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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
91

Efficiency and Social Capital in Micro, Small and Medium Enterprises: the Case of Ethiopia.

Worku, Eshetu Bekele. January 2008 (has links)
<p>This study extends the existing literature on how social networks enhance the performance and sustainability of small enterprises. More specifically, the study isolates and investigates the mechanisms through which social capital helps with the growth and survival of MSMEs. The evidence presented in this study strongly suggests that an indigenous social network widely practiced in Ethiopia, the &ldquo / iqqub&rdquo / , contributes significantly to the start-up, survival and development of urban MSMEs.</p>
92

Treatment Comparison in Biomedical Studies Using Survival Function

Zhao, Meng 03 May 2011 (has links)
In the dissertation, we study the statistical evaluation of treatment comparisons by evaluating the relative comparison of survival experiences between two treatment groups. We construct confidence interval and simultaneous confidence bands for the ratio and odds ratio of two survival functions through both parametric and nonparametric approaches.We first construct empirical likelihood confidence interval and simultaneous confidence bands for the odds ratio of two survival functions to address small sample efficacy and sufficiency. The empirical log-likelihood ratio is developed, and the corresponding asymptotic distribution is derived. Simulation studies show that the proposed empirical likelihood band has outperformed the normal approximation band in small sample size cases in the sense that it yields closer coverage probabilities to chosen nominal levels.Furthermore, in order to incorporate prognostic factors for the adjustment of survival functions in the comparison, we construct simultaneous confidence bands for the ratio and odds ratio of survival functions based on both the Cox model and the additive risk model. We develop simultaneous confidence bands by approximating the limiting distribution of cumulative hazard functions by zero-mean Gaussian processes whose distributions can be generated through Monte Carlo simulations. Simulation studies are conducted to evaluate the performance for proposed models. Real applications on published clinical trial data sets are also studied for further illustration purposes.In the end, the population attributable fraction function is studied to measure the impact of risk factors on disease incidence in the population. We develop semiparametric estimation of attributable fraction functions for cohort studies with potentially censored event time under the additive risk model.
93

Kurzové sázky jako jedna z forem patologického hráčství u adolescentů / Odds betting as a form of pathologic gambling among adolescents

DOKULIL, Ondřej January 2016 (has links)
The diploma thesis focuses on fixed-odds betting among male adolescents. In theoretical part, game as a whole life matter is explained, afterwards it aims closer to hazard game, especially fixed-odds betting. Regarding to children, multiple smaller studies, focused on risky behaviour on the internet and gambling, are introduced. Empirical part combines qualitative and quantitative approach. Interviews with betters jointly with the theory creates the base for hypothesises and questionnaire, which was distributed in five schools; three elementary and two high schools. Results of the empirical part are suggesting that adolescent boys have experiences with fixed-odds betting even though they are not of age. Frequently, the reason for betting is being involved in sport and the favourite form is on-line betting.
94

Frequência de anticorpos anti-Toxocara spp em escolares do município de Fernandópolis- SP, Brasil e análise da contaminação do solo por ovos do parasito / Frequency of anti-Toxocara spp antibody in school children from Fernandópolis-SP, Brazil and analysis of soil contamination by parasite eggs

Alex Jones Flores Cassenote 20 October 2010 (has links)
A toxocaríase é uma zoonose muito difundida em todo o mundo. Trata-se da infecção humana, em especial pelas larvas de Toxocara canis, um nematóide comum de cães. O objetivo do presente estudo foi levantar a soropositividade a anticorpos anti-Toxocara spp, identificar os fatores de risco em grupos de escolares da cidade de Fernandópolis/SP e avaliar a contaminação do solo por ovos desse e de outros geo-helmintos entre os anos de 2007 e 2008. Foi realizado um estudo transversal utilizando-se amostragem complexa e estratificada, por renda, para a avaliação da toxocaríase humana. O método diagnóstico empregado foi o teste de ELISA para detecção de anticorpos IgG anti-Toxocara spp. O estudo da contaminação do solo deu-se por meio da avaliação de amostras de solo de praças, parques públicos e escolas municipais e pela avaliação de amostras de fezes provenientes de 10 praças públicas. Foram avaliados 252 indivíduos em dois estratos, o primeiro representando baixa renda com 120 (47,6%) crianças e o segundo com 132 (52,4%) representando renda elevada. A frequência geral de positividade ao antígeno TES foi de 15,4% (39), sendo 28,3% (34) para o primeiro estrato contra 3,7% (5) do segundo (p<0,000). A exposição à geofagia (exposto OR ajustado 14,65 - IC95% = 2,14 a 89,25 e muito expostos OR ajustado 19,15 a IC95% = 2,96 a 123,94), o hábito de levar objetos à boca (exposto OR ajustado 9,31 - IC95% = 1,63 a 53,03 e muito expostos OR ajustado 42,29 a IC95% = 5,49 a 326,01) e a presença de mais de dois cães em domicílio (OR ajustado 21,25 = 1,7 a 264,87) foram variáveis associadas à positividade. O hábito de lavar as mãos antes das refeições (OR ajustado 0,01 - IC95% 0,00 a 0,05) representou importante fator de proteção. Foram avaliadas 225 amostras de solo, sendo 71% (160) provenientes de praças e parques públicos e 29% (65), de escolas municipais. Foi observado alto grau de contaminação de praças e parques públicos 28,4% (64), ao passo que nas escolas a positividade foi de 1,7% (6). Os parasitos encontrados com maior frequência foram de Toxocara spp 79,6% (47), Trichuris spp 13,5% (8) e ancilostomídeo 6,4% (4). Foram avaliadas ainda 400 amostras de fezes de cães, e observou-se uma positividade de 23,7% (95). Os parasitos observados com maior frequência nas amostras positivas foram ancilostomídeo símile 74,7% (71) e Toxocara canis, 53,6% (51). A positividade a anticorpos anti-Toxocara spp em indivíduos de 1 a 12 anos de idade, provenientes de cinco escolas do município de Fernandópolis/SP, foi relativamente baixa. Os principais fatores de risco/proteção dizem respeito às questões modificáveis como a geofagia, o hábito de levar objetos à boca, a existência de mais de dois cães em domicílio e o hábito de lavar as mãos antes das refeições. Os solos de praças e parques públicos de Fernandópolis/SP e amostras de fezes recolhidas em ambiente estavam altamente contaminados com geo-helmintos zoonóticos e representam fonte de infecção relevante para a população / Toxocariasis is a zoonosis of worldwide occurrence. It is defined as the human infection by larvae of nematodes, especially Toxocara canis, common intestinal parasite of dogs. The aim of this study was to estimate the frequency of anti-Toxocara spp antibodies, identify risk factors in groups of school children from the city of Fernandópolis/SP and evaluate soil contamination by eggs of this and other geohelminths between 2007 and 2008. It was conducted a cross-sectional study using complex sampling for the assessment of human toxocariasis. The diagnostic method used was the ELISA test for detection of IgG anti-Toxocara spp antibodies. The study of soil contamination was done through evaluation of soil samples from public places, sand boxes of municipal schools and evaluation of dogs stool samples from 10 public places. Two hundred and fifty two children were evaluated in two strata, the first with 120 children (47.6%) from low income families and the second with 132 (52.4%) from high income ones. The overall frequency of antibodies anti-Toxocara spp was 15.4% (39), being 28.3% (34) for the first stratum compared with 3.7% (5) of the second (p <0.000). The exposure to geophagy (exposed: adjusted OR 14.65 - CI 95% = 2.14 to 89.25; very exposed: adjusted OR 19.15 - CI 95%= 2.96 to 123.94), the habit of rising objects up to the mouth (exposed: adjusted OR 9.31 1.63 to 53.03; very exposed: adjusted OR 42.29 - CI 95%= 5.49 to 326.01) and the presence of more than two dogs at home (adjusted OR 21.25 - 1.7 to 264.87) were variables associated with positivity. The habit of washing hands before meals (adjusted OR 0.01 - CI 95% = 0.00 to 0.05) represented an important protective factor. Were evaluated 225 samples of soil: 71% (160) from public places and 29% (65) of municipal schools. It was observed a high contamination of public places with 28.4% (64) being positive, while in school positivity was 1.7% (6). The most frequent parasites eggs found were Toxocara spp 79.6% (47), Trichuris spp 13.5% (8) and Ancylostomatidae 6.4% (4). They were also evaluated 400 fecal samples of dogs and observed a positivity of 23.7% (95). The most frequent parasites observed in positive samples were Ancylostoma simile 74.7% (71) and Toxocara canis 53.6% (51). The anti-Toxocara spp antibodies positivity in school children from Fernandópolis/SP was relatively low. The main factors of risk/protection concern to modifiable issues like geophagy, the habit of rising objects up to the mouth, the existence of more than two dogs at home and the habit of washing hands before meals. The soil of public places of Fernandópolis/SP and feces samples collected from the environment were highly contaminated with zoonotic helminths and represent important source of infection for the population
95

Chronic myeloid leukemia and cancer

Gunnarsson, Niklas January 2017 (has links)
Background Chronic myeloid leukemia (CML) is a relatively rare hematological malignancy with a constant incidence of approximately 90 new cases each year in Sweden (0.9 cases/100 000 inhabitants). The etiology is largely unknown but high doses of ionizing radiation are a known but rare risk factor. The treatment options were for a long time limited to chemotherapies i.e. hydroxyurea and busulfan, interferon’s and allogeneic hematopoietic stem cell transplantation and the median survival were only about four years. Since the beginning of the 21st century a new way of treating CML has been introduced, the tyrosine kinase inhibitors (TKI), leading to a rapid decrease in leukemic cells and symptoms. Due to the TKIs, the overall 5-year survival is nowadays approximately 85 % and CML patients have time to develop other diseases, including other malignancies. The aims of this thesis was to investigate the present and future prevalence of CML and the prevalence of other malignancies prior and subsequent to the diagnosis of CML, malignancies among first-degree relatives of persons with CML. In addition, the incidence of autoimmune and chronic inflammatory diseases among patients with CML was also investigated.   Methods From the Swedish CML register, data over nearly all Swedish CML patients from 2002 and forward were obtained for paper II-IV. For paper I, the Swedish cancer register was used to identify all Swedish CML patients since 1970 and the Swedish cause of death register was used to identify an eventual date of death for these patients. With a constant incidence and the relative survival rates for CML patients between 2006 and 2012 as a model, the present and future prevalence was calculated. For paper II-IV, data from the Swedish cancer register was used to identify other malignancies than CML. For paper II, information about autoimmune and chronic inflammatory diseases was retrieved from the Swedish national patient register. For paper II and IV, five controls matched for year of birth, gender and county of residence were randomly selected from the Swedish register of the total population. To calculate odds ratio (OR), conditional logistic regression was used. To calculate the risk of a second malignancy for paper III, Standardized incidence ratio (SIR) was used. In paper IV, first-degree relatives (parents, siblings and offsprings) for both cases and controls were retrieved from the Swedish multi-Generation Register, where persons born later than 1932 and registered in Sweden at some time since 1961 are registered.   Results Prevalence and survival As shown in paper I, the 5-year overall survival for CML patients increased remarkably from 0.18 to 0.82 between 1970 and 2012. The prevalence increased from 3.9 to 11.9 per 100 000 inhabitants in Sweden between 1985 and 2012. By assuming no further improvements in relative survival as compared to the survival rates between 2006 and 2012, the prevalence by 2060 is expected to increase to 22.0 per 100 000 inhabitants. This corresponds to 2 587 CML patients as compared to 1 137 CML patients in 2012.   Malignancies, autoimmune and chronic inflammatory diseases prior to CML In study II, more than 45 000 person-years of follow-up were evaluated in 984 CML patients diagnosed between 2002 and 2012. With an OR of 1.47 (95 % CI 1.20–1.82) and 1.55 (95 % CI 1.21–1.98), respectively, the prevalence of prior malignancies and autoimmune diseases were significantly increased as compared to matched controls. On the other hand, no association between CML and chronic inflammatory diseases was shown.   Second malignancies In 868 CML patients, diagnosed between 2002 and 2011, 52 malignancies were observed in the Swedish cancer register, as shown in paper III. When compared to expected rates in the background population, a significantly increased risk of second malignancies with a SIR of 1.52 (95 % CI 1.13–1.99) was shown. When looking at specific cancer types, gastrointestinal as well as nose and throat cancer were significantly increased.   Familial aggregation of malignancies 984 CML patients were identified in paper IV. However, 184 had a birth date prior to 1932, subsequently only 800 patients were analyzed. Among them, 4 287 first-degree relatives were identified, compared to 20 930 first-degree relatives of the matched controls. 611 malignancies were retrieved; no significant increase of malignancies in first-degree relatives of CML patients was shown (OR 1.06; 95 % CI: 0.96–1.16).   Conclusion Since CML patients nowadays have a high survival rate, the calculations in this thesis shows that the prevalence of CML will almost double by 2060. CML patients have an increased risk of developing malignancies prior and subsequent to the diagnosis of CML, suggesting a hereditary or acquired predisposition to develop cancer. Since there is no familial aggregation of malignancies in CML patients, a hereditary predisposition to develop cancer is unlikely to be part of the pathogenesis of CML, leaving an acquired predisposition more likely.
96

Efficiency and social capital in Micro, Small and Medium Enterprises: the case of Ethiopia

Worku, Eshetu Bekele January 2008 (has links)
Philosophiae Doctor - PhD / This study extends the existing literature on how social networks enhance the performance and sustainability of small enterprises. More specifically, the study isolates and investigates the mechanisms through which social capital helps with the growth and survival of MSMEs. The evidence presented in this study strongly suggests that an indigenous social network widely practiced in Ethiopia, the "iqqub", contributes significantly to the start-up, survival and development of urban MSMEs. / South Africa
97

Patterns of household level availability, accessibility and utilisation of food in some rural areas of Sekhukhune District in South Africa

Masekoameng, Mosima R. 15 February 2016 (has links)
Institute for Rural Development / PhDRDV
98

A Content Originality Analysis of HRD Focused Dissertations and Published Academic Articles using TurnItIn Plagiarism Detection Software

Mayes, Robin James 05 1900 (has links)
This empirical exploratory study quantitatively analyzed content similarity indices (potential plagiarism) from a corpus consisting of 360 dissertations and 360 published articles. The population was defined using the filtering search criteria human resource development, training and development, organizational development, career development, or HRD. This study described in detail the process of collecting content similarity analysis (CSA) metadata using Turnitin software (www.turnitin.com). This researcher conducted robust descriptive statistics, a Wilcoxon signed-rank statistic between the similarity indices before and after false positives were excluded, and a multinomial logistic regression analysis to predict levels of plagiarism for the dissertations and the published articles. The corpus of dissertations had an adjusted rate of document similarity (potential plagiarism) of M = 9%, (SD = 6%) with 88.1% of the dissertations in the low level of plagiarism, 9.7% in the high and 2.2% in the excessive group. The corpus of published articles had an adjusted rate of document similarity (potential plagiarism) of M = 11%, (SD = 10%) with 79.2% of the published articles in the low level of plagiarism, 12.8% in the high and 8.1% in the excessive group. Most of the difference between the dissertations and published articles were attributed to plagiarism-of-self issues which were absent in the dissertations. Statistics were also conducted which returned a statistically significant justification for employing the investigative process of removing false positives, thereby adjusting the Turnitin results. This study also found two independent variables (reference and word counts) that predicted dissertation membership in the high (.15-.24) and excessive level (.25-1.00) of plagiarism and published article membership in the excessive level (.25-1.00) of plagiarism. I used multinomial logistic regression to establish the optimal prediction model. The multinomial logistic regression results for the dissertations returned a Nagelkerke pseudo R2 of .169 and for the published articles a Nagelkerke pseudo R2 .095.
99

Models for Additive and Sufficient Cause Interaction

Berglund, Daniel January 2019 (has links)
The aim of this thesis is to develop and explore models in, and related to, the sufficient cause framework, and additive interaction. Additive interaction is closely connected with public health interventions and can be used to make inferences about the sufficient causes in order to find the mechanisms behind an outcome, for instance a disease. In paper A we extend the additive interaction, and interventions, to include continuous exposures. We show that there does not exist a model that does not lead to inconsistent conclusions about the interaction. The sufficient cause framework can also be expressed using Boolean functions, which is expanded upon in paper B. In this paper we define a new model based on the multifactor potential outcome model (MFPO) and independence of causal influence models (ICI). In paper C we discuss the modeling and estimation of additive interaction in relation to if the exposures are harmful or protective conditioned on some other exposure. If there is uncertainty about the effects direction there can be errors in the testing of the interaction effect. / Målet med denna avhandling är att utveckla, och utforska modeller i det så kallade sufficent cause ramverket, och additiv interaktion. Additiv interaktion är nära kopplat till interventioner inom epidemiology och sociologi, men kan också användas för statistiska tester för sufficient causes för att förstå mekanimser bakom ett utfall, tex en sjukdom. I artikel A så expanderar vi modellen för additiv interaktion och interventioner till att också inkludera kontinuerliga variabler. Vi visar att det inte finns någon modell som inte leder till motsägelser i slutsatsen om interaktionen. Sufficient cause ramverket kan också utryckas via Boolska funktioner, vilket byggs vidare på i artikel B. I den artikeln definerar vi en modell baserad på mutltifactor potential outcome modellen (MFPO) och independence of causal influence modellen (ICI). I artikel C diskuterar vi modelleringen och estimering av additiv interaktion i relation till om variablerna har skadlig eller skyddande effekt betingat på någon annan variabel. Om det finns osäkerhet kring en effekts riktning så kan det leda till fel i testerna för den additiva interaktionen. / <p>Examinator: Professor Henrik Hult, Matematik, KTH</p>
100

Psychische Störungen bei Frauen in Abhängigkeit von Alter und Beruf: Sekundäranalytische Untersuchung aller weiblichen erwerbstätigen Versicherten der AOK PLUS des Zeitraums 2007-2011

Kaufmann, Juliane 21 July 2020 (has links)
Das Hauptanliegen dieser Arbeit besteht in der Erweiterung des Kenntnisstandes zur Bedeutung des Berufs im Hinblick auf Prävalenz bzw. Risiko einer Psychischen und Verhaltensstörung (PVS) bei Frauen. Es gibt zahlreiche deskriptive Aussagen von Krankenkassen zum Auftreten verschiedener Diagnosegruppen oder Einzeldiagnosen, die sich bezüglich der Berufe jedoch auf die Gesamtheit der PVS beschränken. Die Analysen im Rahmen dieser Arbeit beruhen auf den Daten der weiblichen Versicherten der AOK PLUS für die Jahre 2007 bis 2011 mit insgesamt 2.113.083 Versichertenjahren. Es werden inferenzstatistische Aussagen getroffen, die auf Ergebnissen explorativer Voranalysen beruhen. Den berufsbezogenen Analysen werden zunächst Auswertungen zum Alter vorangestellt (Abschnitt 4). Erwartungsgemäß sind die Unterschiede zwischen den Altersgruppen für jede betrachtete Diagnosegruppe signifikant, jedoch weisen die Diagnosegruppen nicht dieselbe Altersabhängigkeit auf. Mit zunehmendem Alter zeigen sich zudem längere Erkrankungsdauern. Die Berufe im Datenbestand der AOK PLUS sind mittels der Klassifikation KldB 1988 [1] codiert (ca. 330 3-Steller). Für die berufsbezogenen Analysen wird in Abschnitt 5 zunächst die Frage geklärt, ob sich mittels Aggregationen der 3-Steller eine geeignetere Systematik finden lässt. Bis auf die Zusammenfassung einiger weniger 3-Steller ist das nicht der Fall. Basierend auf diesen Ergebnissen wird in Abschnitt 6 ein zweistufiges Vorgehen gewählt. In einem ersten Schritt werden für jede betrachtete PVS-Diagnose (bzw. Diagnosegruppe) die 21 Berufe mit den größten Quoten (AU-Personen pro 1.000 Versichertenjahre) ermittelt. Dabei werden zusätzlich altersstandardisierte Quoten berechnet. In einem zweiten Schritt werden die Ergebnisse des ersten Schrittes mittels Binärer Logistischer Regression (BLR) mathematisch-statistisch abgesichert. Dabei wird die Gesamtheit der nicht ausgewählten Berufe (also alle außer den 21) als Referenzgruppe verwendet. Für alle 21 ausgewählten Berufe werden dann die Odds Ratios gegenüber der Referenzgruppe in Verbindung mit einer Aussage zur Signifikanz ermittelt. Daraus resultiert schließlich eine Rangreihe der „Risikoberufe“, sortiert nach den unteren Grenzen der Konfidenzintervalle. Das Alter wird in diesem Schritt durch Einbezug als potentielle Einflussgröße berücksichtigt. Die Ergebnisse (Abschnitte 6 und 7) zeigen, dass Frauen besonders von PVS betroffen sind, wenn sie als Schienenfahrzeugführer (711), Soldaten, Grenzschützer, Polizisten, Sicherheitskontrolleure (801, 803), Krankenversicherungsfachleute (693), Telefonisten (734) sowie als Fachschul-, Berufsschul- und Werklehrer (874) arbeiten. Für Einzeldiagnosen und Diagnosegruppen ergibt sich ebenfalls ein differenziertes Bild. Bei den Erkrankungsdauern in Abhängigkeit vom Beruf zeigen sich keine substantiellen Auffälligkeiten.:1 Einleitung 7 2 Problemlage und Fragestellungen 8 2.1 LITERATURÜBERSICHT 8 2.1.1 Allgemeine Aussagen und Kosten 8 2.1.2 Aussagen zu Diagnosegruppen und Einzeldiagnosen der PVS 10 2.1.3 Aussagen zum Alter 12 2.1.4 Aussagen zum Beruf 13 2.1.5 Berufe als Risikofaktor für psychische Fehlbelastung 19 2.1.6 Psychischen Gesundheit von Frauen: Der Beruf als Modulator 21 2.1.7 Gesamteinschätzung zum Kenntnisstand 21 2.2 FRAGESTELLUNGEN 23 2.2.1 Zum Alter 24 2.2.2 Zur Systematik der Berufe 25 2.2.3 Zum Beruf 26 2.2.4 Zur Relation der Frage- und Zielstellungen 26 3 Datenbasis und methodische Aspekte 27 3.1 DATENBASIS 27 3.2 INDIKATOREN, DESKRIPTIVE STATISTIKEN 28 3.3 SYSTEMATIK DER BERUFE 29 3.4 MATHEMATISCH-STATISTISCHE VERFAHREN 30 3.4.1 Altersstandardisierung 30 3.4.2 Chi-Quadrat- und MANTEL-HAENSZEL-Test 31 3.4.3 Binäre Logistische Regression (BLR) 31 3.4.4 Mathematisch-statistische Aussagen zu Erkrankungsdauern 33 3.4.5 Signifikanzniveau und Darstellung von Signifikanzaussagen 35 4 F-Diagnosen und Z73 nach Alter 36 4.1 BETROFFENENQUOTEN 36 4.2 ERKRANKUNGSDAUERN 39 5 Systematiken zum Beruf im Vergleich 43 5.1 BERUFSORDNUNG 44 5.2 SYSTEMATIK NACH BLOSSFELD 45 5.3 ZUSAMMENGEFASSTE BERUFSGRUPPEN NACH SUGA 46 5.4 BERUFSGRUPPEN 47 5.5 PARTIELL AGGREGIERTE BERUFE 48 6 F-Diagnosen und Z73 nach Beruf und Alter 49 6.1 DIAGNOSEHAUPTGRUPPE F00-99 PSYCHISCHE UND VERHALTENSSTÖRUNGEN 49 6.1.1 AU-Personen 49 6.1.2 Erkrankungsdauern 54 6.2 DIAGNOSEGRUPPEN IM VERGLEICH 55 6.3 DIAGNOSEGRUPPE F10-19 PSYCHISCHE UND VERHALTENSSTÖRUNGEN DURCH PSYCHOTROPE SUBSTANZEN 56 6.3.1 Gesamtgruppe F10-19 – AU-Personen 56 6.3.2 Diagnosen F10 und F17 – AU-Personen 59 6.3.3 AU-Personen – die auffälligsten Berufe 60 6.3.4 Erkrankungsdauern 61 6.4 DIAGNOSEGRUPPE F30-39 AFFEKTIVE STÖRUNGEN 62 6.4.1 Gesamtgruppe F30-39 – AU-Personen 62 6.4.2 Diagnosen F32 und F33 – AU-Personen 64 6.4.3 AU-Personen – die auffälligsten Berufe 66 6.4.4 Erkrankungsdauern 66 6.5 DIAGNOSEGRUPPE F40-48 NEUROTISCHE, BELASTUNGS- UND SOMATOFORME STÖRUNGEN 68 6.5.1 Gesamtgruppe F40-48 – AU-Personen 68 6.5.2 Diagnosen F41, F43, F45, F48 – AU-Personen 70 6.5.3 AU-Personen – die auffälligsten Berufe 73 6.5.4 Erkrankungsdauern 74 6.6 DIAGNOSE Z73 PROBLEME BEI DER LEBENSBEWÄLTIGUNG (BURN-OUT) 75 6.6.1 AU-Personen 75 6.6.2 Erkrankungsdauern 76 6.7 AU-PERSONEN – DIE AUFFÄLLIGSTEN BERUFE IM GESAMTKONTEXT 77 7 Diskussion der Ergebnisse 83 7.1 METHODISCHE ASPEKTE 83 7.1.1 Einordnung der Analysen im Sinne der Epidemiologie 83 7.1.2 Bezugsbasis Versichertenjahre versus Versicherte 85 7.1.3 Zur Altersstandardisierung 86 7.1.4 Zur Binären Logistischen Regression 88 7.1.5 Binäre logistische Regression versus MANTEL-HAENSZEL Test und Anmerkungen zum Signifikanzniveau 89 7.1.6 Zur Auswahl der Zielgrößen AU-Personen und Erkrankungsdauern 89 7.2 INHALTLICHE ASPEKTE 91 7.2.1 Zum Alter 91 7.2.1.1 Betroffenenquoten 91 7.2.1.2 Erkrankungsdauern 92 7.2.2 Zu den Berufen 93 7.2.2.1 Zu F00-99 – Gesamtheit der PVS – Erkrankungsrisiko 93 7.2.2.2 Zu F00-99 – Gesamtheit der PVS – Erkrankungsdauern 98 7.2.2.3 Zu den Diagnosegruppen F30-39 Affektive Störungen und F40-48 Neurotische, Belastungs- und somatoforme Störungen – Erkrankungsrisiko 99 7.2.2.4 Zur Diagnose F10 PVS durch Alkohol – Erkrankungsrisiko 103 7.2.2.5 Zur Diagnose F17 – PVS durch Tabak 106 7.2.2.6 Zu Diagnose Z73 – Burn-out-Syndrom 108 7.2.3 Zusammenfassung 109 7.3 AUSBLICK 110 8 Literatur 112 9 Verzeichnis der Abkürzungen 122 10 Verzeichnis der Abbildungen 124 11 Verzeichnis der Tabellen 126 Anlagen 128

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