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Über den Einfluss von Naloxon auf kardiopulmonale und metabolische Parameter, auf Körpertemperatur, Schmerzempfinden und psychischen Zustand bei FahrradergometerarbeitArentz, Thomas, January 1987 (has links)
Thesis (doctoral)--Köln, 1987.
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Analýza historických léčivých přípravků naloxonu, adrenalinu a efedrinu. / Analysis of Historical Pharmaceutical Preparations of Naloxone, Adrenaline and Ephedrine.Nováková, Lucie January 2015 (has links)
The aim of the thesis was to analyze the historical pharmaceutical preparations, including the determination of the active substance and identify theirs possible degradation products. A historical pharmaceutical preparation of naloxone was analyzed by mass spectrometry. Historical pharmaceutical preparations of adrenaline and ephedrine were analyzed by UHPLC-MS and were quantified using a calibration curve. In the historical injection solution of naloxone, "NARCAN", dated around 1980, there were no significant degradation products and the measured mass and UV spectrum was consistent with the spectrum of naloxone. The analyzed sample of naloxone was stable even after 35 years of storage. In the analyzed historical injection solution of adrenaline, "Adrenalin Hydrochlor., Dr. Heisler" (dated between 1917 and 1938) was determined 5.26 ± 0.11 % of the declared amount of adrenaline. In the measured spectras were noticeable degradation products, which have not been described in the literature yet and their identification was beyond the scope of this paper. The analyzed sample of adrenaline was almost completely degraded during about ninety years. The stability test carried out with four standard solutions of adrenaline proved influence of oxygen, light, temperature and time on the degradation of adrenaline. In...
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Effects of Naloxone on Kidney Weight, Macromolecular Constituents of Kidney and Cortisol Secretion in Fetal and Neonatal Pigs / Auswirkungen von Naloxon auf Nierengewicht, makromolekulare Bestandteile der Niere und Cortisolsekretion bei fötalen und neugeborenen SchweinenLi, Dingjian 19 July 2007 (has links)
No description available.
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Svenska polisers attityder & kunskap om naloxon i polisiärt arbete : En kvantitativ studie baserad på Teorin om Planerat Beteende enligt OOAS, OOKS & NaRRC-BMagnusson, Tobias, Molin, Jens January 2023 (has links)
Accidental drug poisoning has tripled in Sweden since the start of the 21st century, and statistically the country has had one of the highest overdose death rates in Europe. To reverse an opioid overdose, which is the main cause of drug related death, the antidote naloxone has the capacity of breaking the effect, and it is widely recommended as a safe drug with limited side effects. Police forces around the world have started to use naloxone and there is proven connection between its introduction and a reduced number of drug related deaths. However, Swedish police has not started to use or, as far as we know, investigate use of naloxone despite proven benefits. Since police sometimes are the first to arrive at the scene of an overdose, naloxone in a police context is important to study. This survey had its origin in the Theory of Planned Behavior, in accordance with the research instruments Opioid Overdose Knowledge Scale (OOKS), Opioid Overdose Attitude Scale (OOAS) and Naloxone-Related Risk Compensation Beliefs (NaRRC-B). This quantitative study had the purpose to measure and create knowledge about Swedish police officers' attitudes towards introducing and administering naloxone in police work, as well as their general knowledge regarding the antidote. The participants agreed that Swedish police officers should be equipped with naloxone to be able to save more lives (mean value = 3,9). The demonstrated benefits significantly outweigh the disadvantages of a possible implementation of naloxone within the Swedish police. Hence, it is essential that the Swedish Police Authority further investigates whether the use of naloxone can be a new working method to save more lives.
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Relevanz der Antidotagabe für das notärztliche präklinische Management von Vergiftungen unter Berücksichtigung der Bremer Liste - eine Analyse von 633 Fällen / Relevance of medically given antidotes in emergency prehospital management of intoxications considering the Bremer Liste - an analysis of 633 casesSchmidt, Melanie Julia 29 June 2017 (has links)
No description available.
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