Submitted by Micheli Abreu (mabreu@fiocruz.br) on 2016-02-25T17:02:49Z No. of bitstreams: 1 Gustavo_Dantas_EPSJC_Mestrado_2015.pdf: 1635389 bytes, checksum: 88bec30d05b400c61849619bdc1e3030 (MD5) / Approved for entry into archive by Renata Azeredo (renataazeredo@fiocruz.br) on 2016-02-29T16:09:43Z (GMT) No. of bitstreams: 1 Gustavo_Dantas_EPSJC_Mestrado_2015.pdf: 1635389 bytes, checksum: 88bec30d05b400c61849619bdc1e3030 (MD5) / Made available in DSpace on 2016-02-29T16:09:43Z (GMT). No. of bitstreams: 1 Gustavo_Dantas_EPSJC_Mestrado_2015.pdf: 1635389 bytes, checksum: 88bec30d05b400c61849619bdc1e3030 (MD5) Previous issue date: 2015 / Fundação Oswaldo Cruz. Escola Politécnica de Saúde Joaquim Venâncio. Programa de Pós-Graduação em Educação Profissional em Saúde. / Este estudo se debruçou sobre o cenário, as contradições, e as intencionalidades políticas que permeiam a Política de Formação dos Agentes Comunitários de Saúde (ACS), institucionalizada a partir do ano de 2004. O objetivo foi analisar os processos e relações que levaram o município de Recife a realizar a 2ª e 3ª etapas da formação técnica dos ACS nos anos de 2011 e 2012 para cerca de 1.500 trabalhadores. Trata-se de um estudo qualitativo, com referencial metodológico crítico, histórico e dialético, realizado por meio de análises de documentos e entrevistas com perguntas semiestruturadas, junto à sujeitos chaves na estruturação do da 2ª e 3ª etapas do curso Técnico de ACS nessa localidade, utilizando para análise dos dados a técnica de análise de conteúdo a partir do referencial de Bardin. Visou-se, através das informações colhidas, mapear as forças políticas envolvidas neste processo e que protagonizaram disputas neste cenário, utilizando o conceito de Hegemonia trazido por Antônio Gramsci como aporte teórico à essa compreensão. Os resultados expressaram a existência de quatro forças políticas disputando o processo formativo, alinhadas à concepções de políticas de Saúde que incidiram historicamente na formulação deste trabalhador. Os movimentos das alianças realizadas entre essas forças políticas foram decisivos na materialização da conclusão do curso. Espera-se, que este trabalho possa fomentar discussões sobre os rumos da política de Formação desta categoria, na perspectiva de contribuir para a construção de ações concretas para sua materialização enquanto Política Pública. / This study set out to investigate the setting, the contradictions, and the political intentions that have pervaded the Training Policies for Community Health Workers (CHW), which came into force from 2004. Our aim was to analyze the processes and relationships that led the city of Recife to implement the 2nd and 3rd stages of the technical training course for CHWs in 2011 and 2012 for around 1,500 workers. This was a qualitative study with a critical, historical and dialectical methodological framework, conducted through document reviews and semi-structured interviews with the key personnel involved in structuring of the 2nd and 3rd stages of the technical course for CHWs. Data was analyzed using Bardin’s technique. Through the information gathered, we set out to chart the political forces involved in this process, who had staged disputes within this scenario, using the concept of hegemony as developed by Antonio Gramsci as a theoretical contribution towards a greater understanding. The results we obtained conveyed the existence of four political forces vying for the training process, aligned with the concepts of health policies, which have rendered an historical influence over the formulation of this worker. The activities undertaken by the alliances formed between these political forces were decisive in ensuring the conclusion of the course. It is hoped that this work may foster discussions on the course of training policies within this field, in order to contribute to the construction of concrete actions for its materialization as Public Policy.

Face à la finitude des ressources de la terre et de sa capacité d’absorption de la pollution, le développement d’écobétons pour un futur industrialisé durable représente un défi majeur de la science du béton moderne. En raison de sa nature hétérogène complexe, les propriétés macroscopiques du béton dépendent fortement des constituants de sa microstructure (ex. silicates de calcium hydratés [C–S–H], Portlandite, inclusions anhydres, porosité, agrégats, etc.). De plus, la nécessité d’une exploitation rapide et optimale des matériaux cimentaires émergents dans les applications industrielles demande de nos jours une meilleure compréhension de leurs particularités chimico-mécaniques à l’échelle micrométrique. Cette thèse vise à développer une méthode de pointe de couplage de la nanoindentation et de la spectroscopie quantitative aux rayons X à dispersion d'énergie (NI-QEDS), puis à fournir une caractérisation chimico-mécanique originale des phases microstructurales présentes dans les matrices réelles de ciments mélangés. La combinaison d’analyses NI-QEDS statistiques et déterministes a ainsi permis d’élargir la compréhension des systèmes avec ciment Portland et ajouts cimentaires (ACs) conventionnels ou alternatifs. Plus spécifiquement, l’étude des C–(A)–S–H (C–S–H incluant l’aluminium ou non) dans différents systèmes à base de ciments mélangés a montré des compositions différentes pour cet hydrate (variations dans les taux de Ca, Si, Al, S et Mg), mais ses propriétés mécaniques n’ont pas été significativement affectées par l’incorporation des ACs dans des dosages typiques. Les résultats présentés ont aussi démontré le rôle important des autres phases imbriquées dans la matrice de C–(A)–S–H, soit les inclusions anhydres dures (ex. le clinker et les ACs) et les autres hydrates tels que la Portlandite et les hydrates riches en aluminium (ex. les carboaluminates) avec des propriétés mécaniques plus élevées que celles des C–(A)–S–H. La thèse est basée sur cinq articles couvrant : (1) une analyse NI-EDS de systèmes incorporant des volumes élevés de pouzzolanes naturelles; (2) le développement de la méthode NI-QEDS; des analyses statistiques NI-QEDS (3) de systèmes avec cendres volantes et laitier, et (4) d’un système combinant ciment, calcaire et argile calcinée; et (5) une exploration déterministe NI-QEDS de systèmes conventionnels et alternatifs incorporant la poudre de verre, le métakaolin, le laitier ou la cendre volante. Finalement, en plus d’avancer les derniers modèles et méthodes micromécaniques, l’outil développé a fourni une perception chimico-mécanique originale des phases microstructurales et de leur arrangement. Le dévoilement de la signature chimico-mécanique de ces pâtes de ciments mélangés particulièrement complexes offre un savoir unique pour l’ingénierie des bétons de demain. / Abstract : Facing the limitedness of the earth’s resources and pollution absorption capacity, the development of eco-concrete for a sustainable industrialized future is one of the major challenges of modern concrete science. Due to its complex heterogeneous nature, the macro-scale properties of concrete strongly depend on the microstructure constituents (e.g., calcium-silicate-hydrates [C–S–H], Portlandite, anhydrous inclusions, porosity, aggregates, etc.). Moreover, the need for rapid and optimal exploitation of emerging binding materials in industrial applications urges today a better understanding of their chemo-mechanical features at the micrometer scale. This thesis aims at developing a state-of-the-art method coupling NanoIndentation and Quantitative Energy-Dispersive Spectroscopy (NI-QEDS), and providing an original chemo-mechanical characterization of the microstructure phases in highly heterogeneous matrices of real blended-cement pastes. The combination of statistical and deterministic NI-QEDS analysis approaches opened new research horizons in the understanding of Portland-cement systems incorporating conventional and alternative supplementary cementitious materials (SCMs). More specifically, the investigations of C–(A)–S–H (C–S–H including aluminum or not) in different blended-cement systems showed variable compositions for this hydrate (i.e., Ca, Si, Al, S and Mg contents), but the mechanical properties were not significantly affected by the incorporation of SCMs in typical dosages. The presented results also showed the important role of the other phases embedded in the C–(A)–S–H matrix, i.e., hard anhydrous inclusions (e.g., clinker and SCMs) and other hydrates such as Portlandite and Al-rich hydrates (e.g., carboaluminates) with mechanical properties higher than those of the C–(A)–S–H. The thesis is based on five articles focusing on: (1) the NI-EDS investigation of high-volume natural pozzolan systems; (2) the development of the NI-QEDS method; the statistical NI-QEDS analyses of (3) fly ash and slag blended-cement systems and of (4) a limestone-calcined-clay system; and (5) the deterministic NI-QEDS exploration of alternative and conventional systems incorporating glass powder, metakaolin, slag or fly ash. Finally, the developed tool not only advanced the latest micromechanical methods and models, but also provided original chemo-mechanical insights on the microstructure phases and their arrangement. Unveiling the chemo-mechanical signature of these highly-complex blended cement pastes further provided unique knowledge for engineering concretes for tomorrow.

The aim of this diploma thesis is to create universal application able to visualize M2M data and allows remote management of smart sensors using TR-069 protocol. First part of this thesis contains comprehensive evaluation of TR-069 standard and OSGi platform. Next, extensive analysis of embedded databases with detailed description of SQLite platform is provided. Auto-configuration server genieacs and modus TR-069 client, two parts needed for the proper run of remote configuration, are described in more detail in following section. Practical part of this thesis contains description of all created OSGi bundles together with communication interfaces. Moreover, the description of designed database and developed user interface is given.

No description available.

No description available.

La phospholipase A2 liée aux lipoprotéines (Lp-PLA2) est une biomarqueur de plusieurs maladies inflammatoires et une niveau sérique élevé est associé à l’instabilité de la plaque artérioscléreuse. Comme son nom l’indique, la Lp-PLA2 est liée aux lipoprotéines plasmatiques (LDL et HDL) et son rôle est de prévenir l’accumulation de phospholipides oxidés a la surface des lipoprotéines. Toutefois, les produits de dégradation des phospholipides oxidés par la Lp-PLA2 - le lysophosphatidyl choline par les acides gras oxidés peuvent aussi promouvoir l’inflammation. Mieux comprendre le métabolisme de la Lp-PLA2 pourrait nous permettre de mieux apprécier son rôle dans la formation d’une plaque artérioscléreuse instable, car des études antérieures ont démontré une forte expression de la Lp-PLA2 dans la plaque. De plus, il existe une forte corrélation entre les niveaux et l’activité plasmatiques de la Lp-PLA2 et la maladie coronarienne, les accidents cérébraux-vasculaires et la mortalité cardiaque. L’inhibition de la Lp-PLA2 avec une petite molécule, le darapladib, n’a pas démontré de bénéfice sur les évènements cardiovasculaires dans deux études cliniques. Cette thèse présentera d’abord une revue de la littérature sur la Lp-PLA2 et les maladies cardiovasculaires et les deuxième et troisième chapitres, une étude clinique réalisée sur des patients avec un syndrome coronarien aigu. / Lipoprotein associated phospholipase A2 (Lp-PLA2) is a biomarker of several inflammatory diseases and syndromes. An elevated Lp-PLA2 level is associated with unstable atherosclerotic plaques. Bound to plasma lipoproteins (LDL and HDL), Lp-PLA2 prevents the formation of biologically active oxidized phospholipids on their surface such as oxidized phosphatidylcholine (oxPC). Nevertheless, the products of Lp-PLA2 action, lysophosphatidylcholine (LPC) and non-esterified fatty acids (NEFA) are both known to aggravate inflammation. Thus, understanding the metabolism of Lp-PLA2 could help us better understand its role in plaque formation, as studies have shown high expression of Lp-PLA2 and LPCs in unstable plaques. Moreover, studies showed correlation between increased Lp-PLA2 mass and activity and increased risk of coronary artery disease, stroke, and death. The inhibition of Lp-PLA2 with a small molecule, Darapladib, has not demonstrated benefit in reduction of cardiovascular events in two clinical studies. Here, the first chapter will focus on Lp-PLA2 and cardiovascular disease in man, highlighting the latest updates in the literature. The second and third chapters will introduce experimental work on Lp-PLA2 in the setting of acute coronary syndrome.

Made available in DSpace on 2011-05-04T12:36:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2009 / Este estudo objetivou analisar o corpo docente do Curso de qualificação de Agentes Comunitários de Saúde do Estado de Mato Grosso, por meio da Escola de Saúde Pública de Mato Grosso esta iniciativa verificando a pertinência e adequação daqueles que foram responsáveis por esta capacitação no estado. No referencial teórico percorremos a trajetória das transformações econômicas e socioculturais vivenciadas no cenário brasileiro nas últimas décadas que estimularam a reorganização do sistema de saúde do país e no estado de Mato Grosso. A opção metodológica adotada foi de estudo descritivo tendo como foco a análise das características gerais e específicas dos docentes que atuaram na Regional de Saúde da Baixada Cuiabana no período entre 2006 e 2008. O estudo com a perspectiva de subsidiar a reformulação da Política de Formação profissional executada pela Escola de Saúde Pública de Mato Grosso. Evidenciou-se que o quadro de docentes, em sua totalidade, é composto por enfermeiros que atuam nas Equipes de Saúde da Família. O maior contingente é constituído de mulheres, estão na faixa etária de 30 e 50 anos; residem em sua maioria em Cuiabá. Observa-se à ausência de envolvimento dos profissionais médicos também responsável pela capacitação / qualificação dos Agentes. O maior contingente de docentes tem mais de 11 anos de formado, com qualificação (pós-graduação) em saúde pública e poucos na área da Saúde da Família, possuem vinculo de trabalho com as Secretarias Municipais de Saúde, através de contratos temporários caracterizando a precarização do trabalho. O vinculo de trabalho com a Escola se deu de forma informal. O duplo vínculo é uma característica muito comum, a atividade docente acaba por ser exercida em condições pouco favoráveis (nas brechas das jornadas de trabalho), estão motivados pela necessidade de complementação salarial. Contudo acredita-se que a maioria dos docentes utiliza os critérios de avaliação compatível com Projeto Político Pedagógico da Escola de Saúde Pública de Mato Grosso. / This study aimed at analyzing the teaching staff of the Training Course for Health Community Agents of the State of Mato Grosso, through the Public Health School of Mato Grosso. This initiative verified the pertinence and adequacy of those who were responsible for this training in the state. In the theoretical referential we followed the path of the economic and socio-cultural changes in the Brazilian scenery in the last decades that fostered the reorganization of the health system of the country and in the State of Mato Grosso. The methodological option adopted was that of a descriptive study focusing on the analysis of the general and specific characteristics of the teachers that worked in the Health District System of Baixada Cuiabana from 2006 to 2008. The study with the perspective of helping in the reformulation of the Professional Upbringing Policy was carried out by the Public Health School of Mato Grosso. It was shown that the teacher`s staff in its whole, is composed by nurses that work in the Family Health Teams. Most of them are women that live in Cuiabá with ages ranging from 30 and 50 years. The absence of the involvement of the doctors that are also responsible for the qualification/training of the Agents is observed. Most of the teachers finished their graduation course more than eleven years ago, and had their postgraduation in Public Health and few in the Family Health area, are linked to the Health Departments, through temporary contracts showing how the job is precarious. The employment relation with the school occurred in an informal way. The double employment linkage is a very common characteristic, in the end, the teaching activity is performed in unfavorable conditions (when they are not working), and they are motivated by the need for adding more money to the salary. Yet, it is believed that most of the teachers use the evaluation criteria compatible with the Pedagogical Political Project of the Public Health School of Mato Grosso.

This diploma thesis deals with design, realization and analysis of security and surveillance systems for buildings and spaces containing advanced components. One of the main design's parts is dedicated to intruder alarm system, access system, attendance and CCTV systems with the possibility of automatic motion tracking. Controlling and monitoring of particular subsystems is possible both locally and remotely from a computer via a web interface or by means of a software. The access to camera system from a mobile phone is also possible. IAS/ACS systems also enable controlling and transferring information about their state via SMS. The designed system was realized completely and its operating was demonstrated. The realization is described in detail including illustration of configuration of particular components. A security analysis and a possible future development of the project is summarized in the conclusion.

Christian Education South Africa (CESA), formerly known as Accelerated Christian Education (South Africa) or ACE(SA), represents a significant number of evangelical Christian schools in South Africa. Most CESA schools are multiracial· and part of charismatic fellowships. The purpose of this study was to investigate CESA {its roots, philosophy of education and methodology) and to evaluate the quality of Christian education offered at CESA schools. Firstly, 'sound Christian education' was defined. Secondly, a model for assessing Christian education was developed. The SAPPAB model with its six criteria (spiritual, academic, physical, practical, administrative and balance) assess both the biblical and t educational 'soundness' of an education programme . . Information was gathered over six years by way of interviews, surveys, ethnographic and in-depth case studies. Evaluations included individual CESA schools, CESA as an organization and the ACE programme. The major finding was that individual CESA schools do contribute meaningfully to sound Christian education, but that the organization as such lost its vision and its influence. / Educational Studies / M. Ed. (History of Education)

Christian Education South Africa (CESA), formerly known as Accelerated Christian Education (South Africa) or ACE(SA), represents a significant number of evangelical Christian schools in South Africa. Most CESA schools are multiracial· and part of charismatic fellowships. The purpose of this study was to investigate CESA {its roots, philosophy of education and methodology) and to evaluate the quality of Christian education offered at CESA schools. Firstly, 'sound Christian education' was defined. Secondly, a model for assessing Christian education was developed. The SAPPAB model with its six criteria (spiritual, academic, physical, practical, administrative and balance) assess both the biblical and t educational 'soundness' of an education programme . . Information was gathered over six years by way of interviews, surveys, ethnographic and in-depth case studies. Evaluations included individual CESA schools, CESA as an organization and the ACE programme. The major finding was that individual CESA schools do contribute meaningfully to sound Christian education, but that the organization as such lost its vision and its influence. / Educational Studies / M. Ed. (History of Education)