The diploma thesis deals with impact of regulatory measures on bank credit activity. Banking regulatory frameworks Basel II and III are approximated via selected capital requirements. The empirical analysis is based on a panel regression analysis with fixed effects. The sample consists of 4313 European banks. Determinants of supply are selected indicators of bank characteristics. Factors of demand are taken into account via macroeconomic fundamentals. The impact of monetary policy is examined through a three-month interbank interest rate. The results of the empirical analysis point to the importance of regulatory measures in relation to credit activity. Subsequently, the robustness analysis deals with the closer impact depending on the size of the bank and the operating market.

Title: Modified games -integrative factor mentally affected. Goal of thesis: To enable to persons with mental infliction of achievement maximum self- realization, satiation of the basic human needs (biological, social and vegetative) and purposeful incorporation to the society. Method: The empirical research - the application of sport kinetic games with choice set of mentally affected boys in terms club of sport games together with pupils common school. Outcomes: My conclusions of this work confirm supposed contribution of play and games activities like the effective tool for an integration of mentally affected pupils Key words: Special needs, disability, integration, inclusion, kinetic activity, gaming activity.

Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Author: Cristina Paredes de la Red Supervisor: prof. PharmDr. Martin Doležal, Ph.D. Title of diploma thesis: Synthesis and antiinfective evaluation of substituted N-(pyrazine-2- yl)benzenesulfonamide Tuberculosis (TB) is among the ten leading causes of death, especially in developing countries. Even though it is an old disease with established treatment regimen, there has been an increased resistance to anti-TB drugs 1 . The anti-tubercular pyrazinamide has caught the attention of researchers as the different theories for its mechanism of action have made it an interesting entity for further investigation. Here we will discuss N-(pyrazine-2-yl)benzenesulfonamides (General structure is presented in the Figure below) as a new derivatization approach based on synergism methodology between pyrazinamide and sulfonamides. Sulfonamides exert their antimicrobial effect by competitive inhibition of folic acid synthesis and subsequent inhibition of bacterial growth and reproduction 18 . I have contributed to the synthesis and purification of 8 compounds in a series of total 22 N- pyrazinylsulfonamides. Two of the prepared compounds showed activity against Mycobacterium kansasii [2a (MIC...

This thesis deals with the before-, during- and after- reading activities when working with text in teaching literature in grades 6-9. The first part describes results from testing the critical literacy of Czech students in the PISA 2009 international comparison, as well as levels of critical literacy and its place in the Framework Education Programme for Elementary Education. The reasons for using these activities and examples of them are also discussed. In the practical part, I carried out research using questionnaires to find out if and how often teachers use these types of activities and I have provided examples of those used. Next I wanted to find out which types of readers the teachers use and how these readers contribute to a student's reading literacy development.

The diploma thesis gives the information of the preferences of locomotive activities at chosen groups of the students of South Bohemian University. The preferences of the students that study Physical Education have been compared to the preferences of the students of other pedagogical subjects and also the mutual comparison of locomotive activities of women and men has been done. The research has been performed in a questionnaire form. The results have shown that young people currently prefer both traditional sports, and new, modern kinds of sports, developed in the last ten years. These activities also reflect the development of the society and economics, and also technical possibilities in new sport facilities.

This thesis deals with the life of current seniors in the country with regard to their leisure activities. The first part defines key terms, such as aging and old age; senior; active aging; ageism; Leisure, its functions and the factors that affect it. The second section deals with the different types of organized and unorganized leisure activities for seniors. The main part is the qualitative research of the life of seniors in the country. The research was conducted by interviewing fifteen seniors living in rural areas.

Abstrakt/abstract Předložená diplomová práce se zabývá městskými a příměstskými cyklostezkami v Praze. Ve své části teoretické shrnuje terminologii daného okruhu, vymezuje pojem cyklostezka, cyklotrasa, cyklopruh aj. Dále specifikuje pojmy s daným tématem související (volný čas, zájmová činnost, pohybová rekreace aj.) V samostatných kapitolách se věnuje historii a současnému stavu cyklostezek, následně pak legislativním normám. Práce vymezuje také druhy pohybových aktivit, které je možné na cyklostezkách provozovat (cyklistika, chůze, in-line bruslení aj.) V praktické části seznamuje s metodami výzkumu a výsledky pozorování a dotazníkového šetření. Ve svých závěrech se snaží charakterizovat uživatele cyklostezek, zkoumá jejich motivaci, četnost návštěv cyklostezek, druhy provozovaných aktivit. Zajímá se o nároky na kvalitu a vybavení cyklostezek, shrnuje pozitiva i negativa cyklostezek v Praze. V závěru nabízí přehled městských a příměstských cyklostezek v Praze. Submitted thesis deals with urban and suburban cycle tracks in Prague. The theoretical part concerns terminology of the given topic and defines terms such as cycle track, cycle route, cycle lane etc. Furthermore, it specifies terms closely related to the topic (free time, hobbitry, kinetic recreation etc.) Other chapters address the history and...

Title Principles of nutrition for leisure physical activities Objectives: The aim of this study was to determine how the students of Charles University compliance diet and whether they comply with the principles of good nutrition for leisure activities. The operational objective was also to their assess knowledge in a knowledge test, which was part of the research. Methods: In this work, a quantitative method was used. Obtain the necessary information has been compiled questionnaire was divided into four parts and focused on principles of good nutrition. The group of respondents consisted of 215 students from Charles University, which was established premise that deal with leisure activities. Collected data were processed and interpreted using the statistic characteristics and for better clarity were graphically depicted. Results: It was found that students under the age of 35 years, which took part in the research, have a good theoretical knowledge of the principles of healthy nutrition. However, in a practical sense some nutrition principles are not respected.The main shortcomings may include that more than half of the students had never thought about what the majority composition should have a diet which they should have been accepted after the physical stress, as well as the inclusion of...

This thesis reports the syntheses and biological activities of benzo- and thieno-fused 7-deazapurine ribonucleosides, which were designed as extended analogues of potent cytostatic 6-hetaryl-7-deazapurine or 6-amino-7-hetaryl-7-deazapurine ribonucleosides. First of all, multigram syntheses of (di)chloro-9H-pyrimido[4,5-b]indoles from simple chloro- nitrobenzenes were developed. Pyrimidoindoles were successfully glycosylated and used for the synthesis of 4-hetaryl-6-chloro-, 4,6-bis(hetaryl)-, 4-amino-6-hetaryl-, 4-amino-5-hetaryl- and 4-susbtituted pyrimido[4,5-b]indole ribonucleosides. Hetaryl groups were introduced by Suzuki or Stille cross-coupling reaction. Standard catalysts and conditions were used for reaction in position 4. To observe some reactivity of unreactive chlorine in position 6, modification of standard protocol was necessary. Screening of several ligands had been done and Buchwald ligand X-Phos was found to be optimal. As chlorine in position 4 is activated for nucleophilic substitution, amino and dimethylamino derivatives were prepared by reaction with aqueous ammonia and dimethylamine, respectively. 4-Alkyl derivatives were synthesized by palladium-catalyzed alkylation with trialkylaluminium or by Negishi coupling in case of cyclopropyl derivative. Desired free nucleosides were...

This thesis deals with the topic: "Physical activity of persons employed with a focus on the teaching profession." In the theoretical part concepts related to history and the intensity of teaching, teachers and related mental stress health risks. are characterized. We also deal with the influence of physical activity on human health, and the ability to reduce the occurrence of various health risks. The aim of the thesis is to monitor physical activity among teachers in kindergarten, Basic school, including school with small classes and high school. It is assessed on the basis of a standardized questionnaire IPAQ-long and by monitoring using pedometers Yamax Digiwalker SW 700th The results found physical activity are compared with recommendations for physical activity and divided into categories according to the classification PA Tudor-Locke and Bassett.