Plasma- und Serumproben waren in früheren epidemiologischen Studien häufig das einzige biologische Material, das gesammelt und untersucht wurde. Diese Studien besitzen gerade durch ihren sehr langen Untersuchungszeitraum einen riesigen Informationsgehalt und wären ein unbezahlbarer Schatz für genetische Analysen. Oft ist aufgrund damals mangelnder Akquirierung jedoch keine genomische DNA verfügbar. Um die in Plasmaproben in geringer Menge vorkommende DNA verwenden zu können, extrahierten wir die DNA mit Hilfe von magnetischen Partikeln und setzten sie in eine Whole Genome Amplification (WGA) mittels Φ29-DNA-Polymerase ein. Wir stellten 88 Probenpärchen, bestehend aus einer WGA-Plasma-DNA und der korrespondierenden Vollblut-DNA derselben Person, zusammen und genotypisierten bei diesen neun hochpolymorphe Short Tandem Repeats (STR) und 25 SNPs. Die durchschnittliche innerhalb der Probenpaare auftretende Diskordanzrate betrug 3,8% für SNPs sowie 15,9% für STRs. Basierend auf den Ergebnissen der Hälfte der Probenpaare entwickelten wir einen Ausschlussalgorithmus und validierten diesen in der anderen Hälfte der Probenpaare. Mit diesem ist es möglich, zum Einen diejenigen Proben mit einer guten DNA-Qualität herauszufiltern, um Genotypisierungsfehler zu vermeiden, und zum Anderen jene Proben mit insuffizienter DNA-Qualität auszuschließen. Nachdem Proben, die fünf oder mehr homozygote Loci in dem 9-STR-Markerset aufwiesen, ausgeschlossen wurden, resultierte dies in einer Ausschlussrate von 22,7% und senkte die durchschnittliche Diskordanzrate auf 3,92% für STRs bzw. 0,63% für SNPs. Bei SNPs entspricht dieser Wert ungefähr der Fehlerquote, wie er auch bei Genotypisierungen mit Vollblut-DNA in vielen Laboratorien auftritt. Unsere Methode und das Ausschlusskriterium bieten damit neue Möglichkeiten, um zuverlässige DNA aus archivierten Plasmaproben wiederzugewinnen. Dieser Algorithmus ist auch besser geeignet, als nur die eingesetzte DNA-Menge in die WGA-Reaktion als Kriterium zu benützen. / Plasma and serum samples were often the only biological material collected for earlier epidemiological studies. These studies have a huge informative content, especially due to their long follow-up and would be an invaluable treasure for genetic investigations. However, often no banked DNA is available. To use the small amounts of DNA present in plasma, in a first step, we applied magnetic bead technology to extract this DNA, followed by a whole-genome amplification (WGA) using phi29-polymerase. We assembled 88 sample pairs, each consisting of WGA plasma DNA and the corresponding whole-blood DNA. We genotyped nine highly polymorphic short tandem repeats (STRs) and 23 SNPs in both DNA sources. The average within-pair discordance was 3.8% for SNPs and 15.9% for STR genotypes, respectively. We developed an algorithm based on one-half of the sample pairs and validated on the other one-half to identify the samples with high WGA plasma DNA quality to assure low genotyping error and to exclude plasma DNA samples with insufficient quality: excluding samples showing homozygosity at five or more of the nine STR loci yielded exclusion of 22.7% of all samples and decreased average discordance for STR and SNP markers to 3.92% and 0.63%, respectively. For SNPs, this is very close to the error observed for genomic DNA in many laboratories. Our workflow and sample selection algorithm offers new opportunities to recover reliable DNA from stored plasma material. This algorithm is superior to testing the amount of input DNA.

Student Number : 0515393R - MA research report - School of Literature and Language Studies - Faculty of Humanities / This study examines the effects of diaspora and displacement in characters as presented in Abdulrazak Gurnah’s Paradise, Admiring Silence and By the Sea. It looks at the role played by these effects in the construction of ideas of home and identity in the characters. Displacement is studied here against a backdrop of a long history of movements brought about by trading activities, exile and voluntary migrations. The texts are set in the east African coastal region, the islands and in Western countries such as England. The study relies on theories of postcolonialism and diaspora for its reading. The introduction places Gurnah’s work within the postcolonial archive by looking at his stance against the existing postcolonial discourses. It is also of importance to consider Gurnah’s biography and attempt to relate this to the view he takes as he narrates this geographical space in a postcolonial era. Chapter two looks at ideas of home as posited by different theorists in relation to the displaced and scattered characters he presents in these texts. Chapter three is concerned with how characters construct their identities against the ideas of ‘otherness’. In this chapter, I argue that Gurnah’s ideas of ‘otherness’ operate outside the (post)colonial idea of the same where the other is defined purely by difference in race. In chapter four I examine the significance of the preponderance of violence in the families presented by Gurnah. I investigate the connection between this perpetration of violence in the family and the idea of an elusive ‘paradise’ which runs through all Gurnah’s texts. The conclusion summarizes my major findings about Gurnah’s presentation of diaspora and displacement in the East African coast and the islands, and how he uses different structures like the home, self and the family to do this.

The aim of this essay is to study population change in tourism intensive mountain municipalities. Then to investigate whether center displacement takes place from the municipality center to the area with growing tourism. Areas of growing tourism have in this study been delimited to ski resorts. To answer the study’s purpose and questions, both quantitative and qualitative methods have been used. Population statistics have been used to explain population change in Swedish mountain municipalities. Population statistics showed that there are four mountain municipalities that have a shrinking population in the municipality and in the municipality center, while there is a ski resort with population growth in the municipality. These mountain municipalities are Dorotea, Malung-Sälen, Storuman and Härjedalen. Interviews with officials from these municipalities have been used as a complement to analyze the findings from the population statistics. The result of the interviews shows that the ski resorts have characteristics of being so-called ‘center’ with reference to the center-periphery model. At the same time, it also appears that the informants do not think that it is possible to talk about any tourism-driven center displacement. At least not with regard to public service. The municipality house will be remain located where it is today. Based on the given results, this essay conclude that ski resorts should be regarded as commercial centers and that the municipality center is the public center. From this aspect this study also conclude that there is possible to talk about a patriell center displacement from the municipality center to the ski resorts. Which, based on this study, is explained as commercial. The study also conclude that the commercial supply is dependent on the tourist visitors and those who work on the ski resorts, where the result shows that much of those who live in the ski resorts work in the touristindustry. In this way, the commercial center displacement also becomes tourism-driven.

Os tratamentos da oclusão levaram à escolha da relação cêntrica (RC) como posição de referência devido à sua reprodutibilidade, o que favorece maior precisão do diagnóstico. As interferências oclusais e os conseqüentes deslocamentos condilares entre as posições mandibulares de RC e a máxima intercuspidação habitual (MIH) têm sido revelados como parte dos fatores etiológicos das disfunções temporomandibulares. Na tentativa de melhor esclarecer o papel dos deslocamentos condilares dentro do contexto da oclusão, morfológica e funcional, como fator de risco no desenvolvimento da DTM, este estudo transversal prospectivo propôs-se a avaliar os referidos deslocamentos. A amostra foi composta por 70 participantes, não desprogramados, divididos em grupo sintomático, segundo o critério RDC/TMD, e grupo assintomático. Para avaliação dos participantes, empregaram-se modelos de gesso montados em articulador Panadent. Foram obtidos registros de cera em MIH e RC, sendo este último obediente à técnica power centric (Roth). As diferenças entre as duas posições foram medidas nos três planos do espaço, em gráficos correspondentes aos lados direito, esquerdo e transversal, avaliadas quanto à magnitude e direção e comparadas quanto à sintomatologia e o gênero pela análise de variância. A possível correlação quanto à direção do deslocamento foi avaliada pelo teste qui-quadrado de homogeneidade. Para verificar a reprodutibilidade das medidas intra e interobservador foram calculadas correlações intraclasses e índice de Dahlberg. Os resultados mostraram repetibilidade e reprodutibilidade das medidas condilares. Nos indivíduos com DTM, os deslocamentos em valores médios absolutos no plano vertical foram de 1,48 mm do lado direito (IPC vert D) e de 1,72mm do lado esquerdo (IPC vert E). No plano horizontal foram de 0,63 mm do lado direito (IPC hor D) e de 0,64 mm do lado esquerdo (IPC hor E). No plano transversal (IPC trans) o valor médio do deslocamento foi de 0,41 mm. Os valores médios absolutos dos deslocamentos condilares em indivíduos assintomáticos foram de 1,22 mm no plano vertical do lado direito (IPC vert D) e 1,30 mm do lado esquerdo (IPC vert E). No plano horizontal do lado direito (IPC hor D), os valores médios foram de 0,63 mm e do lado esquerdo (IPC hor E) 0,63 mm. No plano transversal, o valor médio do deslocamento foi de 0,23 mm (IPC trans). Na comparação entre os grupos assintomático e sintomático, constatou-se que este último apresentou valores maiores quanto ao deslocamento vertical do lado esquerdo (E) (p=0,039) e no sentido transversal (p=0,015). Observou-se também nesse grupo maior prevalência de deslocamento no sentido distal quando comparado ao grupo assintomático. Na associação entre a sintomatologia e a direção de deslocamento, verificou-se que o deslocamento condilar horizontal direito apresentou associação estatística com a sintomatologia (p=0,015). Não foram encontradas diferenças relativas à sintomatologia quanto ao gênero. O primeiro ponto de contato em RC mostrou-se localizado em sua grande maioria no segundo molar permanente, tanto no grupo sintomático (94,2%) quanto no assintomático (91,4%). / Centric relation (CR) is considered a reference position in the treatment of occlusion due to its reproducibility, thus favoring accuracy of diagnosis. Occlusal interference and consequent condylar displacement between CR and CO (centric occlusionmaxim intercuspation) have been revealed as part of the etiologic factors of temporomandibular dysfunction. In an attempt to better understand the role of condylar displacement in the context of morphologic and functional occlusion as a risk factor in TMD development, this transverse prospective study intends to evaluate the referred displacement. The sample was composed of 70 participants, not deprogrammed, divided into a symptomatic group, according to RDC/TMD criteria, and another, asymptomatic. From each subject, a wax registration in CO and CR was taken, the latter obeying the power centric technique (Roth). Cast models were mounted on a Panadent. articulator. Condylar displacement between CO and CR on three-spatial planes was measured on graphs corresponding to right, left and transverse sides, and appraised for magnitude and direction, determined by condilar position indicator instrumentation (Panadent-CPI). Analysis of variance test was used for symptom and gender comparison. The possible correlation for displacement direction and TMD was evaluated by the qui-square test of homogeneity. Inter and intraoperator reproducibility measurement error and reliability were calculated by intra-class correlations and the Dahlberg index. Low error showed high reliability and reproducibility. In TMD individuals, absolute mean values of condylar displacements in the vertical plane were 1, 48 mm on the right side (CPI vert R) and 1,72mm on the left side (CPI vert L). In the horizontal plane were 0,63mm on the right side (CPI hor R), and 0,64mm on the left (CPI hor L). In the traverse plane (IPC trans), mean value of displacement was 0,41mm. The absolute mean value of condylar displacement in asymptomatic individuals was 1,22 mm in the vertical plane on the right side (CPI vert R), and 1,30mm on the left side (CPI vert L). In the horizontal plane on the right side (CPI hor R) were 0,63mm and on the left side (CPI hor L), 0,63mm. In the tranverse plane (CPI trans) the mean value was of 0,23mm. Comparing asymptomatic and symptomatic groups it was verified that the latter presented larger values in vertical displacement on the left side (p=0,039) and in the transverse plane (p=0,015). In this group, larger displacement prevalence was also observed in distal direction when compared to the asymptomatic group. In the association between symptoms and displacement direction, it was verified that horizontal condilar displacement of the right side presented statistical association (p = 0,015). It was noted that, three-dimensional condylar displacement was found in both symptomatic and asymptomatic individuals. No correlation was found between patient gender and the presence of TMD symptoms. The initial premature contact in CR was detected, in most of the cases, on the second permanent molar, in both symptomatic (94,2%) and asymptomatic (91,4%) group.

Compreender deformação e seus métodos de monitoração é essencial na prevenção de acidentes e na manutenção de obras de engenharia civil. O GPS vem se destacando como uma tecnologia poderosa no controle de deformações de estruturas. O objetivo desta pesquisa é fornecer parâmetros para análise do comportamento de uma estrutura, por meio de experimentos e simulações com o uso do GPS. Sistemas e etapas envolvidos na monitoração de deformação são revisados e apresentados. Com o programa científico GIPSY, obtém-se a repetibilidade e a série temporal dos pontos localizados num edifício. O comportamento dos tabuleiros de um viaduto é analisado, com base nos dados GPS. Determinação de deslocamentos e de parâmetros de deformação, torna-se possível, com a realização de simulações. Utiliza-se uma placa para simular estes parâmetros, os quais relacionam-se com as observações em função de um modelo matemático. Elementos adicionais, como dilatação e deformações principais, além de alongamentos unitários e distorções, são determinados. Para verificação de estabilidade, realiza-se o teste de congruência global. / To understand strain and monitoring methods is essential in the prevention of accidents and in the maintenance of works of civil engineering. GPS has been increasingly becoming a powerful technology in the control of strains of structures. The aim of this research is to determine parameters for analysis of the behavior of a structure, by using simulation model and GPS. A review of systems and stages involved in the monitoring strain are revised and presented. With the scientific program GIPSY is obtained the repeatability and time series of the points located in a building. The behavior of the decks of a viaduct is analyzed with base in the data GPS. Determination of displacements and of strain parameters becomes possible with simulations. A plate is used to simulate these parameters and the mathematical model relates them with observations. Dilation or the principal strains are determined. In order to verify stability, it is carried out a global congruent test.

A avaliação completa do sistema estomatognático é essencial para o diagnóstico e plano de tratamento ortodôntico. Não se devem apenas avaliar aspectos estáticos da oclusão, mas também os funcionais, pois estes últimos podem mostrar-se alterados e envolver um ou mais componentes do sistema estomatognático, entre eles, a articulação temporomandibular (ATM). Uma das alterações encontradas com freqüência é o deslocamento de disco articular, o que pode interferir no prognóstico e, eventualmente, comprometer o resultado do tratamento ortodôntico. Na tentativa de contribuir para o reconhecimento dessas alterações, este estudo teve como finalidade avaliar a concordância entre dois examinadores calibrados em relação ao diagnóstico de deslocamento de disco articular, comparar a percepção dos pacientes aos ruídos com os dados do exame clínico e eletrovibratografia, além de checar a possível equivalência entre o exame clínico e eletrovibratografia, como métodos de detecção do deslocamento de disco articular. A amostra foi composta por 60 voluntários, divididos igualmente em 4 grupos com 15 participantes cada, definidos por meio do exame clínico e agrupados segundo o gênero e a presença ou ausência de estalo. O exame clínico foi realizado por dois examinadores treinados. A eletrovibratografia foi realizada por um único operador treinado, e empregou-se o programa SonoPAK (Bioresearch Inc.). Para análise dos resultados de concordância entre ambas as técnicas e entre os examinadores, foi utilizado o coeficiente kappa. Os resultados mostraram excelente concordância inter examinadores na realização do exame clínico, concordância satisfatória entre os relatos de ruídos referidos pelos pacientes quando comparados ao exame clínico e eletrovibratografia e concordância também satisfatória entre os dois métodos estudados. / The complete evaluation of the stomatognathic system is essential to the diagnostic and orthodontic treatment plan. It should not evaluate only the occlusal static aspects, but the functional aspects, because the latter could be altered and one or more components of the stomatognathic system could be involved, including the Temporomandibular Joint (TMJ). One of the frequently found alterations founded frequently is the articular disc displacement, which could affect in the prognostic, and, eventually the result of the orthodontic treatment. Trying to contribute to recognize these alterations, the purpose of this study was to evaluate the findings of two calibrated examiners on disk displacement diagnosis, to compare the patients joint sounds perception to the to the results found by the clinical examination and electrovibratography, and beyond that check the possible matching between the clinical examination and the electrovibratography as methods of disc displacement detection. The sample was composed of 60 patients, divided equally into 4 groups of 15 participants each, defined by clinical examination and grouped according to gender and to the presence or absence of the sound (click). The clinical examination was made by two trained examiners. The electrovibratography was made by only one only operator and the SonoPAK software was used (Bioresearch Inc.). The kappas coefficient was used to analyze of the results. They showed that the examiners findings were very close in the clinical examination, partially close on the joint sounds report told by the patients when compared to the clinical examination and eletrovibratography and reasonable equivalence between the two methods studied.

Esta dissertação analisa a questão dos deslocamentos emigratórios latinos americanos a partir das histórias orais de vida de uma família de bolivianos residente na cidade de São Paulo e de sua rede social afetiva. Além disso, estabelece um diálogo com as entrevistas dos pesquisadores bolivianos por meio da história oral temática confeccionada para este trabalho. Ao utilizar dois gêneros de historia oral, temos como perspectiva que esta dissertação contribua para os estudos migratórios contemporâneos. A temática central dessa pesquisa é verificar com se dá o processo de negociação de identidades entre a primeira e segunda geração da família boliviana escolhida para tal estudo, assim como entender o processo de mediação das identidades dos emigrantes com a sociedade brasileira. As identidades e as trajetórias de vida são concebidas como heterogêneas, em processo, em trânsito, articuladas por zonas de contato e trocas culturais. As memórias dos colaboradores revelaram campos de disputas, manifestam a diversidade e as ambiguidades das lembranças e esquecimentos. Deste modo, percebemos que as lembranças dos narradores são reelaboradas e passam por reapropriações culturais nos processos de deslocamentos continental e transfronteiriços no cenário latino americano. / This dissertation examines the question of Latin American emigration movements through life history interviews from a single family of Bolivian residents living in São Paulo and its affective social network. In addition, thematic oral history interviews with Bolivian intellectuals are analyzed. As a result of its use of two kinds of oral history interviewing methodologies, this dissertation contributes to contemporary migration studies. The central themes of this research are the negotiation of identities between the first and second generations of the family chosen for this study, and the mediation of the identities of Bolivian immigrants within Brazilian society. The identities and life trajectories of the narrators are perceived as heterogeneous, in process, in transit, and articulated by zones of contact and cultural exchanges. Recorded narrations reveal fields of conflict, and show diversity, ambiguity, and silences. Thus, we find that narrators memories are re-elaborated and go through a process of cultural appropriation as they cross borders and are dislocated within the Latin American continent.

Thesis advisor: Alicia H. Munnell / This thesis focuses on the employment of older workers and addresses the following questions: how people make their retirement decision, how changes in the Social Security benefit rules can encourage older workers to stay in the labor force longer, and what impediments older workers face on the labor market that can prevent them from working longer and interrupt their retirement plans. As the U.S. population ages, retirement and Social Security claiming decisions of older workers will have a significant impact on the U.S. economy. By the year of 2030 about 20 percent of the population will be 65 years old or older. The national retirement system generates less income in retirement than it did in the past. Rising Full Retirement Age, the shift of the private pension system from predominantly defined benefit to predominantly defined contribution pension plans, and increasing longevity will have to force older workers to stay in the labor force in the future to provide adequate income in retirement. Chapter one presents a dynamic stochastic retirement model that incorporates observed heterogeneity in educational attainment level. The assumption is that educational attainment level is highly correlated with the characteristics, such as preferences for work, types of jobs, and financial planning horizon that determine timing of retirement. A parsimonious model that incorporates heterogeneity in educational attainment level and stochastic earnings and health predicts the labor force participation rates and Social Security rates by age accurately. This model provides intuition for why college graduates tend to claim Social Security benefits and exit labor force later in life - longer life expectancy, non-physically demanding jobs, longer financial planning horizon, and deriving positive utility from work encourage college graduates to retire later. Chapter two develops and tests a policy rule regarding the availability of reduced early Social Security retirement benefits that would encourage older workers to stay in the labor force longer without amplifying the hardship on the more vulnerable population. The availability of Social Security retirement benefits at the current Earliest Eligibility Age (EEA) is considered the main impediment to longer working lives. Raising the EEA is thus considered the most powerful channel to raise the labor force participation rate. But raising the EEA would create hardship among workers with low private savings who are unable to work or find employment until the higher eligibility age. This study proposes and analyzes a new approach to setting each worker's EEA based on an individual's average lifetime earnings--an Elastic EEA. Low average lifetime earnings will likely reflect either poor health or spotty work histories, both of which are associated with weak employment prospects and limited financial resources at age 62. Tying the EEA to the average lifetime earnings could thus protect many of these vulnerable workers while encouraging longer working lives and increasing Social Security monthly benefits for workers more capable of remaining in the labor force. Simulations suggest that an Elastic EEA would achieve its goal in providing higher employment rates and levels of consumption in retirement compared to the status quo. These simulations also demonstrate the limitations of structural retirement models used to estimate the effect of raising the EEA. By assuming the same probabilities of losing and finding a job for all individuals, these models underestimate the adverse effect of raising the EEA on the more vulnerable population. Although some older workers may like to stay longer in the labor force, they may have hard time holding on to their jobs due to displacement. Chapter three is devoted to the trends in displacement of older workers. Conventional wisdom says older workers are less likely to be displaced. However, the difference in displacement rates between younger and older workers disappeared in the 2006 Displaced Worker Survey (DWS). The increased vulnerability of older workers appears to be the reason for this convergence. To better understand the age-displacement relationship, this study takes advantage of the availability of job tenure information and consistent design of the DWS since 1996. Using a Blinder--Oaxaca decomposition, it analyzes the effect of changes in tenure, industry mix, and educational attainment on the displacement rates of younger and older workers. The results show that older workers are now more likely to be displaced than prime-age workers, conditional on education, manufacturing industry, and tenure. / Thesis (PhD) — Boston College, 2009. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Economics.

Neste trabalho, o objetivo central é contribuir para a formulação de um aporte teórico, concernente às Ciências Sociais, na área das relações entre Comunicação e Cultura sobre o conteúdo político-ideológico implícito nas manifestações culturais das classes subalternas e examiná-lo enquanto instrumento ampliador da margem de compreensão sobre as formas de produção e auto-reprodução destas classes. Através da metodologia dialética, estudamos as possibilidades de identificar, na esfera das manifestações populares subalternas, indicativos da presença de potenciais ideológicos mediante os níveis verificados de sublevação do homem perante processos de homogeneização do pensamento, em contradição às condutas de resistência, automovimento e auto-governo reais. Constatamos, nestes estudos, que as metodologia e filosofia historicistas atualmente estão predispostas às necessidades de transformação da sociedade. Identificamos sua base ideológica nas subjetividades de dispositivos sócio-culturais que da realidade das classes subalternas deverá vir à superfície através da práxis filosófica que conceba o nexo mundo-cultura-movimento. / The primary aim of this work is to help developing a theoretical contribution, concerning Social Sciences, to the area dealing with Communication and Culture. Essentially, it discusses the political-ideological content underlying cultural expressions of the subordinate classes, which is identified as an expanding instrument of the understanding limits concerning the means of production and self-reproduction of these classes. Through a dialectical methodology, we have studied the possibilities of identifying, in the scope of popular subordinate expressions, symptoms of the presence of ideological potential by evaluating the level of human rebellion when faced by procedures of homogenizing thought, as opposed to resistance behaviour, real self-movement and selfgovernment. We have established, in this important occasion, the predisposition of historicist methodology and philosophy to the needs of changing society. Furthermore, we have identified its ideological basis in the subjectivities of social and cultural devices which, from the reality lived by subordinate classes, will only come forward through a philosophical praxis that will conceive the nexus of world-culture-movement.

A presente dissertação traz reflexões sobre os processos de gentrificação combinando argumentações teóricas baseadas em modelos teóricos que preveem analises fundamentadas em oferta e demanda, e através da renda diferencial que possibilita a analise de um potencial de renda, unindose a teorias de deslocamento, teoria de filtragem e teoria do ciclo de vida familiar, assim como atrair para discussão teorias sobre centro e subcentros. Com esses conceitos sugere-se uma analise que transpasse o processo de gentrificação, observando qual a consequência do processo efetivado e com quais fenômenos ele pode vir a contribuir , assim como também, se observa quais fenômenos podem contribuir para que o processo de gentrificação ocorra. Após essas conceituações, apresentar-se-ão exemplos de processos de gentrificação, apresentados sobre a perspectiva de seus pesquisadores contribuindo, para uma compreensão mais abrangente sobre as causas e efeitos abordados no processo de gentrificação, através da percepção de suas características expostas em diversos casos que possuem espaços constituídos de forma única. Para assim conseguir-se uma base substancial na procura por indícios de processos da primeira e da segunda onda do processo de gentrifcação no município de São Paulo. / The present dissertation brings reflections on the processes of gentrification combining theoretical arguments based on theoretical models that foresee analyzes based on supply and demand, and through rent gap that allows the analysis of an income potential, joining theories of displacement, theory Filtering and family life cycle theory, as well as to attract theories about the center and subcenters for discussion. With these concepts, it is suggested an analysis that transcends the process of gentrification, observing the consequences of the actual process and with which phenomena it may contribute, as well as observing which phenomena may contribute to the process of gentrification occurring. After these conceptualizations, we will present examples of gentrification processes, presented on the perspective of their researchers, contributing to a more comprehensive understanding of the causes and effects addressed in the gentrification process, through the perception of their characteristics exposed in several cases which have uniquely shaped spaces. In order to obtain a substantial base in the search for indications of processes of the first and second waves of the process of gentrification in the city of São Paulo.