The current study assessed the effects of two teaching stimulus presentations, i.e. picture to word and word to word, used to teach second language vocabulary to college students. It also evaluated the emergence of untaught relations when picture to word and word to word were used separately as a teaching strategy. The findings showed picture to word training resulted in more untaught relations. Several aspects such time allotted for online quizzes, experimental and teaching arrangements and vocabulary complexity were suggested for future research.

In the US, the incidence and mortality rates of hepatocellular carcinoma (HCC) are alarmingly increasing since no effective therapy is available for the advanced disease. Activation of IGF signaling is a major oncogenic event in diverse cancers, including HCC. Insulin-like growth factor binding protein-7 (IGFBP7) inhibits IGF signaling by binding to IGF-1 receptor (IGF-1R) and functions as a potential tumor suppressor for hepatocellular carcinoma (HCC). IGFBP7 abrogates tumors by inducing cancer-specific senescence and apoptosis and inhibiting angiogenesis. We now document that Igfbp7 knockout (Igfbp7-/- ) mouse shows constitutive activation of IGF signaling, presents with pro-inflammatory and immunosuppressive microenvironment, and develops spontaneous tumors in lungs and liver and markedly accelerated carcinogen-induced HCC. Loss of Igfbp7 resulted in increased proliferation and decreased senescence in hepatocytes and mouse embryonic fibroblasts that could be blocked by an IGF-1 receptor inhibitor. A significant inhibition of genes regulating immune surveillance was observed in Igfbp7-/- livers which was associated with marked inhibition in antigen cross presentation by Igfbp7-/- dendritic cells. IGFBP7 overexpression inhibited growth of HCC cells in syngeneic immune competent mice, which could be abolished by depletion of CD4+ or CD8+ T lymphocytes. Our studies unravel modulation of immune response as a novel component of pleiotropic mechanisms by which IGFBP7 suppresses HCC. Even though HCC has an immunosuppressive milieu, immune targeted therapies are beginning to demonstrate significant objective responses in clinical trials. IGFBP7 might be an effective anti-HCC therapeutic by directly inhibiting cancer cells and stimulating an anti-tumor immune response.

Diploma thesis is focused on creation of educational materials supporting the education of biochemistry, specifically amino acids and proteins, at secondary level. At first the analysis of Czech chemistry textbooks concerning the two topics - amino acids and proteins was performed. The major problems found were related to the insufficient graphical representation of biomolecules, unsatisfactory motivational components and insufficient integration of the topic with biology or everyday life experience. The supporting educational materials, presented in this work, supplement the widely used chemistry textbooks. The materials includes a graphic oriented presentation, interactive animations demonstrating the process of denaturation and precipitating of proteins at macroscopic and molecular level, poster presenting the structural formulas of standard amino acids, 3D models of selected proteins, additional texts supporting the current topics concerning amino acids and proteins and the laboratory protocols for students. The presented support materials were evaluated at the secondary school conditions. They were tested in one class and the improvement of student's understanding of the topic was compared to the second class employing only the classical educational methods. The comparison of the results of...

The Master Thesis The depiction of events in Ukraine on photographs - ethical aspects of depicting conflict presents a case study focused on depiction of Ukrainian crisis in photographs during a defined period of time of 2014 in five Czech and five foreign newspapers. The first part of the thesis introduces the theoretical concepts that are the basis for the analysis. The analytical part presents the research of depiction of the Ukrainian events in news photographs in the daily newspapers using the technique of content picture analysis. The results let us compare the differences between the approach of the individual Czech and foreign newspapers to the issue of publishing graphic images of violence and its victims. Based on these findings, the thesis tries to define the contemporary trends regarding the ethical issues of photojournalism. Powered by TCPDF (www.tcpdf.org)

Cette étude porte sur les relations entretenues entre les modalités de mise en scène de soi au cours des interactions et le processus de construction identitaire individuel. Elle vise à comprendre pourquoi certains acteurs sont plus enclins que d’autres à conformer leurs attitudes aux individus et situations qu’ils sont amenés à rencontrer. Pour ce faire, nous avons eu recours à des méthodes qualitatives comme quantitatives. L’analyse de discours sur soi, fondée sur la lecture d’autobiographies et récits de vie, a permis de souligner la part active des individus dans le processus d’autoconstruction mis en œuvre. La diffusion d’un questionnaire permettant de mesurer leurs capacités à modeler leur face en fonction des injonctions externes (le monitorage de soi) ainsi que leurs particularités identitaires objectives (critères sociodémographiques) comme subjectives (conscience de soi et estime de soi) a révélé, grâce aux scores ainsi relevés et aux traitements de variables qui en ont découlé, toute l’importance des facteurs sociaux dans la définition des comportements individuels. Ainsi, pour comprendre les spécificités individuelles en termes de présentation de soi comme d’identité il importe tout autant d’éclairer les ancrages sociaux des acteurs que la façon dont ils les traitent, ceci afin d’approcher au plus près du phénomène de « subjectivation de l’objectif » qu’ils mettent en œuvre pour se singulariser. Fort de ce résultat, une troisième analyse porte plus particulièrement sur la période d’émergence de l’âge adulte (de 18 à 27 ans) qui est marquée par une rupture avec les injonctions normatives relatives à l’enfance et l’adolescence sans être parfaitement associée aux exigences de l’âge adulte. Cet âge de la vie, qui accorde plus de libertés aux individus en matière d’expérimentations (notamment dans les domaines des études, du travail et des relations), est associé aux scores les plus élevés en monitorage de soi. Ce résultat conduit à établir un parallèle entre les conditions de vie des individus et les modalités d’adaptation de leurs faces. Autrement dit, et pour ce qui concerne la portée générale de cette recherche doctorale, l’expérience de vie au quotidien constitue le facteur principal de la plus ou moins grande tendance des acteurs à adopter et présenter les attitudes qu’ils considèrent comme attendues d’eux. / This study focuses on relations between self-presentation modalities during interactions and individual identity construction process. It aims to understand why certain people are more disposed than other to conform their attitudes to individuals and situations they are led to meet. To do this, we resorted in both qualitative and quantitative methods. The analysis of self-speech based on reading autobiographies and narratives of life led to underline the active part of individuals in the autoconstruction process implemented. The broadcasting of a questionnaire to measure their abilities to shape their face in regard to external injunctions (self-monitoring) and their objective identity peculiarities (sociodemographic criteria) as subjective (self-consciousness and self-esteem) revealed, thanks to the scores thus raised and the treatment of variables that resulted, all the importance of social factors on the definition of individual behaviors. Then, to understand individual specificities in terms of self-presentation as identity, it is equally important to light social anchors of actors as much as how they treat them, in order to approach in closer of “subjectivation of objective” phenomenon they implement to singularize themselves. Considering this result, a third analysis focuses more particularly on the emerging adulthood period (from 18 to 27 years old), which is marked by a rupture with normative injunctions related to childhood and adolescence without being perfectly associated to adulthood requirements. This period of life, which allows more freedom to individuals in terms of experimentations (in particular in the fields of studies, work and relationships), is associated with the highest scores in self-monitoring. This result leads us to establish a parallel between living conditions of individuals and the modalities of adaptation of their faces. In other words, and about the general scope of this doctoral research, daily life experience constitutes the main factor of more or less big tendency of actors in adopting and present the attitudes they consider as expected from themselves.

This diploma thesis deals with the relationship of archaeology and the general public in Czech Republic. The aim of the thesis is firstly the analysis and consequent evaluation of the current situation in presentation of Czech archaeology and secondly, the proposition of possible solutions of this situation. The thesis contains the theoretical parts besides the practical ones, which present the point of view of both general public and experts, on the ground of realized research of public opinion. Some of the chapters contain also foreign analogies, that have to serve as means to deeper understanding and demonstration of broader comunication possibilities between archaeologist and the public. Key words: archaeology, science, general public, Czech Republic, popularization, presentation

This thesis deals with the relationship between media coverage of political parties and election results. Specifically, it focuses on four political parties (TOP 09, Věci veřejné, KDU- ČSL and Strana zelených) in the period of nine months before the parliamentary elections in May 2010. The two established political parties were not successful in these elections (KDU- ČSL and Strana zelených), the other two parties were. Using quantitative content analysis of media content this work examines media coverage of these four parties in nationwide television, radio and print media. The thesis compares differences between media presentations of the parties with the evolution of political preferences of the parties. As a source, monthly data acquired by two public opinion research agencies - CVVM and Median - was used. Even more important to answer the research questions was to compare the media presentation of the parties with their final election results. The thesis assumes that the form of media presentation of the parties is one of the factors that affects their voters' support. Based on the data found this thesis tries to find out trends and patterns guiding the relationship between media space which parties achieved, the development of their electoral preferences and the final election results.

Multimedia exploration is addressing the issue of searching within multimedia collections where the data is not annotated, the user is not able to formulate the text query, does not have any example data or wants to get quickly acquainted with the features of the collection. Part of the exploration is also the presentation of the results which is the main contribution of this thesis. The relations between the pictures in the exploration results are transformed into a graph which is visualised through a particle physics model. To visualize a large number of pictures, it is necessary to optimize the calculation. This thesis describes the optimization of both the basic algorithms and their adaptations for the need of multimedia exploration. The calculation layout is available in 2D and 3D space. Powered by TCPDF (www.tcpdf.org)

This thesis deals with archaeological tourism in the Ústí nad Labem region. Based on scientific literature, the general issues of archeology and tourism are analyzed. The result of this analysis points to the fact, that there are a lot of archaeological tourist destinations in this region. The most attractive ones are presented in this thesis in the form of a tour guide intended for the general public. An opinion poll was coducted as part of the thesis. Based on the poll we can assume that the general awareness of archeology and archaeological tourist destinations in the Ústí region is at an average level. It is safe to say that the public attitude towards archeology is generally positive. Czech castles are especially popular among the archaeological tourist destinations. The most convenient public presentation of archaeological sites is by using information boards with brief descriptions and vivid illustrations. The vast majority of interviewees indicated that they would welcome a higher degree of presentation of historical monuments in the Ústí nad Labem region - for example through a dedicated website. This thesis describes the advantages as well as the disadvantages of archaeological tourism abroad, which were used as a basis for proposals on how to improve the situation in the region. The...

Denna studie undersöker vilka budskap som Beyoncé konstruerar på sin Instagram genom enbart bildkommunikation. Då kända profiler har möjlighet att vara opinionsbildare för sina följare är det intressant att studera vilka budskap utöver deras huvudgenre, som de väljer att konstruera. Detta då det kan påverka människor som följer henne så att även de anammar dessa föreställningar, värderingar och handlingar. Eftersom Beyoncé har ett stort följeslag på sin Instagram och då hon själv publicerar bilderna är hon en representant för det här fenomenet, som är att gå utanför sin huvudgenre och vara en opinionsbildare. I studien använder vi oss av en kvalitativ innehållsanalys. Vi undersöker Beyoncés Instagram-profil, där vi sedan genom ett strategiskt urval väljer ut sju bilder. Därefter analyseras bilderna utifrån vårt teoretiska ramverk med utgångspunkt i semiotik, genus, rasism, självpresentation och klädernas betydelse. Detta ger en djupgående analys som besvarar studiens syfte och frågeställningar. Resultatet visar på att Beyoncé både direkt och indirekt konstruerar budskap genom enbart sin bildkommunikation. Det är bland annat budskap om politik, feminism och familjesituationer. Hon framställer även sociala roller som kommer till uttryck i bilderna. Dessa sociala roller är till exempel mamma, artist och karriärkvinna. / This study examines what messages Beyoncé construes on her Instagram through merely visual communication. It is interesting to study what messages celebrities convey through their visual communication that is outside their own main genre, considering they have the opportunity to be moulders of public opinion. This is because they have the ability to influence their followers so that they also adopt to these ideas, values and actions. Beyoncé is a representative for this phenomenon because she publishes her own pictures on Instagram and has a big number of followers. In this study, we use a qualitative content analysis. First, we examined Beyoncés Instagramaccount and then chose seven pictures with the help of a strategic selection. Thereafter we analyzed the pictures with the help of our theoretical framework based on the theories of semiotics, gender, rasicm, self-presentation and the meaning of clothes. This makes a contribution to a profound analysis that addresses the issue studied and the aim of the study. The results show that Beyoncé does construe messages, both directly and indirectly through her visual communication. Some of the messages she conveys are about politics, feminism and family situations. She also constructs social roles through her pictures. These are roles such as a mother, an artist and a businesswoman.