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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
51

The interactions between BK virus and host cell receptors.

Dugan, Aisling Siobhan. January 2008 (has links)
Thesis (Ph.D.)--Brown University, 2008. / Vita. Advisor: Walter J. Atwood. Includes bibliographical references (leaves 172-175).
52

Allocating scarce resources an ethical case study of organ transplantation /

Fisher, Karen Joan, January 1997 (has links)
Thesis (M.A.)--Denver Seminary, 1997. / Includes bibliographical references (leaves [115]-122).
53

[The] ethical evaluation of brain dead persons and organ transplantation in contemporary Muslim ethics

Moalimishak, Mohamed Rashad. January 2008 (has links)
This dissertation is primarily about the ethical evaluation ofbrain death, brain-dead persons and organ transplantation in contemporary Muslim ethics. / Cette tQese est premierement au sujet de l'évaluation éthique de la mort cérébrale et les personnes dans un coma dépassé aux éthiques Musulmanes contemporaines.
54

The child as tissue and organ donor

Crouch, Robert Alan January 1996 (has links)
This thesis attempts to answer the following question: Is it ever morally permissible to use a minor child as a tissue or organ donor for the benefit of a family member? Those sceptical of using minors as tissue or organ donors for the benefit of a sick family member will highlight two points: the donor will be subject to risks that are not counterbalanced by possible medical benefits, and the minor cannot consent to the procedure herself. / This thesis will present a review of the medical risks associated with bone marrow and kidney donations, as well as a review of the common law dealing with donations by minors and incompetent persons. The final chapter then makes a case for the permissibility of minor donation based on the interests of the family.
55

Characterization and prevention of the “small-for-size” syndrome in a porcine model of hepatic transplant

Hessheimer, Amelia Judith 13 April 2011 (has links)
The hypothesis of this doctoral thesis is two-fold: 1. Excessive portal vein flow is present immediately after portal reperfusion in the recipient and is the instigating factors in a series of events that ultimately lead to the development of “small-for-size” syndrome (SFSS). 2. A calibrated portocaval shunt prevents postreperfusion portal hyperperfusion and, thereby, the development of SFSS in partial liver grafts. The objectives of this doctoral thesis are as follows: 1. To produce a porcine model of acute SFS injury that does not use venovenous bypass, in order to study the presentation of SFSS and characterize the cellular lesion in relation to altered hepatic hemodynamics. 2. To study the effects of modifying portal vein flow through the creation of portocaval shunts of different sizes, each calibrated to achieve a distinct decrease in the amount of flow ultimately reaching the SFS liver graft. 3. To determine the optimal decrease in the amount of portal vein flow that is capable of preventing the deleterious consequences of portal hyperperfusion and improving postoperative graft function and survival in SFS liver grafts. / El trasplante hepático es el único tratamiento para pacientes que presentan enfermedad hepática en estado terminal pero la demanda de injertos hepáticos para trasplante excede enormemente el número de órganos disponibles. Debido a que un hígado sano posee una importante reserva funcional y capacidad regenerativa, el uso de injertos parciales representa una alternativa al trasplante con injertos de hígado completo. Sin embargo, el trasplante de injertos parciales requiere un estudio preoperatorio extenso para asegurar la obtención de un injerto adecuado funcionalmente para el receptor, así como una adecuada masa hepática remanente para el donante, y de este modo evitar el desarrollo del síndrome de “small-for-size” (SFS). Dicho síndrome se diagnostica clínicamente cuando aparece colestasis prolongada, coagulopatía, encefalopatía, ascitis intratable, hemorragia gastrointestinal y/o fallo renal en un paciente con una masa hepática <0.8% del peso del receptor o <30-40% del volumen hepático estándar, una vez se han excluido otras causas. Cuando el síndrome SFS aparece, provoca el fracaso del injerto hasta en el 50% de los receptores. La patogénesis del síndrome SFS es multifactorial y se ha asociado no sólo al hecho de trasplantar una masa hepática reducida, también a la presencia de un excesivo flujo portal, a una dificultad en el drenaje venoso a través de las venas hepáticas, a las condiciones físicas y metabólicas del receptor, a la esteatosis hepática y a una funcionalidad insuficiente del propio injerto en general. El flujo portal en particular es considerado como un factor esencial involucrado en la aparición de la disfunción y el fallo de un injerto hepático parcial. Aparte de una cuidadosa evaluación preoperatoria para evitar el trasplante de un injerto pequeño, se han utilizado varias estrategias adicionales en el ámbito clínico para evitar la aparición del síndrome SFS. La mayoría de dichas estrategias son quirúrgicas y consisten en procedimientos para favorecer el flujo de salida del injerto mediante la reconstrucción de las venas tributarias de la vena hepática media y/o la realización de venoplastias en las venas hepáticas, o en la reducción del flujo de entrada portal al injerto a través de la ligadura de la arteria esplénica, la realización de una esplenectomía y/o la creación de un shunt portocaval parcial. Las estrategias farmacológicas para la prevención de síndrome SFS han sido extensamente aplicadas en el contexto experimental, pero la experiencia clínica es muy limitada. El estudio del síndrome SFS en humanos es complicado ya que su aparición no es frecuente y cuando se sospecha se utilizan todos los mecanismos para intentar evitarlo. Por tanto, para obtener un mejor conocimiento de la patogénesis del síndrome de SFS en el contexto del trasplante hepático parcial, es importante desarrollar un modelo animal apropiado. Para conseguir este objetivo, varios grupos de investigadores han establecido diferentes modelos animales; algunos con animales pequeños como rata y ratón. Sin embargo, los modelos con animales grandes presentan características anatómicas y de tamaño que son directamente aplicables al ámbito clínico.
56

Photoacoustic discrimination of viable and thermally coagulated blood for burn injury imaging

Talbert, Robert John, January 2007 (has links)
Thesis (M.S.)--University of Missouri-Columbia, 2007. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on January 11, 2008) Includes bibliographical references.
57

Microtransplantation of nigral dopamine neurons in a rat model of Parkinson's disease studies on functional recovery and structural repair in adult and neonatal rats with lesions of the mesotelencephalic dopamine system /

Nikkhah, Guido. January 1994 (has links)
Thesis (doctoral)--Lund University, 1994. / Added t.p. with thesis statement inserted.
58

Stabilization of irradiated allografts via crosslinking and free radical scavenging

Seto, Aaron U. January 2007 (has links)
Thesis (M.S.)--Rutgers University, 2007. / "Graduate Program in Biomedical Engineering." Includes bibliographical references (p. 80-85).
59

Organ donation and transplantation /

Pummer-Verté, Lila. January 1995 (has links)
Thesis (M.F.A.)--Rochester Institute of Technology, 1995. / Typescript. Includes bibliographical references (leaves 55-56).
60

Black critical care nurses' perceptions of organ donation and organ transplantation

Shubane, Nancy. January 2009 (has links)
Thesis (MCur (Nursing Science))--University of Pretoria, 2009. / Summary in English. Includes bibliographical references.

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