Yes

Yes

Yes

Sepsis is one of the leading causes of death in U.S. hospitals, resulting from organ dysfunction caused by an inappropriate inflammatory reaction to an infection. Timely treatment with empiric antibiotics in the emergency department is crucial to facilitate positive patient outcomes. The Surviving Sepsis Campaign (SSC) recommends initiating empiric antibiotic therapy within one hour of presentation to the emergency department. Some emergency departments have implemented sepsis management protocols to guide care and ensure timely treatment. The purpose of this study is to determine the effect of a formal sepsis protocol in the emergency department on the time to antibiotic administration. A literature review was conducted using CINAHL, Cochrane Database, Health Source: Nursing/Academic Edition, and MEDLINE. Results from one systematic review, eight quasi-experimental studies, and four quality improvement projects suggested that implementation of a sepsis management protocol in an emergency department may decrease the time to antibiotic administration. (< 10 = spell out) Eleven of the 13 articles reported decreased time to antibiotic administration by as much as 8-193 minutes compared to pre-protocol. One study met the SSC goal of 1 hour and reported a median administration time of 17 minutes. Time to antibiotics was influenced by protocols based on published sepsis guidelines, inclusion of antibiotic guidelines, nurse-initiated treatment, and education for emergency clinicians regarding sepsis management. Emergency departments should implement sepsis protocols adapted to their local institution to decrease time to antibiotic administration and reduce mortality of sepsis patients. Further research on how sepsis protocols affect antibiotic administration time is needed.

The MSU ERC UltraScope system consists of a distributed computing system, custom PCI cards, GPS receivers, and a re-radiation system. The UltraScope system allows precision timestamping of events in a distributed application on a system where the CPU and PCI clocks are phase-locked. The goal of this research is to expand the UltraScope system, using software routines and minimal hardware modifications, to allow precision timestamping of events on an asynchronous distributed system. The timestamp process is similar to the Network Time Protocol (NTP) in that it uses a series of timestamps to improve precision. As expected, the precision is less accurate on an asynchronous system than on a synchronous system. Results show that the precision is improved using this sequence of timestamps, and the major error component is due to operating system delays. The errors associated with this timestamping process are characterized using a synchronous system as a baseline.

No description available.

The Session Initiation Protocol (SIP) was first published in 1999, by the Internet Engineering Task Force (IETF), to be the standard for multimedia transfers. SIP is a peer-to-peer signaling protocol that is capable of initiating, modifying, and terminating media sessions. SIP utilizes existing Internet Protocols (IP) such as Domain Name Service (DNS) and the Session Description Protocol (SDP), allowing it to seamlessly integrate into existing IP networks. As SIP has matured and gained acceptance, its deficiencies when functioning as a multipoint communications protocol have become apparent. SIP currently supports two modes of operation referred to as conferencing and multicasting. Conferencing is the unicast transmission of session information between conference members. Multicasting uses IP multicast to distribute session information. This thesis proposes an extension for the Session Initiation Protocol that improves functionality for multipoint communications. When using conferencing, a SIP user-agent has limited information about the conference it is taking part in. This extension increases the awareness of a SIP node by providing it with complete conference membership information, the ability to detect neighboring node failures, and the ability to automatically repair conference partitions. Signaling for conferencing was defined and integrated into a standard SIP implementation where it was used to demonstrate the above capabilities. Using a prototype implementation, the additional functionality was shown to come at the cost of a modest increase in transaction message size and processing complexity. IP multicast has limited deployment in today's networks reducing the usability of this useful feature. Since IP multicast support is not guaranteed, the use of application layer multicast protocols is proposed to replace the use of IP multicast. An efficient means of negotiating an application layer protocol is proposed as well as the ability to provide the protocol with session information to begin operation. A ring protocol was defined and implemented using the proposed extension. Performance testing revealed that the application layer protocol had slightly higher processing complexity than conferencing, but on average had a smaller transaction message size. / Master of Science

Modern Printed Circuit Boards (PCB) contain sophisticated and valuable electronic components, and this makes them a prime target for counterfeiting. In this thesis, we consider a method to test if a PCB is genuine. One high-level solution is to use a secret identifier of the board, together with a cryptographic authentication protocol. We describe a mechanism that authenticates all major components of PCB as part of attesting the PCB. Our authentication protocol constructs the fingerprint of PCB by extracting hardware fingerprint from the components on PCB and cryptographically combining the fingerprints. Fingerprints from each component on PCB are developed using Physical Unclonable Functions (PUF). In this thesis, we present a PUF based authentication protocol for remote integrity checking using multiple PUF component level identifiers. We address the design on 3 different abstraction levels. 1)Hardware Level, 2)Hardware Integration level, 3)Protocol level. On the hardware level, we propose an approach to develop PUF from flash memory component on the device. At the hardware Integration level, we discuss a hardware solution for implementing a trustworthy PUF based authentication. We present a prototype of the PUF based authentication protocol on an FPGA board via network sockets. / Master of Science

The goal of this research is to improve the communications protocol for Dual Ring Power Electronics Systems called PESNet. The thesis will focus on making the protocol operate in a more reliable manner by tolerating Hardware Manager failures and allowing failover among duplicate Hardware Managers within PEBB-based systems. In order to make this possible, two new features must be added to PESNet: utilization of the secondary ring for fault-tolerant communication, and dynamic reconfiguration of the network. Many ideas for supporting fault tolerance have been discussed in previous work and the hardware for PEBB-based systems was designed so support fault tolerance. However, in spite of the capabilities of the hardware, fault tolerance is not supported yet by existing firmware or software. Improving the PESNet protocol to tolerate Hardware Manager failures will increase the reliability of power electronics systems. Moreover, the additional features that are needed to perform failover also allow recovery from link failures and make hot-swap or plug-and-play of PEBBs possible. Since power electronics systems are real-time systems, it is critical that packets be delivered as soon as possible to their destination. The network latency will limit the granularity of time that the control application can operate on. As a result, methods to implement the required features to meet real-time system requirements are discussed and changes to the protocol are proposed. Changing PESNet will provide reliability gains, depending on the reliability of the components that are used to construct the system. / Master of Science

This thesis presents the design and implementation of a transparent messaging protocol for distributed communication between processors. The processors are designed using dataflow architecture. The protocol ensures transparent asynchronous communication between distributed processes. The protocol is designed such that an application can run without change in virtually any kind of distributed configuration, where configuration is the number of controllers used in the system plus the processor allocation strategy used. It also enables an automated processor allocation strategy to transparently configure an application for any number of processor nodes without requiring any changes or recompilation. The protocol works well even for single-controller applications and for a pre-defined allocation of processors to controllers. The thesis further includes an analysis of the time required for one complete cycle of inter-processor communication. / Master of Science