Introdução: Nas últimas décadas, vários fatores determinaram importantes modificações no modo de prover assistência psiquiátrica. Entre estes, destacam-se as mudanças no modo como entendemos os transtornos mentais, os avanços e melhora na disponibilidade de tratamentos psiquiátricos, o aumento do interesse político em saúde mental, além da ênfase nos custos da assistência médica. Com isto, a internação psiquiátrica passou a representar uma parcela menor entre os recursos utilizados na assistência em saúde mental. A Psiquiatria hospitalar atual cumpre a função de realizar diagnóstico e tratar sintomas agudos com a finalidade de esbater riscos, focada em estabilização, segurança do paciente e curta permanência. Neste contexto, o estudo de desfechos negativos entre pacientes que internam em leito psiquiátrico de hospital geral torna-se cada vez mais necessário. Objetivos: Identificar determinantes de desfechos negativos entre pacientes que internaram em leito psiquiátrico de hospital geral, definidos a priori como tempo de internação prolongado, reinternação e morte por qualquer causa em um ano a partir do momento da alta hospitalar. Métodos: Estudo naturalístico, longitudinal e prospectivo, realizado em unidade psiquiátrica de um hospital geral universitário de nível terciário. Pacientes admitidos entre junho de 2011 e dezembro de 2013 com 18 anos ou mais foram considerados elegíveis, exceto os que tivessem transtorno por uso de substâncias como diagnóstico principal, agitação psicomotora grave nas primeiras 72 horas da admissão, comprometimento cognitivo suficiente para comprometer a avaliação ou recusa em participar da pesquisa. Dados sociodemográficos e clínicos foram coletados na admissão, alta e um ano após a alta. Resultados: No artigo 1, seis variáveis explicaram 14,6% da variabilidade no tempo de internação: ausência de renda própria, história de internações psiquiátricas nos últimos dois anos, escore total na Brief Psychiatric Rating Scale e na Clinical Global Impression, diagnóstico de Esquizofrenia e história de tentativas de suicídio. O artigo 2 reafirmou o papel das internações anteriores em predizer internações futuras (RC1.38; IC 1.16-1.60) e demonstrou que para pacientes que internaram em episódio depressivo, não estar em remissão no momento da alta aumenta o risco de reinternação (RC 2.40; IC 1.14-5.07), assim como maiores escores na Brief Psychiatric Rating Scale no momento da alta para aqueles admitidos por Esquizofrenia. O artigo 3 reportou a mortalidade entre os pacientes acompanhados um ano 9 após a alta, mais de três vezes maior que a mortalidade da população geral para o mesmo período e área geográfica. Discussão: Os três estudos produzidos por esta tese colaboram para o corpo de evidências sobre desfechos adversos entre pacientes que internaram em leito psiquiátrico de hospital geral. O modelo de internação psiquiátrica em hospital geral é amplamente defendido pela Psiquiatria contemporânea como o melhor para tratamento de agudizações de transtornos mentais graves. Entretanto, não é o modelo majoritário tanto no Brasil como no mundo. Portanto, os resultados desta tese refletem os desfechos de um modelo assistencial preconizado, porém não predominante. Considerações finais: Ainda carecemos de pesquisas que se dediquem a avaliar desfechos negativos em internação psiquiátrica de hospital geral. / Introduction: In the last decades, several factors have determined significant changes in the way to provide psychiatric care. These include changes in the way we understand mental disorders, advances and improvements in the availability of psychiatric treatments, increased political interest in mental health, and emphasis on health care costs. With this, psychiatric hospitalization started to represent a smaller portion of the resources used in mental health care. It fulfills the function of diagnosing and treating acute symptoms with the purpose of avoiding risks, being focused on stabilization, patient safety and short stay. In this context, the study of negative outcomes among patients hospitalized in the psychiatric beds of general hospital becomes more and more necessary. Objectives: To identify determinants of adverse outcomes in patients admitted in psychiatric beds of a general hospital, defined a priori as longer hospital stay, rehospitalization and death from any cause one year after discharge. Methods: This is a naturalistic, longitudinal and prospective study carried out in a psychiatric unit of a general university-level tertiary care hospital. Patients admitted between June 2011 and December 2013 aged 18 years and over were considered eligible, except those who had substance use disorders as the main diagnosis, severe psychomotor agitation in the first 72 hours of admission, cognitive impairment sufficient to compromise the evaluation or refusal to participate in the research. Sociodemographic and clinical data were collected on admission, discharge and one year after discharge. Results: In article 1, six variables explained 14,6% of the variability of length-of-stay: absence of own income, history of psychiatric hospitalizations in the last two years, the total score of Brief Psychiatric Rating Scale and Clinical Global Impression, Schizophrenia diagnosis and history of suicide attempts. Article 2 reaffirmed the role of previous admissions in predicting future hospitalizations. Also, for patients admitted in a depressive episode, not being in remission at discharge increases the chance to be readmitted (OR 2.40; CI 1.14-5.07), as well as higher scores in the Brief Psychiatric Rating Scale at discharge for patients with Schizophrenia (OR 1.28, CI 1.11-1.48). Article 3 reported the mortality among patients followed up, more than three times greater than the mortality of the general population for the same period and geographical area. Discussion: The three studies produced by this thesis collaborate to the body of evidence about adverse outcomes among patients admitted in psychiatric beds of a general hospital. Contemporary psychiatry widely advocates the model of psychiatric hospitalization in general hospital as the best for treatment of acute mental disorder exacerbations. However, it is not the majority model in Brazil as in the world. Therefore, the results of this thesis reflect the outcomes of a recommended, but not predominant, care model. Final considerations: We still lack researches that focus on evaluating negative outcomes in general hospital psychiatric hospitalization.

Introdução: Nas últimas décadas, vários fatores determinaram importantes modificações no modo de prover assistência psiquiátrica. Entre estes, destacam-se as mudanças no modo como entendemos os transtornos mentais, os avanços e melhora na disponibilidade de tratamentos psiquiátricos, o aumento do interesse político em saúde mental, além da ênfase nos custos da assistência médica. Com isto, a internação psiquiátrica passou a representar uma parcela menor entre os recursos utilizados na assistência em saúde mental. A Psiquiatria hospitalar atual cumpre a função de realizar diagnóstico e tratar sintomas agudos com a finalidade de esbater riscos, focada em estabilização, segurança do paciente e curta permanência. Neste contexto, o estudo de desfechos negativos entre pacientes que internam em leito psiquiátrico de hospital geral torna-se cada vez mais necessário. Objetivos: Identificar determinantes de desfechos negativos entre pacientes que internaram em leito psiquiátrico de hospital geral, definidos a priori como tempo de internação prolongado, reinternação e morte por qualquer causa em um ano a partir do momento da alta hospitalar. Métodos: Estudo naturalístico, longitudinal e prospectivo, realizado em unidade psiquiátrica de um hospital geral universitário de nível terciário. Pacientes admitidos entre junho de 2011 e dezembro de 2013 com 18 anos ou mais foram considerados elegíveis, exceto os que tivessem transtorno por uso de substâncias como diagnóstico principal, agitação psicomotora grave nas primeiras 72 horas da admissão, comprometimento cognitivo suficiente para comprometer a avaliação ou recusa em participar da pesquisa. Dados sociodemográficos e clínicos foram coletados na admissão, alta e um ano após a alta. Resultados: No artigo 1, seis variáveis explicaram 14,6% da variabilidade no tempo de internação: ausência de renda própria, história de internações psiquiátricas nos últimos dois anos, escore total na Brief Psychiatric Rating Scale e na Clinical Global Impression, diagnóstico de Esquizofrenia e história de tentativas de suicídio. O artigo 2 reafirmou o papel das internações anteriores em predizer internações futuras (RC1.38; IC 1.16-1.60) e demonstrou que para pacientes que internaram em episódio depressivo, não estar em remissão no momento da alta aumenta o risco de reinternação (RC 2.40; IC 1.14-5.07), assim como maiores escores na Brief Psychiatric Rating Scale no momento da alta para aqueles admitidos por Esquizofrenia. O artigo 3 reportou a mortalidade entre os pacientes acompanhados um ano 9 após a alta, mais de três vezes maior que a mortalidade da população geral para o mesmo período e área geográfica. Discussão: Os três estudos produzidos por esta tese colaboram para o corpo de evidências sobre desfechos adversos entre pacientes que internaram em leito psiquiátrico de hospital geral. O modelo de internação psiquiátrica em hospital geral é amplamente defendido pela Psiquiatria contemporânea como o melhor para tratamento de agudizações de transtornos mentais graves. Entretanto, não é o modelo majoritário tanto no Brasil como no mundo. Portanto, os resultados desta tese refletem os desfechos de um modelo assistencial preconizado, porém não predominante. Considerações finais: Ainda carecemos de pesquisas que se dediquem a avaliar desfechos negativos em internação psiquiátrica de hospital geral. / Introduction: In the last decades, several factors have determined significant changes in the way to provide psychiatric care. These include changes in the way we understand mental disorders, advances and improvements in the availability of psychiatric treatments, increased political interest in mental health, and emphasis on health care costs. With this, psychiatric hospitalization started to represent a smaller portion of the resources used in mental health care. It fulfills the function of diagnosing and treating acute symptoms with the purpose of avoiding risks, being focused on stabilization, patient safety and short stay. In this context, the study of negative outcomes among patients hospitalized in the psychiatric beds of general hospital becomes more and more necessary. Objectives: To identify determinants of adverse outcomes in patients admitted in psychiatric beds of a general hospital, defined a priori as longer hospital stay, rehospitalization and death from any cause one year after discharge. Methods: This is a naturalistic, longitudinal and prospective study carried out in a psychiatric unit of a general university-level tertiary care hospital. Patients admitted between June 2011 and December 2013 aged 18 years and over were considered eligible, except those who had substance use disorders as the main diagnosis, severe psychomotor agitation in the first 72 hours of admission, cognitive impairment sufficient to compromise the evaluation or refusal to participate in the research. Sociodemographic and clinical data were collected on admission, discharge and one year after discharge. Results: In article 1, six variables explained 14,6% of the variability of length-of-stay: absence of own income, history of psychiatric hospitalizations in the last two years, the total score of Brief Psychiatric Rating Scale and Clinical Global Impression, Schizophrenia diagnosis and history of suicide attempts. Article 2 reaffirmed the role of previous admissions in predicting future hospitalizations. Also, for patients admitted in a depressive episode, not being in remission at discharge increases the chance to be readmitted (OR 2.40; CI 1.14-5.07), as well as higher scores in the Brief Psychiatric Rating Scale at discharge for patients with Schizophrenia (OR 1.28, CI 1.11-1.48). Article 3 reported the mortality among patients followed up, more than three times greater than the mortality of the general population for the same period and geographical area. Discussion: The three studies produced by this thesis collaborate to the body of evidence about adverse outcomes among patients admitted in psychiatric beds of a general hospital. Contemporary psychiatry widely advocates the model of psychiatric hospitalization in general hospital as the best for treatment of acute mental disorder exacerbations. However, it is not the majority model in Brazil as in the world. Therefore, the results of this thesis reflect the outcomes of a recommended, but not predominant, care model. Final considerations: We still lack researches that focus on evaluating negative outcomes in general hospital psychiatric hospitalization.

In the United States, the health care sector is 20 years behind in the use of information technology to improve the process of health care delivery as compared to other sectors. Patients have to deliver their data over and over again to every health professional they see. Most health care facilities act as data repositories with limited capabilities of data analysis or data exchange. A remaining challenge is, how do we encourage the use of IT in the health care sector that will improve care coordination, save lives, make patients more involved in decision-making, and save money for the American people? According to Healthy People 2020, several challenges such as making health IT more usable, helping users to adapt to the new uses of health IT, and monitoring the impact of health IT on health care quality, safety, and efficiency, will require multidisciplinary models, new data systems, and abundant research. In this dissertation, I developed and used systems engineering methods to understand the role of new health IT in improving the coordination, safety, and efficiency of health care delivery. It is well known that care coordination issues may result in preventable hospital readmissions. In this dissertation, I identified the status of the care coordination and hospital readmission issues in the United States, and the potential areas where systems engineering would make significant contributions (see Appendix B). This literature review introduced me to a second study (see Appendix C), in which I identified specific patient cohorts, within chronically ill patients, that are at a higher risk of being readmitted within 30 days. Important to note is that the largest volume of preventable hospital readmissions occurs among chronically ill patients. This study was a retrospective data analysis of a representative patient cohort from Tampa, Florida, based on multivariate logistic regression and Cox proportional hazards models. After finishing these two studies, I directed my research efforts to understand and generate evidence on the role of new health IT (i.e., health information exchange, HIE) in improving care coordination, and thereby reducing the chances of a patient to be unnecessarily readmitted to the hospital. HIE is the electronic exchange of patient data among different stakeholders in the health care industry. The exchange of patient data is achieved, for example, by connecting electronic medical records systems between unaffiliated health care providers. It is expected that HIE will allow physicians, nurses, pharmacists, other health care providers and patients to appropriately access and securely share a patient’s vital medical information electronically, and thereby improving the speed, quality, safety and cost of patient care. The federal government, through the 2009 Health Information Technology for Economic and Clinical Health (HITECH) Act, is actively stimulating health care providers to engage in HIE, so that they can freely exchange patient information. Although these networks of information exchange are the promise of a less fragmented and more efficient health care system, there are only a few functional and financially sustainable HIEs across the United States. Current evidence suggests four barriers for HIE: •Usability and interface issues of HIE systems •Privacy and security concerns of patient data •Lack of sustainable business models for HIE organizations •Loss of strategic advantage of "owning" patient information by joining HIE to freely share data To contribute in reducing usability and interface issues of HIE systems, I performed a user needs assessment for the internal medicine department of Tampa General Hospital in Tampa, Florida. I used qualitative research tools (see Appendix D) and machine learning techniques (see Appendix E) to answer the following fundamental questions: How do clinicians integrate patient information allocated in outside health care facilities? What are the types of information needed the most for efficient and effective medical decision-making? Additionally, I built a strategic gaming model (see Appendix F) to analyze the strategic role of "owning" patient information that health care providers lose by joining an HIE. Using bilevel mathematical programs, I mimic the hospital decision of joining HIE and the patient decision of switching from one hospital to another one. The fundamental questions I tried to answer were: What is the role of competition in the decision of whether or not hospitals will engage in HIE? Our mathematical framework can also be used by policy makers to answer the following question: What are the optimal levels of monetary incentives that will spur HIE engagement in a specific region? Answering these fundamental questions will support both the development of user-friendly HIE systems and the creation of more effective health IT policy to promote and generate HIE engagement. Through the development of these five studies, I demonstrated how systems engineering tools can be used by policy makers and health care providers to make health IT more useful, and to monitor and support the impact of health IT on health care quality, safety, and efficiency.

Introduction: Acute Coronary Syndrome (ACS) is responsible for raising admissions numbers and hospital readings. Patients are associated with increased costs to the patient and the health system, as well as access to hospital mortality rates. Objective: To investigate rehospitalization factors in patients with ACS. Methodology: This is a retrospective study of patients of both sexes, adults and elderly, diagnosed with ACS. The records of health and health cases were evaluated in relation to cardiology, the occurrence of rehospitalization, the time between admissions and the use of medications at the time of rehospitalization, up to one year after admission for ACS. Logistic regression was used to evaluate the predictive variables of rehospitalization. Results: The occurrence of readmissions was 21.46% (n = 115) and the mean period between hospitalizations was 122.74 (SD 112.14) days. Most patients were male (64.0%), mean age was 63.15 years (SD 12.26) years, 7% had readmission and 68.7% had more than one readmission in 01 year. The cardiovascular causes, among them, the recurrence of ACS, were the most prevalent among hospital readmissions. Public utility (OR 0.46) and the diagnosis of CHF (OR 1.81) were associated with reintroduction following multiple logistic regression. Conclusion: As the rehospitalizations are therapeutic and they return to help health professionals and are associated with the recurrence of the ACS event and the type of care. / Introdução: A Síndrome Coronariana Aguda (SCA) é responsável por elevados números de admissões e readmissões hospitalares. Esses números estão associados ao aumento dos custos para o paciente e para o sistema de saúde, bem como à elevação nas taxas de mortalidade hospitalar. Objetivo: Investigar os determinantes de reinternação entre pacientes com SCA. Metodologia: Trata-se de uma coorte retrospectiva de pacientes de ambos os sexos, adultos e idosos, diagnosticados com SCA. Foram avaliados, a partir dos registros dos hospitais locais públicos e privados de referência em cardiologia, a ocorrência de reinternação, em até 01 ano após a internação por SCA, o tempo entre as admissões e uso de medicamentos no momento da reinternação. Regressão logística múltipla foi utilizada para avaliar as variáveis preditoras da reinternação. Resultados: A ocorrência de reinternações foi de 21,46% (n=115) e o período médio entre as internações foi de 122,74 (DP 112,14) dias. Os pacientes avaliados eram, em sua maioria, do sexo masculino (64,0%), com média de idade de 63,15 (DP 12,26) anos, 7% apresentaram óbito na reinternação e 68,7% apresentaram mais de uma reinternação em 01 ano. As causas cardiovasculares, entre elas a recorrência da SCA, foram as mais prevalente entre as reinternações hospitalares. A assistência pública (OR 0,46) e o diagnóstico de ICC (OR 1,81) tiveram associados às reintrenação após a regressão logística múltipla. Conclusão: As reinternações são reflexo das condições clínicas do paciente e ao acesso do paciente aos serviços de saúde e estão associadas a recorrência do evento de SCA e o tipo de assistência. / Aracaju

A crescente preocupação sobre as infecções relacionadas à assistência à saúde levou a Organização Mundial da Saúde a promover a criação da Aliança Mundial para a Segurança do Paciente, enfatizando ações básicas de controle de infecções. A redução de sua incidência implica em proteção para o paciente, profissionais e instituições, favorecendo a prestação da assistência livre de riscos. Dentre as mais frequentes, a infecção do sítio cirúrgico deve ser compreendida como elemento qualificador do cuidado e, os dados relacionados, o ponto de partida para as ações preventivas e de controle. Os hospitais têm dificuldades para realizar a vigilância epidemiológica pós-alta, tarefa complexa haja vista a tendência de redução do tempo de internação. Conhecer dados sobre a readmissão contribui para melhorar os dados de vigilância pós-alta. Foi realizado um estudo exploratório com o objetivo de descrever a epidemiologia das readmissões por infecções de sítio cirúrgico em pacientes em um hospital público de Belo Horizonte (MG). Foram avaliados 98 registros médicos e da Comissão de Controle de Infecção Hospitalar referentes aos indivíduos readmitidos por este motivo entre janeiro/2008 e dezembro/2009. Os resultados demonstraram que um quarto dos pacientes que desenvolveu infecção do sítio cirúrgico na instituição necessitou de nova internação. A idade média dos indivíduos foi de 57,2 anos; mais da metade apresentava diabetes mellitus, e um terço, hipertensão arterial sistêmica; no entanto, o risco anestésico para a maioria foi classificado como baixo. As infecções ocorreram com maior frequência em cirurgias limpas e potencialmente contaminadas, e as especialidades com maior número de pacientes readmitidos foram ortopedia, com mais da metade dos procedimentos relacionados à correção de fraturas, e cirurgia geral, na qual as hernioplastias/rafias e colecistectomias predominaram. Metade dos indivíduos recebeu biomaterial em suas intervenções. Os tempos cirúrgicos e de internação não diferiram dos estudos encontrados na literatura. Praticamente todos os pacientes utilizaram antibioticoprofilaxia, segundo protocolo da instituição. Os primeiros sinais e sintomas surgiram, em média, após 33,2 dias, e metade dos infectados teve o diagnóstico nos primeiros 30 dias de pós-operatório. A classificação das infecções mostrou que metade dos pacientes apresentou infecção de órgãos e cavidades e, para 60% deles, foram necessárias novas intervenções cirúrgicas, além do tratamento antimicrobiano. O micro-organismo predominante nas infecções ortopédicas foi Staphylococcus aureus e nas infecções da cirurgia geral Escherichia coli, ambos com perfil de resistência abaixo daqueles encontrados na literatura. O estudo permite concluir que a vigilância pós-alta e o monitoramento das taxas de readmissão contribuem para o redimensionamento do problema e definição de ações pontuais para seu controle. / The growing concern about infections related to health care led the World Health Organization to promote the creation of the World Alliance for Patient Safety, emphasizing basic actions to infection control. The reduction in the incidence of surgical site infection implies protection for patients, professionals and institutions favoring the assistance free of risks. Among the most frequent, surgical site infection should be understood as a qualifying element of care, and related data, the starting point for preventive and control measures. Hospitals have difficulties in achieving post-discharge surveillance, complex task given the trend of reduced hospital stay. Knowledge of the of readmission rates helps to improve reporting of post-discharge surveillance. An exploratory and descriptive study was conducted in order to describe the epidemiology of readmissions for surgical site infections in patients in a governmental hospital in Belo Horizonte (MG). We evaluated 98 medical records and the reports of the Hospital Infection Control Committee related to readmitted patients for this reason among january/2008 and december/2009. The results showed that one quarter of patients who developed surgical site infection in the hospital needed a new hospitalization. The mean age of subjects was 57.2 years; more than a half had diabetes mellitus, and a third, hypertension, however, the anesthetic risk for the majority was classified as low. The infections occurred more frequently in clean and potentially contaminated surgeries and the medical specialties with higher number of patients readmitted was orthopedic, with more than half of surgeries related to the correction of fractures, and general surgery, where the hernia and gallbladder surgery predominated. Half of the subjects received biomaterial in its proceedings. The surgical and hospitalization times did not differ from others studies in the literature. Virtually all patients received antibiotic prophylaxis for indications mentioned in the protocol. Early signs and symptoms appeared after an average of 33.2 days, and half of the patients were diagnosed within the first 30 days postoperatively. The classification of infections showed that half of the patients had infection of organs and cavities and 60% were required surgical interventions, in addition to antimicrobial treatment. Staphylococcus aureus predominated in orthopedic procedures and Escherichia coli in general surgery, both with multi-resistance profile below the results presented in other studies. The study concludes that the post-discharge surveillance and monitoring of readmission rates contribute to the scaling of the problem and define specific actions for its control.

As concepções sobre a loucura, bem como as formas de tratá-la, vêm sofrendo consideráveis transformações de acordo com a cultura e as épocas. A partir da década de 1990, foi oficializada a Reforma Psiquiátrica no Brasil, dando início à política de desinstitucionalização e reinserção social. Todavia, ainda são verificados alguns desafios, entre estes, as reinternações no setor de internação breve em um hospital psiquiátrico, o que traz sérias consequências, como a propensão a uma nova modalidade de institucionalização. Este estudo teve como objetivos: analisar o fenômeno da reinternação psiquiátrica no contexto da Atenção Psicossocial, a partir da visão dos pacientes reinternantes em um hospital psiquiátrico público; compreender o processo de reinternação psiquiátrica ao qual o paciente está sujeito; investigar o cenário assistencial e sociofamiliar e suas interferências no fenômeno da reinternação psiquiátrica; explorar, junto aos pacientes, a existência de perspectivas que vislumbrem saídas às repetidas internações psiquiátricas. Inicialmente, com vistas a sintetizar e analisar a produção científica nacional e internacional acerca do fenômeno da reinternação psiquiátrica, no contexto da desinstitucionalização, foi realizada uma revisão integrativa da literatura publicada em fontes de pesquisa de impacto que detectou deficiência de estudos que investigassem variáveis psicossociais envolvidas na problemática, bem como ausência da perspectiva do paciente sobre o assunto. O presente estudo fundamentou-se na Atenção Psicossocial, enquanto corpo teórico-prático e ético, e orientou-se pela reabilitação psicossocial como categoria analítica. A Atenção Psicossocial emerge no atual contexto de transição paradigmática, a partir da crise do paradigma da racionalidade científica, e baseia-se no pensamento da complexidade. Para a coleta dos dados, foi aplicado um roteiro de entrevista semiestruturada a 22 pacientes reinternantes no hospital investigado, bem como coletadas informações sociodemográficas constantes dos seus prontuários. Os dados colhidos foram submetidos à análise de conteúdo, por meio da qual foram construídas as seguintes categorias temáticas: Funções e disfunções do tratamento hospitalar: os sentidos da internação psiquiátrica; Tratamento ambulatorial: repetir ou inovar?; A medicação e seus impasses: benefícios e limites percebidos; Família laços e embaraços: uma convivência possível?; A dimensão social extramuros: construindo lugares possíveis; O momento da alta: o que está por vir daqui para frente. A partir da análise dos dados, constatou-se uma combinação de carências: ausência de apoio familiar desejável, inexistência de trabalho ou de ocupação agradável, dificuldade na apropriação do espaço de moradia, falta de redes de apoio ou de laços sociais, insuficiência dos serviços extra-hospitalares e a ineficiência da assistência que resultam na não adesão ao tratamento, incluindo o medicamentoso. Este cenário favorece o isolamento social e contribui para que, nos momentos de crise, não havendo possibilidade de acolhida do sofrimento no serviço, o hospital seja o recurso mais utilizado pelo paciente. Assim, a coexistência de modelos antagônicos, hospitalar e comunitário, produz um novo fenômeno, que, no entanto, reproduz o velho: a reinternação psiquiátrica que leva à reedição da institucionalização. Nessa direção, a reinternação psiquiátrica, como fenômeno atual, desvela o processo ainda inconcluso e não consolidado da Reforma Psiquiátrica, bem como confirma que a efetiva desinstitucionalização só ocorre com a devida substituição do modelo hospitalar pelo modelo de Atenção Psicossocial. / Conceptions about madness, as well as how to treat it, have been undergoing considerable changes according to culture and period. From the 1990s, the Psychiatric Reform was official in Brazil, starting the policy of deinstitutionalization and social reintegration. However, a few challenges are still observed, including the readmissions in the sector of brief hospitalization in a psychiatric hospital, which has serious consequences, such as the propensity to a new form of institutionalization. This study aimed to: analyze the phenomenon of psychiatric readmission in the context of Psychosocial Care, from the perspective of readmitted patients in a public psychiatric hospital; understand the process of psychiatric readmission to which the patient is likely to be submitted; investigate the assistance, social and familial scenario and their interference in the phenomenon of psychiatric readmission; explore, together with the patients, the existence of perspectives that envisage other possibilities to repeated psychiatric hospitalizations. Initially, in order to synthesize and analyze the national and international scientific production about the phenomenon of psychiatric readmission in the context of deinstitutionalization, an integrative review of the literature was conducted in research sources of impact. It was found a deficiency of studies that investigate psychosocial variables involved in the problem, as well as an absence of the patient\'s perspective on the subject. The present study was based on the Psychosocial Care, as a theoretical, practical and ethical reference, and was also guided by psychosocial rehabilitation as an analytical category. The Psychosocial Care emerges in the current context of paradigmatic transition, from the crisis of the scientific rationality´s paradigm, and it is based on the thought of complexity. To collect data, a semi-structured interview was applied to 22 readmitted patients in the investigated hospital, as well as the collection of their social and demographic information contained in their hospital records. Data were submitted to content analysis, through which the following thematic categories we developed: Functions and dysfunctions of hospital treatment: the meanings of psychiatric hospitalization; Outpatient treatment: repeat or innovate?; Medication and its impasses: perceived benefits and limits; Family ties and embarrassments: a possible coexistence?; The extramural social dimension: building possible places; The time of discharge: what is to come hereafter. From the data analysis, it was found a combination of deficiencies: lack of desirable family support, lack of pleasant work or occupation, difficulties in the appropriation of the living space, lack of support networks or social ties, lack of outpatient care services and assistance´s inefficiency, that result in noncompliance with treatment, including medication treatment. This scenario favors social isolation and contributes to that, in times of crisis, when there is no possibility of acceptance of suffering in the service, the hospital becomes the most used tool by the patient. Thus, the coexistence of opposing models, hospital and community, produces a new phenomenon, which, however, reproduces the old one: the psychiatric readmission that leads to the repetition of the institutionalization. Accordingly, the psychiatric readmission, as current phenomenon, reveals the unfinished and unbound process of the Psychiatric Reform, and confirms that the effective deinstitutionalization occurs only with proper replacement of the hospital model for the Psychosocial Care model.

Heart failure (HF) is a serious, life limiting chronic illness and is the most common cause of <30-day hospital readmission, which is costly both in its profound negative impact on patient mortality and quality of life, and in economics. Limited access to care in rural communities increases the prevalence of hospitalizations for heart disease in rural areas. The aims of this project using data mined from Arizona Health Sciences Center Clinical Research Data Warehouse, are to define clinical events (fever, pain, changes in respiratory status, change in level of consciousness, changes in output, bleeding, and suicide ideation) for patients with heart failure, and determine what assessment values are for chronically ill patients and compare to "normal" assessment values for non-chronically ill patients. A literature review was completed to determine how to define clinical events for chronically ill patients with HF, and how decision making is used at home to manage chronic illness. Assessment value data was mined from the clinical research data warehouse and compared to “normal” assessment values, with identification of associations between clinical events and action taken in the hospital. The project results support that there are differences in "normal" assessment values for fever, pain, and change in respiratory status between chronically ill patients with HF, and non-chronically ill patients; there was insufficient data to define bleeding, change in output, or suicide ideation. Impacts to care include earlier recognition of worsening HF symptoms that could result in an earlier call or visit to primary care provider forestalling the need for emergent care and hospital readmission. Application of the mined clinical may inform development of evidenced-based algorithm to guide decision-making at home, and it may also provide the foundation for the development of a tool for patient use to prevent <30-day hospital readmission.

Thesis (M. Cur.) --University of Limpopo, 2015 / Background: Re-admission is a common problem encountered in psychiatric care. Re-admissions are often, but not always, related to a problem inadequately resolved in the prior hospitalization. A better understanding of factors leading multiple psychiatric admissions is needed. Such knowledge can help planners to set priorities and to make appropriate services and resources available to mental health care users and their families after hospital discharge. Objective: The purpose of this study was to explore the factors leading to re-admission of mental health care users at the Thabamoopo Psychiatric Hospital, Limpopo Province. Methodology: A qualitative phenomenological research approach was used to explore the factors leading to readmission of mental health care users. Purposive sampling was used to select participants of the study at the Thabamoopo Hospital. Twelve one-on-one semi-structured interviews were conducted. Ethical clearance was granted by the Medunsa Research Ethics Committee and permission to collect data was granted by the Limpopo Department of Health. The data were analysed through Tesch’s method of analysis. Results: The research findings indicate that the use of substances, non-adherence to psychiatric medication, the nature of the illness and social problems contributes to readmission of mental health care users. Conclusion and recommendations: In order to deal with factors related to re-admission of mental health care users, the mental health care practitioners, mental health care users and their families must be involved and work together.

Approximately 20% of congestive heart failure (CHF) patients are readmitted within 30 days of hospital discharge, a rate which may be affected by in-hospital and post-discharge care. Reducing this rate is important to hospitals, both to improve outcomes and to avoid reductions in Medicare reimbursement. Assessing outcomes within a short post-discharge window best measures the impact of the care, planning, and followup of that admission; but most research on the effects of changes in CHF care has measured outcomes over periods longer than 30 days, adding the unpredictable long-term course of CHF to the factors affecting the outcome. As well, almost no studies to date have included the appreciable effects of CHF comorbidities in their analyses. This study addresses these needs by measuring rates of 30-day all-cause readmission, and by adjusting for comorbidities and demographic factors in our analysis. We hypothesize that an improved CHF care protocol including both in-hospital and post-discharge components will reduce the risk of readmission, and may alter the rate of change of that risk. We have analyzed as an interrupted time series data on 2764 discharges of CHF patients from a hospital that implemented such a change to assess the effect of the new protocol on the readmission risk and on the trend in that risk, comparing outcomes in the 22 months preceding introduction of the new protocol to those in the first 31 months of full implementation. Using multiple logistic regression, we have tested for an association between the new protocol and both the unadjusted risk of readmission, and that risk in a model including comorbidities and demographic factors as covariates. Neither model found a statistically significant association between introduction of the protocol and log-odds of readmission (unadjusted p = 0.847, adjusted p = 0.755) or between introduction of the protocol and change in risk of readmission over time (unadjusted p = 0.437, adjusted p = 0.313). These results, in comparison with other published results, can clarify what changes to care protocols have been shown to be effective. Further, post hoc power analysis of this study can inform study design for further research.

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