Flat plate systems are constructed with slabs directly supported on columns. Since there are no beams in the system, the behavior of connections between the slabs and columns play a crucial role. Due to the sudden and brittle nature of punching shear failures, slab-column connection design must be conducted with proper safety precautions. The first part of this study aims to evaluate the safety level of different design expressions in the codes. Fir this purpose, the ability of ACI 318-11, TS-500 and Eurocode-2 to estimate punching shear strength was examined in light of experimental results compiled from previous research. Interior and exterior connections were examined in the course of the study. In the second part of the study, beam and shell models were calibrated to simulate the load-deformation response of interior slab-column connections in light of experimental results. In the final part of this thesis, a typical floor plan of a flat plate system was analyzed to investigate the possibility of a progressivefailure mechanism after punching failure takes place at a slab-column connection. Minimum post-punching capacity required to avoid progressive punching failure in a floor was estimated. It is believed that, the results of this study can be helpful in guiding engineers in understanding the safety inherent in punching shear design expressions and to take necessary precautions against progressive collapse.

Railway track stiffness (vertical track load divided by track deflection) is a basic parameter oftrack design which influences the bearing capacity, the dynamic behaviour of passing vehiclesand, in particular, track geometry quality and the life of track components. Track stiffness is abroad topic and in this thesis some aspects are treated comprehensively. In the introductionpart of the thesis, track stiffness and track stiffness measurements are put in their propercontext of track maintenance and condition assessment. The first aspect is measurement of track stiffness. During the course of this project, Banverkethas developed a new device for measurement of dynamic track stiffness called RSMV(Rolling Stiffness Measurement Vehicle). The RSMV is capable of exciting the trackdynamically through two oscillating masses above one wheelset. The dynamic stiffness is acomplex-valued quantity where magnitude is the direct relation between applied load anddeflection (kN/mm) and phase is a measure of deflection-delay by comparison with force. Thephase has partial relationship with damping properties and ground vibration. The RSMVrepeatability is convincing and both overall measurements at higher speeds (up to 50 km/h)and detailed investigations (below 10 km/h) can be performed. The measurement systemdevelopment is described in Paper A and B. The second aspect is evaluation of track stiffness measurements along the track from a trackengineering perspective. Actual values of stiffness as well as variations along the track areimportant, but cannot always answer maintenance and design related questions alone. InPaper D track stiffness is studied in combination with measurements of track geometryquality (longitudinal level) and ground penetrating radar (GPR). The different measurementsare complementary and a more reliable condition assessment is possible by the combinedanalysis. The relation between soft soils and dynamic track stiffness measurements is studiedin Paper C. Soft soils are easily found and quantified by stiffness measurements, in particularif the soft layer is in the upper part of the substructure. There are also possibilities to directlyrelate substructure properties to track stiffness measurements. Environmental vibrations areoften related to soft soils and partly covered in Paper C. One explanation of the excitationmechanism of train induced environmental vibrations is short waved irregular supportconditions. This is described in Paper E, where track stiffness was evinced to have normalvariations of 2 – 10 % between adjacent sleepers and variations up to 30 % were found. Anindicative way of finding irregular support conditions is by means of filtering longitudinallevel, which is also described in the paper. Train-track interaction simulation is used in PaperH to study track stiffness influence on track performance. Various parameters of trackperformance are considered, e.g. rail sectional moment, rail displacement, forces at wheel-railinterface and on sleepers, and vehicle accelerations. Determining optimal track stiffness froman engineering perspective is an important task as it impacts all listed parameters. The third aspect, efficient maintenance, is only partially covered. As track stiffness relates toother condition data when studied from a maintenance perspective, vertical geometricaldefects (longitudinal level and corrugation/roughness) are studied in paper F. The generalmagnitude dependency of wavelength is revealed and ways of handling this in conditionassessment are proposed. Also a methodology for automated analysis of a large set ofcondition data is proposed in Paper G. A case study where dynamic track stiffness,longitudinal level and ground penetrating radar are considered manifests the importance oftrack stiffness measurements, particularly for soil/embankment related issues. / QC 20100623

The dynamic behaviour in the audible frequency range of magneto-sensitive (MS) rubber is the focus of this thesis consisting of five papers A-E. Paper A presents results drawn from experiments on samples subjected to different constant shear strains over varying frequencies and magnetic fields. Main features observed are the existence of an amplitude dependence of the shear modulus referred to as the Fletcher-Gent effect for even small displacements, and the appearance of large MS effects. These results are subsequently used in Paper B and C to model two magneto-sensitive rubber isolators, serving to demonstrate how, effectively, by means of MS rubber, these can be readily improved. The first model calculates the transfer stiffness of a torsionally excited isolator, and the second one, the energy flow into the foundation for a bushing inserted between a vibrating mass and an infinite plate. In both examples, notable improvements in isolation are obtainable. Paper D presents a non-linear constitutive model of MS rubber in the audible frequency range. Characteristics inherent to magneto-sensitive rubber within this dynamic regime are defined: magnetic sensitivity, amplitude dependence, elasticity and viscoelasticity. A very good agreement with experimental values is obtained. In Paper E, the magneto-sensitive rubber bushing stiffness for varying degrees of magnetization is predicted by incorporating the non-linear magneto-sensitive audio frequency rubber model developed in Paper D, into an effective engineering formula for the torsional stiffness of a rubber bushing. The results predict, and clearly display, the possibility of controlling over a large range through the application of a magnetic field, the magneto-sensitive rubber bushing stiffness. / QC 20100816

Estimation of elastic anisotropy, which is usually caused by rock fabrics and mineral orientation, has an important role in exploration seismology and better understanding of crustal seismic reflections. If not properly taken care of during processing steps, it may lead to wrong interpretation or distorted seismic image. In this thesis, a state-of-the-art under the development Laser Doppler Interferometer (LDI) device is used to measure phase velocities on the surface of rock samples from a major deformation zone (Österbybruk Deformation Zone) in the Bergslagen region of eastern Sweden. Then, a general inversion code is deployed to invert measured phase velocities to obtain full elastic stiffness tensors of two samples from the major deformation zone in the study area. At the end, results are used to correct for the anisotropy effects using three dimensionless Tsvankin's parameters and a non-hyperbolic moveout equation. The resulting stacked section shows partial reflection improvement of the deformation zone compared with the isotropic processing section. This suggests that rock anisotropy may also contribute to the generation of reflections from the deformation zones in the study area but requires further investigations.

The field of inverse problems is an area in applied mathematics that is of great importance in several scientific and industrial applications. Since an inverse problem is typically founded on non-linear and ill-posed models it is a very difficult problem to solve. To find a regularized solution it is crucial to have a priori information about the solution. Therefore, general theories are not sufficient considering new applications. In this thesis we consider the inverse problem to determine the beam bending stiffness from measurements of the transverse dynamic displacement. Of special interest is to localize parts with reduced bending stiffness. Driven by requirements in the wood-industry it is not enough considering time-efficient algorithms, the models must also be adapted to manage extremely short calculation times. For the developing of efficient methods inverse problems based on the fourth order Euler-Bernoulli beam equation and the second order string equation are studied. Important results are the transformation of a nonlinear regularization problem to a linear one and a convex procedure for finding parts with reduced bending stiffness.

Loading can dramatically reduce the vibratory displacement and the operating frequency in vibrotactile systems implementations that use an eccentric mass motor, but this phenomenon is not well modeled or understood. In this work, we derive a dynamic model of this phenomenon and implement a system for measuring stiffness and grip force that take advantage of this phenomenon. The system is based on a non-interposed sensing approach using an eccentric mass dc motor mounted on the outside of the index finger. If the device were to be worn as a wearable sensor, it could be embedded in a ring. The basic idea is that a person could wear the ring sensor and through it measure the stiffness and grip force when squeezing various objects, without requiring the ring sensor to actually contact the object. The results show that grip force and muscle stiffness vary with motor velocity (operating frequency) and thus that the measurement of velocity can be used to infer grip force and stiffness. With the validated model, we also developed an optimization routine which computes the best design parameters for inertial load and voltage to maximize the phenomenon. This provided insight into the optimal parameters that should be used in an actual ring sensor design to achieve high performance by attaining a good trade-off between high sensor sensitivity and low level of vibration.

Smoking and environmental tobacco smoke (ETS) exposure are major risk factors for cardiovascular disease (CVD), although the exact components and pathophysiological mechanisms responsible for this association remain unclear. Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BaP), are ubiquitous environmental contaminants that form during organic material combustion and are thus found in cigarette smoke, vehicle exhaust particles, and air pollution. We hypothesize that PAHs are key agents responsible for mediating the cigarette smoke effects in the cardiovascular system, including increased oxidative stress, inflammation, and arterial stiffness.<p> Arterial stiffness is a powerful, independent predictor of cardiovascular risk and is regulated, in part, by vasoactive mediators derived from the endothelium. The first objective of this project was to determine whether pulse wave dP/dt collected from radiotelemetry-implanted rats is a reliable indicator of changes in arterial stiffness following administration of vasoactive drugs or acute ETS exposure. Anaesthetized rats were administered a single dose of saline (vehicle control), acetylcholine, norepinephrine, and N(G)-nitro-L-arginine methyl ester (L-NAME) via the tail vein, allowing a washout period between injections. Acetylcholine decreased and norepinephrine increased dP/dt compared to saline vehicle. Injection of the nitric oxide (NO) synthase inhibitor L-NAME decreased plasma nitrate/nitrite (NOx), but transiently increased dP/dt. For the ETS experiment, rats were exposed for one hour to sham, low dose ETS, or high dose ETS. Exposure to ETS did not significantly alter dP/dt or plasma endothelin-1 (ET-1) levels, but increased plasma NOx levels at the high ETS exposure and increased plasma nitrotyrosine levels in both ETS groups. In conclusion, acute changes in NO production via acetylcholine or L-NAME alter the arterial pulse wave dP/dt consistently with the predicted changes in arterial stiffness. Although acute ETS appears to biologically inactivate NO, a concomitant increase in NO production at the high ETS exposure may explain why ETS did not acutely alter dP/dt.<p> The second objective of this project was to compare the effects of subchronic ETS and BaP exposure on circadian blood pressure patterns, arterial stiffness, and possible sources of oxidative stress in radiotelemetry-implanted rats. Pulse wave dP/dt was used as an indicator of arterial stiffness, and was compared to both structural (wall thickness) and functional (NO production and bioactivity, ET-1 levels) features of the arterial wall. In addition, histology of lung, heart, and liver were examined as well as pulmonary and hepatic detoxifying enzyme activity (cytochrome P450 specifically CYP1A1). Daily ETS exposure for 28 days altered the circadian pattern of heart rate and blood pressure in rats, with a loss in the normal dipping pattern of blood pressure during sleep. Subchronic ETS exposure also increased dP/dt in the absence of any structural modifications in the arterial wall. Although NO production and ET-1 levels were not altered by ETS, there was increased biological inactivation of NO via peroxynitrite production (as indicated by increased plasma nitrotyrosine levels). Thus, vascular stiffness and failure of blood pressure to dip precede structural changes in rats exposed to ETS for 28 days. Exposure to ETS also caused increased number of lung neutrophils as well as increased CYP1A1 activity in lung microsomes.<p> Since ETS-induced increases in arterial stiffness occurred as early as day 7, radiotelemetry-implanted rats were exposed daily to intranasal BaP for 7 days. Similar to ETS, BaP exposure altered circadian blood pressure patterns and reduced blood pressure dipping during sleep. Thus, in support of part of our hypothesis, the PAH component of cigarette smoke may be responsible for the ETS-induced increase in blood pressure and the loss of dipping pattern during sleep. Increased neutrophil recruitment was observed in the lungs of both ETS- and BaP-exposed rats, suggesting that lung inflammatory reactions may be involved in the disruption of circadian blood pressure rhythms. Unlike ETS however, BaP exposure did not significantly alter pulse wave dP/dt, endothelial function, or lung CYP1A1 activity. Thus, contrary to our hypothesis, the reduction in NO bioactivity and increased arterial stiffness caused by ETS cannot be explained by BaP at the dose and length of the exposure in the current study. Production of reactive metabolites in the lung following ETS exposure may be responsible, at least in part, for the increases in oxidative stress in the vasculature, leading to reduced NO bioactivity and increased arterial stiffness. Oxidative stress caused by BaP exposure may have been insufficient to reduce NO bioactivity in the peripheral vasculature. Therefore arterial stiffness was not increased and factors other than NO may be responsible for the increase in blood pressure observed with ETS and BaP exposure.

An age-related decline in cerebral blood flow (CBF) is widely acknowledged. However, uncertainty exists as to whether this reduction is the result of a reduced metabolic demand (cerebral atrophy) or an impaired delivery system (cerebrovascular disease). The purpose of these experiments was to examine the relationship of CBF and dynamic cerebrovascular regulation with changes in common carotid intima-media thickness (cIMT), brachial-ankle pulse wave velocity (baPWV) and common carotid distensibility. Additionally, we took an exploratory view into the effect of vascular aging and CBF reduction on brain function, as expressed through the performance of motor and cognitive tasks. An important finding in elderly participants was that seated anterior CBF declined as a function of arterial stiffness, independently of age. Linear regression analysis developed a model that predicts CBF drops 22 ml/min (95% confidence interval (CI): 6, 38) for each 100 cm/s increase in baPWV and 8 ml/min (95% CI: 1, 15) for each additional year in age. The effect of baPWV appears to be mediated through an increase in cerebrovascular resistance (r2 = 0.84, p < 0.0001). Additionally, CBF showed postural dependency and the volume of the drop in CBF between supine and seated positions was greatest in elderly participants (YOUNG: 65 ± 81 ml/min; ELDERLY: 155 ± 119 ml/min; p = 0.001). Despite this negative impact of vascular aging on steady state flow, dynamic regulation does not appear to be affected. Cerebrovascular responses to an acute drop in blood pressure or to activation of the motor cortex were not attenuated in the elderly participants. Finally, seated CBF had modest directionally relevant relationships with perceptuo-motor and complex sequencing processes; while cIMT appeared to influence performance on initiation and inhibition tasks.

Electrostatically actuated parallel-plate MEMS tunable capacitors are desired elements for different applications including sensing, actuating and communications and RF (radio frequency) engineering for their superior characteristics such as quick response, high Q-factor and small size. However, due to the nature of their coupled electrostatic-structural physics, they suffer from low tuning range of 50% and have nonlinear capacitance-voltage (C-V) responses which are very sensitive to the voltage change near pull-in voltage. Numerous studies in the literature introduce new designs with high tunability ranging from 100% to over 1500%, but improvement of the nonlinearity and high sensitivity of the capacitor response have not received enough attention. In this thesis, novel highly tunable capacitors with high linearity are proposed to reduce sensitivity to the voltage changes near pull-in. The characteristic equations of a perfectly linear capacitor are first derived for two- and three-plate capacitors to obtain insight for developing linear capacitance-voltage responses. The devices proposed in this research may be classified into three categories: designs with nonlinear structural rigidities, geometric modifications and flexible moving electrodes. The concept of nonlinear supporting beams is exploited to develop parallel-plate capacitors with partially linear C-V curves. Novel electrodes with triangular, trapezoidal, butterfly, zigzag and fishbone shapes and structural/geometric nonlinearities are used to increase the linearity and tuning ratio of the response. To investigate the capacitors' behavior, an analytical approximate model is developed which can drastically decrease the computation time. The model is ideal for early design and optimization stages. Using this model, design variables are optimized for maximum linearity of the C-V responses. The results of the proposed modeling approach are verified by ANSYS FEM simulations and/or experimental data. When the fabrication process has dimensional limitations, design modifications and geometric enhancements are implemented to improve the linearity of the C-V response. The design techniques proposed in this thesis can provide tunabilities ranging from 80% to over 350% with highly linear regions in resulting C-V curves. Due to the low sensitivity of the capacitance to voltage changes in new designs, the entire tuning range is usable. Furthermore, the effect of fabrication uncertainties on parallel-plate capacitors performance is studied and a sensitivity analysis is performed to find the design variables with maximum impact on the C-V curves. An optimization method is then introduced to immunize the design against fabrication uncertainties and to maximize the production yield for MEMS tunable capacitors. The method approximates the feasible region and the probability distribution functions of the design variables to directly maximize the yield. Numerical examples with two different sets of design variables demonstrate significant increase in the yield. The presented optimization method can be advantageously utilized in design stage to improve the yield without increasing the fabrication cost or complexity.

Background: Prolonged sitting in an automobile seat may alter the passive tissue stiffness of the lumbar spine differentially in males and females. Gender specific ergonomic interventions may be indicated for the automobile seat design. Purpose: To compare time-varying passive lumbar spine stiffness in response to a two hour simulated driving trial with time-varying lumbar spine and pelvic postures during sitting in an automobile seat. A secondary purpose was to investigate gender differences in lumbar spine stiffness, seat/occupant pressure profile, discomfort rating and posture. Methods: Twenty (10 males, 10 females) subjects with no recent history of back pain were recruited from a university population. Participants completed a simulated driving task for two hours. Passive lumbar range of motion was measured on a customized frictionless jig before, halfway through and at the end of the two-hour driving trial. Changes in the passive moment-angle curves were quantified using the transition zone slopes, breakpoints and maximum lumbar flexion angles. Lumbar spine and pelvic postures were monitored continuously during the simulated driving trial with average and maximum lumbar flexion angles as well as pelvic tilt angles being calculated. Results: Both men and women initially demonstrated an increase in transitional zone stiffness after 1 hour of sitting. After 2 hours of sitting, transitional zone stiffness was found to increase in males and decrease in females. During sitting, women were found to sit with significantly greater lumbar flexion than males and to significantly change the amount of lumbar flexion over the 2 hour period of simulated driving. Conclusions: Postural differences during simulated driving were demonstrated between genders in this study. In order to prevent injury to the passive elements of the spine during prolonged driving, gender specific ergonomic interventions, such as improved lumbar support, are indicated for the automobile seat.