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AbstractKnutsson, Henrik (2008). Skolans Fostrande Roll, En studie kring arbetsmetoden ”Bra Val”School´s Educating Role A survey about the method Making Good Choice Examensarbete 15 högskolepoäng, SÄL 3:2, Lärarutbildningen, Malmö högskolaI min undersökning har jag försökt ta reda på hur eleverna på ett individuellt utformat program i Malmö, uppfattar arbetet med den individuella bedömningen av genomförandet av lektioner som vi kallar Bra Val. Metoden Bra Val har sitt ursprung i trappmodellen, Det är ditt val, hämtat från boken Ordning och reda i skolan, skriven av Edin och Drummond (2006). Arbetet bygger på att lärarens ledarskap skapa förutsättning för en social utveckling i skolan. Tillsammans med arbetet med veckorapporten i Bra Val skall eleven bli varse och lockas till goda val i undervisningen och lära sig stå för de konsekvenser valen innebär. Jag valde att göra en enkätstudie detta för att få ett så neutralt inflytande över svaren som möjligt. Svaren från enkäten har kompletterats med litteratur studier samt möte och samtal med författaren Mats Edin. Resultatet visar att vi har lyckats skapa positiv utvecklings spiraler hos eleverna. Den främsta slutsatsen är att eleverna upplever att de är hjälpt av arbetssättet med Bra Val i undervisningen, eleverna upplever att de aktivt tänker på att göra goda val i undervisningen och att de känner att de lyckas på lektionerna.

Pseudomonas aeruginosa is an important opportunistic pathogen. Many P. aeruginosa virulence factors are regulated by the AlgZ/R two component system. AlgZ is the sensor histidine kinase which phosphorylates AlgR, the response regulator. AlgR activates transcription of different gene targets based upon its phosphorylation state. The genes that encode AlgZ and AlgR are transcribed in an operon. While regulation of algR expression has been well studied, regulation of algZ expression has not. Using a pilW mutant in concert with algZTF-lacZ transcriptional fusion, we conducted a transposon mutagenesis to identify algZ regulators. We identified an unknown autoregulatory loop. The type IV pilus minor pilins prevent the phosphorylation of AlgR by AlgZ . This inhibition of the AlgZ/R system subsequently down-regulates both the expression of the fimU operon and the algZ/R operon. Because AlgR regulates virulence, it is possible that virulence can also be reduced by targeting activation of the AlgZ/R system.

“Partner project impact” with a focus on the form of collaboration's impact on subcontractors is the starting point of the work. Partnering is an area of knowledge that is unfortunately still placed in the background. From the labor market to teaching, the ignorance of partnering is noticeable. Whether it depends on the generation working in the industry or the lack of interest, is difficult to answer. This ignorance of the form of cooperation and its significance aroused interest in this report and the hope of creating a greater interest in partnering. With Byggdialog AB as a helping company and their extensive knowledge in the field of partnering, research has been done on how the work environment and finances affect the subcontractors in a partneringproject compared to other projects with, for example, a fixed-price contract.  Partnering is a way of working where you work together from an early stage towards a common goal and with open finances. The contractor must be involved at an early stage together with the customer to arrive at how to create the best product, where they include the subcontractors already in phase 1 to jointly develop the best way of working.  The economic factor of upcoming and ongoing projects is of great importance to companies and their choices for upcoming projects. Relationships and collaborations between all parties in the project, from client to main contractor and subcontractors will be a new factor that has to be considered before the next choice of project.  The purpose of this report is to investigate whether partnering has any impact on a project and the subcontractors in the project. The work compares projects with and without partnering to see if the open economy has any impact and if it affects the work environment and the work on site. The goal is to create an overall picture from client to craftsman and see if the form of cooperation has any significance. The work will be based on these issues.  • How do the subcontractors' craftsmen experience that partnering affects the work on site? o How does job satisfaction differ between projects with and without partnering? o How does the subcontractor experience that workinghours are affected by partnering? • For what financial reasons does a subcontractor take a job on a partnering project?  The method for examining the issues were carried out through interviews and questionnaires to examine the soft parameters that partnering is about, humans, relationships and cooperation. The interviewees will be all parties in the project to get the overall picture. In addition to these interviews, literature studies as scientific reports are used to increase the credibility of the results, but also to create a better whole of the study. The results and conclusions were based on the methods and are reported according to the points below. • Partnering has a positive impact on the workplace. The relationship between all subcontractors is experienced as more open and better when the financial self-interest disappears and the communication between all parties is clearer. • The work environment is perceived to be less stressful and thus increases well-being in the workplace. Through a good work attitude between each other and for the common goal, the risk of extra work on evenings and weekends is minimized. • Partnering creates security in a troubled market where you deal with the problems together and work together for a better project. A market with high competition makes it difficult to consider the options of choice for the next project. But good relations and cooperation are in many cases more profitable for the work environment and the economy, and are factors that affect the next choice of project.

The 802.11 standard defines the Wired Equivalent Privacy (WEP) and encapsulation of data frames. It is intended to provide data privacy to the level of a wired network. WEP suffered threat of attacks from hackers owing to certain security shortcomings in the WEP protocol. Lately, many new protocols like WiFi Protected Access (WPA), WPA2, Robust Secure Network (RSN) and 802.11i have come into being, yet their implementation is fairly limited. Despite its shortcomings one cannot undermine the importance of WEP as it still remains the most widely used system and we chose to address certain security issues and propose some modifications to make it more secure. In this thesis we have proposed a modification to the existing WEP protocol to make it more secure. We achieve Message Privacy by ensuring that the encryption is not breached. The idea is to update the shared secret key frequently based on factors like network traffic and number of transmitted frames. We also develop an Initialization Vector (IV) avoidance algorithm that eliminates IV collision problem. The idea is to partition the IV bits among different wireless hosts in a predetermined manner unique to every node. We can use all possible 224 different IVs without making them predictable for an attacker. Our proposed algorithm eliminates the IV collision ensuring Message Privacy that further strengthens security of the existing WEP. We show that frequent rekeying thwarts all kinds of cryptanalytic attacks on the WEP.

The cardiovascular system of Drosophila melanogaster consists of a cardiac tube composed of myogenic cardiomyocytes and associating non-contractile pericardial cells, pumping hemolymph into the open circulatory system. The cardiac tube, known as the dorsal vessel, is embedded in a highly regulated extracellular matrix environment, required to maintain cellular integrity and cardiac function. After embryogenesis, the dorsal vessel undergoes extensive physiological changes, relying on the extracellular matrix to adapt and remodel accordingly. Three extracellular matrix proteins are investigated throughout this thesis: Type IV Collagen, Laminin and Pericardin. Due to their localization, morphology, and role in early development, the pericardial cells are candidate cells responsible for dorsal vessel extracellular matrix deposition and regulation throughout post-embryonic growth. Using immunofluorescence techniques in combination with confocal microscopy, I characterize the association between pericardial cells and extracellular matrix proteins, and quantify extracellular matrix protein deposition at the dorsal vessel throughout post-embryonic development. Gene knock-down experiments assess pericardial cell contribution to extracellular matrix synthesis and deposition at the dorsal vessel in third instar larva. Moreover, I quantify extracellular matrix protein deposition at the dorsal vessel in the absence of pericardial cells. These data suggests that pericardial cells regulate extracellular matrix protein deposition, localization and contribute to proper cardiac morphology in post-embryonic development. / Thesis / Master of Science (MSc)

Canada is in the process of implementing a Deep Geologic Repository (DGR) to dispose of used nuclear waste. Adsorption behaviour of both Se(-II) and Tc(IV) onto granite, shale, limestone, illite, and MX-80 bentonite has been elucidated. Se(-II) adsorption onto granite and MX-80 bentonite displays a decrease in Rd with an increase in solution pH. Se(-II) adsorption onto granite decreases with an increase in solution ionic strength. Se(-II) adsorption onto MX-80 bentonite does not return evidence which supports an apparent effect due to the ionic strength. Tc(IV) adsorption onto shale, limestone, illite, and MX-80 bentonite remains constant as the solution pH increases. Ionic strength does not affect the magnitude of Tc(IV) adsorption across the adsorbents, however an increase in ionic strength accelerates Tc(IV) adsorption. Se(-II) surface complexation models are best simulated with the following surface complexes: ≡Feldspar_sSe-, ≡Biotite_sOH2HSe, ≡Albite_sSe-, ≡Montmorillonite_sSe-, and ≡Montmorillonite_sOH2HSe. Tc(IV) adsorption is best simulated with: ≡Biotite_sOTcO(OH), ≡Quartz_sOTcO(OH), (≡Feldspar_sOH)2TcO(OH)-, ≡Montmorillonite_sOTcO(OH), (≡Albite_sOH)2TcO(OH)-, ≡Illite_sOTcO(OH), and ≡Chlorite_sOTcO(OH). Se(-II) adsorption onto granite and MX-80 bentonite in CR-10 solution returns Rd values of (1.80 ± 0.10) m3∙kg-1 and (0.47 ± 0.38) m3∙kg-1, respectively. Tc(IV) adsorption onto granite and MX-80 bentonite in CR-10 solution returned Rd values of (1.47 ± 0.25) m3∙kg-1 and (2.19 ± 0.33) m3∙kg-1, respectively. Tc(IV) adsorption onto shale, limestone, illite, and MX-80 bentonite in SR-270-PW solution returned Rd values of (0.16 ± 0.10) m3∙kg-1, (0.44 ± 0.21) m3∙kg-1, (1.86 ± 0.44) m3∙kg-1, and (0.23 ± 0.10) m3∙kg-1, respectively. This thesis will further deepen the understanding of Se(-II) and Tc(IV) adsorption. / Thesis / Doctor of Philosophy (PhD) / Determining the adsorption of Se(-II) and Tc(IV) onto granite, shale, limestone, illite, and MX-80 bentonite is beneficial to choosing a location within Canada to locate a used nuclear fuel repository. This thesis aims to quantify the adsorption behaviour of Se(-II) and Tc(IV) in Ca-Na-Cl and Na-Ca-Cl solutions with respect to a varying solution ionic strength and pH. Quantification of the adsorption was accomplished with adsorption experiments used in conjunction with geochemical simulations. New simulated surfaces specific to granite, shale, and MX-80 bentonite have been developed to complete these simulations. A final achievement was quantifying the adsorption of Se(-II) and Tc(IV) in groundwater representative solutions specific to locations considered for the used nuclear fuel repository.

Fundamental to mammalian brain development is the integration of cell intrinsic and extrinsic signals that direct the proliferation and differentiation of neural stem cells. Precise expression of transcription factors together with other intracellular components instruct progenitor cell fate, whereas interaction with extracellular signaling factors refines this process. We have elucidated the composition of the cerebrospinal fluid that is the source of multiple extrinsic cues during brain development. The choroid plexus, a highly vascularized tissue located in each ventricle of the brain, actively secretes cerebrospinal fluid. By RNA sequencing, we obtained transcriptome data on the choroid plexi from lateral and fourth ventricles of the mouse brain and discovered that they include transcripts unique to each tissue. Transcription factor expression in the macaque and human choroid plexi suggests that positional identities of these tissues are conserved in the primate brain. Based on transcriptional results, we defined the choroid plexus secretome, a prediction of secreted factors from the choroid plexus. By quantitative mass spectrometry, we detected proteins secreted by each choroid plexus, and comparison of these proteomic results with transcriptional profiling suggests that choroid plexus transcriptomes contribute to availability of regionalized cerebrospinal fluid factors during development. In the second part of my dissertation research, I studied the role of DNA repair mechanisms in regulating neural stem cells. These studies focused on DNA LigaseIV, an essential component of DNA double-stranded break repair, during cerebral cortical development. Deficiency of LigaseIV activity caused by a missense mutation leads to LigaseIV syndrome, in which a key clinical feature is microcephaly. Using the Lig4 R278H mouse mutant, we found increased cell death in the developing cortex, contributing to reduced cortical thickness and cellularity in the anterior cerebral cortex. These results indicate that DNA LigaseIV is essential for proper cortical development. Together, these findings illustrate the complexity of regulatory mechanisms that guide brain development, requiring the integration of mechanisms from within and outside the cell. We have investigated two such mechanisms, extrinsic cues from regionalized cerebrospinal fluid and DNA LigaseIV. These results should provide greater insight into mechanisms of normal brain development and neuropathological states. / 2017-11-02T00:00:00Z

In this thesis, we sought to understand the use of emotions as a political tool within the context of Spanish History in the 15th century.  Using the theoretical and methodological approach of Emotional History, heavily influenced by Barbara Rosenwein, Piroska Nagy, and Damien Boquet; we go through the royal chronicles written by Diego de Valera and Alonso de Palencia, analyzing the uses of emotions as a way of controlling the narrative of the kingdom.  We see that emotions not only had a complex range of meanings and symbolism attached, but also that these were used to paint the image of monarchs in a brighter or darker light.

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