Ce travail contribue au programme de recherche et de développement d'un capteur CMOS à pixel qui pourrait satisfaire pleinement les spécifications du nouvel ITS (Inner Tracking System : trajectomètre interne) de l'expérience ALICE. Afin de briser les limites de la CPS de pointe, une technologie CMOS 0.18 µm à quatre puits a été explorée. Les capteurs fabriqués dans cette nouvelle technologie ont montré une meilleure tolérance aux radiations que les capteurs réalisés dans une technologie CMOS 0.35 µm plus ancienne. En outre, cette nouvelle technologie offre la possibilité d’implémenter des transistors de type P dans chaque pixel sans dégrader la capacité de collection de la diode. Il devient donc possible d’intégrer un discriminateur dans chaque pixel et obtenir un pixel à sortie binaire. En conséquence, la consommation sera largement réduite. De plus, le temps de traitement de la ligne peut être potentiellement réduit. Un premier prototype de petite taille, intitulé AROM-0, a été conçu et fabriqué afin d’étudier la faisabilité de la discrimination de signal dans un petit pixel. Dans ce prototype, chaque pixel de surface 22 × 33 µm2 contient une diode de détection, un préamplificateur et un discriminateur à tension d’offset compensée. La performance de bruit des différentes versions de pixels dans le capteur AROM-0 a été évaluée. Ensuite sera détaillé le développement des capteurs AROM-1. Ce sont les capteurs intermédiaires vers le capteur final proposé par notre groupe. Ils ont deux objectifs principaux, l’un est de valider les optimisations de conception du pixel et l’autre est de mettre en place une architecture du capteur évolutive intégrant l’intelligence nécessaire dans le circuit. Cette thèse présente en détail la conception et les résultats de mesure de ces capteurs AROM. / This work is part of the R&D program aimed for a CMOS pixel sensor (CPS) complying with the requirements of the upgrade of the inner tracking system (ITS) of the ALICE experiment. In order break the limitations of the state-of-the-art CPS, a 0.18 µm quadruple-well CMOS process was explored. Besides an enhanced radiation tolerance, with respect to the former sensors fabricated in a 0.35 µm process, the sensor based on this new process allows for full CMOS capability inside the pixel without degradation of the detection efficiency. Therefore, the signal discrimination, which was formerly performed at the column level, can be integrated inside the pixel. As a result, the readout speed and power consumption can be greatly improved as compared to the CPS with column-level discrimination. This work addresses the feasibility study of achieving the signal discrimination withina small pixel (i.e. 22 × 33 µm2), via the prototype named AROM-0. The pixel of AROM-0 contains a sensing diode, a pre-amplifier and an offset compensated discriminator. The noise performance of the various pixel versions implemented in AROM-0 was evaluated. The study was further pursued with the AROM-1 prototypes, incorporating the optimized pixel designs and the necessary on-chip intelligence to approach the final sensor we have proposed for the ALICE-ITS upgrade. This thesis presents in detail the design and the measurement results of these AROM sensors.

Nucleic acids are fundamental molecules of living organisms functioning essentially as the molecular information carriers of life. From how an organism is built to how it responds to external conditions, all of it, can be found in the form of nucleic acid sequences inside every single cell of every life form on earth. Therefore, accessing these sequences provides key information regarding the molecular identity and functional state of any living organism, this is very useful for areas like biomedicine, where accessing and understanding these molecular signatures is the key to develop strategies to understand, treat and diagnose diseases. Decades of research and technological advancements have led to the development of a number of molecular tools and engineering technologies that allow accessing the information contained in the nucleic acids. This thesis provides a general overview of the tools and technologies available for nucleic acid analysis, and proposes an illustrative concept on how molecular tools and emergent technologies can be combined in a modular fashion to design methods for addressing different biomedical questions. The studies included in this thesis, are focused on the particular use of the molecular tools named: padlock and selector probes, rolling circle amplification, and fluorescence detection of single molecules in combination with microfluidics and portable microscopy. By using this combination, it became possible to design and demonstrate novel approaches for integrated nucleic acid analysis, inexpensive digital quantification, mobile-phone based diagnostics and the description of viral infections. These studies represent a step forward towards the adoption of the selected group of tools and technologies, for the design and building of methods that can be used as powerful alternatives to conventional tools used in molecular diagnostics and virology. / <p>At the time of the doctoral defense, the following paper was unpublished and had a status as follows: Paper 1: Manuscript.</p>

Ce travail de thèse présente la démarche utilisée pour construire un modèle éléments finis en statique ou en dynamique d'un pneumatique d'avion gros porteur prenant en compte la géométrie, la structure matérielle complexe, les différents matériaux et leurs propriétés ainsi que les interactions entre le pneumatique et le sol (contact, frottement et couplage thermomécanique). Des essais ont été effectués afin d'identifier les paramètres géométriques et matériaux.Ces simulations utilisant une approche Lagrangienne et une approche mixte Eulérienne/Lagrangienne ont été réalisées sur le modèle proposé. La seconde approche qui réduit considérablement le temps de calcul a été validée pour simuler le roulement en dérapage du pneumatique. Le modèle permet ainsi d'estimer le torseur des efforts dans le contact pneumatique /sol. Nous montrons l'influence des paramètres de chargement (charge verticale, pression de gonflage et vitesse de roulage) et de l'angle de dérapage sur le moment d'autoalignement (MZ) et sur le potentiel d'adhérence (µY) correspondant au rapport entre l'effort latéral et l'effort vertical dû au poids de l'avion. Nous présentons aussi une étude de sensibilité aux paramètres géométriques et matériels.Des essais de Coulomb et de diffusion thermique ont permis d'identifier la loi d'évolution du coefficient de frottement en fonction de la température (béton, asphalte) et l'évolution de la température dans l'épaisseur du pneumatique. Ceci a permis de prendre en compte les effets thermiques dans le modèle et de proposer un modèle de couplage thermomécanique qui met en évidence la décroissance de µY et la chute rapide de MZ vers des valeurs négatives au-delà d'un angle de dérapage critique βmax variant avec les conditions de chargement du pneumatique. Ces variations sont observées expérimentalement. / This PhD Thesis presents the approach adopted for the setting of numerical model based on Finite Element Method for jumbo-jet tire. The model takes into account the real geometry, the complex material structure, the various materials and their properties as well as the interactions between the tire and the ground (contact, friction and thermal-mechanical coupling due to friction). Tests are performed in order to identify geometrical and material parameters.Static and dynamic simulations using a Lagragian approach and an Eulerian/ Lagrangian mixed approach were performed on this proposed model. This second approach which significantly reduces the computational cost time was validated for cornering tire simulation. The model allows thereby to estimate the forces in the tire/ ground contact patch. We show the influency of loading parameters (vertical load, inflating pressure and rolling velocity) and of the slip angle on the self aligning torque (MZ) and on the lateral friction coefficient (µY) corresponding on the ratio between lateral force and vertical load due to the aircraft weight. We also present a sensitivity study on geometrical and material parameters.Coulomb's and thermal diffusion tests were performed in order to identify the friction coefficient law as function of temperature (on concrete and asphalte surfaces) and the temperature evolution in the aircraft tire thickness. These tests allowed to take into account thermal effects in the model and to propose a thermal-mechanical coupling model which emphasized the decreasing of µY and the rapid vanishing of MZ towards zero beyond a critical slip angle βmax varying with the tire loading conditions. These variations were observed experimentally

Ce travail vise à comprendre l’évolution de la texture cristallographique et l’anisotropie du comportement mécanique après laminage à chaud et traitements thermiques d’un Al-Cu-Li 2050 et d’un Al-Zn-Mg-Cu 7050, et expliquer leurs différences. La texture est analysée par EBSD et RX après des essais de compression plane à chaud et après des laminages à chaud industriels. L’anisotropie est étudiée sur des tôles fortes industrielles après différents détensionnements et dans différents états microstructuraux par des essais de traction à 0°, 45° et 90° par rapport à DL. Enfin, nous comparons nos mesures à des résultats simulés par des modèles de plasticité cristalline (modèles de Taylor). Il est montré que, déformés dans des conditions identiques, les deux alliages développent les mêmes textures de laminage jusqu'à une déformation de 2.6. La présence de 1% massique de Li n’est à priori pas responsable d’une texture particulière. En revanche la température de laminage, qui est généralement plus élevée pour les Al-Cu-Li que pour les Al-Zn-Mg-Cu, a un impact important aux grandes déformations, notamment en favorisant la composante Laiton {110}<112>. L'anisotropie d'une tôle laminée de 2050 est pour une large part due à la texture cristallographique. Elle augmente quand un détensionnement est effectué par traction dans la direction DL et diminue quand il est effectué à 45°/DL. La précipitation durcissante, composée de T1 Al2CuLi en forme de plaquettes sur les plans {111}Al, augmente la résistance de la direction préalablement tractionnée mais n'est pas responsable dans nos conditions expérimentales d'une forte aggravation de l'anisotropie. Dans le 7050, l'anisotropie diminue entre l’état mûri naturellement et l’état sur-revenu. La précipitation de sur-revenu du 7050 atténue l'effet de la texture cristallographique sur l'anisotropie et rend, en comparaison, le 2050 d’autant plus anisotrope. / This work aims to understand hot rolling texture evolution and anisotropy of mechanical behaviour on an Al-Cu-Li 2050 and an Al-Zn-Mg-Cu 7050, and aims to explain their differences. Crystallographic textures are analysed by EBSD and X-ray after hot plane strain compressions and after industrial hot rolling. Anisotropy of industrial hot rolled plates is investigated after different stretching and different ageing treatments by means of tensile tests at 0°, 45° and 90° to RD. Experimental results are compared to predictions using plasticity models (Taylor models). It is shown that, under the same processing conditions, the two alloys develop the same rolling textures up to strain of 2.6 ; it can be concluded that the presence of 1wt% of Li does not by itself favour a particular texture. However, it is shown that Brass component {110}<112> is favoured by an increasing rolling temperature, which is generally higher in the Al-Cu-Li than in the Al-Zn-Mg-Cu. Anisotropy of hot rolled 2050 is for a large part caused by crystallographic texture. It increases when stretch axis is at 0° and decreases when stretch axis is at 45°. Hardening precipitation, made by plate shape T1 Al2CuLi lying on the {111}Al, increases yield strength in the stretched direction but it is not responsible in our experimental conditions for a high increase of anisotropy. Anisotropy of 7050 is less important in the over aged state than in the natural aged state. Over ageing precipitation of 7050 reduces the effect of crystallographic texture on the anisotropy and makes 2050 appearing much more anisotropic.

Ce travail réalisé dans le cadre d'une collaboration industrielle avec la société ALSTOM Transport porte sur l'étude de la dégradation des voies ferrées urbaines. Les composantes de voie retenus pour cette étude sont le rail et la dalle de voie en béton. Concernant le rail, différents problèmes sont abordés : contact roue – rail, usure du rail, usure ondulatoire du rail, et fatigue de contact de roulement (RCF) du rail. Un outil numérique avec des interfaces graphiques, nommé CONUS, est développé pour le problème de contact roue – rail et le problème d'usure du rail. Des théories classiques (Hertz, Kalker, Archard, etc.) sont implantées dans cet outil. La méthode stationnaire est implantée dans un code de calcul par éléments finis pour étudier l'état asymptotique de l'acier du rail sous le chargement répété des trains. Ceci nous permet de prédire les régimes de RCF du rail. La mécanique de l'endommagement est utilisée pour prédire la fatigue du matériau béton. Le formalisme de Marigo couplé avec le modèle d'endommagement de Mazars permet de modéliser la dégradation progressive de la rigidité du matériau sous chargement cyclique. Une campagne d'essais de fatigue du béton en flexion a été réalisée. Elle a pour but de valider le modèle théorique et d'identifier les paramètres du matériau. Le dimensionnement d'une dalle de voie en béton a fait l'objet d'une application de cette méthode. Le modèle de réseau de poutres (lattice model) a été utilisé pour étudier la propagation des fissures dans les structures en béton. Ce modèle a été implanté dans le logiciel de calcul par éléments finis, CESAR-LCPC. Les résultats numériques (propagation de fissures) obtenus pour les structures simples sous chargement statique sont en tout point comparables avec les résultats d'essais expérimentaux. Ce modèle a ensuite été utilisé pour étudier la fissuration sous chargement de fatigue. Pour cela un modèle d'endommagement simple modélisant la dégradation des éléments «poutres» s'est avéré suffisant pour décrire la cinématique de propagation des fissures / This work is part of the collaboration between the laboratory Navier (UMR ENPC /IFSTTAR/ CNRS) and ALSTOM Transport company (TGS/Trackway). It focuses on the study of the degradation of urban railways. The components of track considered in this study are the rail and the concrete slab. Regarding the rail, different problems are discussed : wheel – rail contact, rail wear, rail corrugation and rolling contact fatigue (RCF). A numerical tool with graphical interfaces, called CONUS, is developed to predict the behaviour of the wheel - rail contact, the rail wear, and the rail corrugation problems. Classical theories (Hertz, Kalker, Archard, etc...) are implemented in this tool. The stationary method is implemented in a finite element software to study the asymptotic state of the rail steel under repeated loading of trains.The damage mechanics is used to predict the fatigue life of concrete. Marigo's formalism coupled with Mazars' damage model is used to predict the gradual degradation of material stiffness under cyclic loading. A campaign of fatigue tests for concrete in bending was conducted. It aims at validating the theoretical model and identifying material parameters. We applied this method in order to design the concrete slabs of urban railway. The lattice model was used to study the crack propagation in concrete structures. This model was implemented in the finite element software, CESAR-LCPC. The numerical results obtained for simple structures under static loading are consistent with the results of laboratory experiments. This model was then used to study the crack propagation under fatigue loading. For that purpose, a simple damage model of degradation of the "beams" elements describes the kinematics of crack propagation with a satisfying accuracy

<p>Forest management involves numerous stochastic elements. To sustainably manage forest resources, it is crucial to acknowledge these sources as uncertainty or risk, and incorporate them in adaptive decision-making. Here, I developed several stochastic programming models in the form of passive or active adaptive management for natural mixed-species hardwood forests in Indiana. I demonstrated how to use these tools to deal with time-invariant and time-variant natural disturbances in optimal planning of harvests.</p> <p> Markov decision process (MDP) models were first constructed based upon stochastic simulations of an empirical forest growth model for the forest type of interest. Then, they were optimized to seek the optimal or near-optimal harvesting decisions while considering risk and uncertainty in natural disturbances. In particular, a classic expected-criterion infinite-horizon MDP model was first used as a passive adaptive management tool to determine the optimal action for a specific forest state when the probabilities of forest transition remained constant over time. Next, a two-stage non-stationary MDP model combined with a rolling-horizon heuristic was developed, which allowed information update and then adjustments of decisions accordingly. It was used to determine active adaptive harvesting decisions for a three-decade planning horizon during which natural disturbance probabilities may be altered by climate change.</p> <p> The empirical results can be used to make some useful quantitative management recommendations, and shed light on the impacts of decision-making on the forests and timber yield when some stochastic elements in forest management changed. In general, the increase in the likelihood of damages by natural disturbance to forests would cause more aggressive decisions if timber production was the management objective. When windthrow did not pose a threat to mixed hardwood forests, the average optimal yield of sawtimber was estimated to be 1,376 ft³/ac/acre, while the residual basal area was 88 ft²/ac. Assuming a 10 percent per decade probability of windthrow that would reduce the stand basal area considerably, the optimal sawtimber yield per decade would decline by 17%, but the residual basal area would be lowered only by 5%. Assuming that the frequency of windthrow increased in the magnitude of 5% every decade under climate change, the average sawtimber yield would be reduced by 31%, with an average residual basal area slightly around 76 ft²/ac. For validation purpose, I compared the total sawtimber yield in three decades obtained from the heuristic approach to that of a three-decade MDP model making <i>ex post</i> decisions. The heuristic approach was proved to provide a satisfactory result which was only about 18% lower than the actual optimum.</p> These findings highlight the need for landowners, both private and public, to monitor forests frequently and use flexible planning approaches in order to anticipate for climate change impacts. They also suggest that climate change may considerably lower sawtimber yield, causing a concerning decline in the timber supply in Indiana. Future improvements of the approaches used here are recommended, including addressing the changing stumpage market condition and developing a more flexible rolling-horizon heuristic approach.

Im Rahmen der vorliegenden Arbeit wurde eine Warmwalztechnologie für gießgewalztes Vorband der calciumhaltigen Magnesiumlegierung Mg-2Zn-1Al-0,3Ca (ZAX210) entwickelt. Ausgangspunkt war die Untersuchung des Verformungs- und Rekristallisationsverhaltens in Abhängigkeit der Umformtemperatur, Umformgeschwindigkeit und des Umformgrades. Dabei wurde die zwillingsinduzierte dynamische Rekristallisation als dominierender Rekristallisationsmechanismus vor allem bei erhöhten Umformgeschwindigkeiten identifiziert. Basierend auf den daraus gewonnenen Erkenntnissen konnte ein Prozessfenster für das Warmwalzen abgeleitet werden, welches die Erzeugung eines 2 mm dicken Fertigbandes mit abgeschwächter Textur, guten mechanischen Eigenschaften und einer verbesserten Umformbarkeit, insbesondere im Vergleich zu den Standardknetlegierungen AZ31 und ZE10, erlaubte. Die Warmwalzparameter sind unter Berücksichtigung gleicher Randbedingungen auf einen industriellen Warmwalzprozess übertragbar.

The thesis summarizes general and up-to-date knowledge of descaling during the continuous production of the hot-rolled steel and proposes further streamlining of this process in industrial production. The first chapter of the thesis deals with the origin, structure and physical properties of the scales. The second chapter describes the principles of descaling by using a high pressure flat water jet. The third chapter introduces the principles of the experimental methods and describes the used laboratory equipment. The fourth chapter summarizes the description of the particular experiments and their evaluation, and thus represents the focus of the dissertation. It is divided into six sections which independently solve predefined objectives of the dissertation. The first section focuses on the height and structure development of the scales on 54SiCr6 and HDT580X steels. It has been proven that the height of the formed scales increases with the time and temperature of the oxidation. The layered nature of the scales was verified at the same time. The second section examines the effect of the nozzle stabilizer on the focussing and distribution of the impact pressure of the nozzle. Experiments have shown that increase of 11 % of an average maximum nozzle pressure can be achieved, depending on the type of nozzle and the length of the stabilizer. The third section deals with the analysis of shadowgraphy images of water jet structures of the nozzles. A script was developed for analysis of these shadowgraphy photos by an adaptive thresholding. The findings are correlated using a regression analysis with an average heat transfer coefficient. It has been reported that most of the standard nozzle configurations produced disintegrated stream of little droplets at the height of the rolled surface. The fourth section focuses on the area of water jet overlap, especially the area of the so-called washout, where the impact pressure of one nozzle is reduced by the nozzle stream of the other. The influence of the pressure change and the mutual displacement of the nozzles is investigated. The analysis showed that the change of pressure did not have any effect on the percentage of reduction of the impact pressure in the area of the washout. It has been shown that if the area of the washout is wide the descaling efficiency in this area may be reduced. The fifth section builds on the previous section and focuses directly on the areas of waterjet overlaps. The influence of the change of rotation and pitch of the nozzles is studied. Experiments have shown that small changes in nozzle pitch do not have a significant impact on impact pressure and heat transfer coefficient. The effect of nozzle rotation, on the other hand, was a significant factor for the efficiency and homogeneity of the descaling of the surface. The last section deals with the effect of the rolling speed on the heat transfer coefficient in the descaling process. The regression model has shown that with a higher rolling speed there is a reduction in the average heat transfer coefficient. Conclusion summarizes the results of the dissertation and proposes which findings can be used in the industry to make the descaling process more effective.

The thesis focuses on the optimization of the central lubrication system for the lubrication of rolling bearings of rolling mills in the operation continuous wire rod mill. The work is divided into theoretical and practical part. The first part of the theoretical work is focuses on the search of rolling and tribodiagnostics. The next part focuses on the description of modern central lubrication systems, explanation of their principle and practical use. The practical part explains the function of the old lubrication system for rolling mill bearings with an analysis of its problems. Next is described the technical design of a new central lubrication system, its application into operation and its actual commissioning are described. The last part of the thesis is the conclusion and evaluation of the benefits of the new central lubrication system compared to the old one.

This master's thesis deal the system, which use the Frequency Hopping (FH). Is explained principle those techniques and her benefits and disadvantages. Follows description techniques Adaptive Frequency Hopping (AFH) that used the Bluetooth. Follows description other method for setup hopset such as Dynamic Frequency Hopping (DFH), which used standards 802.22. 22. Is an emerging standard for Wireless Regional Area Networks (WRAN) operating on a license-exempt and non-interference basis in the spectrum allocated to TV broadcast services (between 47–910 MHz). Other method introduces the Adaptive Frequency Rolling (AFR), a particular instance of frequency hopping (FH) that enables the collocated WPANs to cooperate and avoid the self-interference. The AFR uses as input solely the observed packet error rate (PER) and it does not require any exchange of information among the collocated WPANs. The effect of the FR over a longer time interval is that the WPANs use the complete set of disposable channels in an implicit time-division and cooperative manner. Last method described in this Thesis is Dynamic Adaptive Frequency Hopping (DAFH). The basic strategy applied in DAFH is a binary search for a hopset that offers smaller PER. The set of admissible hopsets depends on the total number of available channels and the maximal level of binary divisions. Practical part of the master's thesis describes proposal model AFH, with usage of Matlab Simulink programme. In thesis are described function each blocks a their setting. Simulation parameters can change in simple graphic interface. The model is able to simulate influence of static and dynamic interference in transmission band of two communicating devices.