Thesis (Ph.D.)--University of Delaware, 2007. / Principal faculty advisors: John F. Rabolt and D. Bruce Chase, Dept. of Materials Science & Engineering. Includes bibliographical references.

Resumo: Objetivos: avaliar as alterações morfológicas das fibras musculares estriadas tipos I e II da uretra de ratas prenhes diabéticas submetidas à cesárea. Métodos: Foram avaliadas 20 ratas Wistar distribuídas em quatro grupos: virgem, prenhe, diabético virgem e prenhe diabético. Os três primeiros grupos foram estudados para servir como controle do grupo principal, o prenhe diabético. O diabete foi induzido com streptozotocin na dose de 40mg/kg de peso corpóreo. O critério de inclusão foi uma glicemia acima de 200mg/dL. No final do experimento, as ratas foram anestesiadas e eutanasiadas para realização da laparotomia exploratória. A vagina e a uretra foram retiradas em monobloco, congeladas em nitrogênio líquido e mantidas a -80°C. O bloco foi submetido a cortes em criostato (6 μm de espessura). As lâminas foram coradas por H&E e utilizados anticorpos anti-miosina lenta e rápida para tipagem das fibras. Foi realizada análise morfológica e semi-quantitativa dos quatro grupos. Resultados: O músculo estriado uretral do grupo prenhe diabético apresentou: adelgaçamento, atrofia, desorganização e rompimento associado à perda de localização anatômica normal das fibras rápidas e lentas e diminuição na proporção de fibras rápidas. Conclusões: Este estudo sugere que o binômio diabete e prenhez danificou o músculo estriado uretral e alterou a composição e a distribuição das fibras tipo I e II . / Abstract: Urinary incontinence (UI) in women is defined as any involuntary urine loss. It is a frequent condition of high economic cost to the government that also results in women's physical, psychological and social damage and impaired quality of life. Various risk factors are involved in UI development; however, association with Diabetes mellitus (DM) is of great interest at present. DM affects multiple organ systems, including the urinary system in approximately 52% of diabetic patients and in those showing only hyperglycemia; however, the association between gestational DM and UI has not been fully explained. Health care professionals must be attentive to this new parameter and attempt to analyze it in more detail so that prophylactic and therapeutic measures can be established. It is necessary to delineate the chronology of the relationship between gestational Diabetes mellitus and vesical complications, the relationship between controlled diabetes and the incidence of incontinence as well as effective treatment modalities for diabetic patients with symptoms in the lower urinary tract. / Orientador: Marilza Vieira Cunha Rudge / Coorientador: Angélica Mércia Pascon Barbosa / Coorientador: Selma Maria Michelin Matheus / Banca: Débora Cristina Damasceno / Banca: Jorge Milhen Haddad / Mestre

Made available in DSpace on 2014-06-11T19:29:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-25Bitstream added on 2014-06-13T18:39:54Z : No. of bitstreams: 1 marini_g_me_botfm.pdf: 541869 bytes, checksum: 5d00927490e16293300df917e946209a (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Objetivos: avaliar as alterações morfológicas das fibras musculares estriadas tipos I e II da uretra de ratas prenhes diabéticas submetidas à cesárea. Métodos: Foram avaliadas 20 ratas Wistar distribuídas em quatro grupos: virgem, prenhe, diabético virgem e prenhe diabético. Os três primeiros grupos foram estudados para servir como controle do grupo principal, o prenhe diabético. O diabete foi induzido com streptozotocin na dose de 40mg/kg de peso corpóreo. O critério de inclusão foi uma glicemia acima de 200mg/dL. No final do experimento, as ratas foram anestesiadas e eutanasiadas para realização da laparotomia exploratória. A vagina e a uretra foram retiradas em monobloco, congeladas em nitrogênio líquido e mantidas a -80°C. O bloco foi submetido a cortes em criostato (6 μm de espessura). As lâminas foram coradas por H&E e utilizados anticorpos anti-miosina lenta e rápida para tipagem das fibras. Foi realizada análise morfológica e semi-quantitativa dos quatro grupos. Resultados: O músculo estriado uretral do grupo prenhe diabético apresentou: adelgaçamento, atrofia, desorganização e rompimento associado à perda de localização anatômica normal das fibras rápidas e lentas e diminuição na proporção de fibras rápidas. Conclusões: Este estudo sugere que o binômio diabete e prenhez danificou o músculo estriado uretral e alterou a composição e a distribuição das fibras tipo I e II . / Urinary incontinence (UI) in women is defined as any involuntary urine loss. It is a frequent condition of high economic cost to the government that also results in women’s physical, psychological and social damage and impaired quality of life. Various risk factors are involved in UI development; however, association with Diabetes mellitus (DM) is of great interest at present. DM affects multiple organ systems, including the urinary system in approximately 52% of diabetic patients and in those showing only hyperglycemia; however, the association between gestational DM and UI has not been fully explained. Health care professionals must be attentive to this new parameter and attempt to analyze it in more detail so that prophylactic and therapeutic measures can be established. It is necessary to delineate the chronology of the relationship between gestational Diabetes mellitus and vesical complications, the relationship between controlled diabetes and the incidence of incontinence as well as effective treatment modalities for diabetic patients with symptoms in the lower urinary tract.

No description available.

The home is a material place of routine and isolation. Cyberspace, on the other hand, is associated with the lightness of disembodiment and engagement with others in virtual worlds. I am interested in the home as a locale of cyberspace in regard to the relationship between attaching and detaching, territorializing and de-territorializing, the smooth and the striated. My experimentation is about frozen moments in day-to-day situations. Through experiments with light, materials and installations, I intend to draw out a tactile perspective on cyberspace and domesticity. In terms of materials, I am particularly interested in the residues in everyday life. Light and materials are considered to be tactile as well as visual. Performativity, Heuristics and Active Documentation are my main methodological approaches. My work does not seek to fix a solution, but open up an area of ongoing discovery. The physical makings are the ignition for later developments. Once the installation has been set up, the performativity is transferred to the audience. The surrounding space becomes activated because of the energy released by the audience's engagement. Heuristic use of intuition and informal experience was applied in my working process to discover imperceptible traits of materials and daily situations. Active Documentation helps me to re-consider, re-negotiate, reflect and renew my work throughout the project. In this way, hidden codes can be brought out to the surface.

The home is a material place of routine and isolation. Cyberspace, on the other hand, is associated with the lightness of disembodiment and engagement with others in virtual worlds. I am interested in the home as a locale of cyberspace in regard to the relationship between attaching and detaching, territorializing and de-territorializing, the smooth and the striated. My experimentation is about frozen moments in day-to-day situations. Through experiments with light, materials and installations, I intend to draw out a tactile perspective on cyberspace and domesticity. In terms of materials, I am particularly interested in the residues in everyday life. Light and materials are considered to be tactile as well as visual. Performativity, Heuristics and Active Documentation are my main methodological approaches. My work does not seek to fix a solution, but open up an area of ongoing discovery. The physical makings are the ignition for later developments. Once the installation has been set up, the performativity is transferred to the audience. The surrounding space becomes activated because of the energy released by the audience's engagement. Heuristic use of intuition and informal experience was applied in my working process to discover imperceptible traits of materials and daily situations. Active Documentation helps me to re-consider, re-negotiate, reflect and renew my work throughout the project. In this way, hidden codes can be brought out to the surface.

Thesis (Ph. D.)--University of Oregon, 2008. / Typescript. Includes vita and abstract. Includes bibliographical references (leaves 151-168). Also available online in Scholars' Bank; and in ProQuest, free to University of Oregon users.

Thesis (M.S.)--School of Bioengineering, Georgia Institute of Technology, 2005. Directed by Thomas Burkholder. / Thomas Burkholder, Committee Chair ; Cheng Zhu, Committee Member ; Grace Pavlath, Committee Member. Includes bibliographical references.

No description available.

A Síndrome da fibromialgia é caracterizada pela presença de dor muscular crônica e difusa em pelo menos onze pontos do corpo humano denominados de tender points, rigidez matinal, fadiga, distúrbios do sono, sintomatologia dolorosa extensa na face, que se manifesta principalmente nos músculos mastigatórios, articulação temporomandibular e na região auricular. O objetivo desta pesquisa foi analisar os músculos mastigatórios (masseter e temporal) e cervicais (esternocleidomastoideo e trapézio) em mulheres com diagnóstico de síndrome da fibromialgia. Participaram dessa pesquisa sessenta e oito mulheres na faixa etária entre 40 a 60 anos de idade, distribuídas em dois grupos distintos: GF: síndrome de fibromialgia (n=34) e GC: controle saudável (n=34). O eletromiógrafo Myosystem-Br1 foi utilizado para analisar a atividade EMG. As imagens das espessuras dos músculos mastigatórios e cervicais foram adquiridas pelo ultrassom Sonosite Titan. A força de mordida molar máxima foi obtida por meio de dinamômetro digital Kratos. Os dados da atividade EMG, espessura muscular e força de mordida molar foram tabulados, normalizados e submetidos à análise estatística (SPSS 21.0). Houve diferença estatística significante (p <= 0,05) entre GF e GC em todas as condições posturais mandibulares, na mastigação (habitual e não habitual), espessura muscular e força de mordida molar, com dados médios menores para GF. Baseados nos resultados desta pesquisa, os autores concluíram que mulheres com síndrome da fibromialgia apresentaram alterações no sistema estomatognático / Fibromyalgia syndrome is characterized by chronic and diffuse muscle pain in at least eleven points of the human body (tender points), morning stiffness, fatigue, sleep disturbances, extensive pain symptoms in the face, which is mainly manifested in the masticatory muscles, temporomandibular joint and ear region. The aim of this study was to analyze the masticatory (masseter and temporal) and cervical (sternocleidomastoid and trapezius) muscles in women with diagnosis of fibromyalgia syndrome. Sixty-eight women aged between 40 and 60 years participated in this research. They were divided into two distinct groups: FG: fibromyalgia syndrome (n = 34) and CG: healthy control (n = 34). The Myosystem-Br1 electromyography was used to analyze the EMG activity. The thicknesses of the masticatory and neck muscles were acquired by ultrasound Sonosite Titan. The maximum molar bite force was obtained using a digital force gauge Kratos. The data of EMG activity, muscles thickness and maximal molar bite force were tabulated, standardized and subjected to statistical analysis (SPSS 21.0). There were statistically significant differences (p<= 0.05) between FG and CG at all mandibular postural conditions, chewing, muscle thickness and molar bite force, with lower average data for FG. Based on the results of this research, the authors concluded that women with fibromyalgia syndrome have alterations in the stomatognathic system