Orientador: Antonio Lázaro Sant'Ana / Resumo: Esta tese fundamentou-se em pesquisa com os jovens estudantes do curso Técnico em Agropecuária Integrado ao Ensino Médio na Modalidade Alternância da Escola Técnica Estadual (Etec) “Sebastiana Augusta de Morais”, de Andradina (SP), com o intuito de conhecer a vivência escolar do alternante, as relações com a família e a Escola, as perspectivas de futuro, buscando analisar se a Pedagogia da Alternância, como ferramenta pedagógica para a Educação do Campo, pode contribuir para a valorização do modo de vida rural e a profissão de agricultor familiar. Foram entrevistados os alunos do 2º e 3º ano, em duas etapas diferentes. Na primeira etapa utilizou-se de questionário semiestruturado com questões qualitativas e quantitativas, aplicado na forma de entrevista com todos os alunos, das referidas séries, que estavam presentes nos dias da pesquisa; na segunda etapa também realizada por meio de entrevistas, mas com outro questionário, aplicado somente aos alunos que residiam em assentamentos rurais. A pesquisa abrangeu também entrevistas com familiares de 11 jovens, no próprio lote, abordando questões pertinentes à vida familiar, à visão que tinham da Escola e do processo de sucessão do estabelecimento familiar e, por fim, foram ouvidos ainda três professores visitadores do referido Curso. Evidenciou-se que a Etec conseguiu conquistar os jovens de tal forma que todos gostavam de frequentar a escola e que a modalidade alternância foi importante referencial para os alunos filhos de assent... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: This thesis was based on research with the young students of the Technical Course on Agropecuária Integrated to High School in the Modality Alternation of the State Technical School (Etec) "Sebastiana Augusta de Morais", of Andradina (SP), with the purpose of knowing the experience The relationship between the family and the school, the future perspectives, seeking to analyze whether the Alternation Pedagogy as a pedagogical tool for Field Education can contribute to the valorization of the rural way of life and the profession of farmer Family. In the first stage, a semi-structured questionnaire was used with qualitative and quantitative questions, applied in the form of an interview with all the students, of the referred series, that were present in the days of the research; In the second stage also conducted through interviews, but with another questionnaire, applied only to students who lived in rural settlements. The research also included interviews with relatives of 11 young people in the lot, addressing questions related to family life, their vision of the School and the process of succession of the family establishment, and finally, three visiting teachers of the said course . It was evidenced that Etec managed to win the youngsters in such a way that everyone liked to go to school and that the modality alternation was important referential for the children of rural settlers, bringing closer and reinforcing the interaction between the young person, the family and the ... (Complete abstract click electronic access below) / Doutor

The study was undertaken to identify the factors that influence standard seven pupils when they choose whether to continue with mathematics at senior secondary level or not. The relative importance of the factors was also determined. The literature study identified the following factors: attitude towards mathematics, utility of mathematics, family members' influence, mathematics teacher's influence, peer group influence, achievement and gender. The empirical study dealt with the following: * A 77 item questionnaire was completed by 201 standard seven pupils. * The statistical analysis revealed significant differences between pupils who chose mathematics and those who did not, with regard to all variables except gender. * A regression analysis identified the most influential factors as achievement, family members' influence, attitude and the mathematics teacher. * The overall implications were: - Pupils be made to experience success so that their attitudes may change. - Parents must be involved in their children's education. / Psychology of Education / M. Ed. (Psychology of Education)

Le glycolipide Gb3/CD77 qui est fortement exprimé en surface des cellules de lymphome de Burkitt (LB) est le récepteur d’une toxine bactérienne la Vérotoxine-1 (VT-1). Notre équipe a montré précédemment que, dans les cellules de LB, la VT-1 induit une cascade apoptotique mettant en jeu les caspases et la mitochondrie. Mon travail a consisté à poursuivre l’analyse des bases moléculaires de ce processus, notamment en m’intéressant au rôle de la protéine pro-apoptotique Bid. Bid est un membre de la famille Bcl-2 qui est clivé par la caspase-8 au cours de l’apoptose et dont la forme tronquée (t-Bid) se relocalise à la mitochondrie. Grâce à l’utilisation de clones cellulaires de LB où Bid a été inhibée puis réexprimée sous forme non clivable et d’un inhibiteur de la caspase-8, nous avons montré que lors de l’apoptose induite par la VT1 : 1) la protéine entière Bid (full-length Bid ou FL-Bid) contrôle l’activation de protéines pro-apoptotiques Bax et de Bak ; 2) t-Bid et FL-Bid sont, toutes les deux, impliquées dans la libération des protéines pro-apoptotiques (cytochrome c et Smac/DIABLO) de l’espace intermembranaire de la mitochondrie vers le cytosol ; 3) FL-Bid contrôle l’homodimérisation de Bax et de Bak qui contribuerait à la libération initiale du cytochrome c et de Smac/DIABLO alors que t-Bid est nécessaire à l’hétérodimérisation de Bax et Bak qui permettrait l’amplification de cette libération. L’ensemble de ces résultats montre donc une coopération fonctionnelle entre Bax et Bak au cours de l’apoptose induite par la VT-1 et surtout met en évidence que l’activation de la voie caspase-8/t-Bid n’est absolument pas requise pour initier la mort cellulaire.Gb3/CD77 est aussi exprimé à la surface de certains lymphocytes B normaux, où il constitue un marqueur de différenciation mais sa fonction endogène reste encore indéterminée. Une deuxième partie de mon travail a consisté à essayer d’identifier le ligand physiologique de Gb3/CD77 pour comprendre son rôle biologique. Grâce à une analyse en spectrométrie de masse, nous avons identifié deux protéines potentiellement partenaires de Gb3/CD77 : la galectine-7 et la protéine S100A11. / The Gb3/CD77 glycolipid, which is strongly expressed in Burkitt's lymphoma (BL) cells, is a receptor for the bacterial toxin Verotoxin-1 (VT-1). Previously, our group has shown that VT-1 induces an apoptotic pathway in BL cells which is dependent on caspases and mitochondria. Here, we provide new insights into this pathway. A pro-apoptotic member in the Bcl-2 family, Bid is cleaved by caspase-8 and its truncated form t-Bid is translocated to mitochondria. Using LB cell clones where Bid was inhibited prior to being reexpressed as a non-cleavable mutated form (BID D59A) and a caspase-8 inhibitor to explore VT-1-induced apoptosis, we showed that 1) the full length Bid (FL-Bid) controls the activation of pro-apoptotic proteins Bax and Bak; 2) Both t-Bid and FL-Bid are involved in the release of pro-apoptotic proteins (cytochrome c and Smac/DIABLO) from the mitochondrial intermembrane space to the cytosol; 3) FL-Bid controls the homo-oligomerization of both Bax and Bak, likely contributing to the initial release of cytochrome c and Smac/DIABLO while t-Bid is needed for their hetero-oligomerization followed by amplification of the release. Together, these results reveal a functional cooperation between Bax and Bak during VT-1-induced apoptosis and, most importantly, that activation of caspase-8 and t-Bid is not required to induce the onset of cell death. Gb3/CD77 is also expressed in a proportion of normal B-lymphocytes where it constitutes a differentiation marker but whose function remains uncharacterized. In an effort to look for physiological ligands, we have used a biochemical approach followed by mass spectrometry analysis. Two proteins have been identified as potentially Gb3/CD77 partners, namely galectin-7 and protein S100A11.

A traumatic brain injury (TBI) is what its name suggests: an extremely traumatic event that affects the most supremely powerful but fragile organ that controls all our bodily functions and holds the essence that makes individuals unique. Some patients with a traumatic brain injury will recover without realising what the effect could have been and others will be left with effects that will last throughout their lives. “Many sufferers will remain severely incapacitated and a lamentably large number will become part of the statistics on the mortality after TBI” (Burns, 2008a:76). The impairments that an individual faces after a TBI will be dealt with in an acute rehabilitation setting. Significant emotions are experienced by patients with a traumatic brain injury. The researcher believes that this emotional reaction is also experienced by the family members. The event may be even more devastating to the family members, because of the impaired cognitive functions of the injured person. Ross and Deverell (2004:36) state that when individuals are diagnosed with disabling conditions, they experience strong emotional reactions. “Feelings of grief, anxiety, inadequacy, anger, guilt, vulnerability and confusion are some of the more common emotions that clients and their families experience when they encounter a disability in themselves or a family member” (Ross and Deverell, 2004:41). After a traumatic brain injury the patient is usually admitted to an intensive care unit (ICU). Once medically stable and able to participate in an active rehabilitation programme, provided this is authorised by the patient’s medical aid, the patient is transferred to a rehabilitation unit. While in ICU, the outcome is very uncertain and the the family often receives very limited support. Patients are often in a coma and unable to communicate. In working with TBI patients, the researcher found that family members receive very limited support, education on the condition and feedback on the patient’s medical state from team members, and therefore become very anxious when the patient is eventually transferred to a rehabilitation unit. In this study, the researcher focused on the family’s experience from the time of the patient’s admission into ICU until discharge from rehabilitation. During the rehabilitation process, family members are encouraged to support their family member in the rehabilitation unit. This is often very difficult for them, as it entails being confronted with reality and the often devastating impact of the injury. The focus of this study is on the experiences of family members while the patient with a TBI is in hospital and in the rehabilitation unit and the challenges they face. The researcher strove to understand the experiences of family members of patients with TBI, from ICU through until discharge from acute rehabilitation. The goal was to explore the experiences of adult family members of the traumatic brain-injured person in post-acute rehabilitation. The research question was: What were the experiences of adult family members of the person with a traumatic brain injury (TBI) during post-acute rehabilitation? A qualitative approach was used in this study, with a collective case study research design. The population for this study was all the family members of patients who underwent rehabilitation as a result of traumatic brain injury in the Life Eugene Marais Hospital, Pretoria, Gauteng. In this study purposive sampling was used to choose participants who were family members of TBI patients. The criteria for sampling of family members as participants were as follows. The patient <ul> <li> had suffered a traumatic brain injury;</li> <li> had undergone acute rehabilitation at Life Eugene Marais Hospital for the last four years;</li> <li> had completed rehabilitation, in other words had to be post discharge;</li> <li> lived in the province of Gauteng; and</li> <li> was able to speak and understand English or Afrikaans, irrespective of gender, race, religion, culture or age.</li> </ul> Eight participants who were family members of eight TBI patients were chosen for this study. Semi–structured individual interviews were conducted with participants. Interviews were voice recorded with the permission of the participants and were transcribed by the researcher. The data were analysed by the researcher and the themes and sub-themes generated from the data. The research findings were presented by providing a profile of the research participants and then presenting the themes and sub-themes, including literature control and verbatim quotes from the transcriptions. The themes included the following: Theme One – Understanding of TBI; Theme Two – Period of hospitalisation; Theme Three – Family members’ emotional experience of TBI; Theme Four – Period of rehabilitation; Theme Five – Period post discharge; Theme Six – Support systems; Theme Seven – Effects of TBI and Theme Eight – Future. The conclusions of this study are that traumatic brain injury (TBI) is experienced as severe trauma by family members, who struggle to cope not only initially but especially once the person is discharged and has to be cared for at home. In the long term this experience leads to changes in the family regarding structure, roles, functioning, relationships, communication, finances and social life. Recommendations in this study can be used by the multidisciplinary team to better understand the needs and experiences of the family members of TBI patients and by social workers to improve their intervention and support to these families. / Dissertation (MSW)--University of Pretoria, 2012. / Social Work and Criminology / unrestricted

(English) This diploma thesis deals with the issue of mental disorders and services provided to family members of people with mental disorder within a non-profit sector. The first part includes theoretical chapters which are processed by analysing available literature. The chapters inform about mental disorder, quality of life, and describe the care of people with mental disorders - particularly social skills and communication, housing, education, employment and leisure time. The theoretical part also focuses on social work with the mentally ill and includes a role of a social worker. In conclusion, the theoretical part describes the possibilities of supporting family members within the system of the care of persons with mental disorder, especially educational and psychoeducational programmes. The empirical part maps the current range of services for family members of people with mental disorder, and in connection with that, it determines what workers consider to be their benefit. Then, the views of family members on the psychoeducational programme and the current system of taking care of persons with mental illness were examined in a parent organization. To implement the research, I chose a qualitative approach. The method used was a questionnaire survey and group interviews. The results showed...

69 Abstract This diploma thesis deals with manifestations of a borderline type of emotionally unstable personality disorder and its influence on family members of people with this type of disease. The aim of this thesis was to present the experience of living with a person with BPD. Qualitative research, using the semi-structured type of interview, was conducted with three respondents, one man and two women. The data was evaluated using interpretative phenomenological analysis. The results show the negative effects of contact with the individual with the BPD and the psychological burden is also evident. The thesis could be beneficial for social and health workers who come into contact with people with the BPD and their loved ones within their practice. At the end of the thesis step are mentioned through which each of us can contribute to the improvement of the situation.

This thesis focus on the theoretical aspects of family enterprising and running a family business in the Czech Republic. The first part deals with the history of family enterprising and the importance of family businesses in the economy and society. This part also describes the specificity of family firms, advantages and diadvantages and common problems in family-owned business. The theoretical part of the thesis also analyse the stability of the family firms in recession and the challenges of a family business in Czech Republic. The second part of the thesis contains four czech family firms' case studies.

Il coinvolgimento di utenti e familiari nella progettazione, gestione e valutazione dei servizi di salute mentale consente di migliorare i servizi, facendo valere gli interessi e la prospettiva di stakeholders che spesso vengono visti esclusivamente come ricettori passivi di prestazioni. La tesi prende il via da queste considerazioni, legate ad approcci recovery oriented, con l’obiettivo di analizzare come le organizzazioni sociosanitarie possono favorire la partecipazione e accogliere il punto di vista degli utenti e dei familiari attraverso l’introduzione di pratiche innovative. Per raggiungere questo obiettivo si è scelto di analizzare due casi: il Fareassieme del Servizio di salute mentale di Trento e il Social Point del Dipartimento di salute mentale di Modena. Attraverso osservazione e interviste, sono stati raccolti dati qualitativi che hanno portato a una interpretazione complessa e sfaccettata. In particolare, sono emersi due versanti: (1) quello del cambiamento culturale necessario per introdurre nell’organizzazione un nuovo approccio centrato sulla partecipazione e (2) quello della formalizzazione delle nuove pratiche partecipative, con i risvolti positivi e negati dell’incardinamento nell’organizzazione. Nelle conclusioni, si ipotizzano possibili sviluppi per la ricerca futura e si elencano i suggerimenti operativi emergenti dalla ricerca per i manager dei servizi sociosanitari. / The participation of users and family members in the design, management and evaluation of mental health services can improve services, relying on the interests and perspective of the stakeholders that are often seen only as passive recipients of services. The thesis takes away from these considerations, related to recovery-oriented approaches. The aim is to analyze how organizations can promote the health and social participation and accept the point of view of users and their families, through the introduction of innovative practices. I analyze two Italian cases: “Doing Together” (a project of the Mental Health Service of Trento) and “Social Point” (a service of the Department of Mental Health of Modena). Two issues emerged from qualitative data: (1) the organizational cultural change related to the introduction of a new approach, centered on participation and (2) the formalization of the participatory practices, with positive and negative consequences. In conclusion, I propose possible development for future research and suggestions to managers of health services.

This is a dissertation Programme Postgraduate Sensu Strictu Nursing, School of Nursing and Pharmacy, Federal University of Alagoas. Given that cancer at some point in evolution of the disease patients need to solve food problems, nursing adopts guidance to patients and their families as part of their care process, thus seeking a comprehensive and humane care. Based on this finding , this paper focuses the response of family members of cancer patients to dietary changes presented by the patient seriously ill. Aims to identify the experience of handling the family regarding the power of family severely affected by cancer at home. Qualitative, descriptive and exploratory survey conducted via guided by the Family Management Style Framework model interviews - FMSF , conducted with 10 family caregivers home. The results indicate that the sample had as main characteristics the fact that the caregiver being a woman, aged 51-60 years percapta low family income and parental great proximity to the patient. The families identified the food situation as being inappropriate; view The food usually eaten to cause health disorders in the critically ill patient and difficulty in providing the satisfaction of the biopsychosocial demands related to the supply of food. From the speech was possible to describe the behavior of management having the family caregiver modified the patient's diet in line with what you believe is a healthy, family caregiver modified the preparation and supply of the diet, the family caregiver changed his own attitude. Thus, the consequence perceived by the caregiver which were reflected in the discovery of effective strategies and confirmation of their previously developed skills. / Tendo em vista que os pacientes oncológicos em algum momento de evolução da doença necessitam resolver problemas alimentares, a enfermagem adota a orientação aos pacientes e seus familiares como parte de seu processo cuidar, buscando assim uma assistência integral e mais humana. Com base nesta constatação, este trabalho tem como objeto a resposta dos familiares de pacientes oncológicos às alterações alimentares apresentadas pelo doente gravemente enfermo. Teve como objetivos conhecer a experiência de manejo da família referente a alimentação do familiar gravemente acometido pela doença oncológica no domicílio. Pesquisa qualitativa, descritiva e exploratória realizada através de entrevistas norteadas pelo modelo Family Management Style Framework - FMSF, com 10 cuidadores familiares. Os resultados apontam que a amostra teve como características principais o fato do cuidador ser mulher, na faixa etária de 51 a 60 anos, baixa renda familiar percapta e grande proximidade parental com o paciente. As famílias identificaram a situação alimentar como sendo inapropriada; a comida usualmente ingerida vista como causadora de transtornos a saúde do paciente gravemente enfermo e, tendo ainda dificuldade em proporcionar a satisfação das demandas biopsicossociais relacionadas ao fornecimento da alimentação. A partir das falas dos sujeitos foi possível descrever o comportamento de manejo tendo o cuidador familiar modificado a dieta do paciente em consonância com o que acredita ser uma alimentação saudável; a modificação do preparo e oferta da dieta; além do familiar ter modificado sua própria atitude quando não foi possível alterar a do paciente. Neste movimento, a consequências percebidas pelo cuidador se refletiram no descobrimento de estratégias eficientes na condução do manejo do problema alimentar e na confirmação de suas habilidades previamente desenvolvidas. Contudo, com o agravamento característico da evolução do câncer, o familiar se viu diante de um problema gradativo com evolução negativa, no qual percebeu-se impotente frente as questões de manejo.

Made available in DSpace on 2016-06-02T19:45:56Z (GMT). No. of bitstreams: 1 1272.pdf: 1037239 bytes, checksum: 22560af3e4c1baf3f460510bd8aca797 (MD5) Previous issue date: 2006-12-11 / Universidade Federal de Sao Carlos / Professionals responsible for education of children with disabilities not always find the way to make their family a partner. This study aims to identify and describe the behaviors of professionals that work in the school and family members that are propitious and maintainers of the effective and successful collaborative partnership. The study was carried out with four focal groups, composed exclusively either by family members or professionals, once there were two groups of family members (FAM1 and FAM2) and two groups of professionals (PROF1 and PROF2) of different schools. 13 family members and 18 professionals participate in the groups. In order to identify the principal components of this partnership two stages were carried out. In each stage two meetings were performed with each focal group, summing up 16 meetings. In Stage 1 the meetings aimed to identify the components of the collaborative partnership, in the first meeting, and to check the collected information in the range group in the second appointment. In Stage 2 each one of the focal groups was collated with the data obtained in the first stage, once family members were paralleled with the professional data and vice versa. The reactions to the data were registered, and afterwards checked in the second appointment. Through qualitative analysis the expected and desired behaviors of professionals and family members were identified and described to increase the probability of success and effectiveness of a collaborative partnership. The categories raised by the family members groups in relation to themselves were: to communicate with the professionals; to be responsible for the child s education; to keep adequate expectations; to accept the children s disability; to respect professionals. On the other hand, the family members expectations about professionals performance were: to communicate with family members; to communicate with other professionals; to be friendly; to separate personal problems from the professional activity; to promote student s development; to be attentive to family problems and to attempt to resolve them; to help family members keep suitable expectations; to incorporate to work suggestions provided by family members; to worry about the student out of school; to offer groups to parents; to respect students and family members; to offer orientation to family members. In their turn, the groups of professionals pointed the following categories in relation to the behaviors they expected of the families: to communicate with the professionals; to recognize the work of the professionals; to trust the developed work; to be responsible for the child s education; to believe in the child s development; to keep adequate expectations; to question the professionals properly; to certify the child s attendance to school; to visit the school; to take part in the activities. Concerning the performance themselves, the following categories were found: to communicate with family members; to show seriousness; to be sincere; to be impartial; to respect students and family members; to be aware of family members and students features; to motivate the participation of family members; to gather with family members; to show the family members the activities performed; to help family members keep suitable expectations. It is expected that, with the survey and the description of the categories, the professionals responsible for the education of children with disabilities and their family members can find their bearings in the search for the establishment of an effective and successful collaborative partnership. / Os profissionais responsáveis pela educação de crianças com deficiência nem sempre encontram o caminho para fazer da família uma parceira. O presente estudo tem como objetivo identificar e descrever os comportamentos emitidos por profissionais que trabalham na escola e familiares de crianças com deficiência que, na perspectiva dos dois lados, são propiciadores e mantenedores de uma parceria colaborativa efetiva e bem sucedida. O estudo foi conduzido com quatro grupos focais, compostos exclusivamente ou por familiares ou por profissionais, sendo que houve dois grupos de familiares (FAM1 e FAM2) e dois grupos de profissionais (PROF1 e PROF2) de diferentes escolas. Participaram dos grupos 13 familiares e 18 profissionais. A fim de identificar os componentes principais dessa parceria foram conduzidas duas etapas. Em cada etapa foram realizadas duas reuniões com cada grupo focal, totalizando 16 reuniões. Na Etapa 1 as reuniões tiveram por objetivo identificar os componentes de uma parceria colaborativa, na primeira reunião, e checar as informações coletadas no âmbito do grupo num segundo encontro. Na Etapa 2 cada um dos grupos focais foi confrontado com os dados obtidos na primeira etapa, sendo que familiares foram confrontados com os dados dos profissionais e vice-versa. As reações aos dados foram então registradas e posteriormente checadas, numa segunda reunião. Por meio da análise qualitativa foram identificados e descritos os comportamentos esperados e desejados por profissionais e familiares para aumentar a probabilidade de sucesso e efetividade de uma parceria colaborativa. As categorias levantadas pelos grupos das famílias em relação a si próprios foram: comunicar-se com profissionais; ser responsável pela educação do filho; manter expectativas adequadas; aceitar a deficiência do filho; respeitar os profissionais. Por sua vez, as expectativas das famílias sobre a atuação dos profissionais foram: comunicar-se com familiares; comunicarse com outros profissionais; ser amistoso; separar os problemas pessoais da atividade profissional; promover o desenvolvimento do aluno; estar atento aos problemas dos familiares e tentar resolvê-los; ajudar os familiares a manter expectativas adequadas; incorporar ao trabalho sugestões fornecidas pelos familiares; preocupar-se com o aluno fora da escola; oferecer grupos aos pais; respeitar os alunos e os familiares; oferecer orientações aos familiares. Por sua vez, os grupos dos profissionais levantaram as seguintes categorias em relação aos comportamentos que eles esperavam das famílias: comunicar-se com profissionais; reconhecer o trabalho dos profissionais; confiar no trabalho desenvolvido; ser responsável pela educação do filho; acreditar no desenvolvimento do filho; manter expectativas adequadas; questionar os profissionais de modo adequado; garantir a freqüência do aluno à escola; visitar a escola; participar das atividades. Quanto à própria atuação foram encontradas as seguintes categorias: comunicar-se com familiares; demonstrar seriedade; ser sincero; ser imparcial; respeitar os alunos e os familiares; conhecer as características dos familiares e dos alunos; incentivar a participação dos familiares; reunir-se com familiares; mostrar aos familiares as atividades realizadas; ajudar os familiares a manter expectativas adequadas. Espera-se que o levantamento e a descrição das categorias possam nortear os profissionais que trabalham na escola e familiares de crianças com deficiência na busca do estabelecimento de uma parceria colaborativa efetiva e de sucesso. Palavras-chaves: educação especial; família; equipe multidisciplinar; relação famíliaescola; parceria colaborativa; crianças com deficiência.