Histories o f childhood and youth have generally focused upon social policy toward young people. This dissertation chronicles the actual experiences of youth growing up in and around Williams Lake in the Cariboo-Chilcotin region of British Columbia, a "western" community surrounded by open spaces, ranches, and Aboriginal reservations. Williams Lake underwent economic, demographic, spatial as well as social transformation in the first three decades following the Second World War. Forty-three oral interviews with two sets o f subjects who were adolescents in the study area furnished the bulk of the primary evidence. Most of the first "generation" were bom in the Great Depression and were teens sometime between 1945 and 1955. The second generation are "baby-boomers" bom between 1947 and 1962 who were teens between 1965 and 1975. This joint narrative details select aspects o f their lives at school, at paid and unpaid labour, with friends, and at leisure. It suggests changes and continuities in the experience of local youth between 1945 and 1975. First generation non-Aboriginal subjects grew up with a somewhat coherent peer group albeit with relatively little physical and social contact with Aboriginal youth. Gendered domestic labour around home and property honed work skills and dispositions from an early age. The emergence of local sawmills greatly expanded work options for males but not females. Males also enjoyed comparatively more spatial and temporal freedom throughout their youth. Second generation subjects grew up in a context of greater urbanization and access to mass culture. The merger of regional youth in the high school along with natural population growth, demographic change including the enrollment of first Aboriginal and then Indo-Canadian youth encouraged factions as well as cultural gulfs among youth in the school and community. Their leisure was comparatively less divided, at least on the basis of gender, as many non-Aboriginal parents eased traditional restrictions upon daughters. With notable exceptions this generation contributed less labour to their household and directed part- and full-time earnings into satisfying their own personal interests. The author suggests the pattern of youths' recreational use of hinterlands during the period reflects common practice in many Canadian communities located in similar rural and isolated settings. He illustrates how factors such as family affluence and circumstances, gender, "race" and ethnicity continued to mediate the experience of growing up in this post-war period. He concludes many more local accounts of the experiences of youth are needed before any attempt is made at an inclusive national historical synthesis of growing up in Canada after the Second World War. / Education, Faculty of / Educational Studies (EDST), Department of / Graduate

Through the analysis of selected works for flute by Argentine composers Amancio Alcorta (1805-1862), Alberto Williams (1862-1952) and Ángel Lasala (1914- 2000), the progressive evolution of a Nationalistic style becomes evident. The works of Amancio Alcorta show a strong influence in European Romantic music, while the Sonate Op. 48 by Alberto Williams shows influence of Argentine creole folklore within the European structure. Angel Lasala abandoned the structure of European forms of big scope, typical of the end of the nineteenth century and featured aboriginal elements supported by a simple texture and harmony. Supported by a description of the historic events that led to the ratification of the Argentine Nation, this study connects the development of social stratums, and the relation between racial makeup and its different musical manifestations, with the growth of a National identity and a correspondent musical aesthetic.

No description available.

Williams-Beuren Syndrome (WBS) is an autosomal dominant neurodevelopmental disorder caused by hemizygous deletion of a 1.5 Mb region on chromosome 7q11.23. Symptoms are numerous and include behavioural and cognitive components. One of the deleted genes, GTF2IRD1, a putative transcription factor, has been implicated in the neurological features of WBS by studying patients with atypical deletions of 7q11.23. Gtf2ird1-targeted mice have features consistent with the WBS phenotype, namely reduced innate fear and increased sociability. To identify neural targets of GTF2IRD1, microarray analyses were performed comparing gene expression in whole brains of Gtf2ird1-/- and wildtype (WT) mice at embryonic day 15.5 and at birth. Overall, the changes in gene expression in the mutant mice were not striking, with most falling in the range of 0.3 to 2 fold. qRT-PCR was used to verify the expression levels of candidate genes and examination of verified genes revealed that most were located on chromosome 5, within 50 Mb of Gtf2ird1. Expression of these candidate genes in Gtf2ird1-/- mice was found to be the same as in WT 129S1/SvImJ mice, indicating the differences were the result of flanking chromosomal material from the, 129-derived, R1 ES cells from which the Gtf2ird1-/- mice were generated, and that expression differences were unrelated to Gtf2ird1 dosage. Further analysis found that while many genes showed decreased expression using primers targeting the 3’ UTR, expression of upstream exons was not affected. Transcripts using alternative polyadenylation sites were identified using 3’ RACE, and qRT-PCR showed that expression of different 3’ UTR isoforms can occur in a strain specific manner. Expression analysis of previously identified GTF2IRD1 targets also failed to demonstrate an in vivo effect. In summary, I was unable to find any in vivo neuronal targets of this putative transcription factor, despite its robust expression in the developing rodent brain.

Williams-Beuren Syndrome (WBS) is an autosomal dominant neurodevelopmental disorder caused by hemizygous deletion of a 1.5 Mb region on chromosome 7q11.23. Symptoms are numerous and include behavioural and cognitive components. One of the deleted genes, GTF2IRD1, a putative transcription factor, has been implicated in the neurological features of WBS by studying patients with atypical deletions of 7q11.23. Gtf2ird1-targeted mice have features consistent with the WBS phenotype, namely reduced innate fear and increased sociability. To identify neural targets of GTF2IRD1, microarray analyses were performed comparing gene expression in whole brains of Gtf2ird1-/- and wildtype (WT) mice at embryonic day 15.5 and at birth. Overall, the changes in gene expression in the mutant mice were not striking, with most falling in the range of 0.3 to 2 fold. qRT-PCR was used to verify the expression levels of candidate genes and examination of verified genes revealed that most were located on chromosome 5, within 50 Mb of Gtf2ird1. Expression of these candidate genes in Gtf2ird1-/- mice was found to be the same as in WT 129S1/SvImJ mice, indicating the differences were the result of flanking chromosomal material from the, 129-derived, R1 ES cells from which the Gtf2ird1-/- mice were generated, and that expression differences were unrelated to Gtf2ird1 dosage. Further analysis found that while many genes showed decreased expression using primers targeting the 3’ UTR, expression of upstream exons was not affected. Transcripts using alternative polyadenylation sites were identified using 3’ RACE, and qRT-PCR showed that expression of different 3’ UTR isoforms can occur in a strain specific manner. Expression analysis of previously identified GTF2IRD1 targets also failed to demonstrate an in vivo effect. In summary, I was unable to find any in vivo neuronal targets of this putative transcription factor, despite its robust expression in the developing rodent brain.

Diss.--Giessen (Allemagne)--Univ., 2000. / Bibliogr. p. 231-254.

No description available.

Thesis (Ed.D.)--Teachers College, Columbia University, 1975. / Typescript; issued also on microfilm. Sponsor: Thomas J. Manning. Dissertation Committee: Maxine Greene, . Includes bibliographical references (leaves 186-215).

Thesis (M.F.A.)--University of Wisconsin--Madison, 1981. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaf [96]).

Thesis (Ph. D.)--University of Wisconsin--Madison, 1957. / Typescript. Abstracted in Dissertation abstracts, v. 17 (1957) no. 10, p. 2272-2273. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 326-335).