to the cooling systemand control logic of the cooling system. By integrating a proportional valve at theoutlet of the cooling system, the system was pressurized with the coolant resultingin greater energy transfer between the condensate and the coolant. The developedcontrol logic incorporates process data combined with an equation-based approachthat utilizes temperature data to adjust the proportional valve leading to increasedcontrol of the flow of the coolant. As a result, the overall water consumption of thesystem was reduced by more than 50% while the maximal temperature of the systemdid not rise more than 1.5%. / Detta examensarbete genomfördes med målet att minska vattenförbrukningen genom att optimera kylsystemen i autoklaver. Eftersom vatten är en värdefull resursmed stora miljöeffekter är det viktigt att den inte slösas. Följaktligen finns ett behovav ett mer resurseffektivt kylvattensystem. Projektet fokuserar på utveckling av ettsystem som mer effektivt reglerar kylvattenutnyttjandet genom att optimera temperaturer. Målet med projektet är att uppnå en 20-procentig minskning av vattenförbrukningen för autoklavmodellen GSS-91413 tillverkad av Getinge. För att nå måletgjordes ändringar i kylsystemet och i kylsystemets styrlogik. Genom att integrera enproportionell ventil vid utloppet av kylsystemet trycksattes systemet med kylvätskanvilket resulterade i större energiöverföring mellan kondensatet och kylvätskan. Denutvecklade styrlogiken inkorporerar processdata kombinerat med ett ekvationsbaserat tillvägagångssätt som använder temperaturdata för att justera proportionalventilen vilket leder till ökad kontroll av kylvätskans flöde. Som ett resultat minskade dentotala vattenförbrukningen i systemet med mer än 50% medan systemets maximalatemperatur inte steg mer än 1.5%.