Experimento I: Foram utilizadas 60 borregas da raça Santa Inês com o objetivo de avaliar os efeitos de três taxas de crescimento até os 7 meses de idade. Os tratamentos foram delineados visando obter alta taxa de crescimento (ATC), moderada taxa de crescimento (MTC) e baixa taxa de crescimento (BTC). Foram avaliados o consumo de matéria seca, o ganho de peso corporal e as concentrações séricas de progesterona para a detecção da idade à puberdade. Foram verificados efeitos lineares (p<0,01) para o peso corporal e metabólico, sendo os maiores valores encontrados para os animais do tratamento ATC. Efeito linear (p<0,01) foi verificado para o ganho médio diário (GMD) sendo de 0,182; 0,156 e 0,136 kg/dia para os tratamentos ATC, MTC e BTC respectivamente. Borregas pertencentes ao tratamento ATC apresentaram maior conversão alimentar sendo os valores para o tratamento ATC de 6,1; MTC de 7,1 e BTC de 9,2 kg MS/ kg de ganho de peso. Verificou-se diferença (p<0,01) quanto a porcentagem de animais que atingiram a puberdade sendo o tratamento MTC com o maior número de borregas púberes até os 7 meses de idade (60%), seguida dos tratamentos ATC (45%) e BTC (15%)com peso médio de 39,3 kg de peso corporal, sendo 70% do peso adulto. Experimento II: As borregas utilizadas no experimento 1 com 37 Kg de PC entraram em estação de monta e após o parto receberam uma única dieta, sendo blocadas de acordo com o peso e dias de lactação. Observou-se efeito quadrático (p<0,01) na produção de leite em 3h (137,9; 150,1 e 104,4 g), efeito quadrático (p<0,05) para LCG (167,2; 178,9 e 129,4) e efeito quadrático (p<0,03) LCGP (216,5; 140,5 e 162,7). Os teores de gordura (9,8; 8,9 e 8,3%) e de proteína (4,2; 4,2 e 4,6 apresentaram efeitos lineares sendo (p=0,01) para gordura e (p<0,01) para proteína. Experimento III: Os objetivos deste experimento foram avaliar o efeito da inclusão de bagaço de cana-de-açúcar in natura (BIN) sobre o consumo e a digestibilidade aparente dos nutrientes, balanço de nitrogênio e os parâmetros ruminais de cordeiros Santa Inês. Quatro cordeiros providos de cânula ruminal com peso corporal (PC) médio inicial de 30kg foram alojados individualmente em gaiolas para ensaios de metabolismo. O tratamento controle positivo (CONT) consistia de uma ração de alto concentrado contendo de 10% de feno de coastcross (Cynodon sp.) na MS, sendo os demais tratamentos níveis crescentes de BIN em 10, 20 e 30% da MS, constituindo os tratamentos 10BC, 20BC e 30BC. As rações experimentais foram isonitrogenadas (13,75±0,25% PB). Não verificou-se efeito de tratamento (p>0,05) sobre o consumo de MS, MO, e PB em kg/dia e g/kg de PC 0,75; apenas sobre consumo de FDN com efeito linear (p< 0,01). O balanço de nitrogênio, assim como a concentração de acetato, propionato, butirato, concentração total de AGCC, amônia no fluido ruminal e a de digestibilidade aparente da MS, MO, PB e FDN não foram afetados pelos tratamentos. / Trial I: Sixty Santa Ines ewe lambs were used to evaluate the effects of three growing rates until 7 months of age. Treatments were defined to achieve high (HGR), moderate (MGR) and low (LGR) growing rates. The dry matter intake and average daily gain (ADG) were evaluated, well as serum levels of progesterone in order to detect the age of puberty. Linear effects (P<0.01) to body weight (BW) with values being 59.5, 61.4, and 58.0 to HGR, MGR and LGR, respectively. Linear effects (P<0.01) was also observed for average daily gain with values being 0.182, 0.156, and 0.136 kg/day, for HGR, MGR and LGR, respectively. The feed:gain ratio showed a linear effects (p<0.02) according to raw sugarcane bagasse inclusion in diet with values being 6.1, 7.1 (M) and 9.2 kgDM/kg BW for HGR, MGR and LGR, respectively. Linear effects (p<0.01) was observed for the percentage of animals of ewe lambs the reached puberty at 7 months of age, showing highest values for MGR (60%), followed by HGR (45%) and LGR (15%) treatment. Trial II: The same ewe lambs of Experiment 1 were bred at 37 kg of BW and after lambing they received a unique diet. The ewe lambs were blocked according to body weight and days in milking. According to the energy density increase in the diet, quadratic effects (p<0.01) was observed on milk production recorded in a 3-hour interval (137.9; 150.1 and 104.4 g), fat corrected milk (167.2, 178.9 and 129.4 g) and fat and protein corrected milk (216.5, 140.5, 162.7g). Fat (9.77, 8.92 and 8.35%) and protein (4.2, 4.2, and 4.6%) showed linear effects (P=0.01) for fat and (P<0.01) for protein. Trial III: The aim of this study was to evaluate the inclusion of raw sugarcane bagasse (RSB) on dry matter intake and apparent digestibility of nutrients, nitrogen balance and ruminal parameters of Santa Ines ram lambs. Four ruminally fistulated ram lambs averaging 30 kg of BW were placed in metabolism crates. The control treatment (CONT) consisted of a high concentrate diet with 10% of coastcross (Cynodon sp.) hay in the dietary DM and the others treatments consisted of 10, 20 and, 30% of RBS in the dietary DM. The diets were formulated to provide similar concentration of crude protein (13.75±0.25%). No effects were observed for DMI, OM, and CP in kg/day and g/kg of BW0.75. Linear effects (p<0.02) was observed for NDF intake according RBS inclusion. Variables, as well as total SCFA, acetate, propionate, and butyrate concentrations. Ruminal ammonia and apparent nutrient digestibility also did not differ among treatments.

No description available.

This study was designed to determine whether feeding an Aspergillus product would influence growth or feed utilization and intestinal mucosal cell function as indicated by uptake of methionine and glucose by isolated intestinal brush border membrane vesicles (BBMV). In Experiment 1, 24 weanling pigs were paired by sex, BW, and litter and were allotted, within pairs, to either an 18% CP corn-soy diet (control) or the same diet supplemented (.15%) with an Aspergillus product. There were no differences (P > .05) in ADG, daily feed intake, or feed/gain between the two groups. In Experiment 2, 24 weanling wether lambs were paired by BW and were randomly assigned within pair to a 14% CP diet containing 61.1 % cracked corn, 17.3% soybean meal, and 15% ground orchard grass hay (control) or the same diet fortified (.07%) with an Aspergillus product. There were no differences (P > .05) in ADG, daily feed intake, or feed/gain between the two groups. Enrichment of alkaline phosphatase in BBMV used in transport studies were 12.7-fold higher in pigs and 5.6-fold higher in lambs over the original homogenate. / Ph. D.

Two experiments were conducted with sheep to determine the nutritional value of 'Lathco' flatpea (Lathyrus sylvestris) hay. In experiment 1, a finishing trial was conducted with 50 group fed crossbred lambs (25 ewes and 25 wethers) fed diets consisting of 70% chopped forage and 30% ground corn grain for 70 d. Five pens of five wethers and five pens of five ewes were selffed diets in which the forage consisted of 100:0, 75:25, 50:50, 25:75, and 0:100 proportions of alfalfa (Medicago sativa L.) and flatpea hay. Feed efficiencies decreased linearly (P<.05) as flatpea increased in the diet. Linear decreases (P<.05) were obtained in kidney and pelvic fat, backfat, leg conformation, and yield grade with increased flatpea in the diet. Blood urea-N (BUN), ruminal pH and NH3-N increased (P<.005) as proportion of flatpea increased. Total volatile fatty acid (VFA) and acetate concentration decreased linearly (P<.005) and propionate, isovalerate, and valerate levels increased linearly (P<.01) with increased proportions of flatpea hay. In experiment 2, 30 wether lambs were fed diets consisting of 100:0, 75:25, 50:50, 25:75 and 0:100 proportions of chopped alfalfa and flatpea hays in a digestion trial. Neutral detergent fiber (NOE), acid detergent fiber (ADE), cellulose, hemicellulose and energy digestibilities decreased linearly (P<.01) with increased levels of flatpea hay. Nitrogen retention was not different between sheep fed the different diets. Apparent absorbtion and retention of Ca decreased linearly (P<.05) with increased level of flatpea hay Ruminal pH and NHa-N, and BUN increased linearly (P<.OOl) as flatpea was increased in the diet. Ruminal total VEA, acetate and acetate to propionate ratio decreased linearly (P<.001) and propionate, isobutyrate, isovalerate, and valerate levels increased linearly (P<.001) as level of flatpea increased. / Master of Science

Der Einfluss der Fütterungsintensität auf das Wachstum von Ziegenlämmern. Ziel der vorliegenden Arbeit ist es, die Auswirkungen einer Milchrestriktion während der laktogenen Aufzucht von Ziegenlämmern sowie Mechanismen des kompensatorischen Wachstums nach dem Absetzen der Tiere zu untersuchen. Im Literaturteil werden das kompensatorische Wachstum, die Einflussfaktoren welche die Kompensationseffekte bestimmen, mögliche Ursachen sowie die Auswirkungen auf das Tier beschrieben. Der eigenen Untersuchung liegen die Daten aus zwei Fütterungsversuchen mit insgesamt 58 Ziegenlämmern der Rasse Bunte Deutsche Edelziege im Alter von 7 bis 165 Tagen zu Grunde. In einem 2 x 2 faktoriellen Versuchsansatz wurden zunächst die Auswirkung einer Milchrestriktion um 40 % und eine anschließende zeitweilige Futterrestriktion um 40 % auf die Lebendmasse-entwicklung, die Futteraufnahme, Futteraufwand die Entwicklung der Inneren Organe sowie die Körperzusammensetzung der Lämmer untersucht. Die Ergebnisse sind im Hinblick auf mögliche Ursachen der Kompensationseffekte diskutiert. / The influence of different feed levels on the growth performance of goat lambs. This study investigated the effect of a milk restriction of preweaned lambs as well as the effects of compensatory growth after weaning. The literature part gives a overview of factors, which effect compensatory growth rates as well as reasons for the compensation of a waight deficite. The present study was carried out in 2 feeding experiments with 58 goat lambs (Bunte deutsche Edelziege) during the age of 7 to 165 days. The experiment investigated the influence of a restriction of milk (40 %) on prewaened lambs. After weaning the effect of a food restriction (40 %) on growth performance, food intake, food converting rate, development of internal organs and body composition of goat lambs was investigated. The results and possible reasons for the compensation effect are discussed.

Com o objetivo de avaliar a influência de teores crescentes de proteína bruta (PB) em dietas com alta proporção de concentrado para cordeiros deslanados, foram realizados dois experimentos: Experimento I (desempenho dos animais) e Experimento II (digestibilidade dos nutrientes). No Experimento I foram utilizados 48 cordeiros da raça Santa Inês (peso inicial de 18,4 ± 0,4 kg e idade média inicial de 86 ± 2 dias) em um delineamento experimental de blocos casualizados com 4 tratamentos e 6 repetições. As dietas experimentais continham 80% de concentrado e 20% de volumoso (10% bagaço-de-cana hidrolisado e 10% bagaço-de-cana in natura), com teores de 14, 16, 18 e 20% PB na matéria seca. Não houve diferença (P > 0,05) entre os tratamentos para consumo de matéria seca, ganho de peso, conversão alimentar e rendimento de carcaça. A concentração de N-uréico plasmático após 3 horas do fornecimento da alimentação não aumentou para as dietas contendo teores de PB acima de 16%. No Experimento II foram utilizados 5 ovinos da raça Santa Inês providos de cânulas ruminais (peso médio inicial de 43 kg e idade média inicial de 6 meses) em um delineamento experimental em quadrado latino 5x5. As dietas experimentais continham 80% de concentrado e 20% de volumoso (10% bagaço-de-cana hidrolisado e 10% bagaço-de-cana in natura), com níveis de 12, 14, 16, 18 e 20% PB na matéria seca. Não houve diferença (P > 0,05) entre os tratamentos para digestibilidade aparente da matéria seca, da matéria orgânica, da fibra em detergente neutro, da fibra em detergente ácido e do extrato etéreo. A digestibilidade aparente da proteína bruta e a retenção de N (g/dia) foram maiores (P<0,05) para as dietas com 16, 18 e 20% PB em relação às dietas com 12 e 14% PB. O aumento da concentração protéica da dieta proporcionou um aumento (P<0,05) na concentração de N amoniacal no rúmen, entretanto não teve efeito (P>0,05) nos valores de pH e na produção de ácidos graxos voláteis. / Two experiments were conducted to evaluate the effects of crude protein (CP) levels on high grain diets fed to ram lambs. In Exp. I (performance trial), 48 Santa Inês lambs (initial body weight 18.4 ± 0.4 kg and 86 ± 2 days old) were fed 4 experimental diets containing 14, 16, 18 and 20% CP, in a completely randomized block desing. Diets consisted of 80% concentrate and 20% sugarcane bagasse. There were no differences (P > 0.05) in dry matter intake, average daily gain, feed efficiency and dressing percentage. Plasma urea nitrogen concentration did not increase in diets containing more than 16% CP. In Exp. II (metabolism trial), 5 Santa Inês lambs (43 kg body weigh) fitted with ruminal cannulas were used in a 5x5 Latin Square design. Diets consisted of 80% concentrate and 20% sugarcane bagasse with 12, 14, 16, 18 and 20% CP.There were no differences (P > 0.05) in dry matter, organic matter, neutral detergent fiber, acid detergent fiber and ether extract apparent digestibilities in the total digestive tract. Crude protein apparent digestibility in the total digestive tract and N retention (g/day) were greater (P < 0.05) for diets with 16, 18 and 20% CP than for the diets with 12 and 14% CP. Ruminal ammonia-N concentration increased (P < 0.05) with increasing levels of dietary CP, however no differences (P > 0.05) were observed on pH and ruminal volatile fatty acids concentration.

Este estudo teve como objetivo estudar as influências de diferentes tipos de manejo de ovinos no nível de estresse e na qualidade de carne e carcaça sob a óptica do bem-estar animal. Foram utilizados 86 animais, confinados após o desmame em baias duplas ou baias coletivas, avaliando-se o comportamento e o ganho de peso dos animais. A reatividade dos animais foi avaliada através do comportamento durante o manejo em balança, nos momentos de embarque e desembarque, e durante a espera pré-abate. O transporte ao abatedouro foi realizado em um caminhão, dividido em dois compartimentos, um parcialmente aberto e outro fechado. Foram aplicados dois períodos de descanso pré-abate, de 1 hora ou 3 horas, após o desembarque. No frigorífico foram colhidas amostras de sangue após o transporte e antes do abate para análise sérica de cortisol, classificadas as carcaças quanto à presença ou ausência de contusões, medidas as temperaturas e pH das carcaças à 1 e 24 horas após o abate. Às 24 horas após o abate foram retiradas amostras do músculo Longissimus dorsi para análise da qualidade de carne, como cor, maciez objetiva e perdas totais ao cozimento. O número de animais por lote confinado influenciou o comportamento dos cordeiros, alterando o padrão de ingestão de alimento, mas não interferiu na reatividade e no ganho de peso destes. O acesso visual ao ambiente externo durante o transporte de cordeiros é um fator estressante, alterando o nível de cortisol sérico, mas não altera as características da carcaça e de qualidade da carne. O período de descanso antes do abate diminui o estresse e reduz os níveis séricos de cortisol dos cordeiros. No entanto, existe uma interação entre o transporte e o período de descanso pré-abate, com consequências diferentes na maciez da carne. / The aim of this study was to improve the knowledge about the influences of different managements practices of sheep in the stress level and meat and carcass quality, from the viewpoint of animal welfare. It was evaluated the behaviour and the weight gain of 86 young animals, confined in double pens or collective pens. The reactivity of the animals was assessed by the behaviour during the weighing procedures, at the moments of loading and unloading, and during the resting periods pre-slaughter. The transport to the slaughterhouse was made by truck. This truck was divided in two areas: in rear area was open and in front area was closed. After the arrival half of the group within each area was subdivided, corresponding of two different periods of resting: 1 hour and 3 hours after landing. After transport and before slaughter blood samples were taken for analysis of cortisol. The carcasses were classified for the presence or absence of injuries, and were taken measures of the temperature and pH at 1 and 24 hours after slaughter. 24 hours after slaughter, samples from the Longissimus dorsi muscle were taken for analysis of colour, tenderness and total cooking losses. The results showed that the number of animals per pen confined had influence in the behaviour of the lambs, by changing the pattern of food intake, but did not affect the reactivity and their weight gain. During the transport, the visual access to the external environment is a stressful factor, increasing the level of serum cortisol. However, does not affect carcass characteristics and meat quality. The rest period before slaughter reduce stress and reduce serum cortisol of lambs. However, there is an interaction between the transport and rest periods pre-slaughter, with different consequences on meat tenderness.

Os objetivos deste trabalho foram estimar parâmetros genéticos, com os modelos mistos reprodutor e animal, para características reprodutivas contínuas e discretas, bem como, predizer os valores genéticos dos reprodutores para características reprodutivas contínuas e discretas em ovinos da raça Santa Inês. Foram analisadas as características reprodutivas intervalo de partos (IDP, N=1.066), fertilidade ao parto (FP, N=1.006) e número de cordeiros ao parto (NCP, N=3.593) de ovinos com partos ocorridos entre os anos de 1998 a 2005. A característica FP foi expressa na forma de fêmeas paridas em relação às fêmeas cobertas, sendo codificada como \"1\" se pariu e \"0\", caso contrário e NCP, representou o número de crias nascidas por ovelha parida, codificada como \"1\" (simples) e 2 (múltiplos). O modelo reprodutor apresentou a característica de superestimar as herdabilidades para as características reprodutivas em relação ao modelo animal. As estimativas de herdabilidades, obtidas por modelo animal linear, foram 0,12, 0,23 e 0,16 para NCP, FP e IDP, respectivamente. As estimativas de herdabilidades, obtidas por modelo animal de limiar, foram 0,16, 0,15 e 0,10 para NCP, FP e IDP, respectivamente. As estimativas das correlações genéticas pelo uso de modelo animal linear, foram 0,13 (entre NCP e FP) e -0,21 (entre NCP e IDP). Já as estimativas das correlações genéticas, quando utilizado modelo animal de limiar, foram 0,81 (entre NCP e FP) e -0,52 (entre NCP e IDP). As correlações entre os valores genéticos preditos para 258 reprodutores avaliados variaram de 0,4835 a 0,8561 entre os modelos reprodutor e animal obtidos por metodologia linear e de limiar. Este fato sugere a existência de alterações significativas nas classificações dos valores genéticos preditos dos reprodutores em função do tipo de modelo e da metodologia utilizada na avaliação genética. / The aims of this study were evaluated genetic parameters with sire and animal mixed models, to continuous and discreet reproductive traits, as well as predict sires breeding values to continuous and discreet reproductive traits in Santa Inês ewes breed. The traits analyzed in this study were lambing interval (LI, N = 1,066), fertility (FR, N = 1,006) and number of lambs born (NLB, N = 3,593) of ewes with birth occurred among 1998 to 2005. The FR trait was expressed in form of delivered females in respect to sheltered females, been codified as \"1\" delivered and \"0\" otherwise. The NLB trait represented the number of fully formed lambs born per ewe lambing, codified as \"1\" (simple) and \"2\" (multiples). The sire model showed super estimate comportment in respect to animal model for reproductive traits heritabilities. The estimates of heritability obtained by linear animal model were 0.12, 0.23 and 0.16 for NLB, FR and LI, respectively. The estimates of heritability obtained by threshold animal model were 0.16, 0.15 and 0.10 for NLB, FR and LI, respectively. The estimates of genetic correlations using linear animal model were 0.13 (between NLB and FR) and -0,21 (between NLB and LI). However, the estimates of genetics correlations using threshold animal model were 0.81 (between NLB and FR) and -0,52 (between NLB and LI). The Pearson correlations between predicted breeding values for 258 sires varying by 0.4835 to 0.8561 between sire and animal models obtained by linear and threshold methodology. This fact suggest the existence of significative changes on sires predicted breeding values classifications by virtue of model type and used methodology on genetic evaluation.

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The objectives of this thesis were to investigate patterns of lamb pneumonia prevalence of a large sample of New Zealand flocks including an investigation of spatial patterns, to evaluate farm-level risk factors for lamb pneumonia, to determine the efficacy of a commercially available vaccine for the disease and to estimate the likely cost of lamb pneumonia and pleurisy for New Zealand sheep farmers. Data were collected by ASURE NZ Ltd. meat inspectors at processing plants in Canterbury, Manawatu and Gisborne between December 2000 and September 2001. All lambs processed at these plants were scored for pneumonia (scores: 0, <10% or ≥10% lung surface area affected) involving 1,899,556 lambs from 1,719 farms. Pneumonia prevalence was evaluated for spatial patterns at farm level and for hierarchical patterns at lamb, mob and farm levels (Chapter 3). The average pneumonia prevalence in Canterbury, Feilding and Gisborne was 34.2%, 19.1% and 21.4% respectively. Odds ratios of lambs slaughtered between March and May were vastly higher than those slaughtered in other months indicating longer growth periods due to pneumonia. Since pneumonia scores were more variable between mobs within a flock than between flocks, it was concluded that pneumonia scores were poor indicators for the flock pneumonia level due to their lack of repeatability. There was no statistically significant spatial autocorrelation in pneumonia prevalence for any region, hence lamb pneumonia appeared to be largely independent of topographical and geo-climatic factors. A questionnaire-based case-control study was conducted investigating farm-level factors from a sample of farms with either high (case) or zero (control) pneumonia prevalence at slaughter (Chapter 4). Significant risk factors for case farms were: (1) shearing lambs on the day of weaning, (2) breeding ewe replacements on-farm (3) number of lambs sold (an indicator of flock size) and (4) increased percentage of lambs sold late in the season (March to May). Significant protective factors included: (1) set stocking lambs after weaning, (2) injecting lambs with Vitamin B12 at the time of tailing, (3) injecting lambs with Vitamin B12 at weaning. In Canterbury, flocks with Romney ewes and other ewes had a higher risk of pneumonia than those with fine wool type ewes (Merinos, Corriedales or Halfbreds). In a clinical trial, 8,364 lambs from seven commercial sheep farms with a history of lamb pneumonia were vaccinated with Ovipast Plus® or placebo by systematic random allocation within mob and farm. An assessment of the extent of pneumonic lesions was conducted at slaughter and lamb growth rate was monitored through the growth period (Chapter 5). The vaccination trial showed no statistically significant effect of Ovipast® vaccination on the extent of lung lesions at slaughter or ADG of lambs from the first treatment until slaughter. No significant differences were found between isolation rates of Pasteurella spp and patho-histological classifications from pneumonic lung samples of placebo and vaccinated lambs. A spreadsheet-based stochastic model was constructed to estimate the cost of lamb pneumonia and pleurisy to New Zealand farmers. The estimate was based on data of the effect of pneumonia on lamb growth rate, distributions of pneumonia severity, prevalence of moderate to severe pneumonia (≥10% lung surface area) and pleurisy prevalence (Chapter 6). The simulated annual average cost of pneumonia was NZ $28.1 million and that of pleurisy NZ $25.1 million. The combined cost of pneumonia and pleurisy to New Zealand farmers had an average of NZ $53.2 million (95% stochastic interval = $32.4-$78.9 million), or US $31.9 million per annum. This would equate to NZ $2.32 per lamb. In comparison, animal health, shearing expenses and feed expenses cost NZ $2.37, $2.62 and $1.85 per lamb, respectively. This research has demonstrated sub-clinical pneumonia to be a widespread disease in the New Zealand sheep farming population while previous research has focussed on case studies of affected farms. The estimated costs of pneumonia and pleurisy to New Zealand farmers ($53.2 million) highlight the financial effects of these diseases and the need for further research. We also found that the commercially available vaccine could neither prevent sub-clinical effects (lamb growth rate) nor clinical manifestations (pneumonic lung lesions) of lamb pneumonia. The case-control study has revealed farm-level factors which, in the absence of effective vaccines, indicated management practices that farmers might perceive as opportunities to control lamb pneumonia. However, it is advisable to evaluate the efficiency of such management changes. Pneumonia is aetiologically complex disease involving the interplay of many environmental, host and pathogen factors. It is also a difficult disease to study in the absence of diagnostic tests in live animals. However, further research should focus on the development of management changes until effective vaccines are available. A starting point for this research would be to evaluate the impact of such management changes in reducing the incidence of lamb pneumonia. More specifically, the roles of stress during crowding of lambs for extended periods warrants further investigation. The development of efficient vaccines requires an analysis of pathogens, especially Pasteurella (Mannheimia) haemolytica and Mycoplasma species, the sources of infection, their strain diversity and transmission dynamics.