Este trabalho tem por objetivo comparar a eficácia da cola biológica de fibrina e da drenagem de aspiração pós-operatória na prevenção de complicações cirúrgicas como hematoma e seroma após a realização de ritidoplastia pela equipe da Clínica Rezende no Hospital Moinhos de Vento, na cidade de Porto Alegre/RS. Realizou-se estudo prospectivo, controlado, randomizado e duplo cego. Foram analisadas 72 pacientes, divididas em dois grupos de 36, sendo que no grupo dreno utilizou-se drenagem de aspiração e no grupo cola utilizou-se cola de fibrina. Quarenta e oito horas após a realização dos procedimentos, todas as pacientes foram submetidas a aferição ecográfica da lâmina de exsudato presente sob os retalhos cutâneos da face. O volume total médio foi de 3,21 mL no grupo dreno e 1,02 mL no grupo cola, com magnitude de efeito de 68,1% e intervalo de confiança de 55,3 a 77,2 e p <0,001. Com esses resultados, comprovou-se que a cola apresenta eficácia significativa, demonstrando que sua utilização é 68,1 % mais efetiva que a drenagem de aspiração na prevenção de hematomas ou seromas em ritidoplastia. / This study aimed to compare the efficacy of fibrin glue and suction drainage in preventing postoperative complications such as hematoma and seroma following rhytidoplasties conducted by the staff of Clínica Rezende at Hospital Moinhos de Vento in Porto Alegre, Brazil. A prospective, controlled, randomized, double-blind trial was conducted. The 72 patients assessed in the study were divided into two groups of 36 each, one treated with suction drainage and other with fibrin glue. Forty-eight hours after the procedures, all patients underwent ultrasound evaluation of the volume of exudate under facial skin flaps. The average volume of exudate was 3.21 mL in the drainage group and 1.02 mL in the fibrin glue group, with a size effect of 68.1%, 95% confidence interval of 55.3 to 77.2, and p <0.001. The results of this investigation significant favor the use of fibrin glue, showing that was 68.1 % more effective than suction drainage in preventing hematoma or seroma following rhytidoplasty.

Este trabalho tem por objetivo comparar a eficácia da cola biológica de fibrina e da drenagem de aspiração pós-operatória na prevenção de complicações cirúrgicas como hematoma e seroma após a realização de ritidoplastia pela equipe da Clínica Rezende no Hospital Moinhos de Vento, na cidade de Porto Alegre/RS. Realizou-se estudo prospectivo, controlado, randomizado e duplo cego. Foram analisadas 72 pacientes, divididas em dois grupos de 36, sendo que no grupo dreno utilizou-se drenagem de aspiração e no grupo cola utilizou-se cola de fibrina. Quarenta e oito horas após a realização dos procedimentos, todas as pacientes foram submetidas a aferição ecográfica da lâmina de exsudato presente sob os retalhos cutâneos da face. O volume total médio foi de 3,21 mL no grupo dreno e 1,02 mL no grupo cola, com magnitude de efeito de 68,1% e intervalo de confiança de 55,3 a 77,2 e p <0,001. Com esses resultados, comprovou-se que a cola apresenta eficácia significativa, demonstrando que sua utilização é 68,1 % mais efetiva que a drenagem de aspiração na prevenção de hematomas ou seromas em ritidoplastia. / This study aimed to compare the efficacy of fibrin glue and suction drainage in preventing postoperative complications such as hematoma and seroma following rhytidoplasties conducted by the staff of Clínica Rezende at Hospital Moinhos de Vento in Porto Alegre, Brazil. A prospective, controlled, randomized, double-blind trial was conducted. The 72 patients assessed in the study were divided into two groups of 36 each, one treated with suction drainage and other with fibrin glue. Forty-eight hours after the procedures, all patients underwent ultrasound evaluation of the volume of exudate under facial skin flaps. The average volume of exudate was 3.21 mL in the drainage group and 1.02 mL in the fibrin glue group, with a size effect of 68.1%, 95% confidence interval of 55.3 to 77.2, and p <0.001. The results of this investigation significant favor the use of fibrin glue, showing that was 68.1 % more effective than suction drainage in preventing hematoma or seroma following rhytidoplasty.

The main topic of the thesis was to examine the hydrophobicity of labeling adhesives in the state before drying, it means their resistance against condensated moisture. The problem was solved by measuremensts of contact angle between the drop of water and glue. Measurements of dynamic viscosity and wet tack were also performed for the sake of complex characterization of the glue properties. Comparison of properties among single-component adhesives based on the acrylic copolymers alkalised with various agents was made. The impact of starches and industrial additives on glues was determined by the analysis of primary physical and chemical parameters. The purpose of the measurements was to develop a formula of the glue with enhanced atmospheric moisture resistance, that also would have the required parameters in the equilibrium. Finally, some selected glue samples were practically tested for condensation water resistance. These tests were performed in a climatic chamber with water condensating conditions.

The thesis deals with verification of applicability of biogenic binders during casting of gray cast iron. Applicability of these binders for making moulds as well as cores was verificated. The introduction describes strength of cured mixture with biogenic binder including influence of additives and refractory coating. The main part describes process of manufacturing of castings being poured into the biogenic binder bonded moulds. Pouring castings with cores bonded with the same binder is described as well. The last part deals with assessment of the given tests. The thesis comprises photodocumentation of poured samples.

Oxidative degradation of adhesives based on silane terminated polypropylene oxide and polypropylene oxide (PPO) was studied. The combination of rapeseed oil and PPO as plasticizer in the parquet adhesive gave rise to oxidative degradation in contact with screeds of certain minerals. In order to investigate the degradation process in parquet adhesive two experimental approaches were employed in parallel. The first method was ageing of a solid adhesive-screed system at elevated temperature. It was done in order to evaluate the effect of contact between adhesives and screed in different adhesive-screed systems. Another purpose was also to identify the degradation procedure in a system resembling reality. The second method used was ageing of a soluble mixture of pure PPO with selected plant oils; in order to study the affect of oils unsaturations on the PPO by FTIR. FTIR was used to monitor the degradation of samples after different exposure periods. Unfortunately, interference from the adhesive additives made monitoring of the degradation process difficult in this approach. On the other hand, the optical inspection of the samples degradation process gave a clearer overview. A second method, looking only at two components mixed e.g. PPO and Oil, gave clear FTIR spectra showing that the oxidation process of rapeseed oil started in the period before fifteen days ageing at 75 oC. The combination of FTIR and optical inspection gave a clear image of the adhesive degradation process. Interaction between unsaturated carboxylic acid in the vegetable oils and PPO can increase the degradation rate of parquet adhesives by a radical mechanism. Another parameter affecting the degradation is the interfacial interaction between adhesive containing PPO-Rapeseed oil as plasticizer and screed with high alkalinity, porosity and humidity. The alkaline and humid conditions in the screed probably increase the hydrolysis of rapeseed oil. Further, the porosity of the screed provides a large surface area enabling the plasticizer to be exposed to plenty of oxygen from the air. Therefore, the plasticizer is not only exposed to hydrolysis but also oxidation. This would support the observation of migration of the rapeseed oil, since it is known that carboxylic acid has affinity to calcium sulfate anhydrite in the screed material. Migration and oxidation of rapeseed oils carboxylic acid generate radicals, which accelerate the degradation of PPO in the adhesive film. This process correlated with disappearance of PPO absorbance band from the spectrum.

High nitrous oxide (N2O) emission potential has been identified in hemiboreal forest on drained Histosols. However, the environmental factors regulating the emissions were unclear. To investigate the importance of different factors on the N2O emission, a modeling approach was accomplished, using CoupModel with Monti-Carlo based multi-criteria calibration method. The model was made to represent a forest on drained peat soil in south-west Sweden where data of fluxes combined with soil properties and plant conditions were used. The model outcome was consistent with measurements of abiotic (soil temperature, net radiation, groundwater level and soil moisture) and biotic responses (net ecosystem exchange and soil respiration). Both dynamics and magnitude of N2O emissions were well simulated compared to measurements (8.7 ± 2.1 kg N/ha/year). The performance indicators for an ensemble of accepted simulations of N2O emission dynamics and magnitudes were correlated to calibrated parameters related to soil anaerobic fraction and atmospheric nitrogen deposition (correlation coefficient, r ≥ 0.4). A weak correlation with N2O emission dynamics was also found for biotic responses (r ≥ 0.3). However, the ME of simulated and measured N2O emissions was better correlated to the ME of soil moisture (r = -0.6), and also to the ME of both the soil temperature (r = 0.53) and groundwater level (r = -0.7). Groundwater level (range from -0.8 m to -0.13 m) was identified as the most important environmental factor regulating the N2O emissions for present forest soil. Profile analysis indicated that N2O was mainly produced in the deeper layers (≥ 0.35 m) of the soil profile. The optimum soil moisture for N2O production was around 70%.

Previous studies of agricultural conditions in the Mekong Delta (MD) have identified soil compaction as an obstacle to sustainable production. A conceptual model for soil formation was presented to demonstrate the link between soil hydrology and plant response. Detailed studies of soil moisture dynamics in agricultural fields were conducted using a dynamic process-orientated model. Pressure head and water flow were simulated for three selected sites during a year for which empirical data were available. Daily meteorological data were used as dynamic input and measured pressure head was used to estimate parameter values that satisfied various acceptance criteria. The Generalised Likelihood Uncertainty Estimation (GLUE) approach was applied for calibration procedures with 10,000 runs, each run using random values within the chosen range of parameter values. To evaluate model performance and uncertainty estimation, re-sampling was carried out using coefficient of determination (R2) and mean error (ME) as the criteria. Correlations between parameters and R2 (and ME) and among parameters were also considered to analyse the relationship of the selected parameter set in response to increases/decreases in the acceptable simulations. The method was successful for two of the three sites, with many accepted simulations. For these sites, the uncertainty was reduced and it was possible to quantify the importance of the different parameters.

No description available.

Background: Conjunctival pedicle flaps are one of the most frequently employed surgical interventions used to address a variety of sight threatening corneal diseases in veterinary ophthalmic practice. Securing the conjunctiva to the cornea is typically achieved through suturing, which is technically challenging and can result in prolonged surgical times, increased corneal edema, increased scar tissue, foreign body reaction, suture abscess and dehiscence. In human ophthalmology, a number of sutureless techniques to affix ocular tissues are being explored. Specifically, these approaches include synthetic tissue adhesives, bioadhesives, and hydrogel sealants. The proposed advantages of adhesives over suture, include reduced operative times, watertight seals, decreased foreign-body sensation and inflammation, faster healing times and tissue regeneration with original architecture restoration. Objective. To evaluate the maximum tensile force a conjunctival pedicle flap is able to withstand with respect to different fixation methods, i.e., Tisseel® fibrin glue, ethyl cyanoacrylate adhesive, ReSure® hydrogel sealant, or 8-0 VICRYL suture. Animals Studied. Ex-vivo porcine globes Procedures. Following a 500-micron restricted depth lamellar keratectomy, conjunctival pedicle flaps were dissected and secured to corneal defects with either the bioadhesive Tisseel®, or the synthetic adhesives ReSure®, ethyl cyanoacrylate, or 8-0 VICRYL® suture. Harvested corneoconjunctival flap interfaces were clamped to an accelerometer and potentiometer device, and loaded under video surveillance until the point of failure. Peak load at failure was determined for each test and used to compare between sample types. Results. 40 flaps underwent tensile force testing, with 6 being omitted for dehiscence prior to tensile testing. Of the 34 tests included in analysis, 10 conjunctival flaps were secured with suture, 10 with cyanoacrylate, 8 with ReSure® hydrogel sealant, and 6 with Tisseel® fibrin glue. A significant increase in maximum withstood tensile force was recorded between sutured flap fixation when compared with cyanoacrylate glue (p=0.02474), ReSure® hydrogel sealant (p= 0.00000), and Tisseel® fibrin glue (p= 0.00002). Cyanoacrylate fixation was significantly stronger when compared with ReSure® hydrogel sealant and Tisseel fibrin glue (p=0.01194 and 0.01798 respectively). There was no significant difference in adhesion strength between ReSure® hydrogel sealant and Tisseel® fibrin glue (p=0.95675). Conclusions. Conjunctival pedicle flap fixation using 8-0 VICRYL® suture fixation was able to withstand significantly greater maximum tensile force application in comparison with the ReSure®, Tisseel®, or cyanoacrylate adhesives. / Master of Science / Conjunctival pedicle flaps are one of the most frequently employed surgical interventions to address sight threatening corneal disorders in companion animals. Due to its redundant nature and close proximity to the corneal surface, conjunctival tissue is readily available for grafting to the cornea. It is surgically dissected to appropriate size and repositioned over the corneal defect where it effectively aids in healing through direct provision of structural support and indirectly via its rich blood supply. Securing the conjunctiva to cornea is typically achieved through suturing, which is technically challenging and can result in prolonged surgical times, increased corneal edema, increased scar tissue, foreign body reaction, abscess and dehiscence. In human ophthalmology, a number of sutureless techniques to affix ocular tissues are being explored. Specifically, these approaches include synthetic tissue adhesives, bioadhesives, and hydrogel sealants. The proposed advantages of tissue adhesives over suture, include reduced operation times, watertight closures, decreased foreign-body reaction and inflammatory response, faster healing times and increased ability to induce regeneration of the original tissue architecture. The purpose of this study was to evaluate the maximum tensile force a corneoconjunctial pedicle flap is able to withstand with respect to four different fixation methods, 40 ex-vivo porcine globes underwent conjunctival pedicle flap procedures. Each pedicle flap was secured to cornea with either 8-0 Vicryl® suture, Tisseel®, ethyl cyanoacrylate, or ReSure®. After harvesting from the globe, the corneoconjunctival unions were clamped to an accelerometer and potentiometer device, and loaded under video surveillance until the point of failure. The peak load was determined for each test and used to compare between sample types.

Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2015-10-23T11:41:58Z No. of bitstreams: 2 Dissertação -Tatiane Souza Rodrigues Pereira - 2015.pdf: 12338914 bytes, checksum: c966794ae558bcc73711fb5a806a52dd (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2015-10-23T11:45:02Z (GMT) No. of bitstreams: 2 Dissertação -Tatiane Souza Rodrigues Pereira - 2015.pdf: 12338914 bytes, checksum: c966794ae558bcc73711fb5a806a52dd (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Made available in DSpace on 2015-10-23T11:45:02Z (GMT). No. of bitstreams: 2 Dissertação -Tatiane Souza Rodrigues Pereira - 2015.pdf: 12338914 bytes, checksum: c966794ae558bcc73711fb5a806a52dd (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2015-04-28 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq / Financiadora de Estudos e Projetos- Finep / The impermeabilization of Brazil watersheds have generated socio-economic and environmental impacts innumerable, which has resulton a dare for public administrations. This because most of the towns do not have an efficient drainage system, this causes the water seeps quickly into water streams that are not prepared to support this new level of streamflow, mainly towards the extreme rainfall events. Thus, the hydrological modeling appears like an important support tool for planning and management. However this tool is subject to limitations that must be ascertained through calibration and model validation in real field conditions. This calibration process has been the focus of research and discussion in the last 50 years, and the most currently accepted models are based on uncertainty those analysis to determine the parameters. This study aims at the assessthe development and calibration of the model rainfall-runoff UFGModel1.1 as well as analyze the uncertainty applied to the simulation of streamflow. For this purpose, we used methodologies of uncertainty analysis by means of the Monte Carlo methods (MC) and Markov Chain Monte Carlo (MCMC), which form the basis of the GLUE and DREAM algorithms, respectively, for estimating uncertainties.The results demonstrate that DREAM performs better than the calibrating the GLUE. The various sets of parameters found for both algorithms were considered great for model validation, enabling high efficiency of this precipitation events for medium at very strong with relatively narrow uncertainty limits for DREAM and great for GLUE. The parameter that showed lower sensitivity in the model was the Manning channel. / A impermeabilização das bacias hidrográficas brasileiras têm gerado inúmeros impactos sócio-econômicos-ambientais, o que tem resultado em um desafio para as gestõespúblicas. Isso porque, a maioria das cidades não possuem um sistema de drenagem eficiente, assim a água escoa rapidamente para dentro cursos d’água que nãoestão preparados para suportar esse novo patamar de vazões, principalmente frente a eventos de chuva extremos. Dessa forma, a modelagem hidrológica aparece como uma importante ferramenta de suporte ao planejamento e gestão. No entanto, tal ferramenta está sujeita a limitações que devem ser averiguadas por meio de calibração e validação do modelo em condições reais de campo. Este processo de calibração tem sido foco de pesquisa e discussão nos últimos 50 anos, sendo que atualmente os modelos mais aceitos são os que empregam análise de incerteza na determinação dos parâmetros. Este estudo, visa avaliar o desenvolvimento e calibração do modelo de precipitação-vazão UFGModel1.1, bem como analisar a incerteza aplicada na simulação das vazões. Para tanto, utilizou-se metodologias de análise de incerteza por meio dos métodos de Monte Carlo (MC) e Cadeia de MarkovMonte Carlo (MCMC),que formam as bases dos algoritmos GLUE e DREAM, respectivamente, paraestimação de incertezas. Os resultados demonstram que o DREAM realiza uma melhor calibração que o GLUE. Osvários conjuntos de parâmetrosencontrados, para ambos algoritmos, foram considerados ótimos para a validação do modelo, possibilitando alta eficiência deste para eventosde precipitação de médio à fortes com limites de incerteza relativamente estreitos para o DREAM e grandes para o GLUE.O parâmetro que apresentou menor sensibilidade no modelo foi o Manning do canal.