The aim of the study was to analyse the survival strategies of the poor households in Boitumelo township. The research methodology used herein was two fold: Firstly, a literature research based on economic journals, previous research projects, books and internet was done in order to develop a better understanding of poverty. Secondly, an empirical research survey using questionnaires was undertaken. Over the years there have been competing theories which provide an understanding of poverty. Each approach has its strengths and weaknesses. Poverty captures a wide range of meanings, depending on who is defining it. Although various technical solutions have been suggested for differentiating the poor and non-poor using the monetary approach, there is no theory of poverty that clearly differentiate the poor from the non-poor. The survey results showed that 41% of all households in Boitumelo are poor and on average have an income shortage of 63% to the poverty line. Poverty within the area has a gender bias as 76% of the poor are females. The large number of households below the poverty line provided ample opportunity for further analysis to find out about the activities that they use to sustain themselves. Being unemployed in government or manufacturing industries, the urban poor are compelled to create some sort of jobs for themselves. Street vending, odd jobs, gambling, seeking credit on exploitative terms, income from state welfare, begging for survival are just a few of the activities urban poor adopt to survive / Thesis (MCom (Economics))--North-West University, Vaal Triangle Campus, 2013

Time-to-event data is used in this thesis to analyze private cars’ longevity in Sweden. Thedataset is provided by Trafikanalys and contains all registered, deregistered or temporary deregisteredcars in Sweden during the time period 2000 - 2012.A Cox proportional hazards model is fitted, including variables such as car manufacturer andcar body. The results show that directly imported cars have a much shorter median survivalcompared to non-imported cars. The convertible cars have the longest median survival amongthe five different car bodies. Sedan and station wagon body types have the shortest mediansurvival. Volvo and Mercedes have the longest survival while Renault, Ford and Opel have theshortest survival. The model fits the data reasonably well, and the assumption of proportionalhazards holds for most of the variables.

Even a well planned marketing strategy may fail if a country or region goes through a rapid business decline. As consumers' income drops, they must shift their spending patterns. They may have to simply do without some products. By carefully studying the environment, marketers can adapt their strategies to meet market place challenges and opportunities. This generally means adapting the marketing mix and/or changing the target markets. However, the response of marketing managers to recession depends on how they perceive its meaning and impact on their businesses. The purpose of the study was identified to be the determination of managements' perception of and response to economic recession by measuring (1) the meaning of the economic recession to marketing managers; (2) the impact of this recession on marketing decisions; and (3) the resultant adjustments in marketing strategy and action. Primary and secondary data was gathered through literature review and empirical research, respectfully. Data collection consisted of a structured questionnaire to serve as guideline for the follow-up interviews. A total of ten marketing managers participated in the qualitative interviews. These managers were selected by means of a non-probability sample. The recent recession has seen South Africa's real GDP growth slowing to 3% with unemployment rate increasing slightly to 23.6%, manufacturing production falling by contraction of 17.2% whilst the year-on-year CPI inflation rate was 8.1% in January 2009. These foregoing show how severe the recession has been. All interviewed respondents reported price competition to have been fierce during the recent economic recession. In their quest to minimise the effects of the economic downturn, companies adjusted their sales volumes and improvised their marketing spent by using more of company websites and e-mail marketing to keep customer informed of the product or service offerings available. / Thesis (M.B.A.)--North-West University, Potchefstroom Campus, 2011.

Diffuse large B-cell lymphoma (DLBCL), which is the most common type of lymphoma, is characterised by its aggressiveness and poor outcome without adequate treatment and also for its biological and clinical heterogeneity. It is therefore highly desirable to gain a more profound understanding of the underlying biology of the disease, as well as predictive factors for the guidance of treatment. The studies presented here attempt to gain an overall grasp on DLBCL, from the epidemiological level down to the genomic level. The tumour microenvironment consists of both tumour cells and normal infiltrating cells in a delicate interplay. By assessing the number of infiltrating mast cells (MCs) in the microenvironment, a correlation between low numbers of MCs and poorer prognosis of DLBCL was found. However, malignant cells are not only affected by environmental conditions but also by intrinsic factors, such as small non-coding microRNAs. A low expression level of microRNA-129 was found to correlate with poor survival of DLBCL and the finding remained significant even for rituximab-treated patients. An even smaller intracellular genomic unit is one single nucleotide. The single nucleotide polymorphism 309 (SNP309) is a T to G change in the promotor region of MDM2, a regulatory protein in the p53 pathway, which results in increased transcription of MDM2 and thus decreased levels of p53. It was found that homozygous T allele patients had longer overall survival, as well as disease-specific survival and disease-free survival. However, treatment with rituximab eliminated the predictive value of the SNP309 polymorphism. In the last project presented in this thesis we used epidemiological methods to analyse all DLBCL cases diagnosed 2000-2013 in Sweden. Here it was possible to categorically show that higher age is an adverse prognostic factor, and most importantly, this starts from a young age. In conclusion, within this thesis I have applied different laboratory and analysis techniques to examine DLBCL biology in relation to the clinic. I have identified potential new prognostic markers, contributed to an enhanced understanding of DLBCL biology and described epidemiological data from one of the largest DLBCL cohorts ever presented. All of these aspects provide important information for a deeper understanding of the disease DLBCL.

Even a well planned marketing strategy may fail if a country or region goes through a rapid business decline. As consumers' income drops, they must shift their spending patterns. They may have to simply do without some products. By carefully studying the environment, marketers can adapt their strategies to meet market place challenges and opportunities. This generally means adapting the marketing mix and/or changing the target markets. However, the response of marketing managers to recession depends on how they perceive its meaning and impact on their businesses. The purpose of the study was identified to be the determination of managements' perception of and response to economic recession by measuring (1) the meaning of the economic recession to marketing managers; (2) the impact of this recession on marketing decisions; and (3) the resultant adjustments in marketing strategy and action. Primary and secondary data was gathered through literature review and empirical research, respectfully. Data collection consisted of a structured questionnaire to serve as guideline for the follow-up interviews. A total of ten marketing managers participated in the qualitative interviews. These managers were selected by means of a non-probability sample. The recent recession has seen South Africa's real GDP growth slowing to 3% with unemployment rate increasing slightly to 23.6%, manufacturing production falling by contraction of 17.2% whilst the year-on-year CPI inflation rate was 8.1% in January 2009. These foregoing show how severe the recession has been. All interviewed respondents reported price competition to have been fierce during the recent economic recession. In their quest to minimise the effects of the economic downturn, companies adjusted their sales volumes and improvised their marketing spent by using more of company websites and e-mail marketing to keep customer informed of the product or service offerings available. / Thesis (M.B.A.)--North-West University, Potchefstroom Campus, 2011.

This paper examines the concept of uploading one’s consciousness on to a computer, and its role in personal identity. I first examine the technology behind uploading, and the likely timeline for that technology to become widespread. Then taking uploading as a given, I examine our intuitions about how we will interact with these uploads on a daily basis. Then, I argue that Derek Parfit’s account of survival and identity is the one best suited for a post-upload world. After explaining the benefits of Parfit’s view in this world, I defend Parfit against criticisms by Eric Olson, and Susan Schneider. Finally, I show why animalism and four-dimensionalism are not as strong of accounts of personal identity as Parfit’s view, in a world where uploading is a reality.

Evidence suggests that the variability in recruitment of adult Pacific salmon is related to smolt survival during the first ocean year. Specifically, the first few weeks and first marine winter may be two critical periods of high mortality during early marine life. Mortality during early marine residency has been attributed to predation and size-dependent factors while high mortality during the first winter may be due to energy deficits and failure to reach a certain size by the end of the growing season. My study assessed factors influencing overwinter mortality and early marine growth in juvenile Chinook salmon (Oncorhynchus tshawytscha) from Marble River, Quatsino Sound, British Columbia. Juvenile salmon were collected during November 2005 and 2006 (fall) and March 2006 and 2007(winter). Mortality rates over the first winter derived from catch per unit effort across seasons ranged between 80-90% in all years. These are the first estimations of overwinter mortality in juvenile Pacific salmon. Fish size distributions showed no evidence of size-selective overwinter mortality between fall and winter fish in either 2005-2006 or 2006-2007. Otolith microstructure analyses showed no significant difference in circulus increment widths during the first four weeks after marine entry. Similarities in increment width indicated that early marine growth did not differ between fall and winter fish during early marine residency in 2006. These observations show that the high overwinter mortality rates of juvenile Chinook salmon in Quatsino Sound are not size-dependent. Total plankton biomass was significantly lower in the winter season but size distribution, gut fullness and energy density data did not show evidence of starvation. No correlation was found between early marine growth, size, energy accumulation and high mortality in Marble River juvenile Chinook salmon during their first ocean winter in Quatsino Sound. Possible factors influencing these high mortality rates may include non size-selective predation, disease, local environmental influences or an as yet unknown source. Future work should continue to focus on understanding the relationship between early marine survival and adult recruitment. The expansion of growth comparisons geographically and chronologically while determining the effects of predatory mortality on juvenile Chinook salmon along the north Pacific continental shelf and beyond are imperative to fully understanding this complex marine life stage. / Graduate

Kevlar materials offer excellent tensile and thermal properties but can rapidly degrade under exposure to hot and humid environmental conditions. Currently Kevlar fiber's survival probability comes from a single filament test. Unfortunately, the single filament test is a tedious process and prone to operator bias, leading to inaccurate survival function that does not represent the actual survival function. This research aims to validate the fiber bundle test to replace the single filament test in extracting Kevlar’s survival function. Another important aspect is determining the factors that cause the fiber to lose its properties. This research also aims to determine the factors that degrade Kevlar fibers and those factors’ combined effects on degrading the KM2 fiber. This information is essential for safety factor design when exposure to these environmental factors would cause the Kevlar KM2 to fail prematurely. Results from experimental data and analysis indicate that the fiber bundle test is a good replacement for single filament tests and estimation techniques can determine the bundle Weibull parameters. Furthermore, the survival function for treated fibers is better if the bundle is lubricated. The accelerated aging experiments show that accelerated aging is possible with combined temperature and moisture. Kevlar KM2 bundle conditioned at 270 °C and 150 g water for 3 hours lost over 95% of its breaking strength. This is comparable to Kevlar bundles treated for over 500 hours in 250 °C or treated for over 100 days in 100% relative humidity environment at 80 °C found in literature.

This thesis addresses the challenge of prognosis, in terms of survival prediction, for patients with Glioblastoma Multiforme brain tumors. Glioblastoma is the most malignant brain tumor, which has a median survival time of no more than a year. Accurate assessment of prognostic factors is critical in deciding amongst different treatment options and in designing stratified clinical trials. This thesis is motivated by two observations. Firstly, clinicians often refer to properties of glioblastoma tumors based on magnetic resonance images when assessing prognosis. However, clinical data, along with histological and most recently, molecular and gene expression data, have been more widely and systematically studied and used in prognosis assessment than image based information. Secondly, patient survival times are often used along with clinical data to conduct population studies on brain tumor patients. Recursive Partitioning Analysis is typically used in these population studies. However, researchers validate and assess the predictive power of these models by measuring the statistical association between survival groups and survival times. In this thesis, we propose a learning approach that uses historical training data to produce a system that predicts patient survival. We introduce a classification model for predicting patient survival class, which uses texture based features extracted from magnetic resonance images as well as other patient properties. Our prognosis approach is novel as it is the first to use image-extracted textural characteristics of glioblastoma scans, in a classification model whose accuracy can be reliably validated by cross validation. We show that our approach is a promising new direction for prognosis in brain tumor patients.

MPhilPH / Female tubal sterilisation, often referred to as "tubal ligation" but more often performed these days using laparoscopically-applied metal clips, remains a popular form of contraception in women who have completed their families. A review of the literature on the incidence of failure of tubal sterilisation found many reports of case-series and small clinic-based studies, but only a few larger studies with good epidemiological designs, most recently the US CREST study conducted during the 1980s and early 1990s. The CREST study reported a conditional (life-table) cumulative incidence of failure of 0.55, 0.84, 1.18 and 1.85 per 100 women at 1, 2, 4 and 10 years of follow-up respectively. The study described here estimated a lower bound for the incidence of tubal sterilisation failure in NSW by probabilistically linking routinely-collected hospital admission records for women undergoing sterilisation surgery to hospital admission records for the same women which were indicative of subsequent conception or which represented censoring events such as hysterectomy or death in hospital. Data for the period July 1992 to June 2000 were used. Kaplan-Meier and proportional-hazards survival analyses were performed on the resulting linked data set. The conditional cumulative incidence per 100 women at 1, 2 4 and 8 years of follow-up was estimated to be 0.74 (95% CI 0.68-0.81), 1.05 (0.97-1.13), 1.33 (1.23-1.42) and 1.51 (1.39-1.62) respectively. Forty percent of failures ended in abortion and 14% presented as ectopic pregnancies. Age, private health insurance status and sterilisation in a smaller hospital were all found to be associated with lower rates of failure. Strong evidence of time-limited excess numbers of failures in women undergoing surgery in particular hospitals was also found. The study demonstrates the feasibility of using linked, routinely-collected health data to evaluate relatively rare, long-term outcomes such as sterilisation failure on a population-wide basis.