- About
-
The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 41 to 43 of 43 (0.009 seconds)| 41 |
Integração de um modelo matemático de quantidade de água em rede de fluxo (ACQUANET) com um modelo matemático de qualidade de água em represas (CE-QUAL-R1) - Estudo de Caso: Represa Jaguari-Jacareí - Sistema Cantareira. / Integration of a water quantity mathematical net-flux model (ACQUANET) with a water quality mathematical reservoir model (CE-QUAL-R1) - Case Study: Jaguari-Jacarei Reservoir Cantareira System.Gustavo Doratioto Albano 16 September 2004 (has links)
Desenvolveu-se uma metodologia para integração de dois modelos matemáticos, um de quantidade de água, em rede de fluxo, denominado ACQUANET com outro de qualidade de água, de uma dimensão, aplicado a represas, denominado CE-QUAL-R1. Para tanto, foi elaborada uma INTERFACE em linguagem de programação possibilitando que as vazões resultantes, simuladas pelo ACQUANET, servissem como dados de entrada ao CE-QUAL-R1 para simular a distribuição vertical das variáveis de qualidade de água em uma represa. Essa metodologia foi aplicada à Represa Jaguari-Jacareí no Sistema Cantareira em São Paulo, Brasil, como alternativa de gerenciamento quali-quantitativo, além de possibilitar o uso de retirada de água em diferentes profundidades, através da operação de tomadas dágua seletivas existentes. / A methodology was developed for the integration of two mathematical models, one of water quantity in network named ACQUANET with other of water quality, in one dimension, applied in revervoirs, named CE-QUAL-R1. In order to achieve this goal, an INTERFACE was developed to link the CE-QUAL-R1 with ACQUANET outflow results. It should be highlighted that ACQUANET has been used for beginning values of CE-QUAL-R1 and to simulate the vertical distribution of water quality variables in a reservoir. This methodology was applied to Jaguari-Jacarei Reservoir, of Cantareira System in Sao Paulo, Brazil, as a management quality and quantity tool of the system and it showed the use possibility of withdrawal of outflowing waters from different depths, through existing selective withdrawals ports operation.
|
| 42 |
Development and evaluation of a theoretical model to predict medicines adherence in people with mild to moderate intellectual disability and diabetes : a mixed methods studyPaterson, Ruth Elizabeth January 2018 (has links)
Background: Fifty percent of medications are not taken as prescribed. This is a major public health issue yet there is very limited evidence on the factors associated with medicines adherence in people with mild to moderate Intellectually Disabilities and diabetes (IDD). This study evaluated the frequency of, and factors associated with, medicines non-adherence in this group compared to people without ID but with diabetes (non-IDD).Methods: A systematic review of the literature informed the theoretical model tested. A two-stage, sequential mixed methods study with 111 people with type 1 and 2 diabetes, (IDD = 33, non-IDD = 78) was then carried out. Stage one (quantitative) compared frequency of medication adherence in the group overall, IDD and non-IDD. Univariate and multiple regression analysis evaluated associations between factors (ID, depression, side effects, self-efficacy and perceived level of social support) and medicines non-adherence. Stage two (qualitative) explored findings of stage one with 12 stage one participants' carers using semi-structured interviews. Results: Data were collected between July 2014 and May 2016. The frequency of medicines adherence was similar in the IDD and non-IDD population (70% vs 62%, p = 0.41). The theoretical model did not predict medicines non-adherence. After controlling for support with medicines and complexity of regime (number of medications and use of insulin), depression was an independent predictor in the non-IDD and group overall (p < 0.001). In the IDD group, perceived side effects was an important, but non-significant, predictor of non-adherence (p = 0.06). Carers' perceptions of adherence and depression were consistent with stage one findings. Conclusions: Optimising adherence to diabetes medicines is equally challenging in IDD and non-IDD populations. Associations between independent factors and adherence differed between the two groups: in the non-IDD population, depressive symptoms were associated with non-adherence whereas in the IDD population perceived level of side effects appeared most dominant. Due to small sample sizes findings were inconclusive therefore, a sufficiently powered study further investigating the relationship between adherence and side effects in people with ID and diabetes is recommended.
|
| 43 |
Multi-Frequenz-ESR spinmarkierter ProteineUrban, Leszek 06 December 2012 (has links)
Die Elektronen-Spin-Resonanz-Spektroskopie (ESR) in Verbindung mit ortsspezifischer Spinmarkierung stellt eine hervorragende Möglichkeit dar, um die Struktur und Dynamik von Proteinen aufzuklären. In dieser Dissertation wurden mit Hilfe der Hochfeld-ESR-Spektroskopie (W-Band, 95 GHz, T=160 K) für dreizehn spinmarkierte Colicin A Proben die Polarität und die Protizität der Umgebung der Spinlabelbindestelle bestimmt. Wasserzugänglichkeiten und Wasserstoffbrückenbindungen zum Spinlabel wurden mittels Puls-ESR Methoden (3-Puls-D-ESEEM und Hahn-Echozerfall) bestimmt und die Ergebnisse mit den Polaritäts- und Protizitätswerten korreliert. Raumtemperaturspektren dieser Proben im X-Band (9.5 GHz), Q-Band (34 GHz) und W-Band (95 GHz) liefern Informationen über die Spinlabelbewegung. Mit Hilfe von Molekulardynamiksimulationen (MD) der spinmarkierten kanalbildenden Domäne von Colicin A konnten die Konformationen (Rotameranalyse) und die Dynamik der Spinlabelseitenketten in den unterschiedlichen Umgebungen charakterisiert werden. Der Vergleich der experimentellen mit den aus MD-Trajektorien berechneten ESR-Spektren liefert die Beiträge der unterschiedlichen Rotamerübergänge, die für die beobachteten Spektrenformen charakteristisch sind.
|
Page generated in 0.0139 seconds