The growth of network and distributed technologies in flight test instrumentation (FTI) has provided the benefits of flexibility, scalability, and compatibility with prevalent computing capabilities. However, to achieve these capabilities, the complexity of each piece of FTI and the overall system has increased dramatically. Even with systems composed of equipment from a single vendor, it is important to have management systems that provide the flexibility to adapt quickly to various system configurations and present unified information to the flight test users. The growth of network technologies and then standardized approaches such as iNET standards becoming accepted IRIG 106 standards is leading to the growth of multi-vendor systems. These multi-vendor systems further increase the need for rapidly reconfigurable management systems. This paper describes a constraints engine we have developed to enable flexible system management systems and reflects on how these techniques have been used successfully in the iNET System Manager.

SOUSA, Solange Damasceno. Proteômica do fluido da Rete Testis de carneiros Morada Nova. 2015. 133 f. : Dissertação (Mestrado) - Universidade Federal do Ceará, Centro de Ciências, Departamento de Zootecnia, Programa de Pós-Graduação em Zootecnia. Fortaleza-CE, 2015. / Submitted by Eric Santiago (erichhcl@gmail.com) on 2016-08-10T12:26:45Z No. of bitstreams: 1 2015_dis_sdsousa.pdf: 3355993 bytes, checksum: 3f9c9ea989725756a91c3d6679b0614a (MD5) / Approved for entry into archive by Nádja Goes (nmoraissoares@gmail.com) on 2016-08-10T15:18:50Z (GMT) No. of bitstreams: 1 2015_dis_sdsousa.pdf: 3355993 bytes, checksum: 3f9c9ea989725756a91c3d6679b0614a (MD5) / Made available in DSpace on 2016-08-10T15:18:50Z (GMT). No. of bitstreams: 1 2015_dis_sdsousa.pdf: 3355993 bytes, checksum: 3f9c9ea989725756a91c3d6679b0614a (MD5) Previous issue date: 2015 / The aim of the study was to identify and characterize the proteins of the rete testis fluid from Morada Nova rams. The testicles, obtained from six slaughtered Morada Nova rams, were immediately dissected. The head of the epididymis was separated to gain access to the efferent ducts. The fluid from the efferent ducts was obtained by testis massage. Thereafter, the fluid was centrifuged to remove cell debris and sperm. Proteins were precipitated with acetone at -20°C and quantified by the Bradford assay. Each sample (400 µg) was focused in strips of 13 cm (pH 4-7) and the second dimension was conducted on SDS-PAGE 15%. The gels were scanned with an ImageScanner II (GE Lifesciences, USA) and analyzed using the PDQuest® version 8.0.1 (Bio-Rad Laboratories, USA). Spots detected after PDQuest analysis of 2-D maps were cut from gels and submitted to trypsin digestion. Proteins were identified using tandem mass spectrometry. Protein information obtained by MASCOT was analyzed using the software tool for searching annotations of proteins (STRAP). Protein-protein interaction networks were obtained from STRING version 9.0 database. In the gels were detected 227 ± 32.1 spots (mean ± SD), where 51% of the proteins were found above 40 kDa, corresponding to 65% of the intensity of all spots detected. Based on gene ontology analysis, the most common biological processes associated with proteins from rete testis fluid were regulation (24.28%) and cellular process (23.27%). Binding (27.42%) and catalytic activity (19.30%) corresponded to the most frequent molecular functions for those proteins. The most intensely expressed proteins were: albumin, clusterin, serotransferrin, immunoglobulin gamma-1 chain and alpha-2-HS-glycoprotein. The rete testis fluid has a large quantity of proteins related to the spermatogenesis. This feature is important in view of the fact that these molecules contribute to the development of the germ cells, as a result of the transport and conversion of substances required to the production of male gametes. / O objetivo do estudo foi identificar e caracterizar as proteínas do fluido da rete testis de carneiros Morada Nova. Os testículos, obtidos de seis carneiros Morada Nova abatidos, foram imediatamente dissecados. A cabeça do epidídimo foi separada para ter acesso aos ductos eferentes. O fluido oriundo dos ductos eferentes foi obtido por massagem do testículo. Posteriormente, o fluido foi centrifugado para remoção dos debris celulares e espermatozoides. As proteínas foram precipitadas com acetona a -20°C e quantificadas pelo método de Bradford. Cada amostra (400 μg) foi focalizada em tiras de 13 cm (pH 4-7) e a segunda dimensão foi realizada em SDS-PAGE a 15%. Os géis obtidos foram escaneados com um ImageScanner II (GE Lifesciences, EUA) e analisados utilizando o aplicativo PDQuest® versão 8.0.1 (Bio-Rad Laboratories, EUA). Os spots detectados após a análise dos mapas 2-D no PDQuest foram cortados dos géis e submetidos a digestão com tripsina. As proteínas foram identificadas por espectrometria de massa em tandem. A informação sobre a proteína adquirida pela busca no MASCOT foi analisada através da utilização do programa para anotações de proteínas (STRAP). Redes de interação proteína-proteína foram obtidas a partir do banco de dados STRING versão 9.0. Nos géis foram detectados em média 227 ± 32,1 spots, onde 51% das proteínas se encontraram acima de 40 kDa representando 65% da intensidade de todos os spots detectados nos géis. Com base na análise da ontologia gênica, os processos biológicos mais comuns associados às proteínas do fluido rete testis foram regulação (24,28%) e processos celulares (23,27%). Ligação (27,42%) e a atividade catalítica (19,30%) corresponderam às funções moleculares mais frequentes. As proteínas mais intensamente expressas foram: albumina, clusterina, serotransferrina, imunoglobulina gama-1 e alfa-2-HS-glicoproteína. A maioria das proteínas identificadas desempenha importantes papéis nos processos de espermatogênese, proteção espermática, motilidade, capacitação e reação acrossômica. O fluido da rete testis possui várias proteínas envolvidas na espermatogênese, o que representa um importante fator, uma vez que estas moléculas contribuem para o desenvolvimento das células germinativas, participando no transporte e conversão de substâncias requeridas para a produção dos gametas masculinos.

FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico / O objetivo do estudo foi identificar e caracterizar as proteÃnas do fluido da rete testis de carneiros Morada Nova. Os testÃculos, obtidos de seis carneiros Morada Nova abatidos, foram imediatamente dissecados. A cabeÃa do epidÃdimo foi separada para ter acesso aos ductos eferentes. O fluido oriundo dos ductos eferentes foi obtido por massagem do testÃculo. Posteriormente, o fluido foi centrifugado para remoÃÃo dos debris celulares e espermatozoides. As proteÃnas foram precipitadas com acetona a -20ÂC e quantificadas pelo mÃtodo de Bradford. Cada amostra (400 μg) foi focalizada em tiras de 13 cm (pH 4-7) e a segunda dimensÃo foi realizada em SDS-PAGE a 15%. Os gÃis obtidos foram escaneados com um ImageScanner II (GE Lifesciences, EUA) e analisados utilizando o aplicativo PDQuest versÃo 8.0.1 (Bio-Rad Laboratories, EUA). Os spots detectados apÃs a anÃlise dos mapas 2-D no PDQuest foram cortados dos gÃis e submetidos a digestÃo com tripsina. As proteÃnas foram identificadas por espectrometria de massa em tandem. A informaÃÃo sobre a proteÃna adquirida pela busca no MASCOT foi analisada atravÃs da utilizaÃÃo do programa para anotaÃÃes de proteÃnas (STRAP). Redes de interaÃÃo proteÃna-proteÃna foram obtidas a partir do banco de dados STRING versÃo 9.0. Nos gÃis foram detectados em mÃdia 227  32,1 spots, onde 51% das proteÃnas se encontraram acima de 40 kDa representando 65% da intensidade de todos os spots detectados nos gÃis. Com base na anÃlise da ontologia gÃnica, os processos biolÃgicos mais comuns associados Ãs proteÃnas do fluido rete testis foram regulaÃÃo (24,28%) e processos celulares (23,27%). LigaÃÃo (27,42%) e a atividade catalÃtica (19,30%) corresponderam Ãs funÃÃes moleculares mais frequentes. As proteÃnas mais intensamente expressas foram: albumina, clusterina, serotransferrina, imunoglobulina gama-1 e alfa-2-HS-glicoproteÃna. A maioria das proteÃnas identificadas desempenha importantes papÃis nos processos de espermatogÃnese, proteÃÃo espermÃtica, motilidade, capacitaÃÃo e reaÃÃo acrossÃmica. O fluido da rete testis possui vÃrias proteÃnas envolvidas na espermatogÃnese, o que representa um importante fator, uma vez que estas molÃculas contribuem para o desenvolvimento das cÃlulas germinativas, participando no transporte e conversÃo de substÃncias requeridas para a produÃÃo dos gametas masculinos. / The aim of the study was to identify and characterize the proteins of the rete testis fluid from Morada Nova rams. The testicles, obtained from six slaughtered Morada Nova rams, were immediately dissected. The head of the epididymis was separated to gain access to the efferent ducts. The fluid from the efferent ducts was obtained by testis massage. Thereafter, the fluid was centrifuged to remove cell debris and sperm. Proteins were precipitated with acetone at -20ÂC and quantified by the Bradford assay. Each sample (400 Âg) was focused in strips of 13 cm (pH 4-7) and the second dimension was conducted on SDS-PAGE 15%. The gels were scanned with an ImageScanner II (GE Lifesciences, USA) and analyzed using the PDQuest version 8.0.1 (Bio-Rad Laboratories, USA). Spots detected after PDQuest analysis of 2-D maps were cut from gels and submitted to trypsin digestion. Proteins were identified using tandem mass spectrometry. Protein information obtained by MASCOT was analyzed using the software tool for searching annotations of proteins (STRAP). Protein-protein interaction networks were obtained from STRING version 9.0 database. In the gels were detected 227  32.1 spots (mean  SD), where 51% of the proteins were found above 40 kDa, corresponding to 65% of the intensity of all spots detected. Based on gene ontology analysis, the most common biological processes associated with proteins from rete testis fluid were regulation (24.28%) and cellular process (23.27%). Binding (27.42%) and catalytic activity (19.30%) corresponded to the most frequent molecular functions for those proteins. The most intensely expressed proteins were: albumin, clusterin, serotransferrin, immunoglobulin gamma-1 chain and alpha-2-HS-glycoprotein. The rete testis fluid has a large quantity of proteins related to the spermatogenesis. This feature is important in view of the fact that these molecules contribute to the development of the germ cells, as a result of the transport and conversion of substances required to the production of male gametes.

Rete Mirabile is my new installation piece combining scientific principles with live computer generated music. The title is a Latin term meaning "Wonderful Net," which I use to refer to the highly convoluted network of biological data that drives my installation. The sonification of data, computer modeling of biological processes, kinetic sculptures, and user interactivity are central parts of the installation. The paper is organized as follows: First, brief history of the forerunners that inspired my work is given. This includes a short discussion on how John Cage and David Tudor influenced current artists works, and how those works have influenced my own work. Then I review current installation works that share similarities with my own. Finally, a detailed discussion and analysis of the construction and function concludes the paper.

Diamond is a SPARQL query engine for linked data. Linked data is a sub-topic of the Semantic Web where data is represented as a labeled directed graph using the Resource Description Framework (RDF), a conceptual data model for web resources, to affect a web-wide interconnected, distributed labeled graph. SPARQL graph patterns entail portions of this distributed graph. Diamond compiles SPARQL queries into a physical query plan based on a set of newly defined operators that implement a new variant of the Rete match, a well known artificial intelligence (AI) algorithm used for complex pattern-matching problems. / text

Il legislatore, con la previsione di cui al comma 4- ter dell'art. 3 del d.l. 10 febbraio 2009, n. 5, convertito con modificazioni dalla legge 9 aprile 2009, n. 33, e sostituito dall'art. 42, comma 2-bis del d.l. 31 maggio 2010 n. 78, ha introdotto una nuova figura contrattuale avente la chiara finalità di favorire lo sviluppo dell'economia del paese. Il lavoro, partendo da una ricognizione empirica dei singoli contratti effettivamente stipulati, intende procedere ad una ricostruzione economicagiuridico del nuovo strumento della rete contrattuale tra imprese, fondandola sulla possibilità di costituire rapporti orizzontali tra partecipanti, che il legislatore ha espressamente previsto nella disciplina di legge, intendendosi tali tutte le obbligazioni che vengono assunte, al fine di realizzare il «programma comune di rete», da parte di uno o più degli aderenti nei confronti e a favore di uno o più degli altri partecipanti. Tale ricerca, anzitutto, verifica nel primo capitolo, la rilevanza che i rapporti orizzontali costituibili all'interno del nuovo contratto possono avere nel raggiungimento dei fini di politica economica perseguiti dalla norma: a tal fine si procede, dunque, sinteticamente all'analisi delle caratteristiche del sistema economico italiano, individuando i concetti economici e giuridici di “distretto” e “rete fattuale di imprese” ed evidenziando come gli stessi siano fondati su relazioni economiche recepibili in forma di rapporti orizzontali tra partecipanti al nuovo strumento contrattuale e si accerta che la potenzialità/effettività/volontariatetà di questi ultimi permette di tracciare il confine tra le stesse figure. La ricerca prosegue, poi, a verificare se la previsione di tali rapporti orizzontali tra i partecipanti - permettendo, al nuovo strumento contrattuale, di recepire a livello giuiridico la effettiva struttura economica delle modalità produttive a rete del nostro paese (distretti e reti fattuali d'impresa) - sia rilevante rispetto alla politica economica legislativa ed individua quali vantaggi ciò possa generare a livello di economie esterne alle singole imprese aderenti, ma interne alla rete stessa (in particolare rispetto alla finanziabilità delle imprese partecipanti alle reti). Appurato che, almeno in via teorica, la possibilità di costituire rapporti orizzontali tra partecipanti può essere utile nel perseguimento della finalità di politica economica, si procede a comprendere quanto tale previsione abbia comportato nella strutturazione giuridica del contratto. Nel secondo capitolo, riprendendo l'analisi delle attuali categorie contrattuali e considerata anche la loro evoluzione, si ricostruisce, da un punto di vista dogmatico-giuridico, il contratto di rete e, analizzando ed escludendo quelle teorie che attribuiscono allo stesso una natura “ibrida” ed una sua possibile riconducibilità ai contratti di scambio, si evidenziano tutte le motivazioni che portano a ritenerlo sempre e comunque un contratto associativo. Dato atto di ciò, ripercorrendo le caratteristiche di questa categoria contrattuale, nella ricerca si procede ad evidenziare le problematiche conseguenti all'applicazione delle norme di cui agli artt. 1420, 1446, 1459 e 1466 c.c., espressamente richiamate dal legislatore: tali norme, nate per disciplinare contratti che prevedono esclusivamente rapporti verticali tra l'ente e gli associati (caratterizzati, pertanto, esclusivamente da un “sinallagma per partecipazione”) appaiono non del tutto adeguate a regolare un contratto ove, in presenza di rapporti orizzontali, sussiste anche una sinallagmaticità “per corrispettività”, la quale rende necessaria una riconsiderazione dei criteri interpretativi delle suddette norme, che permetta di offrire adeguate tutele ad ogni interesse contrattuale. La terza parte analizza se, all'interno della categoria dei contratti associativi, la rete contrattuale sia un contratto del tutto nuovo ovvero se sia riconducibile a preesistenti figure e, nel caso, entro quali limiti: nel procedere a tale esame, tenendo conto che il dettato legislativo contiene un espresso riferimento ad alcune norme che disciplinano il fondo comune consortile, si verifica se sia giustificabile una riconduzione della rete contrattuale all'interno della generale tipologia consortile, evidenziando, peraltro, che i rapporti orizzontali permettono di qualificarla come nuova tipologia consortile, che offre strumenti ulteriori rispetto a quelle preesistenti e che la presenza di tali rapporti è di ostacolo alla possibilità che la rete possa assumere forme societarie. La conclusione del lavoro evidenzia che il legislatore, con l'introduzione del contratto di rete, ha introdotto una innovativa species associativa, riconducibile al genus consortile, consentendo, per la prima volta, che la strutturazione di un tale tipologia di contratto possa avvenire non solo attraverso gli abituali rapporti verticali, che obbligano i partecipanti nei confronti dell'ente, ma, pure, attraverso rapporti orizzontali, i quali concorrono, insieme con gli ordinari rapporti verticali, a rendere possibile, anche attraverso la combinazione delle attività dei partecipanti e lo scambio tra di essi sia di prestazioni sia di risorse, la realizzazione dell'attività volta al perseguimento dello scopo comune del contratto in questione. / The Legislator, with the provision of paragraph 4-ter art. 3 of d.l. February 10, 2009, No 5, converted with some amendments by the law “April 9, 2009, No 33”, and replaced by. Art.42, paragraph 2-bis of the d.l. nr. 78 of May 31st 2010, has introduced a new figure of contract with the clear aim of promoting the development of the Country. The work, starting from an empirical survey of individual contracts actually concluded, intends to define under new legal and economic background the new instrument of the network contract between companies, establishing the possibility of establishing horizontal relations between participants, that the Legislator has expressly provided for in the common law, meaning such network as all the obbligations that are taken in order to realize the "joint network program”, by one or more of its members against and in favor of one or more other participants. This research, first of all, shows in the first chapter, the relevance that horizontal relations established within the new contract may have in achieving the goals of economic policy pursued by the law: to this end we proceed, therefore, in a brief analysis of the characteristics the Italian economic system, identifying the economic and legal concepts of "district" and "factual business network" and pointing out that the same are based on economic relations that can be represented in the form of horizontal relations between participants in the new contractual instrument. This research verifies that the potentiality/ effectiveness/volontariaty of the latter allows you to draw the line between the same figures. The research continues, then, to verify if the prediction of such horizontal relationships among the participants - allowing, to this new type of contract, to transpose in a giuridical way the actual economic structure of our country's production structure (business districts and de-facto networks of compaies) - is material in relation to legislative economical policy and identifies what benefits it may be generated in terms of external economies at the level of individual member company, but internal to the network itself (in particular with respect to the improved credit eligibility of the firms participating in networks). Having verified that, at least in theory, the possibility of establishing horizontal relations between participants can be helpful in pursuing the aim of economic policy, we proceed to understand how this provision has resulted in the legal structuring of the contract. In the second chapter, continuing the analysis of the current contract categories and considered also their evolution, is defined, from a legal-dogmatic point of view, the “network contract”, and analyzing and excluding those theories which attribute to it an “hybrid” nature and its possible link to exchange contracts, the research highlights all the reasons that lead us to conclude that it has always to be considered an associative contract. Because of this act, recapitulating the features of this contract category, the research proceeds to highlight the problems connected to application of Articles. 1420, 1446, 1459 and 1466 cc, expressly cited by the Legislator: such articles, created to regulate contracts involving only vertical relationships between the “entity” and the “associates” are not the entirely adequate to set a contract with horizontal relations, which requires a reconsideration of the criteria for interpretation of those rules, which allows to offer adequate protection to any contractual interest. The third part analyzes whether, within the category of associative contracts, the network contract is a new kind of contract or whether it is reconductable to existing contractual types and, if so, to what extent: in making such examination, taking into account that the legislation contains a specific reference to certain rules governing the mutual fund, it is verified if the network contract can be justified within the general type of consortium contract, emphasizing, however, that the horizontal relationship qualify it as a new type of consortium, which offers more than existing tools and that the presence of such relationships is an obstacle to the possibility that the network contract can assume societary forms. The conclusion of this paper stresses that the Legislator, with the introduction of the network contract, has introduced an innovative associative species, reconductable to that of a consortium, allowing, for the first time, that the structuring of such a type of contract can occur not only through the usual vertical relationships, which formally link the participants with the Entity, but also through horizontal relationships, which contribute, together with the ordinary vertical relationships, to make possible, through the combination of the activities of participants and the exchange between them of both performances or resources, the implementation of activities aimed at achieving the common purpose of the contract in question

Retia mirabile of the eel swimbladder were exsanguinated, perfusion‐fixed and subjected to prolonged osmication. They were then microdissected by ultrasonication which delaminated the capillary bed along planes which revealed the surfaces of arterial and venous capillaries. This procedure resulted in cleaned capillary surfaces largely free of connective tissue elements and basement membrane material. The arterial capillary segments were heavily invested with pericytes characterized by plump cell bodies containing nuclei and an extensive system of processes encircling the capillary wall. These processes exhibited a hierarchical organization consisting of primary, secondary, and tertiary elements arising roughly at right angles to each other. Primary and secondary processes exhibited frequent anastomoses and resulted in cytoplasmic continuity between adjacent cell bodies. Processes were also observed to form connections between pericytes on adjacent capillaries. These observations are evidence for the existence of a pericapillary syncytium in which cell bodies may be connected in series and in parallel throughout the arterial capillary bed. This syncytial organization would provide for a coordinated and global contractile response of pericytes to vasoactive hormones and other effectors. It may also provide for synchrony of nuclear division during developmental spread of pericytes along capillary surfaces.

Situation recognition is a process with the goal of identifying a priori defined situations in a flow of data and information. The purpose is to aid decision makers with focusing on relevant information by filtering out situations of interest. This is an increasingly important and non trivial problem to solve since the amount of information in various decision making situations constantly grow. Situation recognition thus addresses the information gap, i.e. the problem of finding the correct information at the correct time. Interesting situations may also evolve over time and they may consist of multiple participating objects and their actions. This makes the problem even more complex to solve. This thesis explores situation recognition and provides a conceptualization and a definition of the problem, which allow for situations of partial temporal definition to be described. The thesis then focuses on investigating how Petri nets can be used for recognising situations. Existing Petri net based approaches for recognition have some limitations when it comes to fulfilling requirements that can be put on solutions to the situation recognition problem. An extended Petri net based technique that addresses these limitations is therefore introduced. It is shown that this technique can be as efficient as a rule based techniques using the Rete algorithm with extensions for explicitly representing temporal constraints. Such techniques are known to be efficient; hence, the Petri net based technique is efficient too. The thesis also looks at the problem of learning Petri net situation templates using genetic algorithms. Results points towards complex dynamic genome representations as being more suited for learning complex concepts, since these allow for promising solutions to be found more quickly compared with classical bit string based representations. In conclusion, the extended Petri net based technique is argued to offer a viable approach for situation recognition since it: (1) can achieve good recognition performance, (2) is efficient with respect to time, (3) allows for manually constructed situation templates to be improved and (4) can be used with real world data to find real world situations. / <p>Anders Dahlbom is also affiliated to Skövde Artificial Intelligence Lab (SAIL), Information Fusion Research Program, Högskolan i Skövde</p>

No description available.

La pratica dei network contracts ha ricevuto una notevole attenzione da parte degli studiosi. In questa tesi viene presa in considerazione una forma caratteristica di network contract, nota come “contratto di rete”, che è stato recentemente introdotto nell’ordinamento italiano. Dopo aver fornito una rassegna dei principali contributi della letteratura IMP con riferimento alle relazioni reticolari in contesti business-to-business, vengono discusse le implicazioni teoriche di differenti strutture della rete sulle perfomance della rete stessa. Viene inoltre sviluppata un’analisi empirica basata su diversi “contratti di rete”. Mostriamo che le reti in cui le imprese producono prodotti differenziati, in cui le imprese sono collocate ad una certa distanza geografica, dove ogni impresa percepisce se stessa come cruciale per la rete stessa, e dove il numero delle imprese è sufficientemente basso, ottengono un risultato mediamente superiore rispetto alle reti aventi caratteristiche opposte. Inoltre mostriamo come le reti in cui il potere è suddiviso in modo equo tra le imprese partecipanti (reti simmetriche) ottengono una performance migliore rispetto alle reti in cui alcune imprese hanno un ruolo dominante (reti asimmetriche). / Network contract is a business practice which has received a lot of attention by scholars. In this thesis we consider a peculiar form of network contract named “contratto di rete”, which has been recently introduced by the Italian legislator. After providing a selective survey of the main contributions from the IMP tradition regarding network relationships in business-to-business contexts, we discuss the theoretical implications of different network structures on the performance of the networks. We also develop an empirical analysis based on several “contratti di rete”. We show that the networks where the firms produce different goods, where the firms are not located close to each other, where each firm perceives itself as crucial for the network, and where the number of firms is low enough, get a better outcome than the networks showing the opposite characteristics. Furthermore, we show that the networks where the power is shared equally among the firms (symmetric networks) perform better than the networks where some firms play a dominant role (asymmetric networks).