No description available.

The aim of this study was to investigate whether daily handling in the form of tactile stimulation can ifluence behaviour of adult common voles (Microtus arvalis). The voles were tested in three types of behavioural experiments - Acoustic startle test, Open Field test (OFT), and Elevated Plus Maze test (EPM). No significant impact of handling on personality traits was detected.

Leniency Programmes have been introduced as a complementary measure in the enforcement of competition law in detecting cartels, on the basis that hard to find evidence will be provided by undertakings coming forward to confess, in exchange for immunity or reduction in fines. The advantages of leniency are deemed to be twofold, since evidence is thereby expected to be given voluntarily, and in turn it would save up the limited resources available to enforcement authorities, by reducing lengthy investigations in search of evidence. Therefore, the widely accepted view by regulators, economists, and lawyers alike is that leniency is by far the most effective method of detecting and deterring anticompetitive activities by undertakings. An 'undertaking' covers any entity engaged in an economic activity that offers goods or services in a given market. In the UK, Chapter I of the Competition Act 1998 governs prohibitions that fall within the category of cartels of which price-fixing, market or customer sharing, agreements to restrict production or supply, and bid-rigging are the most serious 'hard-core cartels'. This study evaluates the efficacy of the Leniency Programme in the enforcement of competition law applied in respect of cartel infringements based on cases decided by the UK's principal enforcement authority. Chapter I cases decided and published over a twelve-year period, since the Competition Act 1998 came into force, have been analysed in order to evaluate whether the leniency programme has been an incentive for colluders to apply for leniency. The results indicate that very few leniency applications were submitted voluntarily before an investigation was begun by the enforcement authority. Moreover, the detection rate of Chapter I cases on average has been very low over the twelve-year period, less than 2 cases per year, excluding settlements. The research also shows that contrary to the accepted view that evidence relating to cartels is difficult to find, cartels studied in this thesis have left a trail of both electronic, and other evidence that the authorities were able to seize. Further, the leniency applicants were not always reliable witnesses, and despite leniency, the enforcement authorities had to conduct lengthy investigations, negating the cost saving assertion and taking resources away from ex officio interventions by the authorities. The conclusion drawn from this study is that rather than enhancing detection and deterrence of anticompetitive behaviour by undertakings, the leniency programme overlaps, and in effect, undermines the public enforcement of competition law in the UK.

Optimal Foraging Theory (OFT) has its origin in processualistic ideas in 1960s with traces back to the dawn of the archaeological science in the 19th century. The OFT model is based on the construction of an individual’s food item selection understood as an evolutionary construct that maximizes the net energy gained per unit feeding time. The most common variants are diet patch choice, diet breadth/prey choice models and Marginal Value Theorem (MVT). The theory introduced experimental studies combined with mathematically data analyses and computer simulations. The results visualized in the experimental diagrammed curve are possible to compare with the archaeological records. What is “optimal” is an empirical question not possible to know but still useful as a benchmark for measuring culture. The theory is common in USA but still not in Europe. OFT seems to be useful in hunter-gatherer research looking at human decisions, energy flow, depression of resources and extinction. This literature review concludes that the prey-choice/diet-breadth model seems to be useful for hunter-gatherer research on Gotland focusing on possible causes of the hiatus in archaeological records between 5000-4500 BC. / Optimal Foraging Theory (OFT) har sitt ursprung i de processualistiska ideérna under 1960-talet med spår tillbaka till arkeologins början som vetenskap under 1800-talet. OFT modellen baseras på konstruktionen av en individs födoämnesval som förstås som en evolutionär konstruktion som maximerar nettoenergiintaget per tidsenhet som gått åt för försörjningen. De vanligaste varianterna är patch-choice, diet breadth/prey choice modellerna och Marginal Value Theorem (MVT). Experimentella studier genomförs och data bearbetas matematiskt och visar datorsimulerade kurvdiagram möjliga att jämföra med arkeologiska källmaterial. Vad som är ”optimalt” är en empirisk fråga omöjlig att veta men användbar ändå som en slag referens för att mäta kultur. Teorin är vanlig i USA men ännu inte i Europa. OFT förefaller användbar inom forskning av jägare-samlare om man fokuserar på beslutsfattande, energiflöde, depression av resurser och utrotning av arter. Slutsatsen i denna litteraturöversikt är att prey choice/diet breadth modellen tycks vara användbar för gotländsk jägare-samlare-forskning som fokuserar på möjliga orsaker till de arkeologiska fyndens hiatus mellan 5000-4500 BC.

The Optimal Foraging Theory, rooted in the processual archaeology, uses a measuring methodology where the foraging strategy that gives the highest payoff measured as the highest ratio of energy gain per time unit is analysed (Mac Arthur & Pianca 1966, Emlen 1966). The theory is a branch of evolutionary ecology why much attention is paid to the interdependence of humans and preys and environmental conditions caused by climatologically and geographical changes or by overexploitation or other changes caused by humans. The analysis of Early Mesolithic pioneers onGotland, who settle in a transforming landscape, leaves indications of a Maglemose culture origin, probably from flooded original settlements in the south/southwest Baltic basin. The pioneers have to adapt to a seal-hunting economy dominated by grey seal which give the best cost-benefit outcome as big terrestrial mammals are missing and only mountain hare is available. The diet is narrow and there is a great risk for deficiency diseases as well as for acquiring hypervitaminosis and osteoporosis caused by excess of seal food. There is a hiatus c. 5000-4500 BC in the archaeological records on Gotland and the south-western Baltic region, and the master thesis hypothesises that Littorina Transgression I with a severe cold dip called the “8.2 ka BP cold event” has a delayed, but such a severe impact also on fauna and flora on Gotland, that the ecological system is destroyed. The possibility for humans to survive in a sustainable society is questionable. The extremely cold winters during this c. 400 years cold event, with glaciers moving southwards, delayed the blooming season, diminished the harvest and changed both flora and fauna. When the ecological niche for the grey seal is destroyed with flooded beaches close to the pioneers, human overexploitation is reinforced. With a diminishing population of mountain hare, which eventually gets extinct at the end of the Mesolithic, there are no alternatives but some birds and fish, hard to catch. Probably the pioneers abandon Gotland or move to a higher level on Gotland but no records are yet found why the period is called a hiatus. Extinction is the worst scenario or survival in such a small number that a sustainable society is lost. If so, new population groups repopulatedGotlandafter the Littorina transgressions. The origin is still unknown of the Pitted-ware and Funnelbeaker cultures that are populating Gotland after the transgressions. This master thesis can not confirm an affluent life style but rather a suffering starving society flooded by Littorina transgressions and struggling with the severe cold, caused by the “8.2 ka cold event” that makes the environmental conditions even worse. The subsistence economy is successively destroyed which probably causes the hiatus in archaeological records. The Littorina Transgression I with the “8.2 cold event” and the lack of terrestrial big animals are bottle necks. / Optimal Foraging Theory, med sina rötter i den processuella arkeologin, använder en metodik utgående från mätningar där insamlingsstrategin som ger den högsta avkastningen per tidsenhet analyseras (Mac Arthur & Pianca 1966, Emlen 1966). Teorin är en undergrupp inom den evolutionära ekologin och därför ägnas stor tid åt att uppmärksamma det ömsesidiga beroendet och påverkan som sker i miljön p.g.a. klimatologiska och geologiska orsaker men också p.g.a. mänsklig påverkan som exempelvis överförbrukning.  Analysen av tidigmesolitiska pionjärbosättare på Gotland, som möter ett landskap i förvandling, lämnar spår efter sig som tyder på ett ursprung i Maglemosekulturen i södra/sydvästra Östersjöregionen. De tvingas bli adapterade till en säljägarekonomi dominerad av gråsäl som ger det bästa energiutbytet, eftersom stora landdäggdjur saknas och endast bergshare finns tillgänglig. Dietvalet är smalt och det föreligger stor risk för både bristsjukdomar och A-vitaminförgiftning och osteoporos p.g.a. överkonsumtion av sälprodukter. Det finns ett uppehåll i de arkeologiska fynden c. 5000-4500 BC på Gotland liksom i södra Östersjöområdet. Magisteruppsatsens hypotes är att den kalla perioden med temperatursänkning som kallas ”8.2 ka BP cold event” under Littorinatransgression I har en fördröjd men så kraftigt övergripande effekt, på både djur- och växtliv på Gotland, att den förstör det ekologiska systemet och därmed möjligheten för människor att överleva i ett hållbart samhälle. De mycket hårda vintrarna under de c. 400 årens ”cold event” medför att glaciärerna dras sig söderut, blomningssäsongen fördröjs, skörden minskar och både fauna och flora förändras. När den ekologiska nischen för gråsälen förstörs av översvämmade stränder nära bosättarna förstärks överexploateringen, och då det inte finns någon alternativ föda utom en minskande harstam, svårfångade fåglar och fiskar, blir situationen fatal för de tidigmesolitiska bosättarna. Troligtvis flyttar de till andra platser inom Östersjönätverket eller till en högre nivå på Gotland, men fynd saknas hittills varför detta tomrum benämns ”hiatus”. Det värsta scenariot är att bosättarna dör ut eller överlever i ett så litet antal att det hållbara samhället går under.Om så är fallet återbefokas Gotland av gropkeramisk kultur och trattbägarkultur i anslutning till Littorinatrasgressionernas slut. Denna magisteruppsats kan inte konfirmera en livsstil i överflöd, utan snarare ett lidande svältande samhälle som översvämmas av Littorinatransgressioner med miljömässiga förhållanden som förvärras av den allvarliga kylan orsakad av ”8.2 ka cold event”.  Försörjningsmöjligheterna förstörs succesivt och befolkningen försvinner vilket troligen orsakar ett hiatus i de arkeologiska fynden. Littorina Transgression I med ”8.2 ka cold event” och bristen på stora landdjur är stora flaskhalsar.

Made available in DSpace on 2014-12-17T14:13:44Z (GMT). No. of bitstreams: 1 WaltecaLLS.pdf: 496999 bytes, checksum: 0f86df4fe320a7189a5b69ba52a5056e (MD5) Previous issue date: 2009-12-17 / Universidade Federal do Rio Grande do Norte / As infec??es f?ngicas oculares est?o sendo reconhecidas em todo o mundo como uma importante causa de morbidade e cegueira. A baixa biodisponibilidade dos f?rmacos como a anfotericina B, antif?ngico bastante utilizado no tratamento destas infec??es, nos tecidos posteriores dos olhos aliada ?s barreiras anat?micas oculares, que s?o capazes de limitar a sua absor??o e associado ao grave risco de desenvolvimento de rea??es adversas levam, geralmente, a um insucesso no tratamento desejado e a s?rias conseq??ncias para os pacientes acometidos. Pesquisadores em todo o mundo est?o buscando novas alternativas para contornar esta problem?tica e uma das principais linhas de pesquisa estabelecidas consiste no desenvolvimento de novas formula??es que visam melhorar a biodisponibilidade e reduzir a toxicidade associada ? aplica??o da anfotericina B. As microemuls?es surgem como novos sistemas capazes de carrear este f?rmaco para uso oftalmol?gico. O presente estudo objetivou a obten??o de uma microemuls?o biocompat?vel com a via de administra??o ocular contendo anfotericina B a fim de se estabelecer uma nova forma farmac?utica vi?vel para a administra??o t?pica nos olhos. O sistema obtido demonstrou, por meio dos estudos de caracteriza??o realizados, biocompatibilidade com a via de administra??o pretendida e surge, portanto, como uma nova e interessante apresenta??o farmac?utica contendo anfotericina B para ser utilizada, no futuro, no tratamento de infec??es f?ngicas oculares

Handreichung für Lehrer der Sekundarstufe II zur Einführung in das Wissenschaftliche Arbeiten (mit Materialien). Grundlage der Handreichung ist ein interdisziplinäres Projekt, das sich mit der Rezeption des Mittelalters in der Stadt Chemnitz auseinandergesetzt hat. In diesem Rahmen sind Komplexe Lernleistungen und Besondere Lernleistungen entstanden.

The internationalisation of conflicts has made the study of the effects of external support a prominent subfield within peace and conflict studies. How supporting states affect conflict strategies and changes the conflict dynamic has been the prime concern of this thesis. I have argued that when a government actor is supported by an external state with high soft power, in the form of political and economic capital, the government is less inclined to use one-sided violence as a conflict strategy. By using the principal- agent theory as a model to explain the relationship between the supporter and the supported state, I have found support for my argument. The government of the Central African Republic has conducted low levels of one-sided violence when supported by the soft power France. The government of South Sudan, on the other hand, has conducted high levels of one-sided violence when supported by the non-soft power Uganda. By coming to this conclusion, this paper has introduced soft power as an important concept in peace and conflict studies while also helping to elucidate the role of external supporters in conflict strategies. Future research should develop on the findings in this thesis by controlling for other possible explanations to why one-sided violence decreases depending on the characteristics of the support and include a greater number of cases.

Handreichung für Lehrer der Sekundarstufe II zur Einführung in das Wissenschaftliche Arbeiten (mit Materialien). Grundlage der Handreichung ist ein interdisziplinäres Projekt, das sich mit der Rezeption des Mittelalters in der Stadt Chemnitz auseinandergesetzt hat. In diesem Rahmen sind Komplexe Lernleistungen und Besondere Lernleistungen entstanden.

No description available.